Aotus nancymaae (Ma's night monkey): 105726497
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Entry
105726497 CDS
T10127
Symbol
PLCG2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
KO
K05859
phosphatidylinositol phospholipase C, gamma-2 [EC:
3.1.4.11
]
Organism
anan Aotus nancymaae (Ma's night monkey)
Pathway
anan00562
Inositol phosphate metabolism
anan01100
Metabolic pathways
anan01521
EGFR tyrosine kinase inhibitor resistance
anan04012
ErbB signaling pathway
anan04014
Ras signaling pathway
anan04020
Calcium signaling pathway
anan04062
Chemokine signaling pathway
anan04064
NF-kappa B signaling pathway
anan04066
HIF-1 signaling pathway
anan04070
Phosphatidylinositol signaling system
anan04072
Phospholipase D signaling pathway
anan04360
Axon guidance
anan04370
VEGF signaling pathway
anan04380
Osteoclast differentiation
anan04517
IgSF CAM signaling
anan04611
Platelet activation
anan04613
Neutrophil extracellular trap formation
anan04625
C-type lectin receptor signaling pathway
anan04650
Natural killer cell mediated cytotoxicity
anan04662
B cell receptor signaling pathway
anan04664
Fc epsilon RI signaling pathway
anan04666
Fc gamma R-mediated phagocytosis
anan04670
Leukocyte transendothelial migration
anan04722
Neurotrophin signaling pathway
anan04750
Inflammatory mediator regulation of TRP channels
anan04919
Thyroid hormone signaling pathway
anan04933
AGE-RAGE signaling pathway in diabetic complications
anan04935
Growth hormone synthesis, secretion and action
anan05167
Kaposi sarcoma-associated herpesvirus infection
anan05169
Epstein-Barr virus infection
anan05170
Human immunodeficiency virus 1 infection
anan05171
Coronavirus disease - COVID-19
anan05200
Pathways in cancer
anan05205
Proteoglycans in cancer
anan05206
MicroRNAs in cancer
anan05214
Glioma
anan05223
Non-small cell lung cancer
anan05225
Hepatocellular carcinoma
Module
anan_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
anan00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
105726497 (PLCG2)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
105726497 (PLCG2)
04014 Ras signaling pathway
105726497 (PLCG2)
04370 VEGF signaling pathway
105726497 (PLCG2)
04064 NF-kappa B signaling pathway
105726497 (PLCG2)
04066 HIF-1 signaling pathway
105726497 (PLCG2)
04020 Calcium signaling pathway
105726497 (PLCG2)
04070 Phosphatidylinositol signaling system
105726497 (PLCG2)
04072 Phospholipase D signaling pathway
105726497 (PLCG2)
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
105726497 (PLCG2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
105726497 (PLCG2)
04613 Neutrophil extracellular trap formation
105726497 (PLCG2)
04625 C-type lectin receptor signaling pathway
105726497 (PLCG2)
04650 Natural killer cell mediated cytotoxicity
105726497 (PLCG2)
04662 B cell receptor signaling pathway
105726497 (PLCG2)
04664 Fc epsilon RI signaling pathway
105726497 (PLCG2)
04666 Fc gamma R-mediated phagocytosis
105726497 (PLCG2)
04670 Leukocyte transendothelial migration
105726497 (PLCG2)
04062 Chemokine signaling pathway
105726497 (PLCG2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
105726497 (PLCG2)
04919 Thyroid hormone signaling pathway
105726497 (PLCG2)
09156 Nervous system
04722 Neurotrophin signaling pathway
105726497 (PLCG2)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
105726497 (PLCG2)
09158 Development and regeneration
04360 Axon guidance
105726497 (PLCG2)
04380 Osteoclast differentiation
105726497 (PLCG2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
105726497 (PLCG2)
05206 MicroRNAs in cancer
105726497 (PLCG2)
05205 Proteoglycans in cancer
105726497 (PLCG2)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
105726497 (PLCG2)
05214 Glioma
105726497 (PLCG2)
05223 Non-small cell lung cancer
105726497 (PLCG2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
105726497 (PLCG2)
05171 Coronavirus disease - COVID-19
105726497 (PLCG2)
05167 Kaposi sarcoma-associated herpesvirus infection
105726497 (PLCG2)
05169 Epstein-Barr virus infection
105726497 (PLCG2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
105726497 (PLCG2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
105726497 (PLCG2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
anan04131
]
105726497 (PLCG2)
Enzymes [BR:
anan01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
105726497 (PLCG2)
Membrane trafficking [BR:
anan04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
105726497 (PLCG2)
Endocytosis
Macropinocytosis
Phospholipase C
105726497 (PLCG2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI-PLC-X
SH2
PI-PLC-Y
EF_HAND_2_PLCG
C2
SH3_1
SH3_9
PH
PH_12
EF_HAND_1_PLCG
SH2_1
SH3_2
PH_14
EF-hand_like
GDPD
Motif
Other DBs
NCBI-GeneID:
105726497
NCBI-ProteinID:
XP_021526721
Ensembl:
ENSANAG00000025033
UniProt:
A0A2K5D059
LinkDB
All DBs
Position
Unknown
AA seq
1265 aa
AA seq
DB search
MSTMASVDSLAEYEKSQIKRALELGTVMTVFSFRKSTPERRTVQVIMETRQVAWSKTADK
IEGFLDIMEIKEIRPGKNSKDFERAKAVRQKEDCCFTILYGNQFVLSTLSLAADSKEDAV
NWLSGLKILHQEAMNASTPTIIESWLRKQIYSVDQTRRNSISLRELKTILPLVNFKVSSA
KFLKDKFVEVGAHKDELSFEQFHLFYKKLMFEQQKSILDEFKKDSSVFILGNTDRPDASA
VYLHDFQRFLIHEQQEHWAQDLNKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENS
IWDEKYDAVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSTEAYIRCLRMGCRCIELDC
WDGPDGRPVIYHGWTRTTKIKFDDVVQAIKDHAFVTSSFPVILSIEEHCSVEQQRHMAKV
FKDVFGDLLLMKPTEASADQLPSPSQLREKIIIKHKKLGPRGDVDVNVEDKKDEHKQQGE
LYMWDSIDQKWTRHYCAIADAKLSFSDDIEQTVEEEVPQDIPPTELHFGEKWFHKKVEKR
TSAEKLLQEYCMETGGKDGTFLVRESETFPNDYTLSFWRSGRVQHCRIRSTMENGTLKYY
LTDNLTFSSIYALIQHYRETHLRCTEFELRLTDPVPNPNPHESKPWYYDSLSRGEAEDML
MRIPRDGAFLIRKREGSDSYAITFRARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYY
EKHSLYRKMRLRYPVTPELLERYNMERDINSLYDVSRMYVDPSEINPSMPQRTVKALYDY
KAKRSDELSFCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVEDISTADVEELEKQII
EDNPLGSLCRGILDLNTYNVVKAPQGKNQKPFVFILEPKKQGDPPVEFATDRVEELFEWF
QSIREITWKIDTKENNMKYWEKNQSIAIELSDLVVYCKPTSKTKDNLENPDFREIRSFVE
TKADSIIRQKPVDLLKYNQKGLTRIYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTADKY
MQMNHALFSLNGRTGYVLQPESMRTEKYDPMPPESQRKILMTLTVKVLGARHLPKPGRSI
ACPFVEVEVCGAEYDNSKFKTTVVNDNGLSPIWAPTQEKVTFEIYDPNLAFLRFVVYEED
MFSDPNFLAHATYPIKAIKSGFRSVPLKNGYSEDIELASLLVFCEMRPVLESEEELYSSC
RQLRRRQEELNNQLFLYDTHQNLRNANRDALVKEFNVNENQLQLYQEKCNKRLREKRVSN
SKFYS
NT seq
3798 nt
NT seq
+upstream
nt +downstream
nt
atgtccaccatggccagtgtggactcccttgcggaatatgagaagagccagatcaagaga
gccctggagctggggacggtgatgactgtgttcagcttccgcaagtctactcctgagcga
aggaccgtccaggtgatcatggagacaaggcaggtggcctggagcaagaccgccgacaag
atcgagggcttcttggatatcatggaaataaaagaaatccgcccagggaagaactccaaa
gatttcgagcgtgcaaaagcagttcgccagaaagaagactgctgcttcaccatcctatat
ggcaatcagttcgtcctcagcacactcagcttggcagctgactctaaagaggatgcagtt
aactggctctctggcttgaaaatcttacaccaagaagcgatgaatgcgtccacacccacc
attatcgagagttggctgagaaagcagatatattctgtggatcaaaccagaagaaacagc
atcagcctccgagagttgaagaccatcttgcccctggtcaacttcaaagtgagcagtgcc
aagttccttaaagataagtttgtggaagtaggagcacacaaagatgagctcagctttgaa
cagttccatctcttctataaaaaacttatgtttgaacagcaaaaatcgattctcgatgaa
ttcaaaaaggattcgtctgtgttcatcctggggaacacggacaggccggatgcctctgct
gtttaccttcatgactttcagaggtttctcatacatgaacagcaggagcactgggcacag
gatctgaacaaagtccgtgagcggatgacaaagttcatcgatgacactatgcgtgaaacc
gctgagcctttcttgtttgtggatgagttcctcacatacctgttttcacgagaaaacagc
atctgggatgagaaatatgacgcggtggacatgcaggacatgaacaaccccctgtctcat
tactggatctcctcgtcacataacacgtacctcacaggtgaccagctgcggagtgagtcg
tccacagaggcctacatccgctgtctgcgcatgggctgtcgctgcatcgaactggactgc
tgggacgggcccgatgggaggccggtcatctaccacggctggacgcggaccactaagatc
aagtttgatgacgtcgtgcaggccatcaaggaccatgcctttgtgacctcgagcttccca
gtgatcctgtccattgaggagcattgcagcgtagagcagcagcgccacatggccaaggtc
ttcaaagatgtatttggcgaccttcttctgatgaagcccacggaggccagcgctgaccag
ctgccctcacccagccagctgcgggagaagatcatcatcaagcataagaagctgggcccc
cgaggtgacgtggatgtcaacgtggaggacaagaaggatgagcacaagcaacagggagag
ctgtacatgtgggattccatcgaccagaaatggactcggcactactgcgccatcgccgac
gccaagctgtccttcagtgatgacattgaacagactgtggaggaggaagtgccccaggat
atacccccaacagagctgcattttggggagaaatggttccacaagaaggtggagaagagg
acgagtgctgagaagttgctgcaggaatactgcatggagacagggggcaaggatggcacc
ttcctggttcgggagagcgagaccttccccaatgactacactctgtccttctggcggtca
ggccgggtccagcactgccggatacgctccaccatggagaatgggaccctgaagtactac
ctgactgacaacctcaccttcagcagcatctacgccctcatccagcactaccgcgagacg
cacctgcgctgcaccgaattcgagctgcggctcacggacccagtgcccaaccccaacccc
cacgagtccaagccgtggtactatgacagcctgagtcgcggggaggcagaggacatgctg
atgaggatcccccgggatggagccttcctgatccggaagcgagagggcagcgactcctac
gccatcaccttcagggctaggggcaaggtgaagcactgtcgcatcaaccgggacggccgg
cactttgtgctgggaacctctgcctattttgagagcctggtggagctcgtcagttactat
gagaagcattcactctaccggaagatgagactgcgctaccccgtgacccccgagctcctg
gagcgctacaatatggaaagagatataaactccctttatgacgtcagcagaatgtatgtg
gatcccagtgaaatcaatccgtccatgcctcagagaactgtgaaagctctgtatgactac
aaagccaagcgaagcgatgagctgagcttctgccgtggcgccctcatccacaacgtctcc
aaggagcctgggggctggtggaaaggcgactatggaaccaggatccagcagtacttccca
tccaactatgtggaggacatctcaactgcagatgtcgaggagctggaaaagcagattatt
gaagacaatcccttagggtctctttgcagaggcatattggacctcaatacctataacgtc
gtgaaagccccacaggggaagaaccagaagccctttgtctttatcctggagcccaagaag
cagggtgatcctccagtggagtttgccacagacagggtggaggagctcttcgagtggttt
cagagcatccgagagatcacctggaagattgacaccaaggagaacaacatgaagtattgg
gagaagaaccagtccatcgccattgagctctctgacctggttgtctactgcaaaccaacc
agcaaaaccaaggacaacttagaaaatcctgactttagagaaatccgctcctttgtggag
acaaaggctgacagcatcatcagacagaagcccgtcgacctcctcaagtacaatcaaaag
ggtctgacccgcatctacccaaagggacaaagagttgactcttccaactatgaccccttc
cgcctctggctgtgcggttctcagatggtggcactcaatttccagacagcagataagtac
atgcagatgaatcacgcgttgttttctctcaatgggcgcacgggctacgttctgcagcct
gagagcatgaggacagagaaatacgacccgatgccacccgagtcccagaggaagatcctg
atgacactgactgtcaaggttctcggtgctcgccatctccccaaacctggacgaagtatt
gcctgtccctttgtagaggtggaagtctgcggagctgagtatgacaacagcaagttcaaa
acgacggttgtgaatgataatggcctcagccctatctgggctccaacacaggagaaggtg
acatttgaaatttatgacccaaacctggcatttctgcgcttcgttgtttacgaagaagat
atgttcagtgatcccaactttcttgctcatgccacttaccccattaaagcaatcaaatca
ggattcaggtctgttccgctgaagaatgggtacagtgaggacatcgagctggcttccctc
ctggttttctgtgaaatgcggccagtcctggagagcgaagaggaactttactcctcctgc
cgccagctgaggaggcggcaagaagaactgaacaaccagctctttctgtatgacacacac
cagaacctgcgcaatgccaaccgggatgccctggttaaagagttcaacgttaacgagaac
cagctccagttgtaccaggagaaatgcaacaagaggttaagagagaagagagtcagcaac
agcaagttttactcgtag
DBGET
integrated database retrieval system
