Arvicanthis niloticus (African grass rat): 117711363
Help
Entry
117711363 CDS
T08817
Symbol
Nf1
Name
(RefSeq) neurofibromin isoform X1
KO
K08052
neurofibromin 1
Organism
anu
Arvicanthis niloticus (African grass rat)
Pathway
anu01521
EGFR tyrosine kinase inhibitor resistance
anu04010
MAPK signaling pathway
anu04014
Ras signaling pathway
Brite
KEGG Orthology (KO) [BR:
anu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
117711363 (Nf1)
04014 Ras signaling pathway
117711363 (Nf1)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
117711363 (Nf1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PH_NF1
RasGAP
CRAL_TRIO_2
CRAL_TRIO
MIF4G_like_2
Motif
Other DBs
NCBI-GeneID:
117711363
NCBI-ProteinID:
XP_034362854
LinkDB
All DBs
Position
6:complement(42298477..42538253)
Genome browser
AA seq
2840 aa
AA seq
DB search
MAAHRPVEWVQAVVSRFDEQLPIKTGQQNTHTKVSTEHTKECLINISKYKFSLVISGLTT
ILKNVNNMRIFGEAAEKNLYLSQLIILDTLEKCLAGQPKDTMRLDETMLVKQLLPEICHF
LHTCREGNQHAAELRNSASGVLFSLSCNNFNAVFSRISTRLQELTVCSEDNVDVHDIELL
QYINVDCAKLKRLLKETAFKFKALKKVAQLAVINSLEKAFWNWVENYPDEFTKLYQIPQT
DMAECAEKLFDLVDSFAESTKRKAAVWPLQIILLILCPEIIQDISKDVVDENNINKKLFL
DSLRKALAGHGGSRQLTESAAIACVKLCKASTYINWEDNSVIFLLVQSMVVDLKNLLFNP
SKPFSRGSQPADVDLMIDCLVSCFRISPHNNQHFKICLAQNSPSTFHYVLVNSLHRIITN
SALDWWPKIDAVYCHSVELRNMFGETLHKAVQGCGAHPAIRMAPSLTFKEKVTSLKFKEK
PTDLETRSYKYLLLSMVKLIHADPKLLLCNPRKQGPETQGSTAELITGLVQLVPQSHMPE
VAQEAMEALLVLHQLDSIDLWNPDAPVETFWEISSQMLFYICKKLTSHQMLSSTEILKWL
REILICRNKFLLKNKQADRSSCHSLYLYGVGCDVPASVSTTQMSVDHDEFLRTCTPGASL
RKGKGNSSMDSTAGCSGTPPICRQAQTKLEVALYMFLWSPDTEAVLVAMSCFRHLCEEAD
IRCGVDEVSVHNFLPNYNTFMEFASVSNMMSTGRAALQKRVMALLRRIEHPTAGNTEAWE
DTHAKWEQATKLILNYPKAKMEDQAAESLHKTIVKRRMSHVSGGGSIDLSDTDSLQEWIN
MTGFLCALGGVCLQQRSSSGLATYSPPMGPVSERKGSMISVMSSEGNVDSPVSRFMDRLL
SLMVCNHERVGLQIRTNVKDLVGLELSPALYPMLFNKLKNTISKFFDSQGQVLLTDSNTQ
FVEQTIAIMKNLLDNHTEGSSEHLGQASIETMMLNLVRYVRVLGNMVHAIQIKTKLCQLV
EVMMARRDDLSFCQEMKFRNKMVEYLTDWVMGTSNQAADDDVKCLTRDLDQASMEAVVSL
LAGLPLQPEEGDGVELMEAKSQLFLKYFTLFMNLLNDCSEVEDENAQTGGRKRGMSRRLA
SLRHCTVLAMSNLLNANVDSGLMHSIGLGYHKDLQTRATFMEVLTKILQQGTEFDTLAET
VLADRFERLVELVTMMGDQGELPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLWN
MFSKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYLQKLLDPLLRIIITSSDWQHVSF
EVDPTRLEPSESLEENQRNLLQMTEKFFHAIISSSSEFPSQLRSVCHCLYQATCHSLLNK
ATVKEKKENKKSVVSQRFPQNSIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERGL
KLMSKVLQSIANHVLFTKEEHMRPFNDFVKSNFDLARRFFLDIASDCPTSDAVNHSLSFI
SDGNVLALHRLLWNNQEKIGQYLSSNRDHKAVGRRPFDKMATLLAYLGPPEHKPVADTHW
SSLNLTSSKFEEFMTRHQVHEKEEFKALKTLSIFYQAGTSKAGNPIFYYVARRFKTGQIN
GDLLIYHVLLTLKPYYAKPYEIVVDLTHTGPSNRFKTDFLSKWFVVFPGFAYDNVSAVYI
YNCNSWVREYTKYHERLLTGLKGSKRLIFIDCPGKLAEHIEHEQQKLPAATLALEEDLKV
FHNALKLAHKDTKVSIKVGSTAVQVTSAERTKVLGQSVFLNDIYYASEIEEICLVDENQF
TLTIANQGTPLTFMHQECEAIVQSIIHIRTRWELSQPDSIPQHTKIRPKDVPGTLLNIAL
LNLGSSDPSLRSAAYNLLCALTCTFNLKIEGQLLETSGLCIPANNTLFIVSISKTLAANE
PHLTLEFLEECISGFSKSSIELKHLCLEYMTPWLSNLVRFCKHNDDAKRQRVTAILDKLI
TMTINEKQMYPSIQAKIWGSLGQITDLLDVVLDSFIKTSATGGLGSIKAEVMADTAVALA
SGNVKLVSSKVIGRMCKIIDKTCLSPTPTLEQHLMWDDIAILARYMLMLSFNNSLDVAAH
LPYLFHVVTFLVATGPLSLRASTHGLVINIIHSLCTCSQLHFSEETKQVLRLSLTEFSLP
KFYLLFGISKVKSAAVIAFRSSYRDRSFSPGSYERETFALTSLETVTEALLEIMEACMRD
IPTCKWLDQWTELAQRFAFQYNPSLQPRALVVFGCISKRVSHGQIKQIIRILSKALESCL
KGPDTYNSQVLIESTVIALTKLQPLLNKDSPLHKALFWVAVAVLQLDEVNLYSAGTALLE
QNLHTLDSLRIFNDKSPEEVFMAIRNPLEWHCKQMDHFVGLNFNSNFNFALVGHLLKGYR
HPSPAIVARTVRILHTLLTLVNKHRNCDKFEVNTQSVAYLAALLTVSEEVRSRCSLKHRK
SLLLTDISMENVPMDTYPIHHGDPSYRTLKENQPWSPPKGSEGYLAATYPAVGQTSPRAR
KSMSLDMGQPSQANTKKLLGTRKSFDHLISDTKAPKRQEMESGITTPPKMRRVAETDYEM
ETQRISSPQQHPHLRKVSVSESNVLLDEEVLTDPKIQALLLTVLATLVKYTTDEFDQRIL
YEYLAEASVVFPKVFPVVHNLLDSKINTLLSLCQDPNLLNPIHGIVQSVVYHEECPPQYQ
TSYLQSFGFNGLWRFAGPFSKQTQIPDYAELIVKFLDALIDTYLPGIDEETSEESLLTPT
SPYPPALQSQLSITANLNLSNSMTSLATSQHSPGIDKENVELSPTTGHCNSGRTRHGSAS
QVQKQRSAGSFKRNSIKKIV
NT seq
8523 nt
NT seq
+upstream
nt +downstream
nt
atggccgcacacaggccggtggaatgggtccaggccgtggtcagccgcttcgacgagcag
cttccaataaaaacaggacagcagaacacacataccaaagtcagcaccgagcacaccaag
gagtgtctgatcaacatttccaaatacaagttttctttggtcatcagtgggctcaccacc
atcctaaagaatgttaacaatatgaggatatttggagaagctgctgaaaaaaatttgtat
ctctctcagttgatcatattggacacactggaaaaatgtcttgctgggcaaccaaaggac
acaatgagattagatgaaacaatgctggttaaacagttactaccagaaatctgccatttt
cttcatacctgccgtgaaggaaaccaacatgccgccgaacttcggaattctgcttctggg
gttttattttctctgagctgcaacaacttcaatgcagtctttagtcgcatttctacaagg
ttacaagagttgactgtctgttcagaagacaatgtcgatgttcatgatatagaattgtta
cagtatattaatgtggattgtgcaaaattaaaacgactcctgaaggaaacagcatttaaa
tttaaagccctgaagaaggtcgcacagttggcagttataaatagcctagaaaaggctttt
tggaactgggtagaaaattatccggatgaatttacaaagctataccaaattccacagaca
gatatggctgagtgtgcagaaaagctgtttgacttggtggatagttttgcagaaagcacc
aaacgtaaagcagcagtttggccactacaaatcattctccttattttgtgtcctgaaata
atccaggacatatccaaggatgtggttgatgagaacaacataaacaagaagctgtttctg
gacagtttacgaaaagcacttgctggccatggaggaagcagacagctgactgaaagtgct
gccattgcttgtgtcaagttgtgtaaagcaagtacttacatcaactgggaagataactct
gtcattttcctactagttcagtccatggtggttgatcttaagaacctgctttttaatcca
agtaaaccattctctagaggcagtcagcctgcagatgtggacctcatgattgactgtctt
gtctcttgctttcggataagccctcacaacaaccaacactttaagatctgcctggctcag
aattcaccttctacatttcactatgtgttggtaaactcactccaccgcatcatcaccaat
tctgcgttggattggtggcctaagattgatgctgtgtattgtcactcagttgaacttcga
aatatgtttggtgaaacacttcataaagcagtgcaaggctgtggagcgcacccagcaata
agaatggcgccaagtctcacctttaaagaaaaggtaacaagccttaaatttaaagaaaag
cctacagacctagagacaaggagctacaagtatcttcttttgtccatggtgaaactgatc
catgcagacccaaagcttctgctttgtaatccaagaaaacagggtcctgaaactcaaggc
agtacagcagaactaattacagggctcgtacaactggtgcctcagtcacacatgccagag
gtcgcacaggaggctatggaggctttgctggttcttcatcagttagatagcatcgattta
tggaatcctgatgctcctgtagaaacattttgggaaattagttcacaaatgcttttttac
atctgcaagaagttaactagccatcaaatgcttagtagcacagaaattctcaagtggtta
cgggaaattctgatctgcagaaataaatttcttcttaaaaataagcaggcagatagaagt
tcctgtcattctctctacctttatggagtaggatgtgatgtacctgctagtgtaagtacc
actcagatgtcagttgatcatgatgagttcctacggacctgtactcctggagcatctctg
cggaaaggaaaaggaaattcctccatggatagcacagcagggtgcagtggaaccccacct
atatgccgacaagcccagaccaagctagaagtggccttgtatatgtttctgtggagtcct
gacactgaagctgttctggttgctatgtcctgtttccgccacctctgtgaagaagcagat
atccgatgtggggtggatgaagtgtcagtgcacaacttcttgcccaattataacacattc
atggaatttgcctcagtcagcaatatgatgtcaacaggaagagcggcacttcagaaaaga
gtgatggccctgctaaggcgcattgagcaccctactgcaggaaacactgaggcctgggaa
gatacacatgcaaagtgggaacaggctacaaagctaatccttaactacccaaaagccaaa
atggaagaccaggctgcagaaagtcttcataagaccattgttaaaagacggatgtcccat
gtcagtggaggaggatccatagacttgtctgacacagactccctacaggaatggatcaac
atgactggcttcctttgtgcccttggtggggtgtgcctgcaacagagaagcagctctggc
ctagcgacatacagcccacctatgggcccagtcagtgaacgcaaagggtctatgatttct
gtaatgtcttctgaagggaatgttgattcacctgtcagcagatttatggaccggcttctg
tccttaatggtgtgtaaccatgagagagtggggcttcagatacggaccaatgttaaggac
ctggtgggtctggaattgagtcctgctctgtatccaatgttgtttaacaaactgaagaat
accatcagcaagttttttgactctcaaggacaggtattattaactgacagcaatactcag
tttgtagagcaaaccatagccataatgaaaaacctactggataatcatactgaaggcagc
tctgagcatctgggacaagcaagcattgagacaatgatgctaaatctggtcagatacgtt
cgtgttcttgggaatatggtccatgcaatacaaataaaaacaaaattgtgtcagttagtt
gaagtcatgatggcaagaagagacgacctctcattttgtcaagagatgaaatttaggaat
aagatggtagaatacctaacagactgggttatggggacatcaaaccaagcagcagatgat
gatgtaaaatgtcttacaagagatttggaccaagcaagcatggaagcagtagtttcactc
ctcgctggtcttccactgcagcctgaagaaggagatggggtggagctgatggaggccaaa
tcacagttattccttaagtacttcacattatttatgaaccttttgaatgactgtagtgaa
gttgaagatgaaaatgcacaaacaggtggcaggaaacgtggcatgtctaggaggctggca
tccctgaggcactgtacagtgcttgcaatgtcaaacttactcaatgctaatgtggacagt
ggactcatgcactccataggcttagggtatcacaaggatcttcagacaagagctacattc
atggaagttctgaccaaaatccttcaacaaggaacagaattcgatacacttgctgaaacg
gtgttggcagatcggtttgagagacttgtggaactggtcacaatgatgggagatcaggga
gaactccctatagctatggctctggctaatgtggtcccttgttctcagtgggatgagctg
gctcgcgttctggtcactctgtttgactcccggcatttactctaccagctgctctggaac
atgttttctaaggaggtagaattggcagactccatgcagactctttttcgaggcaacagc
ttggccagtaagataatgacattctgcttcaaggtgtatggtgctacttaccttcaaaag
ctcttggaccctttattacgaatcattatcacatcttctgattggcaacatgttagcttt
gaagtggatcctaccaggttagaaccctctgagagccttgaggagaaccagaggaacctc
cttcagatgacagagaagttcttccatgccatcatcagctcttcctcagaattcccctcg
cagcttcgaagtgtctgccattgtttgtaccaggcaacttgccactccctactgaataaa
gctacagtaaaagaaaaaaaggaaaacaaaaaatcagtggttagccagcgcttccctcag
aacagcatcggtgcagtaggaagtgccatgttcctcagattcatcaatcctgccatcgtc
tcaccatatgaagcagggattttagataaaaagccgccaccaagaattgaaaggggcttg
aagttaatgtcaaaggtacttcagagcattgccaatcatgtactattcacaaaagaagaa
catatgaggccttttaatgattttgtgaaaagcaactttgacttggcacgaaggtttttc
ctagatatagcatcagattgtcctacaagtgatgccgtaaaccatagtctttctttcatc
agtgatggcaatgtgcttgctttacatcggctgctttggaacaatcaggagaaaattggc
cagtatctttccagcaacagggatcataaagctgttggaagaagaccttttgataagatg
gccacacttcttgcatacctgggtcctccggagcacaaacctgtggcagatacacattgg
tccagccttaaccttaccagttcaaagtttgaggaatttatgaccaggcaccaagtacat
gagaaggaagagttcaaggccttgaaaacgttaagcatcttctaccaagctggcacctct
aaagctgggaatcctattttttattatgttgcacggaggttcaaaactggccaaatcaat
ggtgatttgctgatataccatgtcttgctgactttaaagccatattatgcaaagccatat
gaaatcgtagtggaccttacccatactgggcctagcaatcgctttaaaacagacttcctc
tctaagtggtttgttgttttccctggctttgcatacgacaacgtctctgcagtgtatatc
tataactgtaactcctgggtcagggagtataccaagtaccatgagcggctgctgactggc
ctcaagggcagcaaaaggctcattttcatcgactgtcctgggaagctagctgagcacata
gagcacgagcagcagaaactccctgctgctaccttggctttggaagaagatctgaaggtt
ttccacaatgctctcaagctagctcacaaggacaccaaagtttctattaaggttggttct
actgctgttcaggtaacctcagcagaaagaacaaaagttttggggcaatccgtcttttta
aatgatatctactatgcttctgaaatcgaagagatctgcctagttgatgagaaccagttc
actttaaccatcgcaaaccaaggcacacctctgaccttcatgcaccaagaatgtgaagcc
attgttcagtctatcattcatatcaggacccgctgggagctgtcacagcctgactccatc
cctcagcataccaagattcgaccaaaagatgtccctgggacactgcttaatattgcatta
ctgaatttgggcagttcagaccctagtttacgatctgctgcctataatctcctgtgtgcc
ttaacctgcacctttaatttgaagattgaaggtcagttacttgagacatcagggttatgc
atccctgccaacaacacactcttcattgtctccatcagtaagacacttgcagccaatgag
ccacacctcaccttagagtttttggaagagtgtatttctggatttagcaaatctagtatt
gaattgaagcacctttgtttggaatatatgaccccatggctatcaaatctagtccgtttt
tgtaagcataatgatgatgccaaacgacagagggttactgccatccttgataagctaata
acaatgaccataaacgagaagcagatgtacccttctattcaagcaaaaatctgggggagc
cttgggcagatcacagacctgctagatgttgtgcttgacagtttcatcaaaaccagtgcg
acaggagggttagggtctatcaaagctgaggtgatggcagacacggctgtggctttagct
tctggaaatgtgaagttggtgtcgagtaaggttattggaaggatgtgtaaaataattgac
aagacttgcttgtctccgactccaactttagaacaacatcttatgtgggacgatattgcc
attttagcccgttacatgctgatgctgtccttcaataactccctggatgtggcagctcat
cttccctatctcttccatgttgtcactttcttagtagccacaggtcccttgtcccttcgt
gcttccacacatggattggttattaatatcattcactccctgtgtacttgttcacagctt
cattttagtgaagagaccaagcaagttttgaggctcagtctaacagagttctcattaccc
aaattttacttactgtttggcattagcaaagtcaagtcagccgctgttattgccttccgt
tcaagttaccgggaccggtcattctcccctggctcctatgagagggagacttttgctttg
acatctctggaaacagtcacagaagctttgttggagatcatggaggcatgtatgagagat
attccaacatgcaagtggcttgatcagtggacagaactggctcaaagatttgcgtttcag
tacaacccatccctgcaaccaagagctcttgtggtgtttggctgtattagcaaacgtgta
tctcatgggcagataaagcagattatccgaattcttagcaaggcacttgaaagttgttta
aaaggacctgacacttacaacagtcaagttctgatagaatctacggtgatagcactgaca
aaattacagccgcttcttaataaggactcgccgctgcacaaagccctcttttgggttgcc
gtggctgtgctgcagctggacgaggtcaacttgtattcagctggcactgctcttctggaa
caaaacctgcacaccttggatagtcttcggatattcaatgacaagagtccagaagaagta
tttatggcaatccggaatcctctggaatggcactgcaaacaaatggatcactttgttgga
ctcaacttcaactctaattttaactttgcactagttggacacctcttaaaagggtacagg
catccttcacctgccattgttgcaagaacagtcagaattttgcatacactactaactctc
gttaacaaacatagaaattgtgacaaatttgaggtgaatacacagagtgtggcttactta
gcagcgctactcacagtgtctgaagaggttcgaagtcgctgtagcctcaagcataggaaa
tcccttcttcttactgatatttcaatggaaaatgttcctatggatacatatcccattcat
catggtgaccccagctataggacactaaaggagaaccagccatggtcccctcccaaaggt
tcagaaggataccttgcagccacctacccagctgtaggccagaccagtccccgtgccagg
aaatccatgagcttggacatgggacagccttctcaggctaacaccaaaaaattgcttgga
acaagaaaaagttttgaccacttgatatcagacacaaaggctcctaaaagacaagaaatg
gaatcagggattacaacacccccaaaaatgagaagagtggcagagactgattatgaaatg
gaaacccaaaggatttcctccccgcagcagcacccacatttacggaaagtctcagtgtct
gaatcaaatgttctgctggatgaagaagtacttactgacccaaagatccaagcactgctt
cttactgttctggctacactggtaaagtatactacagatgaatttgatcaacgaattctt
tatgaatatctagcagaggccagtgttgtgtttcccaaagtgtttcctgttgtgcacaat
ttgttggactctaagatcaataccctcttgtctttgtgccaagatccaaatttgttaaat
ccaatccatggaattgtgcagagtgtggtgtaccatgaggaatgccctccacagtaccaa
acatcttacctgcaaagttttggttttaatggcttatggaggtttgcagggcccttttcg
aagcaaacacaaatcccagactatgctgagctcattgttaaatttcttgatgccttgatt
gacacgtacttgcctggaattgatgaagaaaccagtgaggagtccctcctgacacccaca
tctccttaccctcctgcactgcagagccagcttagtatcactgccaaccttaacctctct
aattccatgacctcacttgcaacttcccagcattccccaggaatcgacaaggagaacgtt
gaactctcccccaccactggccactgtaacagtggacggactcgccatggatccgcaagc
caagtgcagaagcaaagaagtgctggcagtttcaaacgtaatagcattaagaagatcgtg
tga
DBGET
integrated database retrieval system
