KEGG   Aotus nancymaae (Ma's night monkey): 105704869
Entry
105704869         CDS       T10127                                 
Symbol
MAPK12
Name
(RefSeq) mitogen-activated protein kinase 12
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
anan  Aotus nancymaae (Ma's night monkey)
Pathway
anan01522  Endocrine resistance
anan04010  MAPK signaling pathway
anan04015  Rap1 signaling pathway
anan04068  FoxO signaling pathway
anan04071  Sphingolipid signaling pathway
anan04114  Oocyte meiosis
anan04148  Efferocytosis
anan04218  Cellular senescence
anan04261  Adrenergic signaling in cardiomyocytes
anan04370  VEGF signaling pathway
anan04380  Osteoclast differentiation
anan04550  Signaling pathways regulating pluripotency of stem cells
anan04611  Platelet activation
anan04613  Neutrophil extracellular trap formation
anan04620  Toll-like receptor signaling pathway
anan04621  NOD-like receptor signaling pathway
anan04622  RIG-I-like receptor signaling pathway
anan04625  C-type lectin receptor signaling pathway
anan04657  IL-17 signaling pathway
anan04658  Th1 and Th2 cell differentiation
anan04659  Th17 cell differentiation
anan04660  T cell receptor signaling pathway
anan04664  Fc epsilon RI signaling pathway
anan04668  TNF signaling pathway
anan04670  Leukocyte transendothelial migration
anan04714  Thermogenesis
anan04722  Neurotrophin signaling pathway
anan04723  Retrograde endocannabinoid signaling
anan04728  Dopaminergic synapse
anan04750  Inflammatory mediator regulation of TRP channels
anan04912  GnRH signaling pathway
anan04914  Progesterone-mediated oocyte maturation
anan04917  Prolactin signaling pathway
anan04926  Relaxin signaling pathway
anan04932  Non-alcoholic fatty liver disease
anan04933  AGE-RAGE signaling pathway in diabetic complications
anan04935  Growth hormone synthesis, secretion and action
anan04936  Alcoholic liver disease
anan05014  Amyotrophic lateral sclerosis
anan05020  Prion disease
anan05022  Pathways of neurodegeneration - multiple diseases
anan05132  Salmonella infection
anan05133  Pertussis
anan05135  Yersinia infection
anan05140  Leishmaniasis
anan05142  Chagas disease
anan05145  Toxoplasmosis
anan05152  Tuberculosis
anan05161  Hepatitis B
anan05163  Human cytomegalovirus infection
anan05167  Kaposi sarcoma-associated herpesvirus infection
anan05169  Epstein-Barr virus infection
anan05170  Human immunodeficiency virus 1 infection
anan05171  Coronavirus disease - COVID-19
anan05205  Proteoglycans in cancer
anan05208  Chemical carcinogenesis - reactive oxygen species
anan05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
anan05415  Diabetic cardiomyopathy
anan05417  Lipid and atherosclerosis
anan05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:anan00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    105704869 (MAPK12)
   04015 Rap1 signaling pathway
    105704869 (MAPK12)
   04370 VEGF signaling pathway
    105704869 (MAPK12)
   04668 TNF signaling pathway
    105704869 (MAPK12)
   04068 FoxO signaling pathway
    105704869 (MAPK12)
   04071 Sphingolipid signaling pathway
    105704869 (MAPK12)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    105704869 (MAPK12)
  09143 Cell growth and death
   04114 Oocyte meiosis
    105704869 (MAPK12)
   04218 Cellular senescence
    105704869 (MAPK12)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    105704869 (MAPK12)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    105704869 (MAPK12)
   04613 Neutrophil extracellular trap formation
    105704869 (MAPK12)
   04620 Toll-like receptor signaling pathway
    105704869 (MAPK12)
   04621 NOD-like receptor signaling pathway
    105704869 (MAPK12)
   04622 RIG-I-like receptor signaling pathway
    105704869 (MAPK12)
   04625 C-type lectin receptor signaling pathway
    105704869 (MAPK12)
   04660 T cell receptor signaling pathway
    105704869 (MAPK12)
   04658 Th1 and Th2 cell differentiation
    105704869 (MAPK12)
   04659 Th17 cell differentiation
    105704869 (MAPK12)
   04657 IL-17 signaling pathway
    105704869 (MAPK12)
   04664 Fc epsilon RI signaling pathway
    105704869 (MAPK12)
   04670 Leukocyte transendothelial migration
    105704869 (MAPK12)
  09152 Endocrine system
   04912 GnRH signaling pathway
    105704869 (MAPK12)
   04914 Progesterone-mediated oocyte maturation
    105704869 (MAPK12)
   04917 Prolactin signaling pathway
    105704869 (MAPK12)
   04926 Relaxin signaling pathway
    105704869 (MAPK12)
   04935 Growth hormone synthesis, secretion and action
    105704869 (MAPK12)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    105704869 (MAPK12)
  09156 Nervous system
   04728 Dopaminergic synapse
    105704869 (MAPK12)
   04723 Retrograde endocannabinoid signaling
    105704869 (MAPK12)
   04722 Neurotrophin signaling pathway
    105704869 (MAPK12)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    105704869 (MAPK12)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    105704869 (MAPK12)
  09159 Environmental adaptation
   04714 Thermogenesis
    105704869 (MAPK12)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    105704869 (MAPK12)
   05208 Chemical carcinogenesis - reactive oxygen species
    105704869 (MAPK12)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    105704869 (MAPK12)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    105704869 (MAPK12)
   05161 Hepatitis B
    105704869 (MAPK12)
   05171 Coronavirus disease - COVID-19
    105704869 (MAPK12)
   05163 Human cytomegalovirus infection
    105704869 (MAPK12)
   05167 Kaposi sarcoma-associated herpesvirus infection
    105704869 (MAPK12)
   05169 Epstein-Barr virus infection
    105704869 (MAPK12)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    105704869 (MAPK12)
   05135 Yersinia infection
    105704869 (MAPK12)
   05133 Pertussis
    105704869 (MAPK12)
   05152 Tuberculosis
    105704869 (MAPK12)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    105704869 (MAPK12)
   05140 Leishmaniasis
    105704869 (MAPK12)
   05142 Chagas disease
    105704869 (MAPK12)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    105704869 (MAPK12)
   05020 Prion disease
    105704869 (MAPK12)
   05022 Pathways of neurodegeneration - multiple diseases
    105704869 (MAPK12)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    105704869 (MAPK12)
   05418 Fluid shear stress and atherosclerosis
    105704869 (MAPK12)
   05415 Diabetic cardiomyopathy
    105704869 (MAPK12)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    105704869 (MAPK12)
   04932 Non-alcoholic fatty liver disease
    105704869 (MAPK12)
   04933 AGE-RAGE signaling pathway in diabetic complications
    105704869 (MAPK12)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    105704869 (MAPK12)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:anan01001]
    105704869 (MAPK12)
Enzymes [BR:anan01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     105704869 (MAPK12)
Protein kinases [BR:anan01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   105704869 (MAPK12)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH Kdo Kinase-like Haspin_kinase
Other DBs
NCBI-GeneID: 105704869
NCBI-ProteinID: XP_012289781
Ensembl: ENSANAG00000034296
UniProt: A0A2K5EJJ7
LinkDB
Position
Unknown
AA seq 367 aa
MSSPPPARSGFYRQEVTKTAWEVRVVYRDLQPVGSGAYGAVCSAVDSRTGAKVAIKKLYR
PFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLM
KHEKLGEDRIQFLVYQMLKGLKYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQADS
EMTGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIMK
VTGTPPAEFVQRLQSDEAKNYMKGLPELEKKDFASILTNASPLAVNLLEKMLVLDAEQRV
TAAEALAHPYFESLHDTEDEPQAQKYDDSFDDVDRTLDEWKRVTYKEVLSFKPPRQLGAR
VSKETAL
NT seq 1104 nt   +upstreamnt  +downstreamnt
atgagctctccgccgcccgcccgcagtggcttttaccgccaggaggtgaccaagacggcc
tgggaggtgcgcgtcgtgtaccgggacctgcagcccgtgggctcgggcgcctatggcgcg
gtgtgctccgcggtggacagccgcaccggcgccaaggtggccatcaagaagctgtaccgg
cccttccagtccgagctgttcgccaagcgcgcctaccgcgagctgcgcctgctcaagcac
atgcgccacgagaacgtgatcgggctgctggacgtattcactcctgatgagactctggat
gacttcacggacttttacctggtgatgccattcatgggcactgacctggggaagctcatg
aagcacgagaagctgggagaggaccggattcagttcctcgtgtaccagatgctgaagggg
ctgaagtatatccacgctgccggcatcatccacagagacctgaagcctggcaacctggct
gtgaacgaagactgtgaactgaagatcctggactttggcctggccaggcaggctgacagc
gagatgactgggtatgtggtgactcggtggtaccgggcgcccgaggtcatcttgaattgg
atgcgctacacacagacggtggacatctggtctgtgggctgcatcatggcagagatgatc
acaggcaagacattgttcaagggcagcgaccatctggaccagctgaaagagatcatgaag
gtgacagggacacctccagctgagtttgtgcagcggctgcagagcgatgaggccaagaac
tacatgaagggcctccctgagttggagaagaaggattttgcctccatcctgaccaatgca
agccctctggctgtgaacctcctggagaagatgctggtgctggacgcggagcagcgggtg
acggcagccgaggcgctggctcacccctactttgagtccctgcacgacacggaagatgag
ccccaggcccagaagtatgatgactcctttgacgatgtggaccgcacgctggatgaatgg
aagcgtgtcacttacaaagaagtgctcagcttcaagcctccccggcagctgggggccagg
gtctccaaggagacggctctgtga

DBGET integrated database retrieval system