Arvicanthis niloticus (African grass rat): 117717807
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Entry
117717807 CDS
T08817
Symbol
Gart
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
anu
Arvicanthis niloticus (African grass rat)
Pathway
anu00230
Purine metabolism
anu00670
One carbon pool by folate
anu01100
Metabolic pathways
anu01523
Antifolate resistance
Module
anu_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
anu00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
117717807 (Gart)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
117717807 (Gart)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
117717807 (Gart)
Enzymes [BR:
anu01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
117717807 (Gart)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
117717807 (Gart)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
117717807 (Gart)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
GARS_N
AIRS_C
GARS_C
AIRS
ATP-grasp
ATP-grasp_3
CPSase_L_D2
ATP-grasp_2
Dala_Dala_lig_C
ATP-grasp_4
RimK
ATP-grasp_5
Sacchrp_dh_NADP
LUD_dom
Motif
Other DBs
NCBI-GeneID:
117717807
NCBI-ProteinID:
XP_034371097
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All DBs
Position
12:complement(72975463..73003622)
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AA seq
1013 aa
AA seq
DB search
MAARVLVIGSGGREHTLAWKLAQSPHVKQVLVAPGNAGTACSGKISNAAVSVSDHTALAQ
FCKGEKIELVVVGPEAPLAAGIVGDLTSAGVRCFGPTAQAAQLESSKKFAKEFMDRHGIP
TAQWRAFTNPEDACSFITSANFPALVVKASGLAAGKGVIVAKSKAEACKAVQEIMQEKSF
GAAGETVVVEEFLEGEEVSCLCFTDGKTIAPMPPAQDHKRLRDGDQGPNTGGMGAYCPAP
QVSKDSLVKIKNTILQRTVDGMQQEGAPYTGILYAGIMLTKDGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIQATLDGLLSASLPVWLENHSAVTVVMASEGYPGAYTKGVEITGFAEA
QALGLQVFHAGTALKDGKVVTSGGRVLTVTAVQENLMSALDEARKGLAALKFEGAIYRKD
IGFRAVAFLQRPRGLTYKDSGVDIAAGNMLVKKIQPLAKATSRPGCSVDLGGFAGLFDLK
AAGFKDPLLASGTDGVGTKLKIAQLCNKHDSIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDLSTTEAVVAGIAAACRQAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERHQKLP
QLERITEGDAVVGVASSGLHSNGFSLVRKIVERSSLQYSSPAPGGCGDQTLGDLLLTPTR
IYSYSLLPIIRSGRVKAFAHITGGGLLENIPRVLPQKFGVDLDACTWRVPKIYSWLQQEG
QLSEEEMARTFNCGVGAALVVSRDQTEQVLQDIRQHQEEAWVIGSVVACPEGSPRVRVKN
LIETIQTNGSLVANGFPRSNFPVQQKKARVAVLISGTGSNLQALIDSTADSKSSSHIVLV
ISNKAAVAGLDRAERAGIPTRVINHKLYKNRVEFDNAVDCVLEEFSIDIVCLAGFMRILS
GPFVRKWDGKMLNIHPSLLPSFKGSNAHEQVLEAGVTITGCTVHFVAEDVDAGQIILQEA
VPVQRGDTVATLSERVKVAEHKIFPAALQLVASGAVQLGEDGKIHWTEERGSS
NT seq
3042 nt
NT seq
+upstream
nt +downstream
nt
atggcagcccgagttcttgtaattggtagtggaggaagagaacataccctggcctggaaa
ctcgcacagtcccctcatgtcaaacaagtgttggttgccccaggaaacgcaggcaccgct
tgctctgggaagatctccaatgctgctgtctccgtcagtgatcacactgctcttgcccag
ttctgcaaaggtgaaaagattgaacttgtagttgttggaccagaggcccctctggctgca
ggaattgttggggacctgacctctgcaggagtgcgatgctttggccccacagcacaagca
gctcaattagaatccagtaaaaagtttgccaaagagttcatggaccgacatggaatccca
actgcacagtggagagccttcaccaaccctgaagatgcctgcagctttatcacgagcgcg
aactttcccgctttggttgtgaaggccagtggccttgcagcaggaaagggggtgattgtg
gcaaagagcaaagcagaagcctgcaaagctgtccaggagatcatgcaggaaaagtctttt
ggagcagctggtgaaacagttgttgtggaagagtttctggaaggagaggaagtgtcttgc
ctgtgcttcactgacgggaagacaatagccccaatgcccccagcacaagaccataagcga
ttgcgggatggagaccagggccccaacacagggggaatgggagcctactgcccagcacct
caggtttctaaagattcgttagtaaaaattaaaaacactattcttcagagaacagtagac
ggcatgcagcaggagggggcgccgtacacaggaattctttatgctggcataatgctgacc
aaagatggcccaaaagttttggagtttaattgccgttttggtgatccagaatgccaggtc
atcctcccacttcttaaaagcgacctttatgaagtcattcaggccaccttagatggcctg
ctgagcgcgtctctgcctgtgtggctagaaaaccacagtgccgtaactgttgtcatggcg
agtgaagggtaccctggagcctacaccaaaggcgtggagataacagggtttgctgaggcc
caggccttaggactgcaggtcttccatgcaggcactgctcttaaagatggcaaagtggtg
accagtgggggcagagtcctcaccgtgacagctgtccaagaaaatctcatgtcagccctt
gacgaggccaggaaaggactcgccgctctaaagtttgagggagccatttatagaaaggac
attggcttccgtgctgtggccttcctccagcggcccaggggcctgacttacaaggactcc
ggagtagacattgcagccggaaatatgctggttaagaaaattcagcctttagcaaaagcc
acctccagaccaggctgcagtgttgaccttgggggctttgctggtctttttgatttgaaa
gcagctggtttcaaagatcctcttctggcctctggaacagatggtgttggaactaaactg
aagattgcccagctgtgtaataagcacgattctatcggtcaagacttggttgcgatgtgt
gtgaacgacatcctcgcccaaggagcagagcccctcttcttcctggattacttttcctgt
ggaaaactcgacctcagtacaactgaagctgttgttgctggaatcgctgcagcctgtcga
caggcgggctgtgctctcctaggtggggagacagcagagatgcccgacatgtaccctcct
ggagagtatgatcttgctgggtttgccgttggtgctatggagagacaccagaagctccct
cagctagaaaggatcacagaaggggatgctgttgttggagtagcttcgtctggtcttcac
agcaatgggtttagccttgtgaggaaaatcgtggagaggtcttccctccagtactcctcc
ccagcacctggtggctgtggagatcagaccttgggggacttacttctaactccaaccagg
atctacagctactcactgctgcctatcatacgttcaggacgtgtcaaagcttttgctcat
atcactggaggcggattgctggaaaacatccccagagtcctccctcagaagtttggagta
gacttagatgcctgcacctggagggtccccaagatctactcatggctacagcaggaagga
cagctctctgaagaagaaatggctcggacatttaactgtggggttggagctgccctggtg
gtgtcgagggaccagacagagcaggttctacaagacattcggcagcaccaggaagaagcc
tgggtgataggcagtgtcgttgcgtgtcctgaaggctcccctcgtgtcagagttaagaat
ctgattgaaaccatacaaacaaatgggtcactggtggcaaatggcttcccgagaagtaat
tttcctgtccaacaaaagaaggcaagagtggctgtcctaatatctggaacagggtcaaac
ctccaggcgctcatagacagcactgcagattccaagagctcctctcacattgttctcgtc
atctccaacaaagctgctgtagctggcttagaccgagcagagcgagccggtattcccacc
agggtaattaatcataaattatataaaaatcgtgttgaatttgacaacgcagttgactgt
gtcctggaagagttttccatagacatcgtctgtctcgcaggattcatgaggattctctct
ggcccttttgtcagaaaatgggatgggaaaatgctcaacatccacccatccttgctccct
tcttttaagggttcaaatgctcacgagcaagtcctagaagctggagtcacaattactggg
tgtaccgtacactttgtggctgaagatgtagatgccggacaaatcatcctgcaggaagct
gtccctgtgcagaggggtgacactgttgctacactgtctgaacgagtcaaagtagcagaa
cataagatctttcctgcagccctccagctggtggccagcggggccgtgcagctgggagaa
gatggcaagatccactggaccgaagagcggggctcgtcctga
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