KEGG   Aotus nancymaae (Ma's night monkey): 105733476
Entry
105733476         CDS       T10127                                 
Symbol
CYP11A1
Name
(RefSeq) cholesterol side-chain cleavage enzyme, mitochondrial
  KO
K00498  cholesterol monooxygenase (side-chain-cleaving) [EC:1.14.15.6]
Organism
anan  Aotus nancymaae (Ma's night monkey)
Pathway
anan00140  Steroid hormone biosynthesis
anan01100  Metabolic pathways
anan04913  Ovarian steroidogenesis
anan04925  Aldosterone synthesis and secretion
anan04927  Cortisol synthesis and secretion
anan04934  Cushing syndrome
Module
anan_M00107  Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
Brite
KEGG Orthology (KO) [BR:anan00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    105733476 (CYP11A1)
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    105733476 (CYP11A1)
   04925 Aldosterone synthesis and secretion
    105733476 (CYP11A1)
   04927 Cortisol synthesis and secretion
    105733476 (CYP11A1)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    105733476 (CYP11A1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:anan00199]
    105733476 (CYP11A1)
Enzymes [BR:anan01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.6  cholesterol monooxygenase (side-chain-cleaving)
     105733476 (CYP11A1)
Cytochrome P450 [BR:anan00199]
 Cytochrome P450, animal type
  CYP11 family
   105733476 (CYP11A1)
SSDB
Motif
Pfam: p450 Cytomega_US3
Other DBs
NCBI-GeneID: 105733476
NCBI-ProteinID: XP_012331342
Ensembl: ENSANAG00000025836
VGNC: 83329
UniProt: A0A2K5D4T8
LinkDB
Position
Unknown
AA seq 521 aa
MLAKGLTPRSVLVKGCQTFLSAPREGLGRPRVPTGEGAGISTRSPRPFSEIPSPGDNGWL
NLYHFWRELGTHKIHLHQVQNFQKYGPIYREKLGNVESVYVIDPEDVALLFKFEGPSPER
FLIPPWVAYHQYYQRPVGVLLKKSAAWKRDRLALNQEVMVPETTKNFVPLLDAVSRDFVS
VLHRRIKKAGSGNFSGDISDDLFRFAFESITNVIFGERQGMLEEVVDPEAQRFIDAIYQM
FHTSAPMLNLPPDLFRLFRTKIWKDHVAAWDTIFNKAEAYTQNFTWELRQKGNVDHNYRG
ILYRLLGDSRLPFEDIKANVTEMLAGGVDTTSMTLQWHLYEMARNLKVQDMLRAEVLAAR
RQAQGDTATMLQLVPLLKASIKETLRLHPISVTLQRYLVNDLVLRDYMIPAKTLVQVSLY
ALGREPTFFFHPENFDPARWLSKDKSIIHFRNLGFGWGVRQCLGRRIAELEMTIFLINML
ENFRVEIQHLGDVGTTFNLILMPEKPISFTFRPINQEATQE
NT seq 1566 nt   +upstreamnt  +downstreamnt
atgctggccaaaggtcttaccccacgctcagtcctggtcaaaggctgccaaacctttctg
agtgcccccagggaggggctggggcgacccagggtgcccaccggcgagggagccggaatc
tccactcgcagtcctcgcccattcagtgagatcccctcccctggtgacaatggatggcta
aatctgtaccatttctggagagagttgggcacacacaaaatccaccttcaccaagtccag
aatttccagaagtatggccccatttacagggagaagcttggcaatgtggagtcggtttat
gtcatcgaccctgaagatgtggcccttctctttaagttcgagggccccagcccggaacga
ttcctcatcccgccctgggtcgcctatcaccagtattaccagagaccagtaggagtcctg
ttgaagaagtcagcagcctggaagagagaccgactggccctgaaccaggaggtgatggtt
ccagagaccaccaagaactttgtgcccttgttggatgcagtgtctcgggactttgtcagt
gtcctgcacaggcgcatcaagaaggcgggctctggaaatttctcaggggacatcagtgat
gacctgttccgctttgcctttgagtccatcactaatgtcatttttggggagcgccagggg
atgctggaggaggtagtggaccctgaggcccagcggttcatcgacgccatctaccagatg
ttccacaccagcgcccccatgctcaacctccccccagacctgttccgtctgttcaggacc
aagatctggaaggaccatgtggccgcgtgggacacgattttcaataaagctgaggcatac
acccagaacttcacctgggaattgagacagaaaggaaatgttgaccacaattaccgtggc
atcctctacagactcctgggagacagcaggctgcccttcgaggacatcaaggccaacgtc
acggagatgctggcaggaggtgtggacacgacatccatgaccctgcagtggcacttgtac
gagatggcacgcaacctgaaggtgcaggatatgctgcgggcagaggttttggccgcccgg
cgccaggcccagggagacacggccacaatgctgcagctggtgccactcctgaaagccagc
atcaaggagactctgagactccaccccatctccgtgaccctgcagagatatcttgtaaat
gatctggttcttcgagattacatgattcctgccaagacactggtgcaggtgtccctctat
gctctgggccgagagcccaccttcttcttccacccggaaaattttgacccagcccgatgg
ctgagcaaagacaagagcatcattcacttccggaacttgggctttggctggggtgtgcgg
cagtgtctgggacggcggattgccgagctggagatgaccatcttcctcatcaatatgctg
gagaacttcagagttgaaatccaacatctcggtgatgtaggcaccacattcaacctcatc
ctgatgcctgaaaagcccatctccttcaccttccggcccattaaccaggaagcaacccag
gagtga

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