| Entry |
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| Symbol |
Abcc4
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| Name |
(RefSeq) multidrug resistance-associated protein 4
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| KO |
| K05673 | ATP-binding cassette, subfamily C (CFTR/MRP), member 4 |
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| Organism |
anu Arvicanthis niloticus (African grass rat)
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| Pathway |
| anu04981 | Folate transport and metabolism |
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| Brite |
KEGG Orthology (KO) [BR:anu00001]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
117705860 (Abcc4)
09132 Signal transduction
04024 cAMP signaling pathway
117705860 (Abcc4)
09150 Organismal Systems
09154 Digestive system
04976 Bile secretion
117705860 (Abcc4)
04981 Folate transport and metabolism
117705860 (Abcc4)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
117705860 (Abcc4)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:anu02000]
117705860 (Abcc4)
Transporters [BR:anu02000]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
117705860 (Abcc4)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
3:5603788..5822565
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| AA seq |
1325 aa
MLPVHTGVKPNPLQDANLCSRVFFWWLNPLFKTGHKRRLEEDDMFSVLPEDRSKHLGEEL
QGYWDKEVLRAKKNARKPSLTKAIIKCYWKSYVILGIFTLIEESTRVVQPIFLGKIIDYF
EKYDPANSVALHTAYGYAAVLSVCTLILAILHHLYFYHVQCAGMRLRVAMCHMIYRKALR
LSNSAMGKTTTGQIVNLLSNDVNKFDQVTIFLHFLWAGPLQAIAVTILLWVEIGISCLAG
MAVLVILLPLQSCIGKLFSSLRSKTAAFTDARIRTMNEVITGMRIIKMYAWEKSFADLIT
NLRKKEISKILGSSYLRGMNMASFFIANKVILFVTFTTYVLLGNKITASHVFVAMTLYGA
VRLTVTLFFPSAIERVSEAFVSIQRIKNFLLLDELPQRKAQEPSDGKAIVHVQDFTAFWD
KTLDTPTLQGLSFTARPGELLAVVGPVGAGKSSLLSAVLGELPPTSGLVSVHGRVAYVSQ
QPWVFSGTVRSNILFGKKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGATLSGGQK
ARVNLARAVYQDADIYLLDDPLSAVDAEVGKHLFQLCICQTLHQKITILVTHQLQYLKAA
SHILILKDGEMVQKGTYTEFLKSGVDFGSLLKKENEEAEPSPAPGTPTLRNRTFSEASIW
SQQSSRPSLKDGAPEGQDAENTQATQPEESRSEGRIGFKAYKNYFTAGASWFFIIFLVLL
NMAGQVFYVLQDWWLSYWANKQGALNNTKNANGNVTETLDLSWYLGIYAGLTAVTVLFGI
ARSLLVFYILVNASQTLHNRMFESILRAPVLFFDRNPIGRILNRFSKDIGHMDDLLPLTF
LDFIQTLLLVISVIAVAAAVIPWILIPLVPLSVIFLVLRRYFLETSRDVKRLESTTRSPV
FSHLSSSLQGLWTIRAYKAEERCQELFDAHQDLHSEAWFLFLTTSRWFAVRLDAICAIFV
IVVAFGSLILAKTLDAGQVGLALSYALTLMGMFQWSVRQSAELENMMISVERVIEYTDLE
KEAPWECKKRPPPGWPHEGVIIFDNVNFTYSLDGPLVLKHLTALIKSREKVGIVGRTGAG
KSSLISALFRLSEPEGKIWIDKILTTEIGLHDLRKKMSIIPQEPVLFTGTMRKNLDPFNE
HTDEELWNALEEVQLKEAIEDLPGKMDTELAESGSNFSVGQRQLVCLARAILKKNRILII
DEATANVDPRTDELIQQKIREKFAQCTVLTIAHRLNTIIDSDKIMVLDSGRLREYDEPYV
LLQNPESLFYKMVQQLGKGEAAALTETAKQVYFRRNYPDITFTNPVVMNTSNGQPSALTI
FETAL |
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| NT seq |
3978 nt +upstreamnt +downstreamnt
atgctgccggtgcacaccggggtgaaacccaacccgctgcaggacgccaacctctgctcg
cgcgtgttcttctggtggctcaacccgttgtttaaaactggtcataagcgaagactggaa
gaagatgatatgttttcagtgcttcccgaagatcgctcaaagcaccttggagaggaactg
caagggtactgggataaagaagttctgcgagccaagaagaatgcaaggaagccttccttg
acgaaggcaatcataaaatgttactggaaatcttacgtgattttgggaatttttacgtta
attgaggagagcacccgagtagtccagcccatatttttagggaaaattattgattatttt
gagaagtatgaccccgccaactcggtggctttgcacacggcttatggctacgcagcggtg
ctgtcagtgtgcacgctcatcctggccatactacatcacttgtacttttaccacgtgcag
tgcgccgggatgaggctgcgggtcgccatgtgccacatgatttaccggaaggcactccgg
ttaagcaactcggccatggggaagactaccacgggccagatagtcaacctgctgtccaac
gacgtgaacaagtttgaccaagtgacaatcttcttgcactttctgtgggcggggccgctg
caggccattgcggtaaccatccttctctgggtggaaataggaatctcctgtctggcgggc
atggccgttctggttattcttctgcctctgcaaagctgcatcgggaaactgttctcgtca
cttcggagtaaaacagctgctttcacggatgccaggatccggaccatgaatgaagtcata
acaggcatgaggataataaagatgtatgcatgggagaagtcgtttgctgacctcattacc
aacctgagaaagaaggaaatttccaagattctgggcagctcctacctcagagggatgaac
atggcatcgtttttcatcgcaaacaaagtcatcctgttcgtgaccttcaccacctacgtg
ctgcttggcaataagattacggctagccacgtgtttgtggcaatgactctgtacggtgct
gttcggttgacagtcaccctcttcttcccgtcagccattgagagagtgtcagaggcgttt
gtcagcattcagaggatcaagaactttctgttgcttgatgaactgccacagcgcaaagcc
caggaaccatctgatggcaaagccatcgtgcacgtgcaagattttaccgctttctgggac
aagacattagacactccaaccctgcaaggtctttcctttactgccagacccggtgagttg
ttagccgtggttggcccagtcggtgccggcaagtcgtcactgttgagtgcggtgctgggt
gagctgcctcccaccagcggcctggtcagcgtgcatgggagagtcgcctacgtttcccag
cagccctgggtgttctccggaaccgtgaggagcaatattttatttgggaagaaatatgag
aaggaacgatatgagaaagtgatcaaggcctgtgcgctgaagaaggacttgcagcttctg
gaggacggggatctgactgtcataggagaccggggagccacactgagcggaggccagaaa
gcacgggtgaacttggcacgggcggtctaccaggacgctgacatctacctccttgacgat
ccactcagtgctgttgatgcagaagtgggcaagcatctgttccaactgtgcatctgtcag
actttgcaccagaagatcaccattttagtgactcaccagttacagtacctcaaagctgca
agccacatcctcatactgaaagatggtgagatggtgcagaaggggacttacaccgagttt
ctgaagtctggtgtagattttggttccctgttaaagaaagaaaatgaggaagcagagccc
tccccggccccaggaaccccgacactcagaaaccgaaccttctccgaggcctcgatttgg
tctcagcagtcatccagaccctcgttgaaagacggggccccagagggtcaagacgcagag
aacacacaggccacacaaccagaggagagccgctcagaagggagaatcggcttcaaggcc
tacaagaattacttcaccgcgggcgcctcctggtttttcatcattttccttgttctgctt
aacatggcgggtcaggttttctatgttcttcaggactggtggctttcctactgggcgaac
aagcaaggtgcactgaacaataccaaaaatgcgaacggaaatgtaacggagaccctagat
ctcagctggtatttaggaatttacgcaggtttaactgcggtcaccgtcctttttggcata
gccagatccctactggtgttctacatccttgtgaatgcttcccaaactttgcacaacagg
atgtttgagtcgatcctgagggctcccgtgttgttcttcgatagaaatccaataggaaga
attttaaatcgtttctccaaggacatcggacacatggacgacttgcttcccctgacgttt
ctagacttcatccagacattgctccttgtcataagtgtgatcgccgtggcggcagccgtg
atcccttggatcctcatccccttggttccactctcagtcatcttcctggttctccggaga
tacttcttagaaacgtcacgggatgtcaagcgcctggagtccacaacacggagcccggtg
ttctcccatttatcatcctccctccagggactctggaccatccgggcttataaagctgaa
gagaggtgccaggagctgtttgatgcacaccaggacttgcattcagaggcttggttcttg
ttcctgacgacctcgagatggttcgctgtgcgtctggacgccatctgcgccatctttgtc
atcgtcgttgcctttgggtccctgattctggcaaagactttggatgctgggcaggttggc
ctggccttgtcctacgccctcacgctcatggggatgttccagtggtctgtgcgacagagc
gccgaactagagaatatgatgatctctgtggagagggtgattgaatacacggacctagag
aaggaggcaccctgggaatgcaagaagcgcccacccccaggctggccccacgaaggagta
atcatctttgacaatgtgaacttcacctacagcttagacgggcctctggttctgaagcac
ctgactgcactcatcaagtccagagaaaaggttggaattgtgggaagaactggagctgga
aaaagttccctcatctcagcactcttcaggctgtcagaaccagaagggaaaatctggatc
gataagatcttgacaactgaaattggacttcatgacttaaggaagaagatgtcaatcata
cctcaggaacctgttctgttcactggaaccatgaggaagaacctggaccccttcaatgag
cacacggacgaggagctgtggaacgccttagaggaggtacaacttaaagaggccattgaa
gaccttcctggtaaaatggatactgaattagcagagtctggatccaatttcagtgttgga
cagagacagttagtgtgccttgcgagggcaattctaaagaaaaaccggatattgatcatc
gatgaagcaactgcaaatgtggatccaagaactgatgagttaatacaacagaaaatccgg
gagaagtttgcccagtgcacggtgctcaccatcgctcacagactgaacaccatcattgac
agtgacaagataatggttttggattcaggaagactgagagaatatgatgagccgtatgtt
ttgctgcagaatccagagagcctcttttacaagatggttcagcagctgggcaagggcgaa
gccgctgccctcacagagacagcaaaacaggtgtacttcagacggaattatccagatatt
acattcaccaatccagtggttatgaacacctccaatggacagccgtcagccttaacgata
tttgaaacagcattgtga |
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