Amycolatopsis keratiniphila: AORI_2294
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Entry
AORI_2294 CDS
T02678
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
aoi
Amycolatopsis keratiniphila
Pathway
aoi00300
Lysine biosynthesis
aoi00550
Peptidoglycan biosynthesis
aoi01100
Metabolic pathways
aoi01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
aoi00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
AORI_2294 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
AORI_2294 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
AORI_2294 (murF)
Enzymes [BR:
aoi01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
AORI_2294 (murF)
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Paralog
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AGM04882
UniProt:
R4T1M4
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Position
2455451..2456971
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AA seq
506 aa
AA seq
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MIVLSLAEIAAIVGGRLHRTDGTAEVTGSVEFDTREVTPGGLFIALPGAKVDGHDFAARA
VEAGAVAVLAAREVDAPAVIVPPLAAGEGHERAFALVSDKDGAGAAVLAALAKLARHVIQ
KLAGDHLTVVGVTGSAGKTSTKDIIAQLLEPLGPTVAPPGSFNNELGHPWTALRADDSTR
QLVLELSARGPGHIAELAAIAPPRIGVVLNVGTAHVGEFGSREGIAKGKGELVEALPSAE
DGGVAVLNLDDPYVAAMASRTKARVVFVGESESAQVRAADITLDGEARASFRLVTPDGEA
PVKLPLYGEHQVGNALSAAAVALEMGSTVEEVAARLSSLERRSERRMEVTTRADGVTVLN
DSFNASPESMRAALKALASMSANRRSWAVLGVMGDLGENSVEAHDGIGRLVVRLNIDKLV
VIGQAAAAAHQGAQQEGSWGEESVLVPDVDAAIALLHDQLRAGDVVLVKASKAAALWRVA
DAVLAAPVTDAESLSPSHERSNGGDA
NT seq
1521 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgtgctcagcctggccgagatcgccgccatcgtcggcgggcggctgcatcggacc
gacgggaccgccgaggtcaccggaagcgtcgaattcgacacccgtgaggtcactcccggt
ggtctattcatcgcgctgcccggcgcgaaggtcgacggccacgacttcgccgcgcgggcc
gtcgaggcgggcgccgtcgcggtgctcgcggcccgcgaggtcgacgccccggccgtgatc
gtgccgccgctggcggccggcgaggggcacgagcgggcgttcgcgctggtctcggacaag
gacggggcgggtgccgcggtgctggccgcgctcgccaaactcgcccggcacgtcatccag
aagctcgcgggtgaccacctgaccgtcgtcggggtcaccggttcggcgggcaagacctcc
accaaggacatcatcgcccagctgctggagccgctcggcccgacggtggcgccgccgggc
tcgttcaacaacgagctgggccacccctggacggcgctgcgggccgacgactcgacacgg
cagctcgtgctggagctctccgcccgcggacccggccacatcgccgaactggcggccatc
gcgccgccgcggatcggggtcgtgctcaacgtcggcaccgcgcacgtcggcgagttcggc
tcgcgcgagggcatcgccaagggcaagggtgaactcgtggaggcgctgccgagcgccgag
gacggcggtgtcgcggtcctgaacctcgacgacccgtacgtcgcggccatggcgagccgg
acgaaggcccgcgtggtgttcgtcggcgagagcgagtccgcgcaggtccgcgccgccgac
atcaccctcgacggcgaggcgcgcgcgtcgttccgcctggtcaccccggacggcgaagcg
ccggtgaagctgccgctctacggcgagcaccaggtcggcaacgcgctcagcgcggccgcc
gtggcactggagatgggctcgacggtcgaggaggtcgccgcccgcttgtcgagcctcgaa
cgacgctccgaacgccgcatggaggtcaccacgcgggccgacggcgtcacggtcctcaac
gactctttcaacgccagccccgaatcgatgcgggccgcgctcaaggcgctcgcgtcgatg
agcgcgaaccgccgctcctgggccgtgctcggcgtgatgggcgacctcggcgagaactcg
gtcgaggcgcacgacggcatcggcaggctcgtcgtccggctcaacatcgacaagctcgtg
gtcatcggccaggccgccgcggccgcccatcagggcgcgcagcaggagggttcctggggc
gaggagtcggtactggtacccgacgtcgacgccgccatcgccctgctgcatgatcagctc
cgcgcgggagacgtggtgctggtgaaggcgtccaaggccgccgctctgtggcgggtggcc
gacgccgtgctcgccgctcccgtaaccgacgctgaatccctttccccctctcacgaacgc
tcgaacggtggtgacgcgtga
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