Aotus nancymaae (Ma's night monkey): 105721171
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Entry
105721171 CDS
T10127
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
anan Aotus nancymaae (Ma's night monkey)
Pathway
anan00790
Folate biosynthesis
anan01100
Metabolic pathways
anan01240
Biosynthesis of cofactors
anan01523
Antifolate resistance
anan04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
anan00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
105721171 (FPGS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
105721171 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
105721171 (FPGS)
Enzymes [BR:
anan01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
105721171 (FPGS)
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Ortholog
Paralog
GFIT
Motif
Pfam:
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
105721171
NCBI-ProteinID:
XP_012313513
Ensembl:
ENSANAG00000038490
UniProt:
A0A2K5FAB5
LinkDB
All DBs
Position
Unknown
AA seq
586 aa
AA seq
DB search
MSPVWSHLRAALFLAAASARGVTTQVAAQRGLSAWPVPQEPSMEYQDAVRMLNTLQTNAS
YLEQAKRQRGDPQTQLEAMELYLARSGLQVEDLDRLNIIHVTGTKGKGSTCAFTECILRS
YGLKTGFFSSPHLVQVRERIRINGQPISPDLFTKYFWRLYHRLEETKDGSCVSMPPYFRF
LTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGVSSLGIDHTSLLGDTVEKIA
WQKGGIFKQGVPAFTVLQPEGPLAVLRDRAQQISCPLYLCPPLEALEEGGLPLTLGLEGE
HQRSNAALALQLAHCWLQWQDHHDAGELKESRPGLLWQLPLAPVFQPTSHMRLGLRNTEW
LGRTQVLRRGPLTWYLDGAHTPSSVQACVRWFCQALQGRERLSSGTEVRVLLFNTTGDRD
SAVLLKLLQPCQFNYAVFCPNLTEVSSTGNADQQNFTVTLDQVLLRCLEHQQHWNCLDEE
QASPALWSAPSPELAGPASLLLAPHPPHSSASSLVFSCISHALQWISQGRDPVFQPPSSP
KSLLTHPVARSGASVLHEAAAVHVLVTGSLHLVGGVLKLLEPALSQ
NT seq
1761 nt
NT seq
+upstream
nt +downstream
nt
atgtcgccggtgtggagccacctgcgcgctgctctgtttctggcagcggcttctgcgcgc
ggcgtaacgacccaggtcgcggcgcagcggggcttgagcgcgtggccggtgccacaggag
cccagcatggagtaccaggatgccgtgcgcatgctcaataccctgcagaccaatgccagc
tatctggagcaggcaaagcgccagaggggtgacccccagacacagctggaagccatggaa
ctgtacctggcacgaagtgggctgcaggtggaggacctggaccggctgaacatcatccac
gtcactgggacgaaggggaagggttccacctgtgccttcactgaatgtatcctccgaagc
tatggcctgaagacgggattctttagctctccccacctggtgcaggttcgggagcggatc
cgcatcaatgggcagcccatcagtcctgacctcttcaccaagtacttctggcgcctctac
caccggctggaggagaccaaggacggcagctgtgtctccatgcccccctacttccgcttc
ctgacactcatggccttccacgtcttcctccaagagaaggtggacctggcagtggtggag
gtgggcattggcggggcttatgactgcaccaacatcatcaggaagcctgtggtgtgcgga
gtctcctctcttggcatcgaccacaccagcctcctgggggacacggtggagaagatcgca
tggcagaaagggggcatctttaagcaaggtgtccctgctttcactgtgctgcagcctgaa
ggtcccctggcagtgctgagggaccgagctcagcagatctcatgtcctctctacctgtgt
cccccgctggaggccctggaggaaggggggctgccgctgaccttgggcctggagggggag
caccagcggtccaatgccgccttggctttgcagctggcccactgctggctgcagtggcag
gaccaccatgatgctggggagctgaaggaatccaggccaggcctcctgtggcagctgccc
ctggcacccgtgttccagcccacatcccacatgcggcttgggcttcgaaacacggagtgg
ctgggccggacgcaggtgctgcggcgcgggcccctcacctggtacctggacggcgcacac
acccctagcagcgtgcaggcctgcgtccgttggttctgccaggcgctgcagggccgcgag
aggctgagcagtgggaccgaggttcgagtcttgctcttcaataccactggggaccgggac
tcggcggtcctactgaagctgctgcagccctgccagttcaactatgccgtcttctgcccc
aacctgacagaggtgtcatccacaggcaacgcagaccaacagaacttcacggtgacactg
gaccaagtgttgctccgctgcctggaacaccagcagcactggaactgcctggacgaggag
caggccagcccggccctctggagtgcccccagcccggagcttgctgggcctgcatccttg
ctgctggcgccccacccaccccacagcagtgccagctcccttgtcttcagctgcatttca
catgccttgcaatggatcagccaaggtcgagaccccgtcttccagccacccagttcccca
aagagcctcctcacccaccctgtggcacgcagtggggctagcgtactccatgaggctgct
gccgtccacgtgctggtcactggcagcctgcacctggtgggtggtgtcctgaagctgcta
gagcctgcactgtcccagtaa
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