Arvicanthis niloticus (African grass rat): 117713684
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Entry
117713684 CDS
T08817
Symbol
Tyk2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
anu
Arvicanthis niloticus (African grass rat)
Pathway
anu04217
Necroptosis
anu04380
Osteoclast differentiation
anu04620
Toll-like receptor signaling pathway
anu04621
NOD-like receptor signaling pathway
anu04630
JAK-STAT signaling pathway
anu04658
Th1 and Th2 cell differentiation
anu04659
Th17 cell differentiation
anu05145
Toxoplasmosis
anu05160
Hepatitis C
anu05161
Hepatitis B
anu05162
Measles
anu05164
Influenza A
anu05165
Human papillomavirus infection
anu05167
Kaposi sarcoma-associated herpesvirus infection
anu05168
Herpes simplex virus 1 infection
anu05169
Epstein-Barr virus infection
anu05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
anu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
117713684 (Tyk2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
117713684 (Tyk2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
117713684 (Tyk2)
04621 NOD-like receptor signaling pathway
117713684 (Tyk2)
04658 Th1 and Th2 cell differentiation
117713684 (Tyk2)
04659 Th17 cell differentiation
117713684 (Tyk2)
09158 Development and regeneration
04380 Osteoclast differentiation
117713684 (Tyk2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
117713684 (Tyk2)
05160 Hepatitis C
117713684 (Tyk2)
05171 Coronavirus disease - COVID-19
117713684 (Tyk2)
05164 Influenza A
117713684 (Tyk2)
05162 Measles
117713684 (Tyk2)
05168 Herpes simplex virus 1 infection
117713684 (Tyk2)
05167 Kaposi sarcoma-associated herpesvirus infection
117713684 (Tyk2)
05169 Epstein-Barr virus infection
117713684 (Tyk2)
05165 Human papillomavirus infection
117713684 (Tyk2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
117713684 (Tyk2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
anu01001
]
117713684 (Tyk2)
Enzymes [BR:
anu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
117713684 (Tyk2)
Protein kinases [BR:
anu01001
]
Non-receptor tyrosine kinases
JAK family [OT]
117713684 (Tyk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
SH2_1
Kdo
Kinase-like
APH
ABC1
Motif
Other DBs
NCBI-GeneID:
117713684
NCBI-ProteinID:
XP_034365985
LinkDB
All DBs
Position
8:86972404..86999050
Genome browser
AA seq
1186 aa
AA seq
DB search
MVTSMPLCGRRATLEDSKADGTEAQPLVPTGHLMVLLHWPGPEGGEPWVTFSQPSLTAEE
VCIHIAHKVGITPPCLNLFALYDAQAKVWLPPNHILDTSQDVSLRLYFRMRFYFRNWHGM
NPHEPAVYRCGFPGAETSSDRAEQGVQLLDSASFEYLFEQGKHEFMNDVVSLRDLSSEEE
IHHFKNESLGMAFLHLCHLALCRGVPLEEMAREISFQNCIPHSFRQHIRQHNVLTRLRLR
RVFRRFLRAFRPGHLSQQVVMVKYLATLERLAPRFGSERIPVCHLEVLAQPERDSCYIQN
SGQTTGDPGPELASGPPTHEVLVTGTGGIQWRLLQTQESERSNSRGNPQGSRSGKKPKAP
EAGERLAESPQELPWTYFCDFQDISHVVLKECRVHIHLQDNKCLLLCLCSQAEALSFVAL
VDGYFRLTADSSHYLCHEVAPPRLVTSIQNGVHGPLMDPFVQAKLWPEDGLYLIQWSTSH
LHRLILTVAHRNPAPRNGPRGLRLRKFPITQQPGAFVLDGWDRSFDNLGDLRLALQGCSL
RAGDDSFPLHHCCLPRPREISNLVIMRGSRAHTQPLNLSQLSFHRVHQDEITQLSHLGQG
TRTNVYEGLLRVGGPDEGKADSGCPPEPGGGSGQQLRVVLKVLDPSHHDIALAFYETASL
MSQVSHMHLAFLHGVCVRGSENIIVTEFVEHGPLDVWLRRQRGRVPMTWKMAVAQQLASA
LSYLEDKNLVHGNVCGRNILLARLGLEEGTNPFIKLSDPGVGQGALSREERVERIPWTAP
ECLSGGASSLGTATDMWGFGATLLEICFDGEAPLQGRGPSEKERFYTKKHQLPEPSCPEL
ATLTRQCLTYEPAQRPSFRTILRDLTRLQPQNLVGTSAVNSDSPASDPTVFHKRYLKKIR
DLGEGHFGKVSLYCYDPNNDGTGEMVAVKALKEGCGPQLRSGWQREIEILRTLYHEHIVK
YKGCCEDQGEKSVHLVMEYVPLGSLRDYLPRHSVGLAQLLLFAQQICEGMAYLHAQRYIH
RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKECKFYYA
SDVWSFGVTLYELLTYCDSTQSPPSKFLELIGLTQGQMAVLRLTELLERGERLPRPDRCP
CEIYHLMKNCWESEASCRPTFQNLVPILKTAQEKYQGQVPSVFSVC
NT seq
3561 nt
NT seq
+upstream
nt +downstream
nt
atggtgacgagcatgcctctgtgtgggcggagagccaccttggaagacagcaaggcagat
ggcacagaagctcagcccctggtgcccacaggacacttgatggtgctgctgcactggcct
gggcctgagggcggggagccctgggtcaccttcagccagccatctctgactgcagaggag
gtctgcatccacatcgcacacaaagtcggcatcactccaccctgcttgaatctctttgcg
ctctacgatgcacaggccaaggtctggctgcccccaaaccacattttggatacatcccaa
gatgtgagcctgaggctctattttcgaatgaggttttacttccggaactggcatggcatg
aatccccatgagccagctgtataccgatgtggcttcccaggggcagagacttcctcagac
cgggccgagcaaggcgtacagctcttggactctgcctcatttgaatacctttttgagcag
ggcaagcatgagttcatgaacgatgtggtgtctctgcgggacctgtctagtgaggaagag
atccaccactttaagaatgagagcctgggcatggcctttctgcacctctgccaccttgct
ctctgccgaggtgtccccctggaggagatggccagagagatcagcttccagaactgcatc
cctcactccttccgccagcacatccgccagcacaatgtgcttacgcgcctgcgtctccgc
agagttttccgccgcttcctgcgggctttccggcctggccacctctcccagcaggttgtg
atggtcaagtacttggccaccctggagcggctggctcctcgctttggctcagagcgcata
cctgtgtgtcatctggaggtcctggcccagcctgagagggactcctgctacatccagaac
agtgggcagaccactggggacccaggcccagagctggcttccgggccccccacccacgag
gtactggtgacaggcaccggaggtatccagtggcgtctactgcagacccaggaatctgag
agaagtaacagcagagggaatcctcaaggcagccgctctgggaagaaacccaaggcccct
gaggctggagagcgcctggcagagagtcctcaggaactaccttggacctacttctgtgac
ttccaggacatttcccacgtggtgttaaaggagtgccgcgtgcacatccaccttcaagac
aacaagtgcttgttgctgtgcctctgttcccaggctgaggccctgtcctttgtggccctg
gtcgatggctatttccgcttgactgctgactccagccactacctgtgccacgaggtggca
cccccgaggctggtgactagcatccagaacggtgtccatgggcctctgatggatccattt
gtacaggccaagctgtggccagaggatggcctctacctgattcagtggagcaccagccac
ctgcaccgcctgatccttactgtggcccatcgaaacccggctcccaggaatggccctagg
ggcctgcgcctccgaaagttccccatcacccagcagcctggagcctttgtgctagatggc
tgggaccgctcctttgacaacttgggggaccttcggctcgccttgcaaggctgctcattg
cgggctggtgatgacagttttcccttgcaccactgctgcctgccccggccaagagaaatc
tccaaccttgtcatcatgcggggatctagggcccacacccagccgctcaacctcagtcag
ctcagcttccacagggttcaccaggatgaaatcacccagctctcccacttgggccaaggc
acaagaaccaatgtgtatgagggcctgctaagagtggggggccccgatgagggcaaagcg
gacagtggatgtccccctgagcctggtgggggcagtgggcagcagcttcgagtggtgctc
aaagtccttgaccccagtcaccatgatatcgccttggccttctatgagactgctagcctc
atgagccaggtgtcacacatgcacctggctttcctgcatggtgtttgcgtgcgtggctca
gagaatatcattgtgacagaattcgtagaacatggtcccctggatgtctggttacggcga
cagaggggccgagtgcccatgacctggaagatggctgtggctcagcagctggccagcgcc
ctcagctacctggaggacaagaatctggttcacgggaacgtatgtgggcggaacatcctg
ctggcccgcctgggactggaggagggtaccaaccccttcatcaagctaagtgatcctggt
gtgggacaaggtgccctctccagggaagagcgggtggaacgcatcccctggacagctcct
gagtgcctgtctggaggggccagtagcttgggtactgccacggacatgtggggctttggt
gccacccttcttgagatctgctttgatggggaggcacccctgcagggtcgtggtccctcc
gagaaagagcgtttctacacaaagaaacatcagctgcctgagccctcatgcccagagctg
gccacgctcacccgccagtgcctgacctatgaaccagcacagcggccctcgtttcgcacc
attttgcgggacctcacaagactgcagccacagaatctagtgggtacttcggctgtgaac
tcagactcaccagcgtcagaccccactgttttccacaagcgttatttgaaaaaaatccgg
gatttgggtgagggtcactttggcaaggtcagcctgtattgctacgatccaaacaatgac
ggcactggtgagatggtggccgtgaaagccctgaaggagggatgtggtccgcagctccgc
tcaggctggcagcgggagatcgaaatcctgcggacgctgtaccatgaacacattgtcaag
tacaaaggctgctgtgaggaccaaggagagaagtctgtacacctggtcatggaatacgtc
cctctgggcagcctccgcgactacctgccaaggcacagcgtagggctggcccagctcctg
ctgtttgcccagcagatctgcgagggcatggcctacttgcatgctcagcgctacattcac
cgagaccttgctgcgcgcaacgtgctgctggacaacgacaggctggtcaagattggagac
tttggcctagccaaggctgtacctgaaggccatgagtactaccgagtgcgcgaggacggg
gacagcccagtgttctggtatgccccagaatgcctgaaggagtgcaaattttactatgca
tctgatgtctggtccttcggggtaaccctgtatgagctgttgacatactgtgactctacg
cagagtcccccctcgaaattccttgagctcatcggcctcacccagggccagatggctgtt
ctgaggctcacagagttgctggaacgaggagagaggctgcctcggcctgacagatgcccc
tgtgagatctatcacctcatgaagaactgctgggagtcagaggcctcctgccgccccacc
ttccagaatcttgtacccatcctcaaaacagcacaggagaagtaccaaggccaggtgcct
tcagtgttcagcgtgtgctga
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integrated database retrieval system
