Aotus nancymaae (Ma's night monkey): 105717028
Help
Entry
105717028 CDS
T10127
Symbol
ERBB2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2 isoform X1
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
anan Aotus nancymaae (Ma's night monkey)
Pathway
anan01521
EGFR tyrosine kinase inhibitor resistance
anan01522
Endocrine resistance
anan01524
Platinum drug resistance
anan04010
MAPK signaling pathway
anan04012
ErbB signaling pathway
anan04020
Calcium signaling pathway
anan04066
HIF-1 signaling pathway
anan04151
PI3K-Akt signaling pathway
anan04510
Focal adhesion
anan04518
Integrin signaling
anan04519
Cadherin signaling
anan04520
Adherens junction
anan04530
Tight junction
anan05200
Pathways in cancer
anan05205
Proteoglycans in cancer
anan05206
MicroRNAs in cancer
anan05212
Pancreatic cancer
anan05213
Endometrial cancer
anan05215
Prostate cancer
anan05219
Bladder cancer
anan05223
Non-small cell lung cancer
anan05224
Breast cancer
anan05226
Gastric cancer
anan05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
anan00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
105717028 (ERBB2)
04012 ErbB signaling pathway
105717028 (ERBB2)
04066 HIF-1 signaling pathway
105717028 (ERBB2)
04020 Calcium signaling pathway
105717028 (ERBB2)
04151 PI3K-Akt signaling pathway
105717028 (ERBB2)
09133 Signaling molecules and interaction
04518 Integrin signaling
105717028 (ERBB2)
04519 Cadherin signaling
105717028 (ERBB2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
105717028 (ERBB2)
04520 Adherens junction
105717028 (ERBB2)
04530 Tight junction
105717028 (ERBB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
105717028 (ERBB2)
05206 MicroRNAs in cancer
105717028 (ERBB2)
05205 Proteoglycans in cancer
105717028 (ERBB2)
05230 Central carbon metabolism in cancer
105717028 (ERBB2)
09162 Cancer: specific types
05212 Pancreatic cancer
105717028 (ERBB2)
05226 Gastric cancer
105717028 (ERBB2)
05219 Bladder cancer
105717028 (ERBB2)
05215 Prostate cancer
105717028 (ERBB2)
05213 Endometrial cancer
105717028 (ERBB2)
05224 Breast cancer
105717028 (ERBB2)
05223 Non-small cell lung cancer
105717028 (ERBB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
105717028 (ERBB2)
01524 Platinum drug resistance
105717028 (ERBB2)
01522 Endocrine resistance
105717028 (ERBB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
anan01001
]
105717028 (ERBB2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
anan04147
]
105717028 (ERBB2)
04090 CD molecules [BR:
anan04090
]
105717028 (ERBB2)
Enzymes [BR:
anan01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
105717028 (ERBB2)
Protein kinases [BR:
anan01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
105717028 (ERBB2)
Exosome [BR:
anan04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
105717028 (ERBB2)
CD molecules [BR:
anan04090
]
Proteins
105717028 (ERBB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
ABC1
Haspin_kinase
Kinase-like
Motif
Other DBs
NCBI-GeneID:
105717028
NCBI-ProteinID:
XP_012307392
Ensembl:
ENSANAG00000025053
UniProt:
A0A2K5D0F9
LinkDB
All DBs
Position
Unknown
AA seq
1255 aa
AA seq
DB search
MELAAWCRWGLLLALLPPGAAGTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNL
ELTYLPTNASLSFLQDIQEVQGYVLIAHNQVRQVPLQRLRIVRGTQLFEDNYALAVLDNG
DPPDNTTPVTGASPGGLRELQLRSLTEILKGGVWIQRNPQLCYQDTILWKDIFHKNNQLA
LTLIDTNRSRACHPCSPACKGSRCWGESSEDCQSLTRTVCAGGCARCKGPLPTDCCHEQC
AAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTACP
YNYLSTDVGSCTLVCPMHNQEVTAEDGTQRCEKCSKPCARVCYGLGMEHLREARAVTSAN
IQEFAGCKKIFGSLAFLPESFDGDPASNTVPLQPEQLQVFETLEEITGYLYISAWPDSLP
DLSVFQNLQVIRGRILHNGAYSLTLQGLGISWLGLRSLRELGSGLALIHHNARLCFVHTV
PWDNLFRNPHQALLHTANRPEHECVGKDLACHPLCARGHCWGPGPTQCVNCSQFLRGQEC
VEECRVLQGLPREYVNARHCLPCHPECQPQNGSVTCSGPEADQCVACAHYKDSPFCVARC
PSGVKPDLSYMPIWKFPDEEGTCQPCPINCTHSCVDLDDKGCPAEQRASPLTSIISAVVG
ILLVMVLGLLLGILIKRRQQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETEL
RKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSP
YVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVR
LVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFT
HQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWM
IDSECRPRFRELVSEFSRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLEDDDMGDLVDA
EEYLVPQQGFFCPDPVPGAGGMAHRRHRSSSTRSGGGDLTLGLEPSEEEAPRSPLAPSEG
AGSDVFDGDLGMGAAKGLQSLPPHDPSPLQRYSEDPTVPLPSETDGYVAPLTCSPQPEYV
NQPDVRPQPSSPREGPLPPARPAGATLERPKTLSPGKNGVVKDVFAFGSAVENPEYLAPR
GGAAPQPHPPPAFSPAFDNLYYWDQDPSERGAPPSTFEGTPTAENPEYLGLDVPV
NT seq
3768 nt
NT seq
+upstream
nt +downstream
nt
atggagctggcggcctggtgccgctgggggctccttctcgccctcttgccccccggagcc
gcgggcacccaagtgtgcaccggcacagacatgaagctgcggctccctgccagtcccgag
acccacctggacatgctccgccacctctaccagggctgccaggtggtgcagggtaacctg
gaactcacctacctgcccaccaatgccagcctctccttcctgcaggatatacaggaggtg
cagggctacgtgctcatcgcccacaaccaagtgagacaggtcccgctgcagaggctgcgg
attgtacgaggcacccagctctttgaggacaactatgccctggctgtgctagacaacgga
gaccctccggacaataccacacctgtcacaggggcctccccaggaggcctgcgggagctg
cagcttcgaagcctcacagagatcttgaagggaggggtctggatccagcggaacccccag
ctctgctaccaggacacgattttgtggaaggacatcttccacaagaacaaccagctggct
ctcacgctgatagacaccaaccgctctcgggcctgccacccctgttctccggcatgtaag
ggctcccgctgctggggagagagttctgaggactgtcagagcctgacacgcactgtctgt
gccggtggctgtgcccgctgcaagggcccactgcccactgactgctgccatgagcagtgt
gctgctggctgcacgggccccaagcactccgactgcctggcctgcctccacttcaaccac
agtggcatctgtgagctgcactgcccagccctggtcacctacaacacagacacctttgag
tccatgcccaaccccgagggccggtatacatttggtgccagctgtgtgactgcctgtccc
tacaattacctatcaacggacgtgggatcctgcacgcttgtctgccccatgcacaaccaa
gaggtgacagcggaggacggaacacagcgatgtgagaagtgcagcaagccctgtgcccga
gtgtgctatggtctgggcatggagcacttgcgagaggcgagggcggtcaccagtgccaat
atccaggagtttgctggctgcaagaagatctttgggagcctggcatttctgccggagagc
tttgatggggacccagcctccaacaccgtccccctacagccagagcagctccaagtgttt
gagactctggaagagatcacaggttacctgtatatctcagcatggccagacagcctgcct
gacctcagcgtcttccagaacctgcaagtaatccgaggacgaattctgcacaatggtgcc
tactcgctgaccctgcaagggctgggcatcagctggctggggctgcgctcactgcgggaa
ctgggcagtggactggccctcatccaccacaatgcccgcctctgcttcgtgcacacggtg
ccctgggacaatctcttccggaacccgcaccaagccctgctccacactgccaaccggcca
gagcacgagtgtgtgggcaaggacctggcctgccacccgctgtgcgcccgagggcactgc
tggggtccggggcccacccagtgtgtcaactgtagccagttccttaggggccaggagtgc
gtggaggaatgccgagtactgcaggggctccctagggagtatgtgaatgccagacactgt
ttgccgtgccaccctgagtgtcagccccagaatggctcagtgacctgttctggaccggag
gctgaccagtgtgtggcctgtgcccactacaaggactctcctttctgcgtggcccgctgc
cccagcggtgtgaaacctgacctctcctacatgcccatctggaagtttccagatgaggag
ggcacatgccagccttgccccatcaactgcacccactcctgtgtggacctggatgacaag
ggctgccctgccgagcagagagccagccctctgacgtccatcatctctgcggtggtgggc
attctgctggtcatggtcttggggctgctccttgggatcctcatcaagcgacggcagcag
aagatccggaagtacacgatgcgaaggctgctgcaggaaacggagctggtagagccgctg
acaccgagcggagccatgcccaaccaggcacagatgcggatcctgaaagagactgagctg
aggaaggtgaaggtgcttggatccggagcttttggcacagtctacaagggaatctggatc
cctgatggggagaatgtgaaaattccagtggccatcaaagtgttgagagaaaacacatcc
cctaaagccaacaaagaaatcttagacgaagcatacgtgatggctggtgtgggctcccca
tatgtctcccgcctcctgggcatctgcctgacatccacagtgcaactggtgacgcagctt
atgccctatggctgcctcttagaccacgtccgggaacaccgaggacgcctgggctcccag
gacctgctgaactggtgtgtgcagattgccaaggggatgagctacctggaggatgtgcgg
ctcgtacacagggacttggctgctcggaacgtgctggtcaagagtcccaaccacgtcaag
attacagactttgggctagctcggctgctggacattgatgagacagaataccacgcagat
gggggcaaggtgcccatcaagtggatggcattggagtccattctccgccggcggttcacc
caccagagtgacgtatggagttacggtgtcactgtgtgggagctgatgacttttggggcc
aaaccttacgatgggatcccagcccgggagatccctgacctgctggagaagggggagcgg
ctgccccagccccctatctgcaccattgatgtctacatgatcatggtcaaatgttggatg
attgactctgaatgtcggccaagattccgggagttggtgtctgaattctcccgaatggcc
agggacccgcagcgctttgtggtcatccagaatgaggacttgggcccagccagtcccttg
gatagcaccttctaccgctcactgctggaggacgatgacatgggggacctggtggatgct
gaggagtatctggtgccccagcagggcttcttctgcccagaccctgtcccaggtgctgga
ggcatggcccaccgcaggcaccgcagctcatccactaggagtggcggtggggacctgacg
ctagggctggagccctctgaagaggaggcccccaggtctccattggcaccctccgaaggg
gctggctccgatgtatttgatggtgacctgggaatgggagcagccaaagggttgcaaagc
ctccccccacatgaccccagccctctacagcggtacagtgaggaccccacagtacccctg
ccctctgagactgatggctacgttgcccccctgacctgcagcccccagcctgaatatgtg
aaccagccagatgttcggccacagccctcttcgccccgagagggtcctctgcctcctgcc
cgacctgctggtgccactctggaaaggcccaagactctctccccagggaagaatggggtc
gtcaaagatgtttttgcctttgggagtgccgtggagaaccccgagtacttggcaccccgg
ggaggagctgcccctcagccccaccctcctcctgccttcagcccagccttcgacaacctc
tattactgggaccaggacccatcagagcggggggctccacccagcaccttcgaagggacc
cctacagcagagaacccagagtacctgggtctcgatgtgccagtgtga
DBGET
integrated database retrieval system
