KEGG   Aotus nancymaae (Ma's night monkey): 105709180
Entry
105709180         CDS       T10127                                 
Symbol
MAPK8
Name
(RefSeq) mitogen-activated protein kinase 8 isoform X1
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
anan  Aotus nancymaae (Ma's night monkey)
Pathway
anan01522  Endocrine resistance
anan04010  MAPK signaling pathway
anan04012  ErbB signaling pathway
anan04014  Ras signaling pathway
anan04024  cAMP signaling pathway
anan04068  FoxO signaling pathway
anan04071  Sphingolipid signaling pathway
anan04137  Mitophagy - animal
anan04140  Autophagy - animal
anan04141  Protein processing in endoplasmic reticulum
anan04210  Apoptosis
anan04215  Apoptosis - multiple species
anan04217  Necroptosis
anan04310  Wnt signaling pathway
anan04380  Osteoclast differentiation
anan04510  Focal adhesion
anan04530  Tight junction
anan04620  Toll-like receptor signaling pathway
anan04621  NOD-like receptor signaling pathway
anan04622  RIG-I-like receptor signaling pathway
anan04625  C-type lectin receptor signaling pathway
anan04657  IL-17 signaling pathway
anan04658  Th1 and Th2 cell differentiation
anan04659  Th17 cell differentiation
anan04660  T cell receptor signaling pathway
anan04664  Fc epsilon RI signaling pathway
anan04668  TNF signaling pathway
anan04722  Neurotrophin signaling pathway
anan04723  Retrograde endocannabinoid signaling
anan04728  Dopaminergic synapse
anan04750  Inflammatory mediator regulation of TRP channels
anan04910  Insulin signaling pathway
anan04912  GnRH signaling pathway
anan04914  Progesterone-mediated oocyte maturation
anan04917  Prolactin signaling pathway
anan04920  Adipocytokine signaling pathway
anan04926  Relaxin signaling pathway
anan04930  Type II diabetes mellitus
anan04931  Insulin resistance
anan04932  Non-alcoholic fatty liver disease
anan04933  AGE-RAGE signaling pathway in diabetic complications
anan04935  Growth hormone synthesis, secretion and action
anan04936  Alcoholic liver disease
anan05010  Alzheimer disease
anan05012  Parkinson disease
anan05016  Huntington disease
anan05017  Spinocerebellar ataxia
anan05020  Prion disease
anan05022  Pathways of neurodegeneration - multiple diseases
anan05132  Salmonella infection
anan05133  Pertussis
anan05135  Yersinia infection
anan05142  Chagas disease
anan05145  Toxoplasmosis
anan05152  Tuberculosis
anan05161  Hepatitis B
anan05162  Measles
anan05166  Human T-cell leukemia virus 1 infection
anan05167  Kaposi sarcoma-associated herpesvirus infection
anan05169  Epstein-Barr virus infection
anan05170  Human immunodeficiency virus 1 infection
anan05171  Coronavirus disease - COVID-19
anan05200  Pathways in cancer
anan05208  Chemical carcinogenesis - reactive oxygen species
anan05210  Colorectal cancer
anan05212  Pancreatic cancer
anan05231  Choline metabolism in cancer
anan05415  Diabetic cardiomyopathy
anan05417  Lipid and atherosclerosis
anan05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:anan00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    105709180 (MAPK8)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    105709180 (MAPK8)
   04012 ErbB signaling pathway
    105709180 (MAPK8)
   04014 Ras signaling pathway
    105709180 (MAPK8)
   04310 Wnt signaling pathway
    105709180 (MAPK8)
   04668 TNF signaling pathway
    105709180 (MAPK8)
   04068 FoxO signaling pathway
    105709180 (MAPK8)
   04071 Sphingolipid signaling pathway
    105709180 (MAPK8)
   04024 cAMP signaling pathway
    105709180 (MAPK8)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    105709180 (MAPK8)
   04137 Mitophagy - animal
    105709180 (MAPK8)
  09143 Cell growth and death
   04210 Apoptosis
    105709180 (MAPK8)
   04215 Apoptosis - multiple species
    105709180 (MAPK8)
   04217 Necroptosis
    105709180 (MAPK8)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    105709180 (MAPK8)
   04530 Tight junction
    105709180 (MAPK8)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    105709180 (MAPK8)
   04621 NOD-like receptor signaling pathway
    105709180 (MAPK8)
   04622 RIG-I-like receptor signaling pathway
    105709180 (MAPK8)
   04625 C-type lectin receptor signaling pathway
    105709180 (MAPK8)
   04660 T cell receptor signaling pathway
    105709180 (MAPK8)
   04658 Th1 and Th2 cell differentiation
    105709180 (MAPK8)
   04659 Th17 cell differentiation
    105709180 (MAPK8)
   04657 IL-17 signaling pathway
    105709180 (MAPK8)
   04664 Fc epsilon RI signaling pathway
    105709180 (MAPK8)
  09152 Endocrine system
   04910 Insulin signaling pathway
    105709180 (MAPK8)
   04920 Adipocytokine signaling pathway
    105709180 (MAPK8)
   04912 GnRH signaling pathway
    105709180 (MAPK8)
   04914 Progesterone-mediated oocyte maturation
    105709180 (MAPK8)
   04917 Prolactin signaling pathway
    105709180 (MAPK8)
   04926 Relaxin signaling pathway
    105709180 (MAPK8)
   04935 Growth hormone synthesis, secretion and action
    105709180 (MAPK8)
  09156 Nervous system
   04728 Dopaminergic synapse
    105709180 (MAPK8)
   04723 Retrograde endocannabinoid signaling
    105709180 (MAPK8)
   04722 Neurotrophin signaling pathway
    105709180 (MAPK8)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    105709180 (MAPK8)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    105709180 (MAPK8)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    105709180 (MAPK8)
   05208 Chemical carcinogenesis - reactive oxygen species
    105709180 (MAPK8)
   05231 Choline metabolism in cancer
    105709180 (MAPK8)
  09162 Cancer: specific types
   05210 Colorectal cancer
    105709180 (MAPK8)
   05212 Pancreatic cancer
    105709180 (MAPK8)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    105709180 (MAPK8)
   05170 Human immunodeficiency virus 1 infection
    105709180 (MAPK8)
   05161 Hepatitis B
    105709180 (MAPK8)
   05171 Coronavirus disease - COVID-19
    105709180 (MAPK8)
   05162 Measles
    105709180 (MAPK8)
   05167 Kaposi sarcoma-associated herpesvirus infection
    105709180 (MAPK8)
   05169 Epstein-Barr virus infection
    105709180 (MAPK8)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    105709180 (MAPK8)
   05135 Yersinia infection
    105709180 (MAPK8)
   05133 Pertussis
    105709180 (MAPK8)
   05152 Tuberculosis
    105709180 (MAPK8)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    105709180 (MAPK8)
   05142 Chagas disease
    105709180 (MAPK8)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    105709180 (MAPK8)
   05012 Parkinson disease
    105709180 (MAPK8)
   05016 Huntington disease
    105709180 (MAPK8)
   05017 Spinocerebellar ataxia
    105709180 (MAPK8)
   05020 Prion disease
    105709180 (MAPK8)
   05022 Pathways of neurodegeneration - multiple diseases
    105709180 (MAPK8)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    105709180 (MAPK8)
   05418 Fluid shear stress and atherosclerosis
    105709180 (MAPK8)
   05415 Diabetic cardiomyopathy
    105709180 (MAPK8)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    105709180 (MAPK8)
   04936 Alcoholic liver disease
    105709180 (MAPK8)
   04932 Non-alcoholic fatty liver disease
    105709180 (MAPK8)
   04931 Insulin resistance
    105709180 (MAPK8)
   04933 AGE-RAGE signaling pathway in diabetic complications
    105709180 (MAPK8)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    105709180 (MAPK8)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:anan01001]
    105709180 (MAPK8)
Enzymes [BR:anan01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     105709180 (MAPK8)
Protein kinases [BR:anan01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   105709180 (MAPK8)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo ABC1 RIO1 Kinase-like FTA2 APH DUF530
Other DBs
NCBI-GeneID: 105709180
NCBI-ProteinID: XP_064226189
Ensembl: ENSANAG00000020152
LinkDB
Position
Unknown
AA seq 427 aa
MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP
FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF
MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQ
LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK
MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV
MDLEERTKNGVIRGQPSPLGAAVINGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEASA
GPLGCCR
NT seq 1284 nt   +upstreamnt  +downstreamnt
atgagcagaagcaagcgtgacaacaatttttatagtgtagagattggagattctacattc
acagtgctgaaacggtatcagaatttaaaacctataggctcaggagctcaaggaatagta
tgtgcagcttatgatgccattcttgaaagaaatgttgcaatcaagaagctaagccgacca
tttcagaatcaaactcatgccaagcgggcctacagagagctagttcttatgaaatgtgtt
aatcacaaaaatataattggccttttgaatgttttcacaccacagaaatccctagaagaa
tttcaggatgtttacatagtcatggagctcatggatgcaaatctttgccaagtgattcag
atggagctagatcatgaaagaatgtcctaccttctgtatcagatgctgtgtggaatcaag
caccttcactctgctggaattattcatcgggacttaaagcctagtaatatagtagtaaaa
tccgactgcactttgaagattcttgactttggtctggccaggactgcaggaacaagtttt
atgatgacgccttacgtagtgactcgctactacagagcacctgaggtcatcctcggcatg
ggctacaaggaaaacgttgacatttggtcagttgggtgcatcatgggagaaatgatcaaa
ggtggtgttttgttcccaggtacagatcatattgatcaatggaataaagttattgaacag
cttggaacaccatgtcctgaattcatgaagaaactgcaaccaacagtaaggacttacgtt
gaaaacagacctaaatatgctggatatagtttcgagaaactcttccctgatgtacttttc
ccagctgactcagaacacaacaaacttaaagccagtcaggcaagggatttgttatccaaa
atgctggtaatagatgcatctaaaaggatctctgtagatgaagctctccagcacccgtac
atcaatgtctggtatgatccttctgaagcagaagctccaccaccaaagatacctgacaag
caattagatgaaagggaacacacaatagaagagtggaaagaattgatatataaggaagtt
atggacctggaggagagaaccaagaatggagttatacgggggcagccctctcctttaggt
gcagcagtgatcaatggctctcagcatccatcgtcatcatcgtccgtcaatgatgtatct
tcaatgtcaacagatccgactttggcctcggatacagacagcagtctagaagcatcagct
gggcctctgggctgctgtagatga

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