Arvicanthis niloticus (African grass rat): 117702774
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Entry
117702774 CDS
T08817
Symbol
Fpgs
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
anu
Arvicanthis niloticus (African grass rat)
Pathway
anu00790
Folate biosynthesis
anu01100
Metabolic pathways
anu01240
Biosynthesis of cofactors
anu01523
Antifolate resistance
anu04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
anu00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
117702774 (Fpgs)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
117702774 (Fpgs)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
117702774 (Fpgs)
Enzymes [BR:
anu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
117702774 (Fpgs)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
117702774
NCBI-ProteinID:
XP_034349834
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Position
2:complement(9845140..9855940)
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AA seq
587 aa
AA seq
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MSWARSHLCSALSLAAVSARGATTEGAARRWLSAWPAPQEPGMEYQDAVRTLNTLQTNAS
YLEQVKRQRSDPQAQLEAMEMYLARSGLQVEDLNRLNIIHVTGTKGKGSTCAFTERILRN
YGLKTGFFSSPHLVQVRERIRINGKPISPELFTKHFWSLYHQLEEFKDDDHTSMPSYFRF
LTLMAFHVFLQEKVDLAVVEVGIGGAFDCTNIIRRPVVCGVSSLGIDHTSLLGDTVEKIA
WQKGGIFKPGVPAFTVLQPEGPLAVLRDRAQQISCPLYLCPPLEALEAVGLPLSLGLEGE
HQRPNAALALQLAHCWLEQQGHHDIQELKVSRPSIRWQLPLAPVFRPTAHMRRGLRDTEW
PGRTQILRRGPLTWYLDGAHTTSSVQACVHWYCQSLERSKRTDGGPEVHVLLFNSTGDRD
SAALLKLLQPCQFDYAIFCPNVTEVSSVGNADQQNFTVTLDQVLLRCLQHQQHWNCLVEK
QASSNLWSSYGPEPAGPGSLLLAPHPPQPTSKSSLVFSCISHALQWISQGRDPIFQPQSP
PRSLLNHPTANSGASILREAAAIHVLVTGSLHLVGGVLKLLDPSMSQ
NT seq
1764 nt
NT seq
+upstream
nt +downstream
nt
atgtcgtgggcgcggagccacctgtgctcggctctgtctctggcagctgtttctgcgcgc
ggtgcaacgacggagggcgcggcgaggcggtggttgagcgcgtggccagcgccgcaggag
ccgggcatggagtatcaggatgctgtgcgcacgctcaacaccctgcaaaccaatgccagc
tacctggagcaggtaaagcgtcaacggagtgaccctcaggcgcagctggaggctatggag
atgtacctggcacggagtggactgcaggtagaggacttgaacaggctaaacattatccat
gtcactgggaccaaaggaaagggctccacctgtgccttcaccgaacggatcctgcggaat
tacggtctgaagactggcttctttagctctccccacctggtgcaggtgcgtgagcggatt
cgaatcaacgggaagcccatcagccctgagctctttaccaagcacttctggagcctctac
caccagctggaggaattcaaggatgacgaccacacttccatgccctcttacttccgcttc
ctcacactcatggccttccacgtcttcctccaagagaaggtggatctggcagtggtggag
gtgggcatcggcggggcttttgactgcaccaacatcatcagaaggccagtggtgtgtgga
gtctcttctctcggcattgaccacaccagtcttttaggagatacggtggagaaaatagca
tggcagaaagggggcatctttaagcctggtgtccctgccttcactgtgctacagccagaa
ggtcccctggctgtgctgagggatcgagcccagcagatctcatgccccctgtacctgtgt
ccacccttggaagccctggaggcggttggactgccattgagcctgggcctagagggagag
caccagcggcctaatgcagccttagccttgcagctggcccattgttggctggagcagcag
ggccaccatgacattcaggagctgaaggtatccaggccaagcatacggtggcagctgccc
ctggcacctgtgttccgtcctactgcccacatgagacgtgggcttcgggacacagaatgg
cctggtcggacacagatactccggcggggacctcttacatggtacctggatggcgctcat
accaccagcagtgtgcaggcctgtgtgcactggtactgccagtcattggagcgcagcaaa
cgcaccgatggtgggcctgaagtacacgtcttgctcttcaactccacgggtgacagggac
tccgctgccctgctgaagttgctgcagccctgccagtttgactatgctatcttctgcccc
aatgtgacagaggtttcatccgtaggaaatgcagaccagcagaacttcactgtgactctg
gaccaggtgctgctccgctgtctccaacaccagcaacattggaactgcctggtggagaaa
caggccagctccaacctctggagcagctatggcccagaacctgcggggccaggctccctg
ctgctggcaccacacccacctcaacctactagcaagagctcccttgtttttagctgtatc
tcccatgccttgcagtggatcagccaaggccgtgatcccatctttcagcctcagagccct
ccaaggagccttctcaaccaccccacagccaacagtggggccagcattctccgggaggct
gctgccatccatgtactggttacaggaagcctgcacctggtgggtggggttctaaagcta
ctggatccctctatgtcccagtag
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