Aotus nancymaae (Ma's night monkey): 105705897
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Entry
105705897 CDS
T10127
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X3
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
anan Aotus nancymaae (Ma's night monkey)
Pathway
anan00310
Lysine degradation
anan01100
Metabolic pathways
anan05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
anan00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
105705897 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
105705897 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
anan03036
]
105705897 (DOT1L)
Enzymes [BR:
anan01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
105705897 (DOT1L)
Chromosome and associated proteins [BR:
anan03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
105705897 (DOT1L)
HMT complexes
Dot1-containing complex
105705897 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DOT1
Motif
Other DBs
NCBI-GeneID:
105705897
NCBI-ProteinID:
XP_012291255
Ensembl:
ENSANAG00000026868
LinkDB
All DBs
Position
Unknown
AA seq
1552 aa
AA seq
DB search
MEAPSPAVTYRAFAEAGFPARLELPGWSGSWWACGACPQGLGDKHHDAAHEIIETIRWVC
EEIPDLKLAMENYVLIDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSTG
LLRHILQQVYNHSVTDPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTDDDLFVDLGSG
VGQVVLQVAAATNCKHHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLS
EEWRERIANTSVIFVNNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLS
DIGTIMRVVELSPLKGSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQ
QRESKSNAATPTKGPEGKAAGPAEVPMDSGAEEEKAGAATVKKPSPSKARKKKLNKKGRK
MAGRKRGRPKKMSTANPERKPKKSQTALDLLHAQTVSQTAASSPQDAYRSPHSPFYQLPP
SVQRHSPNPLLVAPTPPALQKLLESFRVQYLQFLAYTKTPQYKASLQELLGQEKEKNAQL
LGTAQQLLSHCQAQKEEIRRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQSEQL
EQDNRALRSQSLQLLKARCEELQLDWATLSLEKLLKEKQALKSQISEKQRRCLELQISIV
ELEKSQRQQELLQLKSCVPPDDTPALHLRGKGALGRELEPDAGRLHLELDCAKFSLPHLS
SMSPELSMNGHAASYELCSALSRPSPKQDTPQYLASPLDQEVVPCTPSHGGRPRVEKLSG
LAVPDYTRLSPAKIVLRRHLSQDHAVPGRPAASELHPRAEHTKENGLPYQSPSVPSSMKL
SPQDPRPPSPGTLQLAGEKSSEKGLRERAYGSGGEPITSLPISIPLSTVQPNKLPVSIPL
ASVVLPSRAERARSTPSPVLQPRDPSSTLEKHIGANAHSAGSKSLALAPAGFSYAGSVAI
SGTLAGSPASLAPGAEPAALDESSSSGSLFATVGSRSSTPQHPLLLAQPRNSRPASPTHQ
LSSSPRLGGAAHGPLPEASKGDLPSDSGFSDPESEAKRRIVFTIATGTGGTKQSPSSKHS
PLTSSARGDCVPSHGQDSRKRGRRKRASTGTPSLTAGVSPKRRALPSVAGLFTQPSGSPL
NLNSMVSNINQPLEITAISSPETSLKSSPVPYQDHDQPPVLKKERPLSQTNGAHYSPLTS
DEEPGSEDEPSSARIERKIATISLESKSPPKTLENGGGVLGRRPAPAGEPVNSSKWKSTF
SPISDIGLAKAADSPLQAGPTLSQSSLFAFRPALEEPPADAKLAAHPRKGFPTSLSGADG
LSPSTNPANGCTFGGGLAAELSSHSFSDGASLPNKGPEAAGLSSPLGFPSQRAKEASDAN
PFLSKRQLDGLAGLKGEGGRGKEVGEGGLPLCGPADKTPLPTGKAAKARDRELDLKNGHN
LFISAAAVPPGGLLSGPGLAPAVSSAGGAGSSAQTHRPFLGPFPPGPQFALGPMALQANL
GSVAGSSVLQSLFSSVPAAAGLVHVSSAATRLTNSHAMGSFSGVAGSTVGGN
NT seq
4659 nt
NT seq
+upstream
nt +downstream
nt
atggaggctccatcacctgcagtcacgtaccgggcctttgcagaagcaggattcccagcc
aggctggagctcccaggctggagcggttcctggtgggcctgtggagcgtgtcctcagggg
ctcggggacaaacatcacgatgctgctcatgaaatcatcgagaccatccgatgggtctgt
gaagaaatcccggatctcaagctcgctatggagaattacgttttaattgactatgacacc
aaaagcttcgagagcatgcagaggctctgtgacaagtataaccgtgccatcgacagcatc
caccagctgtggaagggcaccacgcagcccatgaagctgaacacgcggccgtctaccggg
cttctgcgccacatcctgcagcaggtctacaaccactcggtgaccgaccccgagaagctc
aacaactacgaacccttctcccccgaggtgtacggggagacctccttcgacctggtggcc
cagatgatcgacgagatcaagatgactgacgatgacctgtttgtggacctggggagcggt
gtgggccaggttgtgctccaggtcgccgctgccaccaattgcaaacatcactatggcgtc
gagaaagcagacatcccggccaagtatgcggagaccatggaccgcgagttcaggaagtgg
atgaaatggtatggaaaaaagcatgcagaatacacattggagagaggcgatttcctctcg
gaagagtggagggagcgaattgccaacacgagtgttatatttgtgaataactttgccttt
ggtcctgaggtggatcaccagctgaaggagcggtttgcaaacatgaaggaaggtggcaga
atcgtgtcctcgaaaccctttgcacctctaaacttcagaataaacagtagaaacttgagt
gacatcggcaccatcatgcgtgtggtggagctgtcgcccctcaagggctcggtgtcatgg
acggggaagccggtctcatactacctgcacactatcgaccgcaccatacttgaaaactat
ttttctagtctgaaaaacccaaaactcagggaggaacaggaggcagcccggcgccgccag
cagcgcgagagcaagagcaacgcggccacgcccaccaagggtcccgagggcaaggcagcc
ggccctgccgaagtccccatggactctggtgctgaggaagagaaggcgggagcagccacc
gtgaagaagccgtctccctccaaagcccgcaagaagaagctgaacaagaaggggaggaag
atggctggccgcaagcgtgggcgccccaagaagatgagcaccgcgaaccccgagcggaag
cccaagaagagccaaactgcactggatctcctgcacgctcagaccgtgtctcagacagcg
gcctcctcgccccaggatgcctacaggtcccctcacagcccgttctaccagctacctccg
agcgtgcagcggcactcccccaacccgctgctggtggcgcccaccccgcccgcgctgcag
aagctgctagagtccttcagggtccagtacctgcagttcctggcatacacgaagaccccc
cagtataaggccagcctgcaggagctgctgggccaggagaaggagaagaacgcccagctc
ctgggcacggctcagcagctcctcagccactgccaggcccagaaggaggagatcaggagg
ctgttccagcagaaattggatgagctgggtgtgaaggcgctgacctacaacgacctgatt
caagcgcagaaggagatctccgcccataaccagcagctgcgcgagcagtcggagcagctg
gagcaggacaaccgcgcactccgcagtcagagcctgcagctgctcaaggctcgctgcgag
gagctgcagctggactgggccacgctgtccctggagaagctgctgaaggagaagcaggcc
ctgaagagtcagatctcagagaagcagaggcgctgcctggagctgcagatcagcatcgtg
gagctggagaagagccagcggcagcaggagctcctgcagctcaagtcctgcgtgccaccg
gatgacaccccggccctgcacctgcgcgggaagggcgccctgggccgcgagctggagcct
gacgctggtcggctgcatctggagctggactgtgccaagttctcgctgcctcacttgagc
agcatgagcccagagctctccatgaacggccatgctgccagctacgagctctgcagcgca
ctgagccggccctcgcccaagcaggacacgccccagtacctggcctcacccctagaccag
gaggtggtaccctgcacccccagccacggcggccggccacgtgtggagaagctttctggc
ttggctgtgcccgactacaccaggctgtccccagccaagatcgtgctgagacggcacctc
agccaggaccacgcggtgcccggcaggccggctgccagcgagctacacccgagagctgag
cacaccaaggagaatggccttccctaccagagccccagcgtgcccagcagcatgaagctg
agcccccaggacccgcggcccccatcccctgggaccctgcagcttgctggagagaagagc
agtgagaagggcctgagagagcgtgcctacggcagcggtggggagcccatcaccagcctg
cccatcagcatcccgctcagcaccgtgcagccgaacaagctcccggtcagcatccccctg
gccagcgtggtgctgcccagccgtgccgagagggcgagaagcacccctagtcctgtgctg
cagccccgagacccctcgtccacacttgaaaagcatattggtgctaatgcccacagtgct
gggagcaaaagccttgccctggccccggcaggcttctcctatgctggctcggtggccatc
agcgggaccctggcaggcagcccagcctctcttgcccctggagccgagccggccgccttg
gatgagtcctccagctctgggagtctttttgccactgtggggtcccgcagctccacgcca
cagcatcccctgctgctggcacagccccggaactcgcgcccggcctctcccacccaccag
ctttcctccagcccccggcttggtggggctgcccacggcccgctccccgaggccagcaaa
ggggacctgccctccgattccggcttctcagatccggagagcgaggccaagaggaggatc
gtgttcaccatcgccaccggcacgggcggcaccaagcagtcgccttccagcaaacacagc
cccctgacctccagcgcccgcggggactgtgtgccgagccacggccaggacagccgcaag
cgtggccggcggaagcgagcgtcgacggggacgcccagcttgaccgcaggcgtgtcccct
aagcgccgagccctgccgtctgtcgctggccttttcacgcagccttcagggtctcctcta
aacctcaactccatggtcagtaacatcaaccagcccctggagattacagccatctcatcc
cctgagacctccctgaagagctcccctgtgccctaccaggaccacgatcagccccccgtg
ctcaagaaagagcggcccctgagccagaccaatggggcgcactactccccgctcacctcc
gatgaggagccaggctctgaggacgagcccagcagcgcccgaatcgagagaaaaattgca
acaatctccttagaaagcaaatctcccccgaaaaccttggaaaacggtggtggcgtgctg
ggaaggaggcccgcgcccgccggcgagccagtcaatagtagcaagtggaagtccaccttc
tcgccgatctctgacatcggcctggccaaggccgcggacagccccctgcaggccggcccc
actctgagccagagctccctgttcgcgttccggcccgccctggaggagccccccgccgat
gccaagctggctgcccaccccaggaaaggctttcccacctccctgtcaggggccgacgga
ctcagccccagcaccaaccctgcgaacggctgcaccttcggcgggggccttgccgccgag
ctgagttcacacagcttcagtgatggtgcttctctccccaacaagggccccgaggcagct
ggcctgagctccccactgggcttcccctcgcagcgcgccaaggaggcctcggatgccaac
cctttcctgagcaagaggcagctagacggcctggctgggctgaagggcgagggtggccgc
ggcaaggaggtgggggagggaggcctgccgctgtgcggccctgcggacaaaaccccgctg
cccaccggcaaggccgccaaggcccgggaccgtgagctcgacctcaagaacggccacaac
ctcttcatctccgcggccgccgtgcctcccggaggcctcctcagcggccctggcctggcc
ccggcggtgtcctctgcaggtggcgcggggtcctccgcccagacgcaccggcccttcctg
ggcccctttccgccggggccgcagttcgcgctgggccccatggccctgcaggccaacctg
ggctccgtggccggctcctctgtgctgcagtcgctcttcagctctgtgccggctgccgct
ggcctggtgcacgtgtcgtctgctgccaccagactcaccaactcgcacgccatgggcagc
ttttccggggtggcaggcagcacagttggaggtaactag
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