Arvicanthis niloticus (African grass rat): 117715978
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Entry
117715978 CDS
T08817
Symbol
Igf1r
Name
(RefSeq) insulin-like growth factor 1 receptor
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
anu
Arvicanthis niloticus (African grass rat)
Pathway
anu01521
EGFR tyrosine kinase inhibitor resistance
anu01522
Endocrine resistance
anu04010
MAPK signaling pathway
anu04014
Ras signaling pathway
anu04015
Rap1 signaling pathway
anu04066
HIF-1 signaling pathway
anu04068
FoxO signaling pathway
anu04081
Hormone signaling
anu04114
Oocyte meiosis
anu04140
Autophagy - animal
anu04144
Endocytosis
anu04150
mTOR signaling pathway
anu04151
PI3K-Akt signaling pathway
anu04152
AMPK signaling pathway
anu04211
Longevity regulating pathway
anu04213
Longevity regulating pathway - multiple species
anu04510
Focal adhesion
anu04520
Adherens junction
anu04550
Signaling pathways regulating pluripotency of stem cells
anu04730
Long-term depression
anu04913
Ovarian steroidogenesis
anu04914
Progesterone-mediated oocyte maturation
anu05200
Pathways in cancer
anu05202
Transcriptional misregulation in cancer
anu05205
Proteoglycans in cancer
anu05214
Glioma
anu05215
Prostate cancer
anu05218
Melanoma
anu05224
Breast cancer
anu05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
anu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
117715978 (Igf1r)
04014 Ras signaling pathway
117715978 (Igf1r)
04015 Rap1 signaling pathway
117715978 (Igf1r)
04066 HIF-1 signaling pathway
117715978 (Igf1r)
04068 FoxO signaling pathway
117715978 (Igf1r)
04151 PI3K-Akt signaling pathway
117715978 (Igf1r)
04152 AMPK signaling pathway
117715978 (Igf1r)
04150 mTOR signaling pathway
117715978 (Igf1r)
09133 Signaling molecules and interaction
04081 Hormone signaling
117715978 (Igf1r)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
117715978 (Igf1r)
04140 Autophagy - animal
117715978 (Igf1r)
09143 Cell growth and death
04114 Oocyte meiosis
117715978 (Igf1r)
09144 Cellular community - eukaryotes
04510 Focal adhesion
117715978 (Igf1r)
04520 Adherens junction
117715978 (Igf1r)
04550 Signaling pathways regulating pluripotency of stem cells
117715978 (Igf1r)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
117715978 (Igf1r)
04914 Progesterone-mediated oocyte maturation
117715978 (Igf1r)
09156 Nervous system
04730 Long-term depression
117715978 (Igf1r)
09149 Aging
04211 Longevity regulating pathway
117715978 (Igf1r)
04213 Longevity regulating pathway - multiple species
117715978 (Igf1r)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
117715978 (Igf1r)
05202 Transcriptional misregulation in cancer
117715978 (Igf1r)
05205 Proteoglycans in cancer
117715978 (Igf1r)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
117715978 (Igf1r)
05214 Glioma
117715978 (Igf1r)
05218 Melanoma
117715978 (Igf1r)
05215 Prostate cancer
117715978 (Igf1r)
05224 Breast cancer
117715978 (Igf1r)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
117715978 (Igf1r)
01522 Endocrine resistance
117715978 (Igf1r)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
anu01001
]
117715978 (Igf1r)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
anu04090
]
117715978 (Igf1r)
Enzymes [BR:
anu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
117715978 (Igf1r)
Protein kinases [BR:
anu01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
117715978 (Igf1r)
CD molecules [BR:
anu04090
]
Proteins
117715978 (Igf1r)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Pkinase
Furin-like
fn3
Ig_DSCAM-DSCAML_C
Kinase-like
Insulin_TMD
B2
Motif
Other DBs
NCBI-GeneID:
117715978
NCBI-ProteinID:
XP_034368686
LinkDB
All DBs
Position
1:40366457..40646393
Genome browser
AA seq
1373 aa
AA seq
DB search
MKSGSGGGSPTSLWGLVFLSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGFLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTIDWSLILDAVSNNYIVGNKPPKECGD
LCPGTLEEKPMCEKTTINNEYNYRCWTTNRCQKMCPSVCGKRACTENNECCHPECLGSCH
TPDDNTTCVACRHYYYKGVCVPACPPGTYRFEGWRCVDRDFCANIPNAESSDSDGFVIHD
GECMQECPSGFIRNSTQSMYCIPCEGPCPKVCGDEEKKTKTIDSVTSAQMLQGCTILKGN
LLINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILGEEQLEGNYS
FYVLDNQNLQQLWDWNHRNLTVRSGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINT
RNNGERASCESDVLRFTSTTTWKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYD
GQDACGSNSWNMVDVDLPPNKEGEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKS
EILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPTLPNGNLSYYIVRWQRQPQDGYLYR
HNYCSKDKIPIRKYADGTIDVEEVTENPKTEVCGGDKGPCCACPKTEAEKQAEKEEAEYR
KVFENFLHNSIFVPRPERRRRDVMQVANTTMSSRSRNTTVADTYNITDPEEFETEYPFFE
SRVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVT
WEPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPG
NYTARIQATSLSGNGSWTDPVFFYVPAKTTYENFMHLIIALPVAILLIVGGLVIMLYVFH
RKRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMNRELGQGSFGMVYEGVAK
GVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIM
ELMTRGDLKSYLRSLRPEVEQNNLVLIPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAA
RNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSF
GVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPS
FLEIIGSIKDEMEPSFQEVSFYYSDENKPPEPEELEMELEMEPENMESVPLDPSASSASL
PLPERHSGHKAENGPGPGVLVLRASFDERQPYAHMNGGRANERALPLPQSSTC
NT seq
4122 nt
NT seq
+upstream
nt +downstream
nt
atgaagtctggctccggaggagggtccccgacctcgctgtgggggctcgtgtttctctcc
gccgcgctctcgctctggccgacgagtggagaaatctgtgggcccggcattgacatccgc
aatgactatcagcagctgaagcgcctggaaaactgcacggtgatcgagggcttcctccac
atcctgctcatctccaaggccgaggactaccgaagctaccgcttccccaagctcacggtc
atcaccgagtatttgctgctgtttcgagtggccggccttgagagcctgggagacctcttc
ccgaacctcacagtcatccgtggctggaaactcttctacaactacgcactggtcatcttt
gagatgaccaatctcaaggatattgggctttataatctgaggaacattactcggggggcc
atcaggattgagaaaaacgctgacctctgttacctctccaccatagactggtctctcatc
ttggatgcagtgtccaataactacattgtggggaacaagcccccaaaggaatgtggggac
ctgtgtccagggacattggaggagaagcccatgtgtgagaagaccaccatcaacaatgag
tacaactaccgctgctggaccacaaatcgctgccagaaaatgtgcccaagtgtgtgcggg
aagcgagcctgcacggagaacaacgagtgctgccacccggagtgcctgggcagctgccat
acacctgacgacaacacaacctgtgtggcctgccgacactactactacaaaggcgtgtgc
gtgcctgcctgcccgcctggcacctacaggttcgagggctggcgctgtgtggaccgagat
ttctgcgccaacatccccaacgccgaaagcagtgactcggatggcttcgtcatccacgac
ggcgagtgcatgcaggagtgtccctcaggcttcatccgcaacagcactcagagcatgtac
tgtattccctgcgaaggcccctgccccaaagtttgcggtgatgaagaaaagaaaacaaaa
accatcgattcggttacttctgctcaaatgctccaaggatgcaccatcttgaagggcaat
ctgctgattaacatcaggcgaggcaataacattgcctcggaattggagaacttcatgggg
ctcatcgaggtagtgaccggctacgttaagatccgccattcccatgccttggtctccttg
tctttcctgaagaatcttcgtctcatcttaggagaggaacagctagaagggaactactcc
ttctatgtcctggacaaccagaacttgcagcagctgtgggactggaaccaccggaacctg
accgtcaggtcagggaaaatgtattttgctttcaaccccaagctgtgtgtctctgaaatt
taccgcatggaggaagtgaccggaacaaagggacgtcagagcaaaggggacatcaacacc
aggaacaacggagagcgagcttcctgtgaaagtgatgttctccgtttcacctccaccacc
acctggaagaaccgcatcatcataacatggcaccggtaccggccaccagactaccgggat
ctcatcagtttcacagtttactacaaggaggcaccctttaaaaatgtcacggaatatgac
gggcaggatgcctgtggctccaacagctggaacatggtggatgtggacctacctccgaac
aaggagggggagcctggcattttactgcatgggctgaagccctggacccagtatgctgtc
tatgtcaaggctgtgaccctcaccatggtggaaaacgaccacatccgtggggccaaaagt
gaaatcttgtacattcgcaccaatgcttcagttccttccattcccctagatgtcctctca
gcatccaactcttcctctcagctgattgtgaagtggaatcccccaacgctgcccaatggt
aacttgagttactacattgtgaggtggcagcggcagccgcaggatggctacctgtaccgg
cacaactactgctccaaagacaagatacccatcagaaagtatgccgacggtaccatcgat
gtggaggaggtgacagaaaatcccaagacagaagtgtgtggtggtgataaagggccatgc
tgtgcttgtcctaaaactgaagctgagaagcaggctgagaaggaggaggctgagtaccgt
aaagtctttgagaatttcctccacaattccatctttgtgcccagacccgaaaggaggcgg
agagacgtcatgcaagtggccaacaccaccatgtccagccgaagcaggaacaccacagta
gctgacacctacaatatcacagatccagaagagttcgagacagaatatcctttctttgag
agcagagtggataacaaggagaggactgtcatctccaacctccggccattcactctctac
cgtatcgatatccacagctgcaaccacgaggctgagaagctgggctgcagcgcttccaac
tttgtctttgctagaaccatgccagcagaaggagcagatgacattcctggcccagtgacc
tgggagccaagacctgaaaactccatctttttaaagtggccagaaccagagaaccccaac
ggattgattctaatgtatgaaataaaatacgggtcccaagtcgaggatcagcgggaatgt
gtatccagacaggagtacaggaagtatggaggggccaaacttaaccgtctaaacccaggg
aactatacagcccggattcaggctacttccctctctgggaatgggtcgtggacagatcct
gtgttcttctatgtcccagccaaaacgacgtatgagaatttcatgcatctgatcattgct
ctgccagttgccattctgctgatcgttggggggctggtaatcatgctgtatgtcttccat
agaaagagaaataacagcaggttgggcaatggagtgttgtacgcctccgtgaaccctgag
tatttcagcgcagctgatgtgtacgtgcctgatgaatgggaggtagctcgagagaagatc
accatgaaccgggagcttggacaagggtcctttgggatggtctatgaaggagtggccaag
ggtgtggtcaaggatgaacctgaaaccagagtggccatcaagacagtgaacgaggctgca
agtatgcgtgaaagaatcgagtttctcaacgaggcttcagtgatgaaggagttcaactgt
caccatgtggtccggttgctaggtgtggtgtctcaaggccagcccaccctggtcatcatg
gaactaatgacacgaggtgatctcaaaagttatctccggtctctaaggccagaagtggag
cagaataatctagtcctcattcctccgagcttaagcaaaatgatccagatggctggagag
attgcagacggtatggcctacctcaacgccaacaagttcgtccacagagaccttgctgcg
cggaactgcatggtagctgaagatttcacggtcaaaattggagattttggtatgacacga
gacatctatgagacagactactaccggaaaggcgggaaggggttgctgcctgtgcgctgg
atgtctcccgagtccctcaaggatggtgtcttcactactcattctgacgtctggtccttt
ggggtcgtcctctgggagattgccacactggctgagcagccctaccagggcttgtccaac
gagcaagttcttcgtttcgtcatggagggcggccttctagacaagccagacaactgcccc
gatatgctgtttgaacttatgcgcatgtgctggcagtataaccccaagatgcggccctcc
ttcttggagatcatcggcagcatcaaggatgagatggagcccagcttccaggaggtctcc
ttctactacagtgacgagaacaagcctcccgagccggaggagctggagatggagctggag
atggagcccgagaacatggagagcgtcccgctggacccttcggcctcctcagcctccctg
cctctgcctgaaagacactcaggacacaaggctgaaaatggcccaggccccggcgtgctg
gttctccgtgccagttttgatgagagacagccttacgctcacatgaacgggggccgcgcc
aacgagagggccttgcctctgccccagtcctcgacctgctga
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