Arvicanthis niloticus (African grass rat): 143440403
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Entry
143440403 CDS
T08817
Symbol
Pde8b
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X1
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
anu
Arvicanthis niloticus (African grass rat)
Pathway
anu00230
Purine metabolism
anu01100
Metabolic pathways
anu04927
Cortisol synthesis and secretion
anu04934
Cushing syndrome
anu05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
anu00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
143440403 (Pde8b)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
143440403 (Pde8b)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
143440403 (Pde8b)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
143440403 (Pde8b)
Enzymes [BR:
anu01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
143440403 (Pde8b)
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Paralog
GFIT
Motif
Pfam:
PDEase_I
PDE8A_N
PDE8
PAS_9
PAS
PAS_3
PDE8_3rd
PAS_4
PAS_8
Motif
Other DBs
NCBI-GeneID:
143440403
NCBI-ProteinID:
XP_076783290
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Position
29:complement(19245983..19470956)
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AA seq
893 aa
AA seq
DB search
MGCAPSIHVSQSGVIYCRDSDESNSPRQTSSVSQGPTAPLHGLFVQTDAADAMPPSRAAG
PPGAVRVRRSRAELGSGSSTGSSGPATTTCRGRRRHCCSSAEAETQTSYTSVKQVSSAEV
RIGPMRLTQDPIQVLLIFAKEDSQSDGFWWACDRAGYRCNIARTPESALECFLDKHHEII
VIDHRQSRNFDAEAVCRSIRATNPSEHTVILAVVSQASDDHEEASVLPLLHAGFNRRFME
NSSIIACYNELIQIEHGEVRSQFKLRACNSVFTALDHCHEAIEITSDDHVIQYVNPAFER
MMGYHKGELLGKELADLPKSDKNRADLLDTINTCIKKGKEWQGVYYARRKSGDSIQQHVK
ITPVIGQGGKIRHFVSLKKLCCTADNSKQIHRIHRDSGDNSQTEPHSFRHKSRRKESIDV
KSISSRGSDAPSLQNRRYPSMARIHSMTIEAPITKVINIINAAQENSPVTVAEALDRVLE
ILRTTELYSPQLGTKDEDPHTSDLVGGLMTDGLKRLSGNEYVFTKNVHHSHSHLSMPITI
NDVPPSIAQLLDNEESWDFNIFELEAVTHKRPLVYLGLKVFSRFGVCEFLNCTETTLRAW
LQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVHDVDHP
GRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDTKCNIFKNIDRNHYRTLRQAI
IDMVLATEMTKHFEHVNKFVNSINKPLAAEPWSDRLFQSEGSDCECNPTGKNFPENQILI
KRMMIKCADVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIPKS
QISFIDYFITDMFDAWDAFAHLPALMQHLADNYKHWKTLDDLKCKSLRLPSDS
NT seq
2682 nt
NT seq
+upstream
nt +downstream
nt
atgggctgcgcccccagcatccatgtctcgcagagcggtgtgatctactgccgggactcg
gatgagtccaactcgccccgccagaccagcagcgtgtcgcagggccccacggcgcccctg
cacggcctcttcgtgcagaccgacgccgccgacgccatgcccccgagccgcgcggcggga
cccccgggcgctgtccgagtccgcaggtcccgggctgagctgggcagtggcagcagcacg
gggtcctcggggcccgccacgaccacctgccggggccggaggcgtcactgctgcagcagt
gccgaggccgagactcagactagctacaccagtgtcaagcaggtatcttctgcggaggtg
cgcatcgggcccatgagactgacacaggaccctatccaggttctgctaatctttgcaaag
gaagatagccaaagtgacggcttctggtgggcctgtgacagagctggctacagatgtaac
attgctcgcactccggagtcagccctcgaatgctttctggacaagcatcatgaaattatt
gtgatcgatcacaggcaaagccggaactttgatgcagaggccgtgtgcaggtcaatccgg
gccacgaacccctctgagcacacggtgatcctggctgtggtttcacaagcatctgatgac
catgaagaggcctccgtccttcctcttctccatgcaggcttcaaccggagatttatggag
aacagcagcataattgcctgctataatgaactgattcaaatagaacacggggaagttcgc
tcacagttcaaattacgggcctgtaattcagtgtttactgcgttagaccactgtcacgaa
gccatagaaataacaagtgatgaccatgtgattcagtatgtcaaccctgcctttgagagg
atgatgggctaccacaaaggggagctcctggggaaggaactcgctgacctacctaagagt
gacaagaaccgggcagacctcctggacaccatcaacacgtgcatcaagaagggaaaggag
tggcaaggggtttactatgccagacggaaatccggggacagcatccaacagcacgtgaag
atcaccccagtgattggccaaggagggaaaattagacactttgtctccctcaagaagctg
tgttgtaccgctgacaatagcaagcagattcacaggattcatcgtgattccggggacaac
tctcagacagagcctcattcgttcagacacaagagcaggaggaaagagtccattgatgtg
aaatcaatatcttctcggggcagtgatgcaccaagcctacagaatcgccgctatccctcc
atggcaaggattcactccatgaccattgaggctccaatcacaaaggttataaatataatc
aacgcagctcaagaaaacagcccagttacagtagcagaagccttggacagagttctagaa
attttacggaccacagaactctactcccctcagctgggaaccaaagatgaagatccccac
accagcgatcttgttggaggcctgatgactgatggcttgaagagactgtcagggaacgag
tatgtgtttacaaagaatgttcaccacagtcacagtcacctctcgatgcccatcaccatc
aacgatgtccccccaagtatcgcccagctccttgacaatgaggaaagttgggacttcaac
atctttgaattggaagctgttacacataaaaggccacttgtgtacctgggcttaaaggtc
ttctctcggtttggagtatgtgaatttttaaactgtactgaaaccactcttcgggcctgg
ctgcaagtgattgaagccaactaccactcctccaacgcctaccacaactccacccacgct
gcagacgtactgcatgccacagcgtttttccttggaaaggaaagagtaaagggaagcctg
gaccagctagatgaggtagctgctctgattgctgccacagtccatgacgtggatcaccct
ggaagaaccaactctttcctgtgcaacgcgggcagcgaactcgccgtgctctacaatgac
actgcggtcttggagagtcaccacacagccctggccttccagctcaccgtcaaggacacc
aagtgcaacatcttcaagaatattgacaggaaccactatcgaacgctgcgccaggctatt
atcgacatggttttggccacggagatgacaaaacactttgaacatgtgaacaaatttgtg
aacagcatcaacaagccactggcggctgagccctggtctgatcgtctcttccagagtgaa
ggcagcgattgtgaatgcaaccctactgggaagaactttcctgaaaaccaaatcctcatc
aaacgcatgatgatcaagtgtgctgacgtggccaacccgtgccggcccttggacctgtgc
attgaatgggctggaaggatctctgaggagtattttgctcagactgatgaagagaagagg
caggggctgcctgtggtgatgccagtatttgaccgcaatacctgcagcatccccaagtcc
cagatctctttcatcgattacttcataactgacatgtttgacgcttgggatgcctttgct
cacctgcctgccctgatgcagcacctggctgataactataaacactggaagacactggat
gacctcaagtgcaaaagtctgagacttccatctgacagctaa
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