Actinomyces naeslundii: ATCC27039_12370
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Entry
ATCC27039_12370 CDS
T05566
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
ane
Actinomyces naeslundii
Pathway
ane00300
Lysine biosynthesis
ane00550
Peptidoglycan biosynthesis
ane01100
Metabolic pathways
ane01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
ane00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
ATCC27039_12370 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
ATCC27039_12370 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
ATCC27039_12370 (murF)
Enzymes [BR:
ane01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
ATCC27039_12370 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
BDH77111
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Position
complement(1437789..1439243)
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AA seq
484 aa
AA seq
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MNLSLSQIAAAVGGRLIGPDATVTGPVVTDSRQASPGALFVAVHGERTDGHAHLGSAGAL
GAVGAIVSDLKAARTGLSEEAAEAAEAEDLPMGLVLVEDTVVALGALARTHLAGLRQGAV
DRGERLTVVAMTGSVGKTTTKDLTRQLLAASGPTVAPRASFNNEIGLPLTVLEADESTRY
LVLEMGASGAGHIAYLTDIAPLDAAAVLMIGHAHMGGFGSIEGVAAAKAEIIAGLLPEGT
AILNADDARCAAMAKLAPARVLTFSAQGEPADLQAENVVLDEAACAAFDLHLPGLDAPRR
VQLAVAGAHNVANALAAAGLALAAGLEPELIAERLGSVSIESPHRMDVSELSGDLLLIDD
SYNANIDSMTAALAALPALAGSRRRVVVVSEMLELGESSAADHARTGELAAQAGAAMLIG
IGSTQEALDAARARGVEVVGFEDSATAISQIDALLSDGDAVLVKGSNGSGAWRLADHLKE
VRPR
NT seq
1455 nt
NT seq
+upstream
nt +downstream
nt
atgaacctcagcctgagtcagatcgcagccgccgtcggcggcagactcatcggcccggac
gcgaccgtgaccggccccgtcgtcaccgactcccgtcaagcctccccaggagcgctgttc
gtcgccgtccacggcgaacgcactgacggccatgcccacctgggctccgccggcgccctg
ggcgccgtcggagccatcgtctccgacctgaaggccgcccggaccgggctgtccgaggag
gctgcggaggctgcggaggctgaggacctgcccatgggactcgtcctcgtggaggacacc
gtcgtcgccctgggagcgttggcccgcacccacctggccggtctgcgccagggcgccgtg
gatcgcggtgagaggctcaccgtggtggcgatgaccggctcggtgggcaagaccaccacc
aaggacctcactcgtcagctcctggccgcctccggccccacagtggcccccagggccagc
ttcaacaacgagatcggcctgccgctgaccgtgctggaggccgacgagtccacccgctac
ctcgtcctggagatgggcgcctccggagccgggcacatcgcctacctcaccgacatcgcg
cccctggacgcggccgcggtcctcatgatcggccatgcccacatgggcgggttcggctcc
atcgagggggtggccgccgccaaggcggagatcatcgcgggcctgctgcctgaggggacc
gccatcctcaacgccgacgacgcccgttgcgccgcgatggccaagctcgcaccggcgcgg
gtcctcaccttctccgcccagggtgagcccgccgacctgcaggccgagaacgtcgtcctc
gatgaggccgcctgcgcggccttcgacctccacctgcccgggctcgacgccccccggcgc
gtccagctggccgtggccggcgcccacaacgtggccaacgccctggctgccgcggggctg
gctctggccgcggggctggagcccgagctcatcgccgaacggctcggctccgtcagcatt
gagagcccccaccgcatggacgtgtcggagctcagtggcgatcttctccttatcgacgac
tcctacaacgccaacatcgactccatgacggccgcgctggccgcgctgccggctctggcc
ggcagtcggcgccgcgtcgtcgtggtttccgagatgctcgagctgggggagtcctccgcc
gccgaccacgctcgtaccggggagctagcggcccaggccggagccgctatgctcatcggc
atcggctccacccaggaggcgctcgacgcagcccgggcccgaggggtcgaggtcgtcggc
tttgaggactccgcgaccgccatctcccagatcgacgcgctcctgtccgacggcgacgcc
gtcctggtcaagggctccaacggatcaggcgcctggcgcttggccgaccacctcaaggag
gtacgtccccgatga
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