Arvicanthis niloticus (African grass rat): 117710754
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Entry
117710754 CDS
T08817
Symbol
Ern1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
anu
Arvicanthis niloticus (African grass rat)
Pathway
anu04140
Autophagy - animal
anu04141
Protein processing in endoplasmic reticulum
anu04210
Apoptosis
anu04932
Non-alcoholic fatty liver disease
anu05010
Alzheimer disease
anu05012
Parkinson disease
anu05014
Amyotrophic lateral sclerosis
anu05016
Huntington disease
anu05017
Spinocerebellar ataxia
anu05022
Pathways of neurodegeneration - multiple diseases
anu05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
anu00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
117710754 (Ern1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
117710754 (Ern1)
09143 Cell growth and death
04210 Apoptosis
117710754 (Ern1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
117710754 (Ern1)
05012 Parkinson disease
117710754 (Ern1)
05014 Amyotrophic lateral sclerosis
117710754 (Ern1)
05016 Huntington disease
117710754 (Ern1)
05017 Spinocerebellar ataxia
117710754 (Ern1)
05022 Pathways of neurodegeneration - multiple diseases
117710754 (Ern1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
117710754 (Ern1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
117710754 (Ern1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
anu01001
]
117710754 (Ern1)
Enzymes [BR:
anu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
117710754 (Ern1)
Protein kinases [BR:
anu01001
]
Serine/threonine kinases: Other
IRE family
117710754 (Ern1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
PQQ_2
PQQ
Pkinase_fungal
Kdo
APH
Motif
Other DBs
NCBI-GeneID:
117710754
NCBI-ProteinID:
XP_034361824
LinkDB
All DBs
Position
6:15934432..16024927
Genome browser
AA seq
978 aa
AA seq
DB search
MPARWLLLLLALLLPPPGPGSFGRTSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKE
DPVLQVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSDGILYM
GKKQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNAT
YFDYAASLPEDDVDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLR
KVVHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLMPTLYVGRYSTSLYASPS
MVHEGVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFDPGLKGKSKLNYLRNY
WLLIGHHETPLSASTKMLERFPNNLPKHRENVIPADSDKRSFEEVINLVGQTSDNTPTTV
SQDVEEKMPHAPAKPEAPVDSMLKDMATIILSTFLLVGWVAFIITYPLSMHQQRQLQHQQ
FQKELEKIQLLQQQQQLPFHPHGDLTQDPEFLDSSGLFSESSGTSSPSPSPRASNHSLHS
SSSASKAGTSASLEQDDEDEETRMVIVGKISFCPKDVLGHGAEGTIVYKGMFDNRDVAVK
RILPECFSFADREVQLLRESDEHPNVIRYFCTEKDRQFQYIAIELCAATLQEYVEQKDFA
HLGLEPITLLHQTTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGRIKAMISDFGLCKKLA
VGRHSFSRRSGVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISEGNHPFGKSL
QRQANILLGACSLDCFHSDKHEDVIARELIEKMIAMDPQQRPSAKHVLKHPFFWSLEKQL
QFFQDVSDRIEKEALDGPIVRQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVRD
LLRAMRNKKHHYRELPVEVQETLGSIPDDFVRYFTSRFPHLLSHTYQAMELCRHERLFQT
YYWHEPTEPQPPVISDAL
NT seq
2937 nt
NT seq
+upstream
nt +downstream
nt
atgccggcccggtggctgttgctcctgctggcgctgctgctaccgccccccggccccggg
agttttggaagaaccagcacagtaacactgcctgaaaccttgttgtttgtttcaaccctg
gatggaagtttgcatgctgtcagcaagaggacgggctccatcaagtggactttaaaagaa
gacccagtcctgcaggtcccaacacacgtggaagagcctgctttcctcccagatcccaat
gatggcagtctgtacacacttggaggcaaaaacaacgaaggcctgacgaaactccccttt
accatcccagaattggttcaggcttccccatgccgaagttcagacggaatcctctacatg
ggtaaaaagcaagacatttggtatgttattgacctcctgactggcgagaagcagcagact
ttgtcatcagcctttgccgatagtctctgcccgtcaacttcccttctatatcttggacgc
acagaatataccatcaccatgtatgacaccaagacccgggagctccgctggaatgccacc
tattttgactatgcagcctcactgcctgaagatgacgtggactacaagatgtcccacttt
gtgtccaatggcgatggactggtggtaactgtggacagtgaatctggagatgtcttgtgg
atccaaaactatgcctctcctgtggtggctttctacgtctggcagcgggagggcctgaga
aaggtggtgcacatcaacgttgctgtggagactctacgctacttgaccttcatgtctggg
gaagtggggcgcatcaccaagtggaaatacccattcccgaaggagacagaggccaagagc
aagctcatgcctactctgtatgtggggaggtactccaccagcctatatgcctctccctca
atggttcatgagggggttgctgtcgtgcctcgaggcagcactcttcctttgctggaaggt
ccccagacagatggtgtcaccattggagacaaaggagagtgtgtgatcacccccagcaca
gacctcaagtttgaccctggactcaaagggaagagcaagctgaactacttgaggaattac
tggcttctcataggacaccatgaaactcctctgtctgcatccaccaagatgctggagaga
tttcctaacaacctgcccaaacatcgagaaaatgtgatccctgctgactcggacaaaagg
agctttgaggaagttatcaacctagttggccagacttcagacaacacaccaaccactgta
tcccaggatgtagaagagaagatgccccatgcccctgccaagcctgaggcccctgtggac
tccatgctcaaggacatggccactattatcctgagcaccttcctgcttgttggatgggtg
gcgttcatcatcacttaccccctgagcatgcatcagcagcgccagctccaacaccagcag
ttccagaaggaactggagaaaattcaactcctgcagcagcagcagcagctgcccttccac
ccccatggagaccttacccaggaccctgagttcctggattcctctggcctcttctcagag
agctcaggcaccagcagccccagcccatcccccagagcctccaaccactccctccactcc
agcagctctgcctccaaggccggcaccagtgcctccctggaacaggatgatgaggatgag
gaaaccagaatggtgattgttggaaaaatttcgttctgccccaaggatgtactgggccat
ggagctgagggcacaattgtatacaaaggtatgtttgacaaccgtgatgtggccgtgaag
aggatcctccctgagtgtttcagctttgcagaccgtgaggtccagttgcttcgagaatca
gatgagcacccgaatgtgatccgctacttttgcacagagaaggaccggcagttccagtac
attgccattgaattgtgtgcagctaccctgcaggagtatgtggagcagaaggacttcgcc
caccttggcctagagcccatcaccttgcttcatcagaccacctcaggcctggcacacctg
cattctctcaacattgttcacagagacctgaagccccacaacattctcctctccatgccc
aacgcacatggcaggatcaaggcgatgatctctgactttggcctctgcaagaaactggca
gtgggcaggcacagtttcagccgccgctcaggggtccctggcactgaagggtggatcgcc
ccagagatgctgagtgaagactgcaaggagaaccctacctacacagtggacatcttctct
gcaggctgtgtcttttactacgtcatctctgagggcaaccatccttttggcaaatccttg
cagcggcaggccaacatcctcctgggtgcctgcagccttgactgcttccactcagacaag
cacgaggatgtcattgctcgtgaattgatagagaaaatgattgcaatggatccccagcag
cgaccctctgcaaagcacgtgctaaaacacccattcttctggagcctggaaaagcagctc
cagttcttccaggatgtgagtgaccgaatagaaaaggaggccttagacggcccgatcgtg
cggcagttggagagaggcgggagagctgtggtcaagatggactggcgggagaacatcact
gtccccctgcagacagatctgcgcaaattcagaacctacaaaggtggctctgtcagagat
ctcctccgagccatgagaaataagaaacaccactaccgggagctccctgtggaagttcag
gagacactgggctccatccccgatgactttgtgcgctacttcacgtcccgcttcccccac
ctcctctctcacacctaccaagccatggagctgtgcagacatgagagactcttccagacc
tactactggcacgagcccacagaaccccagcctccagtgatttcagatgccctctga
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