KEGG   Arvicanthis niloticus (African grass rat): 117706625
Entry
117706625         CDS       T08817                                 
Symbol
Ppp3ca
Name
(RefSeq) serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X1
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
anu  Arvicanthis niloticus (African grass rat)
Pathway
anu04010  MAPK signaling pathway
anu04020  Calcium signaling pathway
anu04022  cGMP-PKG signaling pathway
anu04114  Oocyte meiosis
anu04218  Cellular senescence
anu04310  Wnt signaling pathway
anu04360  Axon guidance
anu04370  VEGF signaling pathway
anu04380  Osteoclast differentiation
anu04625  C-type lectin receptor signaling pathway
anu04650  Natural killer cell mediated cytotoxicity
anu04658  Th1 and Th2 cell differentiation
anu04659  Th17 cell differentiation
anu04660  T cell receptor signaling pathway
anu04662  B cell receptor signaling pathway
anu04720  Long-term potentiation
anu04724  Glutamatergic synapse
anu04728  Dopaminergic synapse
anu04921  Oxytocin signaling pathway
anu04922  Glucagon signaling pathway
anu04924  Renin secretion
anu05010  Alzheimer disease
anu05014  Amyotrophic lateral sclerosis
anu05020  Prion disease
anu05022  Pathways of neurodegeneration - multiple diseases
anu05031  Amphetamine addiction
anu05152  Tuberculosis
anu05163  Human cytomegalovirus infection
anu05166  Human T-cell leukemia virus 1 infection
anu05167  Kaposi sarcoma-associated herpesvirus infection
anu05170  Human immunodeficiency virus 1 infection
anu05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
anu05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:anu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    117706625 (Ppp3ca)
   04310 Wnt signaling pathway
    117706625 (Ppp3ca)
   04370 VEGF signaling pathway
    117706625 (Ppp3ca)
   04020 Calcium signaling pathway
    117706625 (Ppp3ca)
   04022 cGMP-PKG signaling pathway
    117706625 (Ppp3ca)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    117706625 (Ppp3ca)
   04218 Cellular senescence
    117706625 (Ppp3ca)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    117706625 (Ppp3ca)
   04650 Natural killer cell mediated cytotoxicity
    117706625 (Ppp3ca)
   04660 T cell receptor signaling pathway
    117706625 (Ppp3ca)
   04658 Th1 and Th2 cell differentiation
    117706625 (Ppp3ca)
   04659 Th17 cell differentiation
    117706625 (Ppp3ca)
   04662 B cell receptor signaling pathway
    117706625 (Ppp3ca)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    117706625 (Ppp3ca)
   04921 Oxytocin signaling pathway
    117706625 (Ppp3ca)
   04924 Renin secretion
    117706625 (Ppp3ca)
  09156 Nervous system
   04724 Glutamatergic synapse
    117706625 (Ppp3ca)
   04728 Dopaminergic synapse
    117706625 (Ppp3ca)
   04720 Long-term potentiation
    117706625 (Ppp3ca)
  09158 Development and regeneration
   04360 Axon guidance
    117706625 (Ppp3ca)
   04380 Osteoclast differentiation
    117706625 (Ppp3ca)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    117706625 (Ppp3ca)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    117706625 (Ppp3ca)
   05170 Human immunodeficiency virus 1 infection
    117706625 (Ppp3ca)
   05163 Human cytomegalovirus infection
    117706625 (Ppp3ca)
   05167 Kaposi sarcoma-associated herpesvirus infection
    117706625 (Ppp3ca)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    117706625 (Ppp3ca)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    117706625 (Ppp3ca)
   05014 Amyotrophic lateral sclerosis
    117706625 (Ppp3ca)
   05020 Prion disease
    117706625 (Ppp3ca)
   05022 Pathways of neurodegeneration - multiple diseases
    117706625 (Ppp3ca)
  09165 Substance dependence
   05031 Amphetamine addiction
    117706625 (Ppp3ca)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    117706625 (Ppp3ca)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:anu01009]
    117706625 (Ppp3ca)
Enzymes [BR:anu01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     117706625 (Ppp3ca)
Protein phosphatases and associated proteins [BR:anu01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     117706625 (Ppp3ca)
SSDB
Motif
Pfam: Metallophos
Other DBs
NCBI-GeneID: 117706625
NCBI-ProteinID: XP_034355386
LinkDB
Position
4:113072242..113348551
AA seq 521 aa
MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESV
ALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYV
DRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMD
AFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFG
NEKTQEHFTHNTVRGCSYFYSYPAVCDFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFP
SLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEK
VTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESV
LTLKGLTPTGMLPSGVLSGGKQTLQSATVEAIEADEAIKGFSPQHKITSFEEAKGLDRIN
ERMPPRRDAMPSDANLNSINKALASETNGTDSNGSNSSNIQ
NT seq 1566 nt   +upstreamnt  +downstreamnt
atgtccgagcccaaggcgattgatcccaagttgtcgacgaccgacagggtggtgaaagct
gttccatttccgccaagtcaccggctgacagcaaaggaagtgtttgataacgatgggaag
cctcgtgtggatatcttaaaagcacatctcatgaaggagggcaggctggaagaaagcgtc
gcattgagaataataacagagggtgcttcgattctccgacaggaaaaaaacttgctggat
atcgacgccccagtcacagtttgtggggacatccatggacaattctttgacttgatgaag
ctctttgaagtgggaggatctcctgccaacactcgctacctcttcttaggggactatgtt
gacagagggtacttcagtattgaatgtgtgctgtatttgtgggccttgaaaattctttac
cccaaaacactgtttttacttcgcggaaatcatgaatgtaggcacctcacagagtatttc
acgtttaaacaagaatgtaaaataaagtattcagaacgcgtttatgatgcctgtatggat
gcctttgactgccttcccctggccgcgctgatgaaccaacaattcctgtgtgtacatggt
ggtttgtctccagagattaacactctagatgacatcagaaaattagaccgattcaaagaa
ccacctgcttacgggcccatgtgtgacatcctgtggtcagaccccctggaggactttgga
aatgagaagactcaggaacatttcactcacaacacagtcaggggctgctcgtacttctac
agttacccggctgtatgtgacttcctgcagcacaataatttgttgtccatactccgagcc
cacgaagcccaggatgcagggtaccgcatgtacaggaaaagccaaacaacaggcttccca
tctctaattacaatcttctcggcaccaaattacttagatgtgtacaataacaaagctgca
gtgttgaagtacgagaacaatgtgatgaacatcaggcagttcaactgctccccccatccg
tactggctcccaaatttcatggatgttttcacctggtcgctgccgtttgttggggagaaa
gtgaccgagatgctggtaaatgtcctcaacatctgctcagatgatgaactggggtcagaa
gaagatggatttgacggagccacggctgcagcccggaaggaggtcatcaggaacaagatc
cgagcaataggcaaaatggccagagtgttctcagttctcagagaagagagtgagagtgtt
ctgacactgaagggcctgaccccgactggcatgctccccagtggagtgctctctggcgga
aaacaaactctgcaaagcgctactgttgaggctattgaggctgatgaagctatcaaagga
ttttcaccacaacataagatcactagcttcgaggaggccaagggcttagaccgaattaac
gagaggatgccgcctcgcagagacgccatgccctccgacgcaaaccttaactccatcaac
aaggctctcgcctcagagactaacggcacggacagcaatggcagtaatagcagcaatatt
cagtga

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