Aotus nancymaae (Ma's night monkey): 105713468
Help
Entry
105713468 CDS
T10127
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3 isoform X1
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
anan Aotus nancymaae (Ma's night monkey)
Pathway
anan00230
Purine metabolism
anan00670
One carbon pool by folate
anan01100
Metabolic pathways
anan01523
Antifolate resistance
Module
anan_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
anan00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
105713468 (GART)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
105713468 (GART)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
105713468 (GART)
Enzymes [BR:
anan01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
105713468 (GART)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
105713468 (GART)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
105713468 (GART)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
ATP-grasp
CPSase_L_D2
ATP-grasp_2
ATP-grasp_4
ATP-grasp_3
Dala_Dala_lig_C
RimK
Sacchrp_dh_NADP
SNF5
LUD_dom
ATP-grasp_5
Motif
Other DBs
NCBI-GeneID:
105713468
NCBI-ProteinID:
XP_021525126
Ensembl:
ENSANAG00000000266
LinkDB
All DBs
Position
Unknown
AA seq
1010 aa
AA seq
DB search
MAARILVIGSGGREHTLAWKLAQSNHVKHVLVAPGNAGTACSEKISNTAVSISDHTALAQ
FCKDEKIEFVVVGPEAPLAAGIVGNLMSAGVRCFGPTAEAAQLESSKRFAKEFMDRHGIP
TAQWKAFTKPEEACSFIMSADFPALVVKASGLAAGKGVIVAKTKEEACKAVQEIMQEKAF
GVAGETIVIEELLDGEEVSCLCFTDGKTVAPMPPAQDHKRLLEGDGGPNTGGMGAYCPAP
QVSSDLLLKIKNTVLQRTVDGMQQEGTPYTGILYAGIMLTKDGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIRSTLDGLLCTSLPVWLENHTALTVVMASKGYPGDYTKGVEITGFPEA
QAQGLEVFHAGTALKNGKVVTHGGRVLAVTAIRENLISALEEAKKGLAAIKFEGAIYRKD
IGFRAIAFLQQPRGLTYKESGVDIVAGNTLVKKIQPLAKATSRSGCKVDLGGFAGLFDLK
AAGFKDPLLASGTDGVGTKLKIAQLCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDLNVTEAVIAGIAKACGKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
HLEIITEGDVVVGIASSGLHSNGFSLVRKIVAKSSLQYSSPAPDGCGDQTLGELLLTPTR
IYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPEKFGVDLDAQTWRIPKVFSWLQQEG
HLSEEEMARTFNCGVGAALVVSKEQTEQILGDIQQQKEEAWVIGSVVARAEGSPRVKVKN
LIENMQINGSVLKNGSLKNYLSVEQKKARVAVLISGTGSNLQALIDSTREPNSSAQIDVV
ISNKAAVAGLDKAERAGIPTRVINHKLYKNRVEFDNAIDLVLEEFSIDIVCLAGFMRILS
GPFVRKWNGKMLNIHPSLLPSFKGSNAHEQALETGVTVTGCTVHFVAEDVDAGQIILQEA
VPVKRGDTVTTLSERVKLAEHKIFPAALQLVASGTVQLGENGKICWVKEE
NT seq
3033 nt
NT seq
+upstream
nt +downstream
nt
atggcagcccgaatacttgtaattggcagtggaggaagggaacatacgctggcctggaaa
cttgcacagtctaatcatgtcaaacacgtattggttgccccaggaaatgcaggcactgcc
tgctctgaaaagatttcaaataccgctgtctcaatcagtgaccacactgcccttgctcaa
ttctgcaaagatgagaaaattgaatttgtagttgttggaccagaagcacctctggctgct
gggattgttgggaacctgatgtctgcaggagtgcgatgctttggaccaacagcagaagcg
gctcagttagagtccagcaaaagatttgccaaagagtttatggacagacatggaatccca
actgcacaatggaaggctttcacaaaacctgaagaggcctgcagcttcattatgagtgca
gacttccctgctttggttgtgaaggccagtggccttgcggctggaaaaggggtgattgtt
gcaaagaccaaagaagaggcctgcaaagctgtacaggagatcatgcaggagaaggccttt
ggggtagctggagaaacaattgtcattgaagaacttcttgacggagaagaggtgtcttgt
ctatgtttcactgatggcaagactgtggcccccatgcccccagcacaggaccataagcga
ttactggagggagatggcggccctaacacagggggaatgggagcatattgtccggcacct
caggtttctagtgatctactactaaaaattaaaaatactgttcttcagaggacagtggat
ggcatgcagcaagagggtactccatatacaggtattctctatgctggaataatgctgacc
aaggatggcccaaaagttctagagtttaattgccgttttggtgatccagagtgccaagta
atcctcccacttcttaaaagtgatctttatgaagtgattcggtccaccttagatggcctg
ctctgcacatctctgcctgtttggctagaaaaccacactgccctaactgtcgtcatggca
agtaaaggttatcctggagactacaccaagggtgtagagataacaggatttcctgaggct
caagctcaaggtctggaggtgttccacgcaggcactgccctcaaaaatggcaaagtagta
actcacgggggtagagttcttgcagtcacagccatccgggaaaatctcatatcagccctc
gaggaagccaagaaaggactagctgctataaagtttgagggagcaatttataggaaagac
attggctttcgtgccatagctttcctccagcagcccaggggcttgacttacaaggaatct
ggagtagacattgtagctggaaatacgctggtcaagaaaattcagcctttagcaaaagct
acttccagatcaggctgtaaagttgatcttggaggttttgctggtctttttgatttaaaa
gcagctggtttcaaggatccccttctggcctctggaacagatggcgttggaactaaacta
aagattgcccagctgtgcaataaacatgacaccattggtcaagatttggtagcaatgtgt
gtgaatgatattctggcacaaggagcagagcccctcttcttccttgattacttttcctgt
ggaaaacttgacctcaatgtaactgaagctgttattgctggaattgctaaagcctgtgga
aaagctggatgtgctctccttggaggtgaaacagcagaaatgcctgacatgtatccccct
ggagagtatgacctagctggatttgctgttggtgccatggagcgagatcagaaactccct
cacctggaaataatcactgagggtgatgttgttgttggaatagcttcatctggtcttcat
agcaatggatttagccttgtgaggaaaatcgtggcaaaatcttcccttcagtactcctct
ccagcacctgatggttgtggtgaccagactttaggggagttacttctcacaccaaccaga
atctacagccattcactgttacctgtcttacgttcaggacatgtcaaagcctttgcccat
attactggtggaggattactagagaacatccccagagtcctgcctgagaaatttggggta
gatttagatgctcagacctggaggatccccaaggtcttctcttggttacagcaggaagga
cacctctctgaggaagagatggctagaacatttaactgtggggttggtgctgcccttgtg
gtatcaaaggagcagacagagcagattctgggggatatccagcagcaaaaggaagaagcc
tgggtgattggcagcgtggttgcacgagctgaaggttccccccgtgtgaaagtcaagaat
ctgattgaaaacatgcaaataaatgggtcagtgttgaagaatggttccctgaaaaattat
ttatctgtcgaacaaaaaaaggccagggtggctgtcttaatatctggaacaggatcgaac
ctgcaagcactcatagacagtactcgggaaccaaatagctctgcacaaattgatgttgtt
atctccaacaaagccgcagtggctgggctagataaagcagaaagagctggtattcccacc
agagtaattaatcataaactgtataaaaatcgtgtagaatttgacaatgcaattgaccta
gtccttgaagagttctccatagacatagtctgtcttgcaggattcatgagaattctttct
ggcccctttgtcagaaagtggaatggaaaaatgctcaatatccacccatccttgctccct
tcttttaagggttcaaatgcccatgagcaagccctggaaaccggagtcacagttactggg
tgcactgtacactttgtagctgaagatgtagatgctggacaaattattttgcaagaagct
gttcctgtgaagaggggtgacacggtcacaactctttctgaaagagtaaaattagcagaa
cacaaaatattccctgcagccctccagctggtggccagtggaactgtgcagcttggagaa
aatggcaagatctgttgggttaaagaggaatga
DBGET
integrated database retrieval system
