Arvicanthis niloticus (African grass rat): 117709127
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Entry
117709127 CDS
T08817
Symbol
Jak1
Name
(RefSeq) tyrosine-protein kinase JAK1
KO
K11217
Janus kinase 1 [EC:
2.7.10.2
]
Organism
anu
Arvicanthis niloticus (African grass rat)
Pathway
anu01521
EGFR tyrosine kinase inhibitor resistance
anu04151
PI3K-Akt signaling pathway
anu04217
Necroptosis
anu04380
Osteoclast differentiation
anu04550
Signaling pathways regulating pluripotency of stem cells
anu04620
Toll-like receptor signaling pathway
anu04621
NOD-like receptor signaling pathway
anu04630
JAK-STAT signaling pathway
anu04658
Th1 and Th2 cell differentiation
anu04659
Th17 cell differentiation
anu05140
Leishmaniasis
anu05145
Toxoplasmosis
anu05152
Tuberculosis
anu05160
Hepatitis C
anu05161
Hepatitis B
anu05162
Measles
anu05163
Human cytomegalovirus infection
anu05164
Influenza A
anu05165
Human papillomavirus infection
anu05166
Human T-cell leukemia virus 1 infection
anu05167
Kaposi sarcoma-associated herpesvirus infection
anu05168
Herpes simplex virus 1 infection
anu05169
Epstein-Barr virus infection
anu05171
Coronavirus disease - COVID-19
anu05200
Pathways in cancer
anu05203
Viral carcinogenesis
anu05212
Pancreatic cancer
anu05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
anu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
117709127 (Jak1)
04151 PI3K-Akt signaling pathway
117709127 (Jak1)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
117709127 (Jak1)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
117709127 (Jak1)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
117709127 (Jak1)
04621 NOD-like receptor signaling pathway
117709127 (Jak1)
04658 Th1 and Th2 cell differentiation
117709127 (Jak1)
04659 Th17 cell differentiation
117709127 (Jak1)
09158 Development and regeneration
04380 Osteoclast differentiation
117709127 (Jak1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
117709127 (Jak1)
05203 Viral carcinogenesis
117709127 (Jak1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
117709127 (Jak1)
09162 Cancer: specific types
05212 Pancreatic cancer
117709127 (Jak1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
117709127 (Jak1)
05161 Hepatitis B
117709127 (Jak1)
05160 Hepatitis C
117709127 (Jak1)
05171 Coronavirus disease - COVID-19
117709127 (Jak1)
05164 Influenza A
117709127 (Jak1)
05162 Measles
117709127 (Jak1)
05168 Herpes simplex virus 1 infection
117709127 (Jak1)
05163 Human cytomegalovirus infection
117709127 (Jak1)
05167 Kaposi sarcoma-associated herpesvirus infection
117709127 (Jak1)
05169 Epstein-Barr virus infection
117709127 (Jak1)
05165 Human papillomavirus infection
117709127 (Jak1)
09171 Infectious disease: bacterial
05152 Tuberculosis
117709127 (Jak1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
117709127 (Jak1)
05140 Leishmaniasis
117709127 (Jak1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
117709127 (Jak1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
anu01001
]
117709127 (Jak1)
Enzymes [BR:
anu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
117709127 (Jak1)
Protein kinases [BR:
anu01001
]
Non-receptor tyrosine kinases
JAK family [OT]
117709127 (Jak1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
Jak1_Phl
SH2_1
FERM_F1
ABC1
RIO1
SH2
FERM_C_FAK1
Motif
Other DBs
NCBI-GeneID:
117709127
NCBI-ProteinID:
XP_034359145
LinkDB
All DBs
Position
5:50117920..50229318
Genome browser
AA seq
1153 aa
AA seq
DB search
MQYLNIKEDCNAMAFCAKMRSFKKTEVKQVVPEPGVEVTFYLLDREPLRLGCGEYTAEEL
CIRAAQECSISPLCHNLFALYDESTKLWYAPNRIITVDDKMSLRLHYRMRFYFTNWHGTN
DNEQSVWRHSPKKQKNGYEKKRVPEATPLLDASSLEYLFAQGQYDLIKCLAPIRDAKTEQ
DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENELS
RCHSNDSGNVLYEVMVTGNLGIQWRQKPNVVPVEKEKNKLKRKKLEYNKHKKDEERNKLR
EEWNNFSYFPEITHIVIKESVVSINKQDNKNMELKLASHEEALSFVSLVDGYFRLTADAH
HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
CFEKSEVLGGQKQFKNFQIEVQKGRYSLHGSVDHFPSLRDLMNHLKKQILRTDNISFVLK
RCCQPKPREISNLLVATKKAQEWQPVYSMSQLSFDRILKKDIIQGEHLGRGTRTHIYSGT
LLDYKDDEGIAEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDV
ENIMVEEFVEGGPLDLFMHRKSDALTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLL
LAREGIDSDIGPFIKLSDPGIPVSVLTRQECIERIPWIAPECVEDSKNLSVAADKWSFGT
TLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPSQRPFFRAI
MRDINKLEEQNPDIVSEKQPTTEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNT
GEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICMEDGGNGIKLIMEFLPS
GSLKEYLPKNKNKINLKQQLKYAIQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGD
FGLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDSD
FSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRTT
FQNLIEGFEALLK
NT seq
3462 nt
NT seq
+upstream
nt +downstream
nt
atgcagtatctaaatataaaagaggactgcaatgccatggctttctgtgctaaaatgagg
agcttcaagaagactgaggtgaagcaggtggttcctgagccaggagtggaggtgactttc
tatctgttggacagggagccactccgcctgggctgcggagagtataccgccgaggagctg
tgcatcagggctgcccaggagtgcagtatctctcctctctgtcacaacctcttcgccctg
tacgatgagagcaccaagctctggtacgctccgaaccgaatcatcactgtggatgacaaa
atgtctctccggctccactaccgcatgaggttctactttaccaactggcatggaaccaat
gacaatgaacagtctgtatggcgacattctccaaagaagcagaaaaacggctatgagaag
aaaagggttccagaagcaaccccactccttgatgccagttcactggagtatctgtttgct
cagggacagtatgatttgatcaaatgcctggctcccatccgggacgccaagacggagcag
gatggacatgatattgagaatgagtgcctggggatggctgtcttggccatctcacactat
gccatgatgaagaagatgcagctgccagaacttcccaaggacatcagctacaagagatat
attccagaaacattgaataaatccatcagacagaggaaccttcttaccaggatgcgaata
aataatgttttcaaggatttcttgaaggaatttaacaacaagaccatctgtgacagcagt
gtgtctacacatgacctgaaggtgaaatacctggcaacattggaaactttgacaaaacat
tatggagctgaaatttttgagacttctatgctactgatttcatcagaaaatgaattgagt
cggtgccattcaaatgacagtggcaatgttctctatgaagtcatggtgactggaaatctc
gggatccagtggcggcagaaaccaaatgttgttcctgttgaaaaggaaaaaaataaactg
aagcggaagaaactggaatataataaacacaagaaggatgaggagagaaacaaactccgg
gaagagtggaacaacttttcctatttccccgaaatcacccacattgtaataaaggagtct
gtggtcagcattaacaaacaggacaacaaaaatatggaactaaagctcgcttctcatgag
gaagccctgtcctttgtgtccctggtggatggctacttccggctcactgcagatgcccac
cattacctctgtactgatgtggctcccccactgattgtccacaatatacagaatggctgt
catggtccgatctgcacagaatatgccatcaataagctgcggcaagaagggagtgaggag
ggaatgtatgtgctgaggtggagctgcactgactttgacaacattcttatgactgtcacc
tgcttcgaaaagtctgaggtattgggtggccagaagcagttcaagaactttcagattgag
gtgcagaagggccgctacagcttgcatggctctgttgaccactttcccagcctgagagac
ctcatgaaccacctcaagaagcagatcctgcgcacggacaatataagctttgtgctgaaa
cgttgctgtcagcctaagcctcgagaaatctccaatctgctagtagccactaagaaagcc
caggaatggcagcctgtctactccatgagccagctgagttttgatcggatccttaagaaa
gatattatacaaggcgagcaccttggcagaggcacaagaacacatatctattctgggacc
ctcctggactacaaggatgatgaaggaattgctgaagagaagaagataaaagtgatcctc
aaagtcctagaccccagccaccgggacatttctctggccttctttgaggcagccagcatg
atgagacaggtttcccacaagcacattgtgtacctctatggcgtctgtgttcgagatgtg
gaaaatatcatggtggaagagtttgtggaggggggaccattggatctcttcatgcaccgg
aaaagtgatgcactcaccaccccctggaagttcaaagttgccaaacagctggccagtgcc
ctgagttacctggaagataaagacctggttcacggaaatgtgtgcactaaaaacctcctc
ctggcccgtgagggcattgacagtgacatcggcccattcatcaagcttagtgaccctggc
atcccagtctctgtgctgaccaggcaagagtgcatagagcgaatcccctggattgctcct
gagtgtgttgaagactccaaaaacctgagtgtggctgctgacaagtggagctttggaacc
acactctgggaaatctgctacaatggcgagatccccctcaaagacaagaccctcattgag
aaggaaaggttttatgaaagccgctgcaggcctgtgactccatcttgcaaggagctggcg
gacctcatgactcgttgtatgaactacgatcccagccagagacccttcttccgagccatc
atgagggacattaacaagctggaggagcagaatccagacattgtttcagaaaagcagcca
acaacagaggtggatcccactcattttgaaaagcgtttcctgaagaggattcgtgacttg
ggagagggtcactttgggaaggttgagctctgcagatatgatcctgagggagacaacacg
ggggaacaggtagctgtcaaatccctgaagcctgagagcggaggtaaccacatagctgat
ctgaagaaggagatagagatcttaaggaacctctaccatgagaacattgtgaagtacaaa
ggaatctgcatggaagacggagggaatggtatcaagctcatcatggagttcctgccttcg
ggaagcctaaaggagtatctgccaaagaacaagaacaaaattaacctcaaacagcagcta
aaatatgccatccagatctgtaagggaatggactatttgggttctcggcaatatgttcac
cgggacttagcagcaagaaatgtccttgttgagagtgaacaccaagtgaagattggagac
tttggtttaaccaaagccattgaaactgataaggagtactacacagtcaaggatgaccgg
gacagcccagtgttttggtacgctccggaatgcttaatccagtgtaagttttatatcgcc
tctgatgtctggtcttttggagtgacactgcacgagctgctcacttactgtgactcagat
tttagtcccatggccttgttcctgaaaatgataggcccaactcatggccagatgacagtc
acacggcttgtgaatactctgaaagaaggaaagcgcctgccatgtccacccaactgtcct
gatgaggtttatcagcttatgagaaaatgctgggaattccaaccatctaatcggacaacc
tttcagaaccttattgaaggatttgaagcacttttaaaataa
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integrated database retrieval system
