KEGG   Arvicanthis niloticus (African grass rat): 143436721
Entry
143436721         CDS       T08817                                 
Symbol
Akt1
Name
(RefSeq) RAC-alpha serine/threonine-protein kinase
  KO
K04456  RAC serine/threonine-protein kinase [EC:2.7.11.1]
Organism
anu  Arvicanthis niloticus (African grass rat)
Pathway
anu01521  EGFR tyrosine kinase inhibitor resistance
anu01522  Endocrine resistance
anu01524  Platinum drug resistance
anu04010  MAPK signaling pathway
anu04012  ErbB signaling pathway
anu04014  Ras signaling pathway
anu04015  Rap1 signaling pathway
anu04022  cGMP-PKG signaling pathway
anu04024  cAMP signaling pathway
anu04062  Chemokine signaling pathway
anu04066  HIF-1 signaling pathway
anu04068  FoxO signaling pathway
anu04071  Sphingolipid signaling pathway
anu04072  Phospholipase D signaling pathway
anu04140  Autophagy - animal
anu04150  mTOR signaling pathway
anu04151  PI3K-Akt signaling pathway
anu04152  AMPK signaling pathway
anu04210  Apoptosis
anu04211  Longevity regulating pathway
anu04213  Longevity regulating pathway - multiple species
anu04218  Cellular senescence
anu04261  Adrenergic signaling in cardiomyocytes
anu04370  VEGF signaling pathway
anu04371  Apelin signaling pathway
anu04380  Osteoclast differentiation
anu04510  Focal adhesion
anu04517  IgSF CAM signaling
anu04518  Integrin signaling
anu04550  Signaling pathways regulating pluripotency of stem cells
anu04611  Platelet activation
anu04613  Neutrophil extracellular trap formation
anu04620  Toll-like receptor signaling pathway
anu04625  C-type lectin receptor signaling pathway
anu04630  JAK-STAT signaling pathway
anu04660  T cell receptor signaling pathway
anu04662  B cell receptor signaling pathway
anu04664  Fc epsilon RI signaling pathway
anu04666  Fc gamma R-mediated phagocytosis
anu04668  TNF signaling pathway
anu04722  Neurotrophin signaling pathway
anu04725  Cholinergic synapse
anu04728  Dopaminergic synapse
anu04810  Regulation of actin cytoskeleton
anu04910  Insulin signaling pathway
anu04914  Progesterone-mediated oocyte maturation
anu04915  Estrogen signaling pathway
anu04917  Prolactin signaling pathway
anu04919  Thyroid hormone signaling pathway
anu04920  Adipocytokine signaling pathway
anu04922  Glucagon signaling pathway
anu04923  Regulation of lipolysis in adipocytes
anu04926  Relaxin signaling pathway
anu04929  GnRH secretion
anu04931  Insulin resistance
anu04932  Non-alcoholic fatty liver disease
anu04933  AGE-RAGE signaling pathway in diabetic complications
anu04935  Growth hormone synthesis, secretion and action
anu04936  Alcoholic liver disease
anu04973  Carbohydrate digestion and absorption
anu05010  Alzheimer disease
anu05017  Spinocerebellar ataxia
anu05132  Salmonella infection
anu05135  Yersinia infection
anu05142  Chagas disease
anu05145  Toxoplasmosis
anu05152  Tuberculosis
anu05160  Hepatitis C
anu05161  Hepatitis B
anu05162  Measles
anu05163  Human cytomegalovirus infection
anu05164  Influenza A
anu05165  Human papillomavirus infection
anu05166  Human T-cell leukemia virus 1 infection
anu05167  Kaposi sarcoma-associated herpesvirus infection
anu05168  Herpes simplex virus 1 infection
anu05169  Epstein-Barr virus infection
anu05170  Human immunodeficiency virus 1 infection
anu05200  Pathways in cancer
anu05205  Proteoglycans in cancer
anu05207  Chemical carcinogenesis - receptor activation
anu05208  Chemical carcinogenesis - reactive oxygen species
anu05210  Colorectal cancer
anu05211  Renal cell carcinoma
anu05212  Pancreatic cancer
anu05213  Endometrial cancer
anu05214  Glioma
anu05215  Prostate cancer
anu05218  Melanoma
anu05220  Chronic myeloid leukemia
anu05221  Acute myeloid leukemia
anu05222  Small cell lung cancer
anu05223  Non-small cell lung cancer
anu05224  Breast cancer
anu05225  Hepatocellular carcinoma
anu05226  Gastric cancer
anu05230  Central carbon metabolism in cancer
anu05231  Choline metabolism in cancer
anu05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
anu05415  Diabetic cardiomyopathy
anu05417  Lipid and atherosclerosis
anu05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:anu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    143436721 (Akt1)
   04012 ErbB signaling pathway
    143436721 (Akt1)
   04014 Ras signaling pathway
    143436721 (Akt1)
   04015 Rap1 signaling pathway
    143436721 (Akt1)
   04370 VEGF signaling pathway
    143436721 (Akt1)
   04371 Apelin signaling pathway
    143436721 (Akt1)
   04630 JAK-STAT signaling pathway
    143436721 (Akt1)
   04668 TNF signaling pathway
    143436721 (Akt1)
   04066 HIF-1 signaling pathway
    143436721 (Akt1)
   04068 FoxO signaling pathway
    143436721 (Akt1)
   04072 Phospholipase D signaling pathway
    143436721 (Akt1)
   04071 Sphingolipid signaling pathway
    143436721 (Akt1)
   04024 cAMP signaling pathway
    143436721 (Akt1)
   04022 cGMP-PKG signaling pathway
    143436721 (Akt1)
   04151 PI3K-Akt signaling pathway
    143436721 (Akt1)
   04152 AMPK signaling pathway
    143436721 (Akt1)
   04150 mTOR signaling pathway
    143436721 (Akt1)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    143436721 (Akt1)
   04518 Integrin signaling
    143436721 (Akt1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    143436721 (Akt1)
  09143 Cell growth and death
   04210 Apoptosis
    143436721 (Akt1)
   04218 Cellular senescence
    143436721 (Akt1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    143436721 (Akt1)
   04550 Signaling pathways regulating pluripotency of stem cells
    143436721 (Akt1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    143436721 (Akt1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    143436721 (Akt1)
   04613 Neutrophil extracellular trap formation
    143436721 (Akt1)
   04620 Toll-like receptor signaling pathway
    143436721 (Akt1)
   04625 C-type lectin receptor signaling pathway
    143436721 (Akt1)
   04660 T cell receptor signaling pathway
    143436721 (Akt1)
   04662 B cell receptor signaling pathway
    143436721 (Akt1)
   04664 Fc epsilon RI signaling pathway
    143436721 (Akt1)
   04666 Fc gamma R-mediated phagocytosis
    143436721 (Akt1)
   04062 Chemokine signaling pathway
    143436721 (Akt1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    143436721 (Akt1)
   04922 Glucagon signaling pathway
    143436721 (Akt1)
   04923 Regulation of lipolysis in adipocytes
    143436721 (Akt1)
   04920 Adipocytokine signaling pathway
    143436721 (Akt1)
   04929 GnRH secretion
    143436721 (Akt1)
   04915 Estrogen signaling pathway
    143436721 (Akt1)
   04914 Progesterone-mediated oocyte maturation
    143436721 (Akt1)
   04917 Prolactin signaling pathway
    143436721 (Akt1)
   04926 Relaxin signaling pathway
    143436721 (Akt1)
   04935 Growth hormone synthesis, secretion and action
    143436721 (Akt1)
   04919 Thyroid hormone signaling pathway
    143436721 (Akt1)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    143436721 (Akt1)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    143436721 (Akt1)
  09156 Nervous system
   04725 Cholinergic synapse
    143436721 (Akt1)
   04728 Dopaminergic synapse
    143436721 (Akt1)
   04722 Neurotrophin signaling pathway
    143436721 (Akt1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    143436721 (Akt1)
  09149 Aging
   04211 Longevity regulating pathway
    143436721 (Akt1)
   04213 Longevity regulating pathway - multiple species
    143436721 (Akt1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    143436721 (Akt1)
   05205 Proteoglycans in cancer
    143436721 (Akt1)
   05207 Chemical carcinogenesis - receptor activation
    143436721 (Akt1)
   05208 Chemical carcinogenesis - reactive oxygen species
    143436721 (Akt1)
   05230 Central carbon metabolism in cancer
    143436721 (Akt1)
   05231 Choline metabolism in cancer
    143436721 (Akt1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    143436721 (Akt1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    143436721 (Akt1)
   05212 Pancreatic cancer
    143436721 (Akt1)
   05225 Hepatocellular carcinoma
    143436721 (Akt1)
   05226 Gastric cancer
    143436721 (Akt1)
   05214 Glioma
    143436721 (Akt1)
   05221 Acute myeloid leukemia
    143436721 (Akt1)
   05220 Chronic myeloid leukemia
    143436721 (Akt1)
   05218 Melanoma
    143436721 (Akt1)
   05211 Renal cell carcinoma
    143436721 (Akt1)
   05215 Prostate cancer
    143436721 (Akt1)
   05213 Endometrial cancer
    143436721 (Akt1)
   05224 Breast cancer
    143436721 (Akt1)
   05222 Small cell lung cancer
    143436721 (Akt1)
   05223 Non-small cell lung cancer
    143436721 (Akt1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    143436721 (Akt1)
   05170 Human immunodeficiency virus 1 infection
    143436721 (Akt1)
   05161 Hepatitis B
    143436721 (Akt1)
   05160 Hepatitis C
    143436721 (Akt1)
   05164 Influenza A
    143436721 (Akt1)
   05162 Measles
    143436721 (Akt1)
   05168 Herpes simplex virus 1 infection
    143436721 (Akt1)
   05163 Human cytomegalovirus infection
    143436721 (Akt1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    143436721 (Akt1)
   05169 Epstein-Barr virus infection
    143436721 (Akt1)
   05165 Human papillomavirus infection
    143436721 (Akt1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    143436721 (Akt1)
   05135 Yersinia infection
    143436721 (Akt1)
   05152 Tuberculosis
    143436721 (Akt1)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    143436721 (Akt1)
   05142 Chagas disease
    143436721 (Akt1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    143436721 (Akt1)
   05017 Spinocerebellar ataxia
    143436721 (Akt1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    143436721 (Akt1)
   05418 Fluid shear stress and atherosclerosis
    143436721 (Akt1)
   05415 Diabetic cardiomyopathy
    143436721 (Akt1)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    143436721 (Akt1)
   04932 Non-alcoholic fatty liver disease
    143436721 (Akt1)
   04931 Insulin resistance
    143436721 (Akt1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    143436721 (Akt1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    143436721 (Akt1)
   01524 Platinum drug resistance
    143436721 (Akt1)
   01522 Endocrine resistance
    143436721 (Akt1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:anu01001]
    143436721 (Akt1)
Enzymes [BR:anu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     143436721 (Akt1)
Protein kinases [BR:anu01001]
 Serine/threonine kinases: AGC group
  AKT/PKB family
   143436721 (Akt1)
SSDB
Other DBs
NCBI-GeneID: 143436721
NCBI-ProteinID: XP_076777117
LinkDB
Position
23:6211085..6232213
AA seq 480 aa
MNDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVEQRESPLNNFSVAQC
QLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKRQEEETMDF
RSGSPSDNSGAEEMEVSLTKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKI
LKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLS
RERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGI
KDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFEL
ILMEEIRFPRTLGPEAKSLLSGLLKKDPTQRLGGGSEDAKEIMQHRFFANIVWQDVYEKK
LSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDSMECVDSERRPHFPQFSYSASGTA
NT seq 1443 nt   +upstreamnt  +downstreamnt
atgaacgacgtagccattgtgaaggagggctggctgcacaaacgaggggaatatattaaa
acctggcggccacgctacttcctcctcaagaatgatggcacctttattggctacaaggaa
cggcctcaggatgtggagcagagagagtccccactcaacaacttctcagtggcacaatgc
cagctgatgaagacagagcggccaaggcccaacaccttcatcatccgctgcctgcagtgg
accacagtcattgagcgcaccttccatgtggagacgcctgaggagcgggaagagtggacc
actgccattcagactgtggcggatggactcaaaaggcaggaggaggagacgatggacttc
cggtcaggctcacccagtgacaactcgggagctgaagagatggaggtgtccctgaccaag
cccaagcaccgtgtgaccatgaatgagtttgagtacctgaagctgctgggcaagggcacc
tttgggaaggtgatcctggtgaaggagaaggccacgggccgctactacgccatgaagatc
ctcaagaaggaggtcatcgttgccaaggatgaggtcgcccacacgcttactgagaaccgt
gtcctgcagaactctaggcatcccttccttacggccctcaagtactcattccagacccac
gaccgtctctgctttgtcatggagtatgccaatgggggcgagctcttcttccacctgtct
cgtgagcgtgtgttctcggaggaccgggcccgcttctatggtgcggagattgtgtccgcc
ctggactacttgcactccgagaagaatgtggtgtaccgggacctgaagctggagaacctc
atgctggacaaagacgggcacatcaagataacggacttcgggctgtgcaaggagggtatc
aaggatggtgccactatgaagacattctgtggaacacccgagtacctggcccctgaggtg
ctggaggacaacgactatggccgtgccgtggactggtgggggctgggcgtggtcatgtac
gagatgatgtgtggccgcctgcccttctacaaccaggaccacgagaagctgttcgagctc
atcctcatggaggagatccgcttcccacgcacactcggcccagaggctaagtccctgctc
tccgggctgctcaagaaggaccctacacagaggctcggtgggggctctgaggacgccaag
gagatcatgcagcaccgattctttgccaacatcgtgtggcaagatgtgtatgagaagaag
ctgagcccacccttcaagccccaggtcacctctgagacggacaccaggtatttcgatgag
gagttcacagctcagatgatcaccatcacgccgcctgatcaagatgacagcatggagtgc
gtggacagcgagcggaggccgcacttcccccagttctcctactcagccagtggcacagcc
tga

DBGET integrated database retrieval system