Aotus nancymaae (Ma's night monkey): 105726225
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Entry
105726225 CDS
T10127
Symbol
LRRK2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
anan Aotus nancymaae (Ma's night monkey)
Pathway
anan05012
Parkinson disease
anan05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
anan00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
105726225 (LRRK2)
05022 Pathways of neurodegeneration - multiple diseases
105726225 (LRRK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
anan01001
]
105726225 (LRRK2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
anan04131
]
105726225 (LRRK2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
anan04147
]
105726225 (LRRK2)
Enzymes [BR:
anan01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
105726225 (LRRK2)
Protein kinases [BR:
anan01001
]
Serine/threonine kinases: TKL group
LRRK family
105726225 (LRRK2)
Membrane trafficking [BR:
anan04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
105726225 (LRRK2)
Exosome [BR:
anan04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
105726225 (LRRK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ARM_LRRK2
Beta-prop_LRRK2
ANK_LRRK2
Pkinase
PK_Tyr_Ser-Thr
LRR_8
Roc
COR
LRR_4
Ras
LRR_14
LRR_9
WDR55
LRR_13
Beta-prop_RSE1_2nd
Beta-prop_EML_2
Arf
WD40_CDC20-Fz
Ank_2
Beta-prop_BBS7
LRR_NXF1-5
T2SSE
G-alpha
nSTAND3
AAA_22
ABC_tran
LRR_6
WD40_Prp19
AAA_16
PduV-EutP
Kdo
AAA_7
NACHT
TrwB_AAD_bind
MobB
cobW
Beta-prop_HPS5
AAA_29
GTP_EFTU
FtsK_SpoIIIE
AAA_23
MMR_HSR1
ResIII
WD40_WDHD1_1st
TsaE
WD40_like
TniB
ARM_LIN_2nd
SRP54
Motif
Other DBs
NCBI-GeneID:
105726225
NCBI-ProteinID:
XP_021529451
Ensembl:
ENSANAG00000036859
LinkDB
All DBs
Position
Unknown
AA seq
2527 aa
AA seq
DB search
MASGSSQGCEEDEETLKKLIVRLNNVQEGKQIETLVQILEDLLVFTYSEHASKLFQGKNI
HVPLLIVLDSYMRVASVQQVGWSLLCKLIEICPGTMQSLMGPQDVGNDWEVLGVHQLILK
MLTVHNASVNLSMIGLKTLDLLLTSGKITLLILDEESDIFLLIFDAMHSFPTNDEVQKLG
CKALHVLFERVSEEQLTEFVENKDYMILLSALKNFQEEEEIVLHVLHCLHSLAIPCNNVE
VLMSGNVRCYNIVVEAMKAFPFSEKIQEVSCCLLHRLTLGNFFNILVLNEVHEFVVKAVQ
QYPENTALQISALSCLALLTETIFLNQDLEEKNENQENDDEGEEDKLFWLEACYKALTWH
RKNKHVQEAACWALNNLLMYQSSLHEKIGDEDGHFPAHREVMLSMLMHSSSKEVFQASAN
ALSTLLEQNVNFRKILLSKGIYLNVLESMQKHIHSPEVAESGCKMLNHLFEGSNASLDTI
AAVVPKIITVMKNHETSLPVQLEALRAILHFIVPGMPEESREDTDSHHKLNMVKKQCFKN
DIHKLVLAALNRFIGNPGIQKCGLKVVSSIAHFPDALEMLSLEGAMDSVLHTLQMYPDDQ
EIQCLGLSLIGCLITKKNLCLGTGHLLAKILISSLQRFKDVAEVQTKGFQTILTILELSA
SFSKLLLNHSFDLVIFHQMSSNIMEQKDQQFLNLCCKCFAKVAMDDDLKNVLLERACDQN
NSIMVECLLLLGADANQAKEATSLICQVCEKESSPKLVELLLNSGSREQDVRKALTISIG
KGDSQIISLLLQRLALDVANNSICLGGFCIGKVEPSWLGPLFPDKTSNVRKQTNIASTLA
RMVIRYQMKSAMEEEAASGSNGNFSEDVLHKFDEWTFIPDSSMDSVFAQSDDLDSEGSEG
SFLVKKKSNSISVGEFYRDLALQRCSPNLQRHSNSLGPIFDHEDLLRQKRKILSSDDSLR
SSKLQSHMRHSESISSLASEREYITSLDLSANELRDIDALSQKCCISGHLEHLEKLELHQ
NALTSFPQQLCETLKSLTHLDLHSNKFTSFPSYLLKMNCIANLDVSRNDIGPSVVLDPAV
KCPTLKQFNLSYNQLSSVPENVADVVEKLEQLILEGNKISGICSPLRLKELKILNLSKNH
ISSLSENFLEACPKVESFSARMNFLAAMPFLPSSMTSLKLSQNKFTCIPEAILNLPHLRS
LDMSSNDIQYLPGPAHWKSLNLRELLFSHNQISILDLSEKAYLWSRVEKLHLSHNKLKEI
PPEIGSLENLTSLDVSYNLELRSFPNEMGKLSKIWDLPLDELRLNFDFKHIGCKAKDIIR
FLQQRLKKAVPYNRMKLMIVGNTGSGKTTLLQQLMKIKKSDLGMQSATVGIDVKDWPIQI
RGKRKRDLILNVWDFAGREEFYSTHPHFMTQRALYLAVYDLSKGQAEVDAMKPWLFNIKA
RASSSPVILVGTHSDVSDEKQRKACISKITKELLNKRGFPAIRDYHFVNATEESDALAKL
RKTIINESLNFKIRDQPVVGQLIPDCYVELEKIILSERKNVPIEFPVIDQKRLLQLVSEN
QLQLDENELPHAVHFLNESGVLLHFQDPALQLSDLYFVEPKWLCKIMAQILTVKVEGCPK
HPKGIISRRDVEKFLSKKRRFPKNYMSQYFKLLEKFQIALPIGEEYLLVPSSLSDHRPVI
ELPHCENSEIIIRLYEMPYFPMGFWSRLINRLLEISPYMLSGRERALRPNRMYWRQGIYL
NWSPEAYCLVGSEVLDNHPESFLKITVPSCRKGCILLGQVVDHIDSLMEEWFPGLLEIDI
CGEGETLLKKWALYSFNDGEEHKKILLDDLMKKAEEGDLLVNPDQPRLTIPISQIAPDLI
LADLPRNIMLNNDELEFEQAPEFLLGDGSFGSVYRAAYEGEEVAVKIFNKHTSLRLLRQE
LVVLCHLHHPSLISLLAAGIRPRMLVMELASKGSLDRLLQQDKASLTRTLQHRIALHVAD
GLRYLHSAMIIYRDLKPHNVLLFTLYPNAAIIAKIADYGIAQYCCRMGIKTSEGTPGFRA
PEVARGNVIYNQQADVYSFGLLLYDILTTGGRIVEGLKFPNEFDELAIQGKLPDPVKEYG
CVPWPMVEKLIKKCLKENPQERPTSAQVFDILNSAELTCLMRHILLPKNVIVECMVATHH
NSRNASIWLGCGHPNRGQLSFLDLNTEEYTSEEVADSRVLCLALVHLPVEKESWIVSGTQ
SGTLLVINTEDEKKRHTLEKMTDSITCLYCNSFPKQSKQKNFLLVGTADGNIAIFEDKTV
KLKGAAPLKILNIGNVSTPLMCLSESTNSTERNIMWGGCGTKIFSFSNDFTIQKFIETRT
NQLFSYAAFSDSNIIAVVVDTALYVAKKNSPVVEVWDKKTEKLCELIDCVHFLRELMVKV
NKESKHKMSYSGRVKTLCLQKNTALWIGTGGGHILLLDLSTRRVIRIIYNFCDSVRVMMT
AQLGSLKNVMLVLGYNWKSTEGTQHQKETQSCLTVWDINLPHEVQNLEKHIEMRKELAEK
MRGTSAE
NT seq
7584 nt
NT seq
+upstream
nt +downstream
nt
atggctagtggcagcagtcaggggtgcgaggaggacgaggaaactctgaagaagttaata
gtcaggctgaacaacgtccaggaaggaaaacagatagaaacgctggtccaaatcctggag
gatctgctggtgttcacgtactccgagcacgcctccaagttatttcaaggcaaaaatatc
cacgtgcctctgttgatcgtcttggactcgtatatgagagtcgcgagtgtgcagcaggtg
ggttggtcacttttatgcaaattaatagaaatctgtccaggtacaatgcaaagcttaatg
ggaccccaggatgttggaaatgattgggaagtccttggtgttcaccaattgattcttaaa
atgctaacagttcacaatgccagtgtaaatctgtcaatgattggactgaagaccttagat
ctcctcctaacttcaggtaaaatcaccttgctgatactggatgaagaaagtgatattttc
ttgttaatttttgatgccatgcactcatttccaaccaatgatgaagtccagaaacttgga
tgcaaagctttacatgtgctgtttgagagagtctcagaggagcaactgactgaattcgtt
gagaacaaagattatatgatattgttaagtgcattaaaaaattttcaagaagaagaggaa
attgtgcttcatgtgctgcattgtttacattctctagcgattccatgcaataatgtggaa
gtcctcatgagtggcaatgtcaggtgttataatattgtggtggaagctatgaaagcattc
cctttcagtgaaaaaattcaagaagtgagttgctgcttgctccataggcttacattaggt
aatttttttaatattctggtattaaacgaagtccacgagtttgtggtgaaagctgtgcag
cagtacccagagaacacggcgttacaaatctcagcactcagctgtttggcccttctcact
gagaccattttcttaaatcaagacttagaggaaaagaatgagaatcaggagaatgatgat
gagggggaagaagataaattgttttggctggaagcctgttacaaagcattaacgtggcat
agaaagaacaagcatgtgcaggaggctgcatgctgggcactaaataatctccttatgtac
caaagcagtttacatgagaagattggagatgaagatggccatttcccagctcatagggaa
gtgatgctctctatgctgatgcattcttcatcaaaagaagttttccaggcatctgcgaat
gcactgtcaactctcttagaacaaaatgttaatttcagaaagatcctgttgtcgaaagga
atatacttgaatgttttggagtcaatgcagaagcatatacattctcctgaagtggctgaa
agtggctgtaaaatgctaaatcatctttttgaaggaagcaatgcttccctggatacaata
gcagcagtggtccccaaaataataacagttatgaaaaatcatgagacatcattgccagtg
cagctggaggcgcttcgagctattttacattttatagtgccaggtatgccagaagaatcc
agggaggatacagactctcatcataagctaaatatggttaaaaaacaatgtttcaagaat
gatattcacaaactggtcctagcagctttgaacaggttcattggaaatcctgggattcag
aaatgtggattaaaagtagtttcttctattgcacattttcctgatgcgttagagatgtta
tccctggaaggtgctatggattcggtgcttcacacactgcagatgtatccagatgaccaa
gaaattcaatgtctgggtttaagtcttataggatgcttgattacaaagaagaacttatgc
ctaggaactggacatctgctagcaaaaattctgatttccagcttacaacgatttaaggat
gttgccgaagtacagactaaaggatttcagacaatcttaacaatcctcgaattgtcagca
tctttttccaagctgctgctgaatcattcatttgacttagtaatattccatcagatgtct
tccaatatcatggaacaaaaggatcaacagtttctaaacctctgttgcaagtgttttgca
aaagtagctatggatgatgacttaaaaaatgtgttgctagagagagcctgcgatcagaat
aacagcatcatggttgaatgcttgcttctattgggagcagatgccaatcaagcaaaggag
gcaacttctttaatttgtcaggtatgtgagaaagagagcagtcccaaattggtggaactc
ttattgaatagtggatctcgtgaacaagatgtacggaaagcgctgacgataagcattggg
aaaggcgacagccagatcatcagcttgctcttacagaggctggccctggatgtggccaac
aatagcatttgccttggaggattttgtataggaaaagttgaaccttcttggcttggtcct
ttatttccagataagacttctaatgtaaggaaacaaacaaatatagcgtctacactagca
agaatggtgatcaggtatcagatgaaaagtgctatggaagaagaagcagcctcaggcagc
aatggaaatttttctgaagatgtgctgcataaatttgatgaatggacctttattcctgac
tcttctatggacagtgtgtttgctcaaagtgatgatctggatagcgaaggaagtgaaggc
tcattccttgtgaaaaagaaatcaaattcaattagtgtaggagaattttaccgagatctt
gcattgcagcgttgttcaccaaatttgcaaaggcattccaattctttgggacccattttt
gatcatgaagatttactgaggcaaaaaagaaaaatattatcttcagatgattcactcagg
tcatcaaaacttcaatcccatatgaggcattcagaaagtatttcttctctggcttctgag
agagaatatattacatcactagacctttcagcaaatgaactaagagatattgatgcctta
agccagaaatgctgtataagtggtcatttggagcatcttgaaaagctggagcttcaccag
aatgcactcacgagctttccacaacagctatgtgaaactctgaagagtttgacacatttg
gacttgcacagtaataaatttacatcatttccttcttacttgttgaaaatgaattgcatt
gctaaccttgatgtctctcgaaacgacattggaccctcagtggttttagatcctgcagtg
aaatgtccaactctgaagcagtttaacctgtcatataaccagctgtcttctgttcctgag
aatgttgctgatgtggtagagaaactggagcagctcattttagaaggaaataaaatatca
ggaatatgctcccccttgagactgaaggaactgaagattttaaacctcagtaaaaatcac
atttcatccctatcagagaactttcttgaggcttgtcctaaagtggagagtttcagtgcc
agaatgaattttcttgctgctatgcctttcttgccttcttccatgacaagcctaaaatta
tctcaaaacaaatttacatgtattccagaagcaattttaaatcttccacacttgcggtct
ttagatatgagcagcaatgatattcaatatctaccaggtcctgcacactggaagtctttg
aacttaagggaactattatttagccataatcagatcagcatcctggacttgagtgaaaaa
gcatatttatggtctagagtagagaaactacatctttctcacaataaactgaaagagatt
cctcctgagattggctctcttgaaaatctgacatctctggatgtcagttacaacttggaa
ctaagatcctttcccaatgaaatggggaaattaagcaaaatatgggaccttcctttggat
gaactgcgtcttaactttgattttaaacacataggatgtaaagccaaagacatcataagg
tttcttcaacagcggttaaaaaaggctgtgccctataaccgaatgaaacttatgattgtg
ggaaatactgggagtggtaaaaccaccttattgcagcaattaatgaaaatcaagaaatca
gatcttggaatgcaaagtgccacagttggcatagatgtgaaagactggcctattcaaata
agaggcaaaagaaagagagacctcattctaaatgtgtgggattttgcaggtcgtgaggaa
ttctatagtactcatccccattttatgacccagcgagcattgtatcttgctgtctatgac
ctcagcaaaggacaggctgaagttgatgccatgaagccttggctctttaatataaaggct
cgtgcttcttcttctcctgtgattcttgttggcacacattcggatgtttctgatgagaag
cagcgcaaagcctgcataagtaaaatcaccaaggaactcttgaataagcgagggttccct
gccatccgagattaccactttgtgaatgccactgaggaatctgatgctttggcaaagctt
cggaaaaccatcataaatgagagccttaatttcaagatccgagatcagcctgttgttgga
cagctgatcccagattgctatgtagaacttgagaaaatcattttatcagagcgtaaaaat
gtgccaattgaatttcctgtaattgaccagaaacgattattacaacttgtgagtgaaaat
cagctgcagttagatgaaaatgagcttcctcatgcagttcactttctaaatgaatcagga
gtcctgcttcattttcaagacccagcactgcagttaagtgacttgtattttgtggaaccc
aagtggctttgtaaaatcatggcacagattttgacagtgaaagtggaaggttgtccaaaa
caccccaagggaattatttcacgtagagatgtggaaaaatttctttcaaagaaaaggaga
tttccaaagaactacatgtcacagtattttaagctcctggaaaaattccagattgctttg
ccaataggagaagaatatttgctggttccaagcagtttgtctgaccacaggcctgtgata
gagcttccccattgtgagaactctgaaattatcatccgactatatgaaatgccctatttt
ccaatgggattttggtcaagattaatcaatcgattacttgagatttcaccttacatgctt
tcagggagagaacgagcacttcgcccaaacagaatgtattggcgacaaggcatctacttg
aattggtctcctgaagcttattgtctggtaggatctgaagtcttagacaatcacccagag
agtttcttgaaaattacagttccttcctgtagaaaaggctgtattcttttgggccaagtt
gtggaccacattgattctctcatggaagaatggtttcctgggttgttggagattgatatt
tgtggtgaaggagaaactctattgaagaaatgggcgttatatagttttaacgatggtgaa
gaacataaaaaaatcttacttgatgacttgatgaagaaagcagaggaaggagatctctta
gtaaatccagatcaaccaaggctcaccattccaatatctcagatcgcccctgacttgatt
ttggctgacctgcctagaaatattatgttgaataatgatgagctggaatttgaacaagct
ccagagtttctcctaggtgatggcagttttggatcagtttatcgagcagcctatgaagga
gaagaggtggctgtgaagatttttaataagcatacatcacttaggctgttaagacaagag
ctggtggtgctttgccacctccaccacccgagtttgatatctttgctggcagcggggatt
cgtcccaggatgttggtgatggagttagcctccaagggttccttggatcgcctgcttcag
caagacaaagccagcctcaccagaaccctacagcacaggattgcactccatgtggctgat
ggtttgagatacctccactcggccatgatcatataccgagacttgaagccccacaatgtg
ctgcttttcaccctgtatcccaatgctgccatcattgcaaaaattgctgactacggcatt
gctcagtattgctgtagaatggggataaaaacgtcagagggcacaccagggtttcgtgca
cctgaagttgccagaggaaatgtcatttataaccagcaggctgatgtttattcatttggt
ttactactctatgacattttgacaactggaggaagaatagtagagggtttgaagtttcca
aatgagtttgatgaattagcaatacaaggaaaattacctgatccagttaaagaatatggt
tgtgtcccatggcctatggttgagaaattaattaaaaagtgtttgaaagaaaatcctcaa
gaaaggcctacttctgcacaggtctttgacattttgaattcagctgagttaacctgtctg
atgagacatattttattacctaaaaatgttattgttgaatgcatggttgctacacatcac
aacagcaggaatgcaagcatttggctgggctgtgggcaccccaacagaggacagctctca
tttctagatttaaatactgaagaatacacttctgaggaagttgctgatagcagagtattg
tgcttagccttggtgcatcttcctgttgaaaaggaaagctggattgtgtctgggacacag
tctggtactctcctggtcatcaatactgaagatgagaaaaagaggcataccctagaaaag
atgactgattccatcacttgtttgtattgcaattcctttcccaagcaaagcaaacaaaaa
aattttcttttggttggaactgctgatggcaatatagcgatttttgaagataagacagtt
aagcttaaaggagctgctcctttgaagatactaaatataggaaatgtcagcactccattg
atgtgtttgagtgaatccacaaattcaacggaaagaaacataatgtggggaggatgtggc
acaaagattttctccttttctaatgatttcaccattcagaaattcattgagacaaggaca
aatcaactattttcttatgcagctttcagcgattccaacatcatagcagtggtggtagac
actgccctctatgtcgctaagaaaaatagccctgttgtggaagtgtgggataagaaaact
gaaaaactctgcgaactcatagactgtgtgcactttttaagggagttaatggtaaaagta
aacaaggaatcaaaacacaaaatgtcttattctgggagggtgaaaactctctgccttcag
aagaacactgctctctggataggaactggaggaggccatattttactcctggatctttca
actcgtcgagttatacgtataatttacaacttttgtgattcagtcagagtcatgatgaca
gcacagctaggaagccttaaaaatgtcatgctggttttgggctacaactggaaaagtact
gaaggtacacaacaccagaaagagacacaatcttgcttgactgtttgggacatcaatctt
ccacatgaagtgcaaaatttagaaaaacacattgaaatgagaaaagaattagctgaaaaa
atgagaggaacatctgctgaataa
DBGET
integrated database retrieval system
