Aquipluma nitroreducens: AQPE_3379
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Entry
AQPE_3379 CDS
T09507
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
anf
Aquipluma nitroreducens
Pathway
anf00300
Lysine biosynthesis
anf00550
Peptidoglycan biosynthesis
anf01100
Metabolic pathways
anf01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
anf00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
AQPE_3379
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
AQPE_3379
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
AQPE_3379
Enzymes [BR:
anf01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
AQPE_3379
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
BRCT
Motif
Other DBs
NCBI-ProteinID:
BBE19203
UniProt:
A0A5K7SC93
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Position
complement(3772750..3774042)
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AA seq
430 aa
AA seq
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MEIANLYAIFRNHPTVTTDSRNIPANSIFFALKGDNFNGNAFANEAILKGAAYAVIDEPE
SATNDKMILVEDVLLSLQQLAQYHRNQLGLPILAITGTNGKTTTKELIAAVLSKKFRVNS
TKGNLNNHIGVPLTLLSMSTETEFGVVEMGANHPGEIKILCEIANPDFGLITNIGKAHLE
GFGSFEGVIKTKSEMYDFIRNNGGKCFVNADNSLLTKQANHIEQISYGKSTDYFMAGELA
STDNYLVVKALFQKGWLYLKSKLIGDYNFENLLAAACVGKYFEVDPLLIQEAIAEYSPSN
NRSQLIQKAKNTIIMDAYNANPTSMMAALTNFAGIRHENKCIILGDMLELGTVSAEEHQK
ITDFIEEQKFSEVYLIGPQFKNTIDRTQKKKFYQVELLSNYLKTQPIENKLILIKGSRGI
HLEKILELLP
NT seq
1293 nt
NT seq
+upstream
nt +downstream
nt
atggaaatcgccaacttatatgcaatctttaggaatcacccgacagtaactactgattca
agaaacataccggccaatagcatctttttcgctttgaaaggtgacaatttcaatggtaat
gcctttgcgaacgaagccatattgaaaggagcagcatatgcagtaattgatgaaccggaa
tctgcaacgaatgataaaatgatacttgttgaggatgtattgcttagtcttcaacagctt
gctcaatatcatcggaaccaattgggattaccaattctggcgattacaggaacaaatggc
aaaacaactacaaaagagctgatcgcagcggttctctcgaaaaaattcagggttaattcc
actaaaggtaacctgaataatcacattggtgttcctttgactttactttcaatgagtaca
gaaactgaattcggagtggttgaaatgggcgccaatcatccaggagaaatcaaaattctc
tgcgagattgccaatcctgattttggcctaatcactaatattgggaaagcgcatctggaa
ggttttggctcatttgaaggtgtcataaaaaccaagtcagaaatgtatgatttcatcaga
aataatggaggcaagtgctttgtgaatgccgacaattctctattgactaaacaggctaat
catattgaacaaataagctacggaaaatcaactgattatttcatggccggagagcttgca
agtaccgacaactatctagtcgttaaagcgcttttccaaaaaggttggctttatctcaaa
tcgaaactgattggtgattataatttcgaaaacctattggcagcagcctgcgtcggtaaa
tattttgaagttgacccgttgcttatacaagaagcaatagcagaatattccccgtcaaat
aaccgctctcagctgatccaaaaagcgaaaaacaccatcatcatggatgcatacaatgcg
aatccaacgagcatgatggctgccctgactaatttcgcaggcatccgacatgaaaataaa
tgcatcattttgggcgatatgcttgaactgggcactgtttcggcagaagagcaccaaaaa
attacagattttattgaggaacaaaaattttcggaagtatatcttatcggccctcaattt
aaaaatacaattgaccggacacaaaaaaagaagttctatcaagtcgaacttctttcaaac
tacctaaaaacacaacctattgaaaataaactaattcttattaaaggttcaagaggaata
caccttgagaaaattcttgaattgctaccttaa
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