Aotus nancymaae (Ma's night monkey): 105710740
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Entry
105710740 CDS
T10127
Symbol
NOS3
Name
(RefSeq) nitric oxide synthase 3 isoform X1
KO
K13242
nitric-oxide synthase, endothelial [EC:
1.14.13.39
]
Organism
anan Aotus nancymaae (Ma's night monkey)
Pathway
anan00220
Arginine biosynthesis
anan00330
Arginine and proline metabolism
anan01100
Metabolic pathways
anan04020
Calcium signaling pathway
anan04022
cGMP-PKG signaling pathway
anan04066
HIF-1 signaling pathway
anan04071
Sphingolipid signaling pathway
anan04151
PI3K-Akt signaling pathway
anan04370
VEGF signaling pathway
anan04371
Apelin signaling pathway
anan04611
Platelet activation
anan04915
Estrogen signaling pathway
anan04921
Oxytocin signaling pathway
anan04926
Relaxin signaling pathway
anan04931
Insulin resistance
anan04933
AGE-RAGE signaling pathway in diabetic complications
anan05415
Diabetic cardiomyopathy
anan05417
Lipid and atherosclerosis
anan05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
anan00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
105710740 (NOS3)
00330 Arginine and proline metabolism
105710740 (NOS3)
09130 Environmental Information Processing
09132 Signal transduction
04370 VEGF signaling pathway
105710740 (NOS3)
04371 Apelin signaling pathway
105710740 (NOS3)
04066 HIF-1 signaling pathway
105710740 (NOS3)
04020 Calcium signaling pathway
105710740 (NOS3)
04071 Sphingolipid signaling pathway
105710740 (NOS3)
04022 cGMP-PKG signaling pathway
105710740 (NOS3)
04151 PI3K-Akt signaling pathway
105710740 (NOS3)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
105710740 (NOS3)
09152 Endocrine system
04915 Estrogen signaling pathway
105710740 (NOS3)
04921 Oxytocin signaling pathway
105710740 (NOS3)
04926 Relaxin signaling pathway
105710740 (NOS3)
09160 Human Diseases
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
105710740 (NOS3)
05418 Fluid shear stress and atherosclerosis
105710740 (NOS3)
05415 Diabetic cardiomyopathy
105710740 (NOS3)
09167 Endocrine and metabolic disease
04931 Insulin resistance
105710740 (NOS3)
04933 AGE-RAGE signaling pathway in diabetic complications
105710740 (NOS3)
Enzymes [BR:
anan01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
105710740 (NOS3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
Motif
Other DBs
NCBI-GeneID:
105710740
NCBI-ProteinID:
XP_021520893
Ensembl:
ENSANAG00000036230
LinkDB
All DBs
Position
Unknown
AA seq
1203 aa
AA seq
DB search
MGNLKSVAQESGPPCGLGLGLGLGLCGKQSPATPAPEPSRAPASPPPPAPEHSPPSSPLT
QPPEGPRFPRVKNWEVGSIAYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSPGPTAP
EQLLSQARAFINQYYSSIKRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWRN
APRCVGRIQWGKLQVFDARDCRSAQEMFTYICNHIKYATNRGNLRSAITVFPQRCPGRGD
FRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCVQHGWTPGSGRFDVLPLLLQAPDEPP
ELFLLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMST
EIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSYQLAKVTIVDH
HAATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPW
KGSAAKGTGITRKKTFKEVANAVKISASLMGTVMAKRVKATILFGSETGRAQGYAQQLGR
LFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGESFAAALMEMSGPYNSS
PRPEQHKSYKIRFNSVSCSDPLVSSWRRRRKESSNTDSAGALGTLRFCVFGLGSRAYPHF
CAFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAQAAFQAACETFCVGEDAKAAA
RDIFSPKRSWKRQRYRLSAQTEGLQLLPGLIHVHRRKMFQATILSVENLQSSKSTRATIL
VRLDTGGQEGLQYQPGDHIGVCPPNRPGLVEALLSRVEDPPAPTEPVAVEQLEKGSPGGP
PPGWVRDPRLPPCTLRQALTFFLDITSPPSPQLLRLLSTLAEEPREQQELEALSQDPRRY
EEWKWFRCPTLLEVLEQFPSVAPPAPLLLTQLPLLQPRYYSVSSAPSIHPGEIHLTVAVL
AYRTQDGLGPLHYGVCSTWLSQLKPGDPVPCFIRGAPSFRLPPDPSLPCILVGPGTGIAP
FRGFWQERLHDIESKGLQPAPMTLVFGCRCSQLDHLYRDEVQDAQQRGVFGRVLTAFSRE
PDNPKTYVQDILRTELAAEVHRVLCLERGHMFVCGDVTMATNVLQTVQRILATEGDMELD
EAGDVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERQLRGAVPWAFDPPASDT
NGP
NT seq
3612 nt
NT seq
+upstream
nt +downstream
nt
atgggcaacttgaagagcgtggcccaggagtctgggccaccttgcggcctggggctgggg
ctgggcctcgggctgtgcggcaagcagagcccagccaccccagcccctgagcccagccga
gccccagcatcccctcccccgccagcgccagaacacagccccccgagctccccgctaacc
cagccaccggaggggcccaggttccctcgagtgaagaactgggaggtggggagcatcgcc
tatgataccctcagcgcccaggcacagcaggatgggccctgcaccccaagacgctgcctg
ggctccctggtatttccaaggaaactgcagggccggccctcccccggccccacagcccct
gagcagctgctgagtcaggcccgggccttcatcaaccagtactacagctccatcaagagg
agcggctcccaggcccacgagcagcggcttcaggaggtggaagccgaggtggcagccaca
ggcacctaccagcttagggagagcgagctggtgttcggggccaagcaggcctggcgcaac
gctccccgctgtgtgggccggatccagtgggggaagctgcaggtgttcgatgcccgggac
tgcaggtctgcacaggagatgttcacctacatctgcaaccacatcaagtatgccaccaac
cggggcaaccttcgctcggccatcacagtgttcccgcagcgctgccctggccgcggagac
ttccgaatctggaacagccagctggtgcgctacgcgggctaccggcagcaggatggctct
gtgcggggggacccggccaacgtggagatcactgagctctgcgtccagcacggctggacc
ccaggaagcggccgcttcgacgtgctgcccctgctgctgcaggccccagacgagccccca
gaactcttccttctgccccctgagctggtccttgaggtgcccctggagcaccccacgctg
gagtggttcgcagccctgggcctgcgctggtacgccctcccggcggtgtccaacatgctg
ctggaaattgggggtctggagttccccgcagcccccttcagtggctggtacatgagcact
gagattggcaccaggaacctgtgtgacccccaccgctacaacatcctggaggacgtggct
gtctgcatggacctggatacccggacgacctcgtccctgtggaaggacaaggcagcggta
gaaatcaacttggctgtgctgcacagttaccagctggccaaagtgaccatcgtggaccac
cacgctgccacagcctccttcatgaagcacctggagaatgagcagaaggccagggggggc
tgccctgcagactgggcctggatcgtgccccccatctcaggcagcctcactcctgtcttc
catcaggagatggtcaactatttcctgtcccctgccttccgctaccagccagacccctgg
aaggggagtgcggccaagggcaccggcatcaccaggaagaagacctttaaggaagtggcc
aacgctgtgaagatctccgcctcgctcatgggcaccgtgatggcgaagcgagtgaaggca
acaatcctgtttggctctgagaccggccgggcccagggctacgcacagcagttggggaga
ctcttccggaaggcttttgacccccgggtcctgtgtatggatgagtatgacgtggtgtcc
ctcgaacacgagacgctggtgctggtggtaaccagcacatttgggaatggggatcccccg
gagaatggagagagctttgcagccgccctgatggagatgtccggcccctacaacagctcc
ccaaggccggagcagcacaagagttataagatccgcttcaacagcgtctcctgctcagac
ccactggtgtcctcgtggcggcggaggaggaaggagtccagtaacacagacagtgcaggg
gccctgggcaccctcaggttctgtgtgttcgggctgggctcccgggcgtacccccacttc
tgcgcctttgctcgagcggtggacacgcggctggaggaactgggcggggagcggctgctg
cagctgggccagggcgacgagctgtgtggccaggaggaggccttccgaggctgggcccag
gccgccttccaggccgcctgtgagactttctgtgtgggagaggatgccaaagctgccgcc
cgagacatcttcagccccaaacggagctggaagcgccagaggtaccggctgagcgcccag
accgagggcctgcagttgctgccaggtctgatccacgtgcacaggcggaagatgttccag
gctacaatcctttcagtggaaaacctgcaaagcagcaagtccacgcgggccaccatcctg
gtgcgcctggacactggaggccaggaggggctgcagtaccagccgggggaccacataggc
gtctgcccacccaaccggcccggccttgtggaggcactgctgagccgcgtggaggacccg
ccggcaccaactgagcctgtggcagtagagcagctggagaagggcagccctggtggccct
ccccccggctgggtgcgggacccccggctgcccccgtgcacactgcgccaggctctcacc
ttcttcctggacatcacctccccacccagtcctcagctcttgcggctgctcagcaccctg
gcagaagagcccagggaacagcaggagctggaggccctcagccaggatccccggcgctac
gaggagtggaagtggttccgctgccccacgctgctggaggtgctggagcagttcccgtcg
gtggccccgcctgccccactgctcctcacccagctgcctctgctgcagccccggtactac
tcagtcagctcagcacccagcatccaccccggagagatccacctcaccgtagctgtgctg
gcatacaggacccaggatgggctgggccccctgcactatggagtctgctccacgtggcta
agccaactcaagcctggagaccctgtgccctgcttcatccggggggctccctccttccgg
ctgccgcccgatcccagcctgccctgcatcctggtgggcccaggcactggcattgccccc
ttccggggattctggcaggagcggctgcacgacattgagagcaaagggctgcagcccgcc
cccatgactttggtgttcggctgccgatgctcccaacttgaccatctctaccgcgacgag
gtgcaggacgcccagcagcgcggggtgtttggccgagtcctcaccgccttctcccgggaa
cccgataatcccaagacctacgtgcaggacatcctaaggacggagctggctgcggaggtg
caccgcgtgctgtgcctcgagcggggccacatgtttgtctgcggcgatgtcaccatggca
accaacgtcctgcagaccgtgcagcgcatcctggcgaccgagggcgacatggagctggac
gaggccggcgacgtcatcggcgtgctgcgggatcagcaacgctaccacgaagacattttt
gggctcacgctgcgcacccaggaggtgacaagccgcatacgcacccagagtttttccttg
caggagcggcagttgcggggcgcagtgccctgggcgttcgacccgcccgcctcagacacc
aatggcccctga
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integrated database retrieval system