Arvicanthis niloticus (African grass rat): 117712805
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Entry
117712805 CDS
T08817
Symbol
Gclc
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
anu
Arvicanthis niloticus (African grass rat)
Pathway
anu00270
Cysteine and methionine metabolism
anu00480
Glutathione metabolism
anu01100
Metabolic pathways
anu01240
Biosynthesis of cofactors
anu04216
Ferroptosis
Module
anu_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
anu00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
117712805 (Gclc)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
117712805 (Gclc)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
117712805 (Gclc)
Enzymes [BR:
anu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
117712805 (Gclc)
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Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
117712805
NCBI-ProteinID:
XP_034364846
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Position
7:11091272..11125370
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AA seq
637 aa
AA seq
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MGLLSQGSPLSWEETQRHADHVRRHGILQFLHIYHAVKDRHKDVLKWGDEVEYMLVSFDH
ENRKVQLLLNGGDVLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EDNMRKRRKEATSVLGEHQALCTITSFPRLGCPGFTLPEYRPNPEEGGASKSLFFPDEAI
NKHPRFGTLTRNIRHRRGEKVVINVPIFKDKRTPSPFVETFPEDEEASKASKADHIYMDA
MGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGVI
SASVDDRTREERGLEPLKNNRFRISKSRYDSIDSYLSKCGEKYNDIDLTIDKEIYEQLLE
EGIDHLLAQHVAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSDI
GWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAVL
QGMFYFRKDICKGGNAVVDGCSKAQTSSEPAAEEYALMSIDTIINGKEGLFPGLIPILNS
YLENMEVDVDTRCSILNYLKLIKKRASGELMTVAKWMREFIANHPDYKQDSVITDEINYS
LILKCNQIANELCECPELLGSGFRKAKYSGGKSDPSN
NT seq
1914 nt
NT seq
+upstream
nt +downstream
nt
atggggctgctgtcccaaggctcgccactgagctgggaagagacccagcgccacgccgac
cacgtgcggaggcacggcatcctccagttcctgcacatctaccacgcagtcaaggaccgg
cacaaggacgtgctcaagtggggtgacgaggtggaatacatgttggtgtcctttgatcat
gaaaatagaaaagtccagttgttactgaatggaggagatgttcttgaaactctgcaggag
aagggggagaggacaaaccccaaccacccaaccctctggagaccggagtatgggagttac
atgatcgaagggacacctggtcagccctatggaggaacgatgtctgagttcaacactgtg
gaggacaacatgaggaaacgccggaaggaggctacttctgtattaggagaacatcaggct
ctttgcactataacctcatttcccagactaggctgtcctggatttacactgccagagtac
agacccaacccagaggaaggaggcgcatctaagtccctgttctttccagatgaagccata
aacaagcacccccgcttcggtactctaacaagaaacatccggcataggagaggagaaaag
gttgtcatcaatgtgccaatattcaaggataagcgtacaccgtctccatttgtagaaacg
tttcctgaagatgaggaggcatcaaaggcttctaaggcagaccatatctacatggatgcc
atgggatttgggatgggcaactgctgtcttcaggtgacattccaagcctgcagcatatct
gaggcaagatacctttatgatcagctggccactatctgcccaattgttatggctttgagt
gctgcatctccattctaccgaggctacgtgtcagacattgattgtcgttggggagtgatt
tctgcatctgtagatgatagaacacgggaggagagaggactggagcctctgaagaacaat
cgctttaggatcagtaagtctcggtatgactccatagatagctacctgtctaagtgtggt
gagaagtacaatgacattgacctgaccatcgataaggaaatctatgagcagctcttggag
gaaggcatcgatcatcttctggcacagcatgttgctcatctctttattagagacccactc
actctttttgaagagaaaatacacctggatgatgccaacgagtctgaccattttgagaat
attcagtccacaaactggcagacaatgaggtttaagcctcctcctcccaactcagacatt
ggatggagagtagagttccgaccgatggaggtgcagttaacagactttgagaactctgcc
tatgtggtatttgtggtactgctcaccagggtgatcctttcatacaaactagacttcctc
attccactgtccaaggttgacgagaacatgaaagtggcacagaagcgagatgctgtcttg
cagggaatgttttacttcaggaaagacatttgcaaaggtggcaacgctgtggtggatggg
tgtagcaaggcccagaccagctccgagccagctgcagaggagtacgctctgatgagcata
gacaccatcatcaacgggaaggaagggctgtttcccggactcatccccattctgaactcc
tatcttgagaacatggaagtcgatgtggacacccgatgcagtattctgaactacctaaag
ctaattaagaagagagcatctggagaactaatgactgttgccaagtggatgagagagttc
attgcaaaccatcctgactacaagcaagatagtgtaataactgatgagatcaactatagc
ctcattttgaaatgcaaccaaattgcaaatgagttgtgtgaatgtccagagttacttgga
tcaggatttagaaaagcaaaatatagtggaggtaaaagtgacccttccaactag
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