KEGG   Aotus nancymaae (Ma's night monkey): 105722415
Entry
105722415         CDS       T10127                                 
Symbol
PRKAA1
Name
(RefSeq) 5'-AMP-activated protein kinase catalytic subunit alpha-1 isoform X1
  KO
K07198  5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
Organism
anan  Aotus nancymaae (Ma's night monkey)
Pathway
anan04068  FoxO signaling pathway
anan04140  Autophagy - animal
anan04150  mTOR signaling pathway
anan04151  PI3K-Akt signaling pathway
anan04152  AMPK signaling pathway
anan04211  Longevity regulating pathway
anan04213  Longevity regulating pathway - multiple species
anan04371  Apelin signaling pathway
anan04530  Tight junction
anan04710  Circadian rhythm
anan04714  Thermogenesis
anan04910  Insulin signaling pathway
anan04920  Adipocytokine signaling pathway
anan04921  Oxytocin signaling pathway
anan04922  Glucagon signaling pathway
anan04931  Insulin resistance
anan04932  Non-alcoholic fatty liver disease
anan04936  Alcoholic liver disease
anan05410  Hypertrophic cardiomyopathy
anan05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:anan00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    105722415 (PRKAA1)
   04068 FoxO signaling pathway
    105722415 (PRKAA1)
   04151 PI3K-Akt signaling pathway
    105722415 (PRKAA1)
   04152 AMPK signaling pathway
    105722415 (PRKAA1)
   04150 mTOR signaling pathway
    105722415 (PRKAA1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    105722415 (PRKAA1)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    105722415 (PRKAA1)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    105722415 (PRKAA1)
   04922 Glucagon signaling pathway
    105722415 (PRKAA1)
   04920 Adipocytokine signaling pathway
    105722415 (PRKAA1)
   04921 Oxytocin signaling pathway
    105722415 (PRKAA1)
  09149 Aging
   04211 Longevity regulating pathway
    105722415 (PRKAA1)
   04213 Longevity regulating pathway - multiple species
    105722415 (PRKAA1)
  09159 Environmental adaptation
   04710 Circadian rhythm
    105722415 (PRKAA1)
   04714 Thermogenesis
    105722415 (PRKAA1)
 09160 Human Diseases
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    105722415 (PRKAA1)
   05410 Hypertrophic cardiomyopathy
    105722415 (PRKAA1)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    105722415 (PRKAA1)
   04932 Non-alcoholic fatty liver disease
    105722415 (PRKAA1)
   04931 Insulin resistance
    105722415 (PRKAA1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:anan01001]
    105722415 (PRKAA1)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:anan04131]
    105722415 (PRKAA1)
   03029 Mitochondrial biogenesis [BR:anan03029]
    105722415 (PRKAA1)
Enzymes [BR:anan01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.31  [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase
     105722415 (PRKAA1)
Protein kinases [BR:anan01001]
 Serine/threonine kinases: CAMK group
  CAMKL family
   105722415 (PRKAA1)
Membrane trafficking [BR:anan04131]
 Autophagy
  Other autophagy associated proteins
   Others
    105722415 (PRKAA1)
Mitochondrial biogenesis [BR:anan03029]
 Mitochondrial quality control factors
  Regulator of mitochondrial biogenesis
   Other regulator of mitochondrial biogenesis
    105722415 (PRKAA1)
  Mitophagy factors
   Other mitophagy factors
    105722415 (PRKAA1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr AMPK_alpha_AID AdenylateSensor ABC1 Kinase-like Kdo APH
Other DBs
NCBI-GeneID: 105722415
NCBI-ProteinID: XP_021527527
Ensembl: ENSANAG00000032687
UniProt: A0A2K5E9M7
LinkDB
Position
Unknown
AA seq 559 aa
MRRLSSWRKMATAEKQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNR
QKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNG
RLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEF
LRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDG
IFYTPQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWFKQDLPKYLFPEDPSYSSTMID
DEALKEVCEKFECSEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIMNEAKDFYLATSPPDS
FLDDHHLTRPHPERVPFLVAETPRARHTLDELNPQKSKHQGVRKAKWHLGIRSQSRPNDI
MAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTYSKMSLQLYQVDSRTYLLDFRSIDDE
ITEAKSGTATPQRSGSVSNYRSCQRSDSDAEAQGKSSEVSLTSSVTSLDSSPVDLTPRPG
SHTIEFFEMCANLIKILAQ
NT seq 1680 nt   +upstreamnt  +downstreamnt
atgcgcagactcagttcctggagaaagatggcgacagccgagaagcagaaacacgacggg
cgggtgaagatcggccactacattctaggggacacactgggggtcggcaccttcggcaaa
gtgaaggttggcaaacatgaattaactgggcataaagtggctgtgaagatactcaatcga
cagaagattcggagccttgatgtggtgggaaaaattcgcagagaaattcagaacctcaag
cttttcaggcatcctcatataattaaactgtaccaggtcatcagtacaccatctgatatt
ttcatggtgatggaatatgtctcaggaggagagctatttgattatatctgtaagaatgga
aggctggatgaaaaagaaagtcgacgtctgttccagcagatcctttctggtgtggattat
tgtcacaggcatatggtggtccatagagatttgaaacctgaaaatgtcctgcttgatgca
cacatgaatgcaaagatagccgattttggtctttcaaacatgatgtcagatggtgaattt
ttaagaacaagttgtggctcacccaactatgctgcaccagaagtaatttcaggaagattg
tatgcgggcccagaggtagatatatggagcagtggggttattctctatgctttattatgt
ggaacccttccatttgatgatgaccatgtgccaactctttttaagaagatatgtgatggg
atcttctatacccctcaatatttaaatccttctgtgattagccttttgaaacatatgctg
caggtggatcccatgaagagggccacaatcaaagatatcagggaacatgaatggtttaaa
caggaccttccaaaatatctctttcctgaggatccatcatatagttcaaccatgattgat
gatgaagccttaaaagaagtatgtgaaaagtttgagtgctcagaagaggaagttctcagc
tgtctttataacagaaatcaccaggaccctttggcagttgcttaccatctcataatagat
aacaggagaataatgaatgaagccaaagatttctatctggcgacaagcccacctgattct
tttcttgatgatcaccacctgactcgtccccatcctgaaagagtaccattcttggttgct
gaaacaccaagggcacgccacacccttgatgaattaaatccacagaaatccaaacaccaa
ggtgtaaggaaagcaaaatggcatttaggaattagaagtcaaagtcgaccaaatgatatt
atggcagaagtctgtagagcaattaaacaattggattatgaatggaaggttgtaaacccc
tattatttgcgtgtacgaaggaagaatcctgtgacgagcacttattccaaaatgagtcta
cagttataccaagtggatagtagaacttacctactggatttccgtagtattgatgatgaa
attacagaagccaaatcagggactgctactccacagagatcgggatcagttagcaactat
cgatcttgccagaggagtgattcagatgctgaggctcaaggaaaatcctcagaagtttct
cttacctcatctgtgacctcacttgactcttctcctgttgacctaactccgagacctgga
agtcatacaatagaattttttgagatgtgtgcaaatctaattaaaattcttgcacaataa

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