Amycolatopsis keratiniphila: AORI_1479 Help Entry AORI_1479         CDS       T02678                                  Name (GenBank) amino acid adenylation   KO K16429   nonribosomal peptide synthetase CepB Organism aoi  Amycolatopsis keratiniphila Pathway aoi01055   Biosynthesis of vancomycin group antibiotics Brite KEGG Orthology (KO) [BR:aoi00001]  09100 Metabolism   09109 Metabolism of terpenoids and polyketides    01055 Biosynthesis of vancomycin group antibiotics     AORI_1479  09180 Brite Hierarchies   09181 Protein families: metabolism    01008 Polyketide biosynthesis proteins [BR:aoi01008]     AORI_1479 Polyketide biosynthesis proteins [BR:aoi01008]  Nonribosomal peptide synthetase (NRPS)   Linear NRPS    Vancomycin synthetase     AORI_1479 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Condensation AMP-binding PP-binding AMP-binding_C PapA_C HTH_Tnp_1 Motif Other DBs NCBI-ProteinID:  AGM04067 UniProt:  R4SZ73 LinkDB All DBs Position 1550658..1562810 Genome browser AA seq 4050 aa AA seqDB search MNQSRIEEIWPLSPLQAGLLFHAVYDGEGPDVYVGHWILDLDGPVDAARLRAAWEALLSR HAPLRACFRQRKSGETVQIIAKQVDLPWREIDLSQVEDPAEAVRELAEQDRTTRFDLTRA PLLRLTLIRLGDDAHRLVVTCHHTIMDGWSLPIVLAEMSTLYAADGAPTDLPEVTSYREY LAWLGRQDKERSLAAWTERLAGAEEPTLVVPADPGRAPAEPESVEAGLPENVTRALGELA RAKGLTLNTVVQGAWALVLAQLTGRTDVVFGAAVSARPPDLPGVEGMVGLFLNTVPVRVS LQASTPVAGLLTELQKRQSALIPDQYVGLADIQQAAGPGAVFDTLIVFEKFHHDSGELGS AETFGVRVHQGRVAAHYPLTLVAVPGESMYFKLDYLTDLFDRDTALAIIERFTGVLRLLT DAGEATVADIEVTSPAERALVVDAWGTSSQAAPNRTAPELFDTQVERHRDEPAIVDGDRA LSYGELAERAERLAGHLHGKGVRRGDRVAVVLDRSPELIVTLLAVWKAGAAYVPVDPAYP VERVQFMLTDSGPAAVVCAKTYRDAVLDVGLEPIVLDDPRTRRAVEESARRSTATSGLDL AYVMYTSGSTGTPKGVAVSHGDVAALAGEPGWRVGPGDAVLMHASHAFDISLFELWVPLV SGARVVLAGAGAVDGEALARHVADGVTAAHLTAGAFRVLAEESPESVAGLREVLTGGDAV PLSAVERVRRVCPDVRVRHLYGPTEATLCATWWLLEPGDEPGSVLPIGRPLAGRRVYVLD AFLRPVPAGVPGELYLAGAGVAQGYLDRPALTAERFVADPFAADGRMYRTGDLAYWTDQG ALAFAGRADDQVKIRGYRVEPGEIEVVLGGLPGVAQAVVLPRGEHLIGYVVAEAGQDADP ERLRGQLAETLPEFMVPAVVLVLDALPLTVNGKVDRRALPEPDFASKSAGREPVTDAERV LCGVFAEVLGLDRVGIDDSFFELGGDSISSMQVAARARREGIPLTPRQVFEHRTPERLAV LARETAATPRAEAVTGVGEIPRTPVMLALGDDALRPGFAQVRVVVAPAGLDQDTLASALQ AVLDTHDLLRARVEPDGRLIVPERGAVDAAGLVTRVAAGTAELDEVAERELRTATGTLDP SAGIMARLVWVDAGDAGPGRLAFVAHHLAVDAVSWGILLPDLRTAYDELISGRTPALEAP ATSYRQWALRQVEQAHSERTVAELEDWAALLDGADPAGEEDTGQSYSWSTRLTGTEARNL VTLLPGAFHCGIQDVLLAGLAGAVARVRGTGAGLLVDVEGHGREAADGEDLLRTVGWFTS VHPVRFDLSDVDLAAAGSLLKTAKDQIRAVPGDGSGYGLLRHLNPGTAATLAALPSARIG FNYLGRTVLAPEDTAWEPDGEGPLGGGPDMVLAHAVEVSAEVQDTPSGPRLGLAIDARDA GSGLVQRLGEAWAETLSALAALAGDPGAGGHTPSDFALVGLTRRDVTELETAAPGLTDIW PLSPLQEGMLFERAFDADGVDVYQSQRILGLDGPLDAERLREAWTRVLARHESLRTGFHQ LGSGETVQVVVGEAELPWRVVDLSHLDEAAAAAEIERLLAEDQDRRFDVTQPPLLRLSLI RLGADRHRLVLTSHHVVLDGWSTPLVVGEVSAAYAGGQLPAKAPSFKDYLAWLGRQDADA TRAAWRAELDGADEPSLVDADADKTMVMPGEHAELLSEGTTRALTELARANGVTTSTILQ AAWALVLARLAGRTDVVFGSVVAGRPAEVPDVERMVGMFINTVPVRVRLDGGQPVLELIR ELQGRLAALTEHQYLGLPEIQKAVGTGAVFDTIVMIENYPHTADGLGDDGGVAISSVVTR TGTGYPLTMNVSLGSRLRINVSYRPDRIGAGTAAEVARQVVRVLDQVVARPSLPVGRLGV TSEPARESVVERWNATGDAADTTSVLELFRRQAVASPDAVAVVDGERTLSYTGLDRESDR LAGYLAAVGVRRGDRVGVVMERGADLLVALLAVWKAGAAQVPVNVGYPAERIERMLADAG VSVAVCLEASRKAVPDGVEPVVADLPSLDGTRHEAPRVTVGAHDVAYVMYTSGSTGVPKG VAVPHGSVAALASDPGWSQGPGDHVLLHASHAFDASLVELWVPLVSGARVVVAEPGTVDA ERLREAIARGVTTVHLTAGAFRAVAEEAPDSFRGLREILTGGDAVPLASVERMRRACPGV RFRQLYGPTEITLCATWLVLEPGAETGDTLPIGGPLAGRRAYVLDAFLQPVAPGVTGELY LAGAGLAHGYLGNPVSTSERFVADPFAPGERMYRTGDLARWTEQGQLLFGGRADAQVKIR GYRVEPGEIEAVLTEIPDVAQAIVVAREERPGEKRLIAYVTAEPGQGLESAAVRAQLAAR LPEFMVPSVVLVLDGFPLTINGKIDRAALPAPEFVPAAAGREPRTGTERVLCDLFAEILG LDRVGADDGFFELGGDSILSMRLAARARRENLVFGAKQVFDHKTPAGIAAVAEHGGRTRA EDGEGVGEVPLTPVVRALLERDPLGLTRGGMAQWVIVDVPGDLSVTALAAGLGAVLDTHD LLRSRLVATEGEEPRLVVADRGTVDAATLVERAAAGDIDEIASDAAARLDPLAGVMVRAV LADAGRLVVAAHHLVVDVVSWRTLLPDLQAACEAAVAGLRPSLEAPDVSFRRWSRTLTEE AANRTAELATWTEILDGAPRRLGELDPRRDTVSTAGRRTWTRPAGTLADKATSAFHCGVH EVLLATLAGAVTGWRGGTAVVVDVEGHGRQPLGDMDLSRTLGWFTDVHPLRLDTTGADPA DVVAGGDAAGRLLKQVKENVRAVPDGGLGYGMLRHLNPETAPVLAALPKAEIGFNYLGRF SARADGGGEPWRITGIVGDAADDATPLRHVLEIDAVVADGADGPEFSLTVTWARRLLGDA EAESFADAWLAALTGLAAHVDGGGGGHTPSDFPLTALTQREVARIEAAVPDLLDIWPLSP LQEGLLFHSTGEDGLDVYASMRTLALDGPLDAARFRASWQAMLDRHAALRTSFHQLPSGT AVQTISREATLPWQETDLSRLPEDEALAEFDRLAAAQHAERFDLAKGPMLRLHLVRLGER RHRLIFTSHHIVVDGWSLPLLATGVLAVYEAGGDARALPPSASYRDYLAWIADQDKTAAL EAWRTELAGLDEATQIVPPESILTPLAPERVRFALGDEPSRRLAEFCRRHGVTPNTLFQG IWALHLARLTGRRDVVFGAAVAGRPADIPGVEAAVGLFMNMLPVRARLVGTEPVVDMLKN LQERQFDLLPHQHLGQGEIIKAAGRGAAFDTILVFENYPPPPPRLDGPDALVLSPAGNSD DDGHYPLSLRASVAGGPVRGEVIYRPDVLDRAEAEETVATLLRALEQVLAEPRTPVGRIG LIGPEQRRLVVDEWNRTGRPVTEKTLPVLLREQAERTPDAIAVQDAARGLSYRGLVGEVE SLARLLAEAGVRREARVGVLVERSADLAVTLLGVMFAGGAFVPVDPDYPRDRVEFMLANS APGVLVCTKATRSFVPAEFAGTVLVLEDLPAAGPDAALPEPAPEDAAYVIYTSGSTGVPK GVLVTHSGLVNLGYAHIERMAVTSSSRILQLSAIGFDAMVSELYMSLLAGATLVLPDAAS MPPKVTLGDAIRQAEITHLTVSPSVLASEDDLPDTLRTVLTGGEALPAALVDRWSPGRRV IQAYGPTETTICSTMSAPLSPGHDQVPLGGPIHNVGHYVLDAFLRPVPPGVVGELYITGV GLARGYLGRPGLTAERFVASPFAPGERMYRSGDLFRWTREGQLLFAGRVDAQVKVRGYRV EPAEIEAVLAEHPWVGQVAVSVRRDGPGDKRLVAYVVPSAAAGEGNGTLAAALRELAAER LPEYMMPAAFVSLEKMPLTPNGKLDHRALQAPDFAGTSAKREPRTAAEAALCALFADVLG LDQVAPEDSFFELGGDSITSMQLSARARRQGLELTPWQVFEEKTPERLAPLVQELPAEDA PVAVPEPADGTLLALSPDQMDLLEAGLAGE NT seq 12153 nt NT seq  +upstreamnt  +downstreamnt atgaaccagtcgcggattgaggaaatctggccgctgtcgccattgcaggccggattgctc ttccacgcggtttacgacggcgaagggcctgacgtctacgtcggtcattggatcctggac ctggacgggccggtggacgcggccaggctgcgcgcggcctgggaagcgctgctgtcccgg cacgccccgctgcgcgcttgtttccggcagcgcaaatcgggcgagacggtgcagatcatc gccaagcaggtggaccttccgtggcgggagatcgacctctcgcaggtcgaagatcccgcc gaagccgtgcgtgaactggccgagcaggaccggacgaccagattcgatctgacgcgcgcg cccttgctgcggctcactttgatccgcctcggcgacgacgcgcaccgcctggtggtgacc tgccatcacacgatcatggacggctggtcgctgcccatcgtgctggccgagatgtcgacg ctgtacgcggcggacggcgctccgacggacctgccggaagtgacgtcgtaccgggagtac ctggcctggctgggccgtcaggacaaggagcggtcgctcgcggcgtggacggaacggctg gcgggcgccgaggagccgacgctggtggtgcctgcggatccggggcgggcgccggccgag ccggagagtgtcgaggccgggctgccggagaacgtcacgcgagcgctgggcgaactggcc cgtgccaagggattgacgctgaacacggtggtgcagggcgcgtgggcactggtgctggcg cagctgaccgggcggacggacgtggtgttcggggcggcggtgtcggcgcgtccgccggac cttcccggcgtggaggggatggtggggctgttcctcaacaccgttcccgtgcgcgtgagc ttgcaggcttcgacgccggtcgccggattgctgacggagctgcagaagcggcagtccgcg ctcatccccgaccagtacgtggggctggcggacatccagcaggcggccggtcccggcgcc gtcttcgacacgttgatcgtcttcgagaagttccaccacgattccggggaattgggctcc gccgagaccttcggcgtccgggtgcatcagggccgcgtggccgcccactatccgctgacg ctggtcgcggtccccggcgagtcgatgtacttcaagctggactatctgaccgacctcttc gaccgggacaccgcgctcgcgatcatcgagcgtttcaccggggtgctgcgcctgctgacg gacgcgggcgaggccacggtcgccgacatcgaggtgacgagcccggccgagcgcgccttg gtggtcgacgcctggggcacgtcgtcccaggcggcgccgaaccggacggcgccggaactg ttcgacacacaggtggagcgccaccgcgacgagccggcgatcgtcgacggcgaccgggcg ctgtcgtacggagaactcgccgagcgcgcggaacggctcgccggtcacctgcacggcaag ggagtccggcgcggcgaccgggtggccgtggtgctggaccggtcacccgagctgatcgtg acgttgctcgcggtgtggaaggcgggcgcggcgtacgtgccggtggatcccgcctatccg gtggaacgcgtgcagttcatgctgacggattccgggcccgcggcggtggtgtgcgcgaaa acgtaccgggacgccgtgctggacgtcggcctcgaaccgatcgtgctggacgatccccgg acgcggcgggcggtggaggagagcgctcgccggtcgaccgccacgagcggcctcgacctc gcctacgtgatgtacacgtccgggtcgacggggacgccgaagggggtcgcggtgtcgcac ggcgacgtcgcggcgctggccggggaaccgggctggcgggtgggccccggcgacgcggtg ctgatgcacgcttcgcacgccttcgacatctcgctgttcgagctgtgggtgccgctggtg tcgggcgcacgggtggtcttggccggagcgggcgcggtggacggcgaggcgctggcgcgt cacgtcgccgacggcgtcacggccgcccacttgaccgcgggggccttccgcgtgctggcc gaggaatcgccggaatccgtcgccgggctgcgcgaggtgctgaccggcggcgacgcggtg ccgctttcggcggtggagcgcgtgcggcgggtgtgcccggacgtgcgggtgcggcatctc tacggcccgaccgaggccacgctgtgcgcgacgtggtggctgctcgaacccggggacgag ccgggttcggtgctgccgatcggacggccgctcgcgggacggcgggtctacgtgctcgac gcgttcctgcggcccgtgcccgcgggggtgcccggcgagctgtacctcgccggagccggt gtggcgcaaggctatctggaccgtccggcgttgacggccgagcggttcgtcgccgatccc ttcgcggccgacgggcggatgtaccgcaccggggacctggcgtactggacggatcagggc gcgctggcgttcgccgggcgcgccgacgaccaggtgaagatccgcggctatcgcgtggaa ccgggcgagatcgaggtggtcctcggcggtctgccgggggtggcgcaggccgtggtgctc ccgaggggcgagcatctgatcggctacgtggtcgccgaagcggggcaggacgccgacccg gagcgcctgcgcgggcagctcgccgagaccttgcccgaattcatggtcccggccgtggtg ctggtactggacgccttgccgttgacggtcaacgggaaggtggaccggcgggccttgccc gaaccggacttcgcgtcgaagtcggcgggccgggaaccggtcaccgacgccgaacgagtc ctttgtggagtgttcgccgaagtcctcggtctcgaccgggtcgggatcgacgacagcttc ttcgaactgggcggcgactcgatctcgtcgatgcaggtcgccgctcgcgcccgtcgtgag ggcatcccgctgacgccgcggcaggtgttcgagcaccggactcccgagcgcctcgcggtc ttggcgcgggagaccgccgcgacgccgcgcgccgaggccgtcaccggcgtgggggagatc ccgcggacgccggtgatgctcgcgctcggagacgacgcgctgcgccccggtttcgcgcag gtgcgcgtcgtcgtcgctccggcgggcctggaccaggacacgctggcgagcgcgctgcag gcggtgctggacacgcacgatctgctgcgggctcgggtggagccggacggacggctgatc gtgcccgagcgcggcgcggtggacgcggccggtctggtcacgcgggtggccgctggaact gcggaactcgacgaggtcgccgagcgcgagctcaggacggcgacgggcacgctggacccg tcggcggggatcatggcgcggctcgtctgggtcgacgccggggacgccgggccgggacgg ctggccttcgtggcgcatcacctggccgtcgacgcggtgtcgtggggaatcctgctgccg gatctgcggacggcttacgacgagctgatctccggccggacccccgccctcgaagcaccg gcgacgtcgtaccggcagtgggcgctgaggcaggtcgagcaggcgcacagcgagcgcacc gtggccgaactcgaggactgggccgccctgctggacggcgcggacccggccggggaagag gacaccggacagtcgtattcgtggtccacgcgactgaccggcaccgaggcgcgcaacctg gtgacgctcttgccgggcgcgttccactgcgggatccaggacgtcctgctggcgggactc gccggtgcggtggcgcgggtacgcggtaccggcgccgggctgctggtggacgtggaagga catgggcgcgaagccgccgacggcgaggacctgctgcgcaccgtcggctggttcaccagc gtccacccggtccgcttcgatctgtccgatgtggacctcgcggccgccggatcgttgctg aagaccgcgaaggaccagatccgcgccgtgcccggcgatggatccggctacgggctgctg cgtcatctcaaccccggcaccgcggcgacgctggccgcgctgccgtccgcgcggatcggc ttcaactatctcggccggaccgtcctcgccccggaggacaccgcgtgggagccggacggc gaagggccgctcggcggcggtccggacatggtcctcgcgcacgccgtggaggtcagcgcg gaggtccaggacacgccgtccggaccccggctggggttggccatcgacgcccgggacgcc ggctccggcctggtgcaacggctcggtgaggcgtgggcggagacgctgagcgccctcgcg gcgctcgccggggatcccggcgcgggcgggcacacgccgtccgacttcgccctcgtcggc ctgacgcggcgggacgtgacggaactggaaacggcggcgccggggctgaccgacatctgg ccgctgtcgccgttgcaggagggcatgctcttcgagcgggccttcgacgccgacggcgtc gacgtctaccagagccagcggatcctgggcctcgacgggccgctcgacgcggaacggctg cgcgaggcttggacgcgggtgctcgcccggcacgaatcgctccggaccggttttcatcag ctggggtccggcgagacggtgcaggtcgtcgtgggggaggccgaactcccttggcgcgtg gtggatctgtcgcacctcgacgaggcggccgcggccgcggagatcgaacggctcctcgcc gaggatcaggacaggcggttcgacgtgacccagccgccgttgctgcggctgtcgctgatc cggctcggtgccgaccggcaccggctcgtgctgacgtcccaccatgtcgtgctggacggc tggtcgacgccgctcgtcgtgggtgaggtgtcggccgcgtacgcgggcgggcagctcccc gcgaaggcgccgtccttcaaggactacctggcgtggctgggccgccaggacgccgacgcg acccgggcggcgtggcgggccgagctcgacggcgcggacgaaccgtcccttgtggacgcc gacgcggacaagacgatggtgatgcccggggagcacgccgaactgctgtccgaggggacg acgcgcgcgctcaccgaactggccagggccaacggggtgacgacgagcacgatcctgcag gccgcctgggcgctggtgctggcgcggctcgcgggccggacggacgtggtgttcgggtcg gtggtggccggccgtccggcggaggtgccggacgtcgaacgcatggtggggatgttcatc aacaccgtcccggtccgggtgcggctcgacggcgggcagccggtgctggagctgatccgg gagctgcagggacgcctggcggcgttgaccgaacaccagtacctcggcctgccggagatc cagaaggcggtgggcacgggcgcggtcttcgacaccatcgtcatgatcgagaactacccg cacaccgccgacggtctcggcgacgacggcggggtcgcgatcagctcggtcgtcacccgc accggcaccggttatccgctgaccatgaacgtcagcctcgggagccgcctgcggatcaac gtgtcctaccggcccgaccggatcggcgccggcacggccgccgaggtcgcccggcaggtc gtgcgggtcctggaccaggtggtggcacggccttcgctgccggtgggccgcctcggcgtg acgagcgaaccggcgcgcgagtcggtggtggaacgctggaacgcgacgggcgacgcggcc gacacgacgtcggtactggagttgttccggcgtcaggccgtcgcctcgccggacgcggtg gcggtcgtggacggggaacgcaccctgtcctacaccggcctcgaccgtgaatccgaccgg ctggccggatatctggccgccgtcggggtgcggcgcggtgaccgcgtcggtgtggtgatg gaacgcggcgcggacctcctcgtcgccctgctcgcggtctggaaggcgggtgccgcgcag gtaccggtgaacgtcggctaccccgcggagcggatcgagcggatgctggccgacgccggg gtgtcggtcgcggtctgcctcgaagcgagccgcaaggcggtgccggacggggtcgagccg gtggtcgcggatctgccgtcgctcgacgggacacggcacgaggcgccacgggtcacggtc ggggcgcacgacgtcgcctacgtcatgtacacgtcgggatcgaccggggtgccgaagggt gtcgcggtgccacacggaagcgtggcggcgctggcgagcgacccgggctggtcgcagggc cccggcgatcacgtactgctgcacgcgtcgcacgctttcgacgcgtcgctggtcgagctc tgggtgccgctggtcagcggggcccgcgtggtggtcgcggaaccgggcaccgtggacgcg gagcggctccgcgaggcgatcgcccgcggggtgaccaccgtccacctgacggcgggtgcc ttccgtgcggtggccgaggaagcgccggactccttccgcgggctgcgggagatcctgacc ggtggggacgcggtcccgctcgcctccgtcgaacggatgcgccgggcctgccccggcgtc cggttccggcagctctacggtccgaccgagatcaccctctgcgccacctggctcgttctc gaaccgggggcggaaacgggggacacactgccgatcggcggaccgctggcgggtcggcgg gcctacgtgctcgacgcgttcctgcagccggtggccccgggtgtgaccggtgagctctac ctcgccggagcggggctggcgcacggctacctcggcaacccggtgtcgacttcggagcgg ttcgtcgccgatccgttcgcccccggagagcggatgtaccggaccggcgacctggcacgc tggacggaacagggccagctgctcttcggcgggcgtgccgacgcccaggtgaagatccgg ggctaccgggtcgaacccggcgagatcgaggcggtgctgaccgagatccccgacgtcgcg caggcgatcgtggtggcgcgggaggaacgccccggcgaaaagcggctgatcgcctacgtg accgcggaaccgggacagggactggaatccgccgcggtccgcgcgcagctcgcggcccgg ctgccggagttcatggtgccgtcggtggtgctggtgctggacggtttcccgttgaccatc aacgggaagatcgaccgcgcggccctgcccgcccccgaattcgtcccggcggcggccggt cgcgaaccgcgcaccgggaccgaacgggtgctgtgcgacctgttcgccgaaatcctcgga ctggaccgggtcggcgccgacgacggtttcttcgaactgggcggggactcgatcctctcg atgcggctggccgcccgcgcgcgccgcgagaacctcgtgttcggggcgaagcaggtcttc gaccacaagacgcccgcggggatcgcggcggtcgccgagcacggcggacggacgcgggcc gaggacggcgagggcgtcggcgaggtcccgttgacaccggtggtgcgggcgctgctcgaa cgcgaccccctcggactgacccgcggcggcatggcgcagtgggtgatcgtggacgtgccc ggcgacctttccgtgaccgccctggccgccggactgggcgcggtgctcgacacccacgac ctgctgcggagccggctcgtcgcgaccgagggcgaggagccccggctggtcgtggccgac cggggaaccgtcgacgcggcgacgctggtcgagcgtgccgccgcgggcgacatcgacgaa atcgcgagtgacgcggcggcacgcctggatcccctcgcgggcgtgatggtgcgggcggtc ctggcggacgccgggcggctcgtggtggccgcgcatcacctcgtggtcgacgtggtgtcg tggcgaaccctgctgccggacctgcaagcggcctgcgaggccgcagtcgccggcctgcgt ccgtcgctcgaagcgccggacgtctccttccggcgctggtcgcggacgctgaccgaagag gcggcgaaccggaccgccgagctggcgacgtggacggagatcctcgacggggcaccgcgg cggctcggcgagctcgatccccggcgtgacaccgtgtcgaccgcgggccgccggacctgg acccggccggcgggcacgctcgcggacaaggcgacctcggccttccactgcggtgtccac gaggtactgctggccaccctggccggcgccgtgaccggctggcggggcggcaccgccgtc gtcgtggacgtcgaaggccacgggcgtcagcccctcggcgacatggacctgtcgcggacg ctcggctggttcaccgacgtccacccgctccggctggacacgaccggggccgacccggcc gacgtcgtcgcgggcggcgacgcggcgggccgtctgctgaagcaggtcaaggagaacgtg cgggcggtgcccgacggcgggctcggctacgggatgctgcgtcatctcaacccggagacg gcaccggtcctcgcggcgctgccgaaggcggagatcggattcaactacctcggccgcttc tccgcacgagccgacggtggcggcgagccttggcggataacgggaatcgtcggtgacgcg gcggacgatgccacgcctctgcggcacgtcctggagatcgacgccgtcgtggcggacggc gcggacggtcccgagttcagcctgaccgtgacctgggcccgccggctcctcggcgacgcc gaagccgagtcgttcgccgacgcgtggctggccgcgctgaccggcctcgccgcgcacgtc gacggcggcggcgggggacacactccgtccgacttcccgctcaccgcgctgacgcagcga gaggtggcgcggatcgaggccgccgtgccggatctgctcgacatctggccgctttccccg ctgcaggagggattgctgttccactccaccggcgaggacggcctcgacgtctacgcgagc atgcggaccctcgccctcgacggcccgctggacgccgcccggttccgcgcgtcctggcag gccatgctcgaccggcacgccgccctgcggacgagtttccaccagctcccgtccgggacg gccgtgcagacgatctcccgtgaggcgacgctgccctggcaggagaccgacctgtcccgg ctgcccgaggacgaggcgctggcggaattcgaccggctcgccgcggcacagcacgccgaa cggttcgacctggccaagggaccgatgctgcgcctgcacctggtgcgcctcggcgaacgc aggcaccggctgatcttcacgtcgcatcacatcgtggtcgacggctggtccctgccgctg ctcgccaccggcgtgctggccgtgtacgaagcgggcggcgacgcccgggcgctgcccccg tcggcgtcgtaccgcgactatctcgcctggatcgcggaccaggacaagacggcggcgctg gaggcgtggcggaccgaactggcggggctcgacgaggcgacccagatcgtgccgccggag tcgatcctcaccccgctcgcacccgaacgcgtcaggttcgccctcggcgacgagccgagc aggcgcctggcggagttctgccgccgtcacggggtcacgccgaacacgctcttccagggg atctgggccctgcacctggcccggctgaccggacggcgggacgtggtcttcggcgccgcg gtggccgggcgtccggccgacatccccggggtggaggccgcggtcggcctgttcatgaac atgctgccggtccgggcgcgcctcgtcggcaccgaaccggtcgtcgacatgctgaagaac ctgcaggagcggcagttcgatctgctgccgcatcagcacctcgggcagggagagatcatc aaggcggcaggccggggcgcggcgttcgacacgatcctggtgttcgagaactatccgccc ccgccgccccggctcgacggccccgacgcgctcgtcttgagccccgcggggaactcggac gacgacgggcactatccgttgtccctgcgtgcttccgtggcgggaggtccggtccgcggt gaagtgatctaccggccggacgtgctcgaccgggccgaggccgaggagacggtcgcgacc ctcctccgcgcactcgagcaggtgctggccgaaccgcggacgccggtggggcggatcggc ctgatcggcccggagcagcgccgcctggtggtggacgagtggaaccggaccggcaggccg gtcaccgagaagacgctgccggtgctgctgcgcgaacaggcggagcggacgccggacgcg atcgccgtccaggacgcggcgcgaggcctgtcgtaccggggattggtcggcgaagtggag tcgctggcgcggctgctcgccgaggcgggcgtgcgacgcgaagcccgggtgggggtgctg gtcgagcgttcggccgacctcgcggtgaccctgctgggggtcatgttcgccggcggggcg ttcgtgccggtcgatccggactatccgcgtgaccgcgtcgaattcatgctggcgaactcg gcgcccggggtgctggtgtgcacgaaggcgacccggtcgttcgtgcccgcggagttcgcg ggcacggtgctggtgctggaggacctgcccgccgccggtccggacgccgccctgcccgag ccggcgccggaagacgcggcgtacgtgatctacacgtccggctcgacgggcgtgccgaag ggtgtcttggtcacccactccggactcgtcaacctcggctacgcgcatatcgaacggatg gcggtgacgtcgtcctcacggatcctgcagttgtccgcgatcggcttcgacgccatggtg tccgagctctacatgtccctgctggcgggggcgaccctggtcctgccggacgcggcgagc atgccgccgaaggtgacgctgggcgacgcgatccggcaggcggagatcacgcatctgacc gtgtcgccgagtgtgctggcgagcgaggacgacctgccggacacgctgcggacggtgctg acgggcggcgaggcgctcccggccgcgctggtggaccgctggtcgccgggccgccgggtg atccaggcctacgggccgaccgagaccaccatctgctcgacgatgagcgccccgttgtcc ccgggacacgaccaggtcccgctcggcggaccgatccacaacgtggggcactacgtgctc gacgcgttcctgcggccggtgccgcccggtgtggtcggcgagctctacatcaccggtgtc ggactggcccgcggctacctcggccgtcccggcctgaccgcggaacggttcgtcgccagc ccgttcgcgcccggcgagcggatgtaccgctcgggcgacctgttccgctggacccgggaa ggccagctgctcttcgccggtcgggtcgacgcgcaggtcaaggtccgcggctaccgggtc gagcccgccgagatcgaggccgtgctcgcggagcatccgtgggtcggccaggtggcggtc tccgtccgccgggacgggccgggcgacaagcggctggtggcctatgtcgtgccgtcggcg gccgccggcgaggggaacggcacgctggccgccgcgctgcgggagctggccgccgaacgc ctgccggagtacatgatgcccgcggcgttcgtgtcgctggagaagatgccgctcaccccg aacggcaaactcgatcaccgggcgctgcaagcccccgacttcgccgggacgtcggcgaaa cgggagccgcgcacggccgcggaggcggcgctgtgcgcgctgttcgcggacgtgctgggg ctcgaccaggtggctcccgaggacagcttcttcgaactcggcggcgactcgatcacctcg atgcagttgtcggcgagggcccgccgtcaggggctggaactgaccccgtggcaggtgttc gaggagaagacgccggaacggctggcgccgctcgtccaggaactcccggccgaggacgcg cccgtcgcggtaccggagcccgccgacggcacgctactcgccctttcccctgaccagatg gacctactcgaggccgggctggccggcgaatga

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