Amycolatopsis nalaikhensis: QP939_29630
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Entry
QP939_29630 CDS
T10497
Name
(GenBank) folylpolyglutamate synthase/dihydrofolate synthase family protein
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
anw Amycolatopsis nalaikhensis
Pathway
anw00790
Folate biosynthesis
anw01100
Metabolic pathways
anw01240
Biosynthesis of cofactors
Module
anw_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
anw00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
QP939_29630
Enzymes [BR:
anw01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
QP939_29630
6.3.2.17 tetrahydrofolate synthase
QP939_29630
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
WIV53080
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Position
6060734..6062389
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AA seq
551 aa
AA seq
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MPQDETGRKPDLSDLDSFAGVDELGTSGYEDSDDHDPELDVRDTAFEAGGGARGGIGGVG
QLGDNLATGPVPDLTVPEDAELHELDDQGEQAEYGDPDGPEARRELLAVEAELNQRWPET
KIEPSLTRISALTQLLGEPNRGYPVLHVAGTNGKGSTARMIDALLTRMGLRVGRYTSPHL
QLVTERIALDGRPISAARYAELWHDIAPYVAMVDGAAADGVAMSKFEILTGMAFAAFADA
PVEAAVLEAGLGGLWDATNVADADVAVLTPIGLDHVEYLGPDAVSAAREKAGIIKPGSVA
VIGEQDSEVLKVLLERAVEVDAAVARAGSEFGVLEREVAVGGQLLKLQGLGGVYDEIFLP
LHGAHQAANAALALAAVEAFFGAGKDKQLVVEAVREAFAEVETPGRLERVRAAPTVLLDA
AHNPHGARALAATVAEEFAFRRLVAVVGVMAEKDAHGILDALEPVVSDIVVTRNSSPRSM
PLEELNQLAISVFGEDRVVAETDLETAIETAIALVETNDDPEEPLSGGGVLVTGSVVTAG
EARTLFGKEPA
NT seq
1656 nt
NT seq
+upstream
nt +downstream
nt
gtgccgcaggatgagacaggtcgcaagccggacctgtcggatctggacagcttcgcgggc
gtcgacgagctgggcacgtcgggctacgaggactccgacgaccacgacccggagctggac
gtccgcgacaccgcgttcgaggcgggcggcggcgcgcgcggcgggatcggcggcgtcggc
cagctgggcgacaacctcgccaccggcccggtgcccgacctgaccgtgcccgaggacgcc
gagctccacgagctcgacgaccagggcgagcaggcggagtacggcgacccggacggcccc
gaagcgcggcgcgagctgctggccgtcgaggccgagctgaaccagcgctggccggagacg
aagatcgagccgtcgctcacccggatctcggcgctgacgcagctgctgggcgagccgaac
cgcggctacccggtgctgcacgtggccggcacgaacggcaagggctccacggcccggatg
atcgacgcgctgctgacccggatgggcctgcgcgtcggccgctacaccagcccgcacctg
cagctggtcaccgagcggatcgcgctcgacggccgcccgatctccgccgcgcgctacgcc
gagctgtggcacgacatcgcgccgtacgtggcgatggtggacggcgcggccgcggacggc
gtcgcgatgagcaagttcgaaatcctcaccggcatggccttcgccgcgttcgccgacgcg
ccggtcgaggccgccgtgctggaggcgggcctcggcgggctctgggacgccacgaacgtc
gccgacgccgacgtcgcggtcctcaccccgatcggcctcgaccatgtcgagtacctgggg
ccggacgcggtgagcgcggcccgggaaaaggccgggatcatcaagcccggctcggtcgcg
gtcatcggcgagcaggactccgaagtgctgaaggtgctgctggaacgcgcggtcgaggtc
gacgccgcggtcgcgcgcgcgggcagcgagttcggcgtgctggagcgcgaggtcgccgtc
ggcgggcagctgctgaagctgcagggcctcggcggcgtgtacgacgagatcttcctgccg
ctgcacggcgcccaccaggccgcgaacgccgcgctcgcgctggccgcggtcgaggcgttc
ttcggcgcgggcaaggacaagcagctggtcgtcgaggcggtgcgcgaggcgttcgccgag
gtcgagacgccgggacggctcgagcgcgtccgcgcggcaccgaccgtgctgctcgacgcg
gcccacaacccgcacggcgcccgcgcgctcgcggcgacggtggccgaggagttcgccttc
cgccgcctggtcgcggtggtcggcgtgatggcggagaaggacgcgcacggcatcctcgac
gcgctggagccggtggtgtccgacatcgtcgtgacgcgtaactcgtcgccgcggtcgatg
ccgctggaggagctcaaccagctggcgatctcggtgttcggcgaggaccgcgtggtcgcc
gagacggacctggagacggcgatcgagacggcgatcgcgctcgtggagaccaacgacgac
cccgaagagccgctgtcgggcggtggcgtgctcgtcaccgggtccgtggtcaccgcgggc
gaggcgcgcacgctgttcgggaaggagccggcgtga
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