Amycolatopsis keratiniphila: AORI_4678
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Entry
AORI_4678 CDS
T02678
Name
(GenBank) non-ribosomal peptide synthetase
Organism
aoi
Amycolatopsis keratiniphila
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Condensation
AMP-binding
PP-binding
AMP-binding_C
PapA_C
DUF7454
Motif
Other DBs
NCBI-ProteinID:
AGM07262
UniProt:
R4T8K0
LinkDB
All DBs
Position
complement(5169522..5187086)
Genome browser
AA seq
5854 aa
AA seq
DB search
MTVLDTTAAPRAERAVALPELFAARVRSTPDAVAVDGHGGRLTYAGLADRAARLAARLVR
LGVRAEDRVGLLLERSAELVVAELAIVMAGGVYVPLDRRAPDDRSRLVLATAGVSVLITD
EPERAARIHSGRIVVAGRSLAPPDVVLPRVDADQLAYLMHTSGSTGTPKGVAVRHRDVAV
LAADSRFAGGAHRRVLLHSPAAFDASTYELWVPLLGGGTVVIAPPGEPDVEMLRDIVGRY
EVTSLWLTAGLFRVVAQEAPDCFLGVEEVWTGGDVVPAAAVRRVLGACPGLTVTDGYGPT
ETTTFATSRPMSTKDGVSDPVPIGRPLDGVRAHVLDEALNAVPAGTAGELHLSGAGLARG
YWGRPGATADRFVADPGVPGGRMYRTGDLVRYNDDGELEFLGRADDQVKVRGFRVELGEI
ESVLAAAPGVGEVVVVARERKPGVKRLVAYVVPRPGEALDDLAATAAAVLPDYMVPSAFV
VLDALPLNANGKVDRRALPAPPEESRTDTEPRSETERAVADVLAGVLGMDRVASDDDFFA
LGGDSLLAVQALSRLRRTFGVTLSARAVFDAPTVSGLARLVDEAQPAGNDAIPAAPPTRV
IPLSPAQRRLWFLDELTGDSAEYNTAVGLRLSGPLDVDALRGALAALCARHESLRTTFDG
CAQRIADTAEIPLRVEETAADDDTLAADLSVPFDLRSGPLTRATLYREGPEEHLLVLCQH
HIVTDGRSIGILTGELLDFYAGITPPPLESGYRDYTHWRLQTDDDAQLGYWRAALDGLEP
LAFPTDRPRPAQRGTAGAVHRHDLPSDLVRGLTEVGRPHGATLFMTLTAAVQLLLSAYGG
QRDIAVGTAVSGRDRPEWEPLTGFFVNTLVLRSHIDRARPFPEFLAGFRETALEAFAHAD
VPFDRVVEAVQPERDPSRTPLVQAVVVLQSPLVRPREAAGLRVSEYDLPRPSARFDLVVE
FWPREDGLRITVEYATALFDGATIERLTTSLEALLTGIAADPGRPVGELPLLTEADRRLL
ASPDPAPSTTITRLFDQHAERHPQAPAVLFGDDRLDYGELRAEADRLAGRLIELGVRPED
RVGVLMDRSADLVVALLAILKAGAAYLPLDLRAPADRLRLLLDGTSLLLTDETWHGTAAT
VHSGRILTLPATGDAATVTVEPANLAYVEYTSGSTGVPKGVAVRHADVVALATDPRFTGG
AHERVLLHSPLAFDASTYELWVPLLNGGTVVIAPPGDVDAEVVRDLTARYGVTALWLTAG
LFRLFAGDTPECFRGLREVWTGGDVVPPEAVRRVLESCPGVTVVDGYGPTETTTFATSFR
MTSAEAVPETIPIGTPLTGMRVYVLDDGLRPVPRGALGEICVAGPGLARGYAGRPGATAD
RFVACPHGAPGERMYRTGDRGRWRTDGTLEFAGRADDQLKIRGFRVEPGEVERALTARPE
VAEAVVTARTGSGRKHLVAYVVAGEGSTVDTGTLRESLGRTLPDYLVPSAFVVLDALPLN
ANGKVDRRALPEPVFEPAASGGTAPRTEREAVLAGIWADVLGLDRVGVEDNFFALGGDSI
LGIQVSARARKAGLSITTADLFLHQTIAALAPALTGVSTVPDHGPVTGDVVPTPIQRWFF
DTISEPARFDQAIAVELAKGTDEVALAAAIDAVIEHHDALRTTFTRDGDRWRLRIAGVED
GHSLLRWRLSGPPERRVLHLSAHHLAVDGVSWRILLDDLDQAYRKADLGPRTTSFQDWAT
RLSTYTEQGGFDDELEHWRAIPEVAPIPVDGIGTNTVGRARAVTVRLTAGETRSLLRQVP
EVYRTQVNDVLLTALGRTLRDWTGRVPVIDLEGHGREELFDGVDLSRTVGWFTSLFPVAL
DVPDEWGAALKVVKERLRAVPRRGIGYGALRYLSGTAPAIDPQISFNYLGQFELTGELYT
GSPGELSLAADPGGVRPHLLDVVGQVTGDTLEFTWHYAEGVHEEVTVTRLAEGMLENLRG
LLGHCAEPGAGGRTPSDFPLAGLDQSTVDELVGDGRDVEDVYPLTPMQAGMLFHSLARPG
DRNYFEQITFIVDDVPDPRALVAAWQRVVERTPILRSRLVWAGVPRPLQIVRRSAEIPVS
CPDWSTVDAEEALRRRLAEDLAEGLDLTRAPLTRLVVAKESATSVRVIWTFHHVLLDGWS
VFGVLSDVLAVLRGEEPPVRRPFRDYAGWLAAQDDEAAEAHWRAELAGVTPTPLPGDRGA
RAHAASSSARVPVDFDDTTTARINAFARRHHLTLNTIVQGAWAALLSRYSGESEVCFGAT
VSGRPVELPGADDIAGLFINTLPVRVRLDAGRGLVDWLRELQAAQAESRRFGHVGLPRLQ
SWSDDGGSLFDSIIVFENYPVGDVAGVRDVRAAERTNYPLGVVAYPGRRLSLMLTHDPEL
IGPDLARRLAGHLETLIRGFVDTPYDPVTRVPMLSEREIRHLLRERSATVRRIPEGSVPE
QFEARARRNPDGVALVTDEETVTYGELDVRANRLANRLRALGVRAEDRVALLMDRSPALV
VAELAILKAGGAYLPLDLRAPTERLRLLLSEAEADVLVTDEAWLSIAEEIHDGAIVMDAG
DAPEASPVVPVDPEQLAYVIYTSGSTGKPKGVAARHRDVLALAADQRFAAHDRVLLHSPQ
AFDASTYELWVPLLNGGTVVLAPPGELDVHTLGRVIAAHAVTGVFMTTGLFRLVAQEAPE
TFAGVREVWTGGDAVPAVALRRVRAACPRTLVADVYGPTETTTFATVHPLPDEVPDVVPI
GAPLDNTRAYVLDDGLRLVPPGAPGELHLAGAGLARGYLGRPGLTADRFVADPFGPPGER
MYRTGDVVRWNDEEALEFVGRVDEQVKIRGFRVEPSEIEAALGEHPGVEQAAVLARADGG
VKRLVAYVVGETEGLGEFLGRTLPDYMVPAAFVRLAKFPVNVNGKLDRTALPAPDFGARD
HVAPRTDRELVLAGIWAEVLGVERVGATDDFFELGGDSILSIQVVSKARRAGLELLPGDL
FAHRTPAALAAAARSATEAVRRGPVSGEVPLTPIQRWFFATQTADPEHFHQFVRLGPARI
DRAAARKAVDALLEHHDALRMRFTHEDGWKQENGPVGAETPLIRLDLSEHGVTLAVHHLV
VDGVSWRVLAEDFDRGYAQALRGEAIDLGPRTTSFREWAIRLAEHTAGGGFDDELDHWHG
LPADTSIPVDGEGEATVASMREVTVRLPEAETEALLREVPAAYRTQVNDVLLTALGRVLR
DWTSKVPVIDLEGHGREDLFDDVDLSRTVGWFTSVFPVALDVPEDWGTALKSVKEQLRAV
PRRGIGYGALRHLAGTAPSIDPAVSFNYLGRFTSGRLESDESELSARAHLLDVVGRVESG
ELELTWYYTEGVHHESTVDRLAEAMLTALREIIAHCTEPEAGGRTPSDFPLLALDQSTVD
TLVGDGRAVEDLYPLTPMQVGMVFHSLSQPDERLYFQQVGFVVEGVDDVDALAEAWQHVV
DRTPVLRTRIAWEGVPEPVQVVRRRVTVPVNRLDWRAHSAAGQERFWQEVLAADRAEGLD
LDGETLLRLTLARLSDTEVRVLWTFHHVLLDGWSVFGVLSDVFAAYSGGELPERPPFRDY
VAWLDRQDDTEAERHWRRELGDFTARGRLTAQDHTSRSAEWLRVPVESSARLAEAARKAG
LTMNTVLQGAWALVLSRLTGERDVCFGTTVSGRPVDLTGADDITGIFINTLPVRVTTDRS
PVARWLAALQDRQVESRRYGHLPLTKLQAWSGSDGSLFDSIVVFENYPIDSATRDGLRLR
DVDAAETTNYPISVVASPGERLSLDVGYDPDLFDAATAERITDQLVGVLDAFAEDLNRPL
DSIDLLTDAERLQILGDWNDTAHPLPEGSLAELFGRQVARAPGAVALVGDGVRLTYADLD
ERADRLARRLVSLGAGPETVVGVLMDRSPDLVVAELAVVKAGAAYLPLDTRAPAPRLKTL
LDGVPILVTDRTRAESVVHSGQIVVPDGRTADVALPGAAPDNLAYVMYTSGSTGRPKGVA
VRQRDVVALAADRRFAAHERVLLHASPAFDASTYELWVPLLNGGTVVVAPPGDLDVDTLR
RVIAEYEVHGAFFTAGLFRLLAQEAPETFRGMREVWAGGDVVPAAAVRRVREACPGTVVV
DGYGPTETTTFATSHPIPDDVTGPVPIGKPLDNMRTYVLDAELRLVPQGVPGELYIAGAG
LARGYFGDPALTADRFVPDPFGPPGERMYRTGDLVRWNPLGELEYTGRADEQVKVRGFRI
EPAEIEAALTAHPGVGQASVLTREDHGVKRLVAYHTGDADGLAEFLGRTLPDYMVPSVFV
RLDRFPLTANGKVDRRALPAPDFGEKSAGTAPTTEAERALAGIWSDVLGVADVGAEANFF
ELGGDSILSIQVVSRARRAGLNLLPHDVFRHPTLAALAAHAGGDAGPRAEQGPVTGTAPL
TPIQHWYFDGLPDRFDQRVVLEFTEDVDEAALRRALEAVWAHHDGLRLRFGRDGVQHGEP
VWPAELLTDEIAFDLGRGPLLAAVLDGRRLTLAAHHLVVDGVSWRILLEDLETAYRGGEL
GPKTTSYLEWARRLAEHAESGGFDDELAYWREIPALPDDGEPATIADTGEVTVRLTAEET
RALLQEVPEVYRTQVNDALLAALGRVLRDWTGQTPVIDLEGHGREDLFDDVDLSRTVGWF
TSMFPVALDVPEDWGAALKAVKEQLRAVPRRGIGYGALRYLTGTAPAIDPRIGFNYLGRF
EDAEAGAFRTGALDADVDPAAPARHTLDIVGRVVAGTLELTWAHVETRHDRGTVEELAER
MLAALREIIAHCAAPEAGGRTPSDFPLATLDQSTVDKLVGDGRAVEDVFPVTPMQGGMLF
HGLSQTAQGMYVEQATFVLEGVTDLDRLATAWQRVVDRTPVLRTAFVWAGVEEPLQVVHR
EVRLPIRVLDGTGHDLQRLLAEDREQGLDLAEAPLMRVALVRLSETEVQVLWTFHHALLD
GWSVFHVLSDVCGAYAGQTLPTRPPFRDYLAWLGRLDRTDAERFWRRTLSGIDGPTPVPG
DRAPAAGHIACSSEWLPVRLDEAATSGLDEFVKRHGLTHNVVLQGAWALLLSAYSGHDDV
VFGSTVSGRPPEVTGVDAITGIFINTLPVRVGIDRGARVAEWLADLQASQAEARRHGHLP
LALVQGWAELPGGVNLCESLVVFENYPITGAEAGHGLTVRDLSARETTNFPLTVVASPGR
ELNVDLGYDPALFDAETVSRLAGHLLTLLRELTVDGARAITDVSMLTTEDELLLARWTET
GTAAPARSLPDLFAEQVRARPDAVAAVLDGESVTYAELNRRANRLANRLIGLGLRPEEPV
GLATSRAGTVVAELAVVKAGGAYLPIDTRAPAERRQVLLEGVRFVVSDTEYPDAIRLSSV
DDEPDGDPAVVVDPDQLAYVMYTSGSTGTPKGVAVRHRDVAALAVDSRFRGGAHERVLLH
SPAAFDATTYELWVPLLTGGRVVTAPDGGLDAHRLRTLIREHGLTGMWVTAGLFRVLAQE
SPDCFAGLREVWTGGDVVPAEAVRRVLGACQGLRVVDGYGPTETTTFATAHPMDETVPDR
VPIGTPLDGMVARVLDPELRPVPPGMPGELYLAGAGLARGYRERPGLTADRFLAAPGGQR
MYRTGDVVRRTRAGTLEFLGRADDQVKLRGFRVEPGEVEAVLARHPAVAQAAVVVREDQP
GAKQLVAYVVSEAGQDTLRDFLADRLPDYLVPSAFVALDRIPVSANGKLDRKALPAPAAP
ETGYVEPETETEQALAAIWAEVLGVERVGAEDNFFALGGDSLRSLHIAAKAGALFAVRLT
PADILTARTVAGLAGTVEELILGELESLASETEA
NT seq
17565 nt
NT seq
+upstream
nt +downstream
nt
atgaccgtgctcgacacgacggccgccccccgagccgaaagagccgtcgccctgccggaa
ctgttcgccgcgcgggtgcgctccaccccggacgcggtcgccgtggacggccatggtgga
cggctgacctacgccggactcgccgaccgggccgcccgcctcgccgcccggctggtccgg
ctcggagtacgtgccgaggacagggtcgggttgctgctcgaaaggtccgccgaactcgtc
gtcgccgagctggcgatcgtgatggcgggcggggtctacgtgccgctcgaccggcgcgcc
cccgacgatcgctcgcggctggtgctggccaccgcgggtgtctcggtgctgatcacggac
gagccggagcgtgccgcgcgaatccacagtggacgcatcgtcgtcgcgggacggtcactt
gcgccgccggacgtggtgcttccacgtgtcgacgcggatcagctggcgtatctcatgcac
acgtcgggctcgacagggacgccgaagggagtggcggtccggcatcgggatgtcgcggtg
ctggcggccgacagccggttcgcgggtggcgcgcaccgccgtgtcctgctgcattccccg
gccgccttcgacgcgtcgacctacgagctgtgggttccactgctcggcggcggaacggtg
gtgatcgcgccgccgggcgagccggatgtggagatgctgcgcgacatcgtcggccggtac
gaggtcacctcgctctggctgaccgccgggctgttccgcgtcgtggcacaggaggcaccg
gactgtttcctcggtgtggaagaagtgtggaccggcggagacgtggtcccggcggccgcc
gtccgccgggtgctgggcgcctgccccgggctcaccgtgaccgacggctacggtcccacc
gaaaccaccaccttcgccacctcgcgtcccatgtccacaaaggacggtgtgtcggacccc
gtgccgatcggccgcccgctggacggcgtccgcgcccacgtcctcgacgaggcgctgaac
gccgtcccggccgggacggcgggggagctgcacctttccggggccggtctggcccgtggc
tactggggcagaccgggtgcgaccgcggaccgcttcgtggccgatcccggcgtgcccggc
ggccggatgtaccggaccggcgatctggtgcggtacaacgacgacggcgaactggagttc
ctcggccgggcggacgaccaggtcaaggtccgcggtttccgcgtcgagctcggcgagatc
gaatcggtgctggccgccgcgccgggcgtgggcgaggtcgtggtcgtcgcccgcgagcga
aagccgggcgtcaagcggttggtggcctacgtcgtgccccggccgggcgaggcgctcgat
gatctcgcggcgacggccgcggcggtgttgccggactacatggtgccgtcggcgttcgtc
gtcctcgacgcgcttcccctcaacgccaacgggaaggtcgatcgccgcgccctgcccgcg
cccccggaagagagccggacggacaccgagccgcgctcggagacggaacgtgccgtcgcc
gacgtgctggcgggcgtgctcggaatggaccgcgtcgcgagcgatgacgatttcttcgct
ctgggcggcgattcgctcctcgcggtgcaggcgttgtcccggctgcgccggaccttcggc
gtgacgttgtcggctcgcgccgtgttcgacgcgcccaccgtgtcgggactggcgcggctg
gtcgacgaggcgcagcccgccgggaacgacgcgatcccggccgcaccaccgacgcgggtg
ataccgctctcgcccgcccagcggcgcctgtggttcctcgacgagctgaccggggacagc
gcggagtacaacaccgcggtcggtctccggctttccggaccgctggacgtcgacgccctg
cgcggtgcgctggccgcgctctgtgcccgtcacgagtccctgcgcacgaccttcgacggg
tgtgcccagcgcatcgccgacacggcggagataccgctgcgcgtcgaggaaaccgccgcg
gacgacgacacgctggcggcggacttgagcgttccgttcgacctgcgcagcggccccctg
acgagggccacgctctatcgcgaggggccggaggagcatctgctcgtcctgtgccagcac
cacatcgtcaccgacggccggtcgatcggcatcctgaccggcgagttgctggacttctac
gccgggatcaccccgccgccgctggagtcgggctatcgcgattacacgcactggcgcctt
cagaccgacgacgacgctcaactcggctactggcgtgcggcgctcgacggactcgaaccg
ctcgctttccccaccgaccgcccgaggcccgcccagcgcggtacggccggcgcggtgcac
cgccacgatctgccctcggacctcgtccgcggcctcaccgaggtgggacgtccgcacggg
gcgacgttgttcatgaccctgaccgcggccgtgcaactcctcctgtcggcctacggaggt
cagcgcgacatcgccgtcggcaccgcggtctccgggcgcgaccggcccgaatgggagccg
ctgacggggttcttcgtgaacaccctcgtactgcgctcccatatcgatcgcgcccgtcct
ttcccggaattcctggccgggttccgggagacggcgctggaggcgttcgcgcacgccgac
gtccccttcgaccgcgtcgtcgaggcggtacagccggaacgcgatccgtcgcggacgccg
ctggtacaggcggtggtcgtcctgcagagtccgctggtccgccctcgtgaggccgccggc
ctgcgggtttcggagtacgacctgccccggccgtcggcccggttcgacctggtcgtcgag
ttctggccgagggaagacggcctgcggatcaccgtcgagtacgccaccgcgctgttcgac
ggcgcgacgatcgagcggctgaccacgagcctggaagccctcctcaccgggatcgctgcc
gatcccggccgtccggtgggcgagcttccgctgctcaccgaggccgaccgccgactcctt
gcgtcgccggaccccgcgccgtcgacgaccatcacgcgtctgttcgaccagcacgccgag
cggcatccgcaggcccccgcggtgctcttcggtgacgaccgcctcgactacggcgagctg
cgtgccgaagccgaccggctggcggggcggctgatcgaactcggcgtgcgcccggaagac
cgggtcggcgtgctgatggaccgctcggccgacctggtggtggccctgctggcgattctc
aaggccggtgccgcctatctgccgctggacctgcgtgccccggccgaccgcctgcgtctt
ctgctcgacggcacgtcgcttctgctcaccgacgagacgtggcacggaaccgccgcaacc
gtccacagcggacggatattgacactgcccgccaccggggacgcggccacggtgacggtc
gaacccgcgaacctggcctatgtcgagtacacctccggctccaccggcgtaccgaagggc
gtggcggtccggcacgccgacgtggtcgcgctggccacggatccccggttcaccggtggc
gcgcacgagcgggtgctcctgcactcgccactggcgttcgacgcctccacctatgagctg
tgggttccgctcctgaacggcggcaccgtggtcatcgcgccgccgggagacgtcgacgcg
gaggtcgtccgcgacctgaccgcccggtacggtgtcaccgccctttggctcaccgccggt
ctcttccggctcttcgccggtgacacgccagagtgcttccgcggcctgcgggaggtctgg
acgggcggcgacgtcgtcccgcccgaagccgtgcgccgcgtgctggagagctgtcccggc
gtcacggtcgtcgacggctacgggccgaccgagaccaccacgttcgcgacttcgttccgc
atgacatccgcggaagcggtccccgaaacgatcccgatcgggaccccactgaccgggatg
cgcgtctacgtgctcgacgacggactgcggccggtcccgcgcggcgcgctcggcgagatc
tgcgtcgccggcccggggctcgcccgcgggtacgccggacggccgggcgcgacggccgat
cggttcgtcgcctgcccgcacggtgcacccggcgaacgcatgtaccgcaccggcgaccgc
gggcgatggcgtaccgacgggaccctcgagttcgccggccgggccgacgaccagctcaag
atccgcggcttccgggtcgaacccggcgaggtggagcgtgctctcaccgcccggcccgag
gtcgcggaggcggtggtcacggcgcgcaccgggtccggccgcaagcacctggtcgcctac
gtcgtggccggggaagggtccacagtggacaccgggaccttgcgcgagagccttggccgg
accctgccggactatctcgtgccgtcggcgttcgtcgtcctcgacgcgcttcccctcaac
gccaacgggaaggtcgatcggcgcgcgctgccggagccggtcttcgagcccgccgcgagc
gggggaacggcgccgaggaccgagcgggaagccgtgctcgcggggatctgggccgacgtg
ctgggtctcgaccgggtcggtgtcgaggacaacttcttcgccctcggcggcgactcgatc
ctcggcatccaggtcagcgcgcgggcgcggaaggcgggactgtcgatcacgacggcggac
ctgttcctgcatcagaccatcgccgccctcgccccggccttgaccggcgtctccacggtc
ccggaccacgggcccgtcaccggggacgtcgtgccgaccccgatccagcgctggttcttc
gacacgatctccgaacccgcccggttcgaccaggcgatcgcggtcgaactggcgaagggc
accgacgaggtcgcgctcgccgcggccatcgacgcggtgatcgagcaccacgacgcgttg
cgcacgaccttcacccgcgacggagatcggtggcggctgcgcatagccggtgtcgaggac
ggacattcgctgctgcgctggaggttgtccggtcctccggaacggcgcgtgctgcatctg
tccgcacaccacctcgccgtcgacggcgtgtcctggcggatcctgctcgacgacctcgac
caggcctaccggaaggccgatctcgggccgaggaccacttcgttccaggactgggcgaca
cgcctttccacctatacggaacagggcggattcgacgacgaactggagcattggcgtgcg
atccccgaggtcgcgccgatcccggtcgacgggatcggcacgaacacggtcggccgggcc
cgcgcggtgaccgtgcggctgaccgccggggagacgcggtcactcctgcgccaggtgccc
gaggtctaccggacgcaggtcaacgacgtgctgctcaccgcgctcggccggacactgcgg
gactggaccggccgggtcccggtgatcgatctggaaggccacggccgggaggaactgttc
gacggcgtggacctgtcgcgcacggtgggctggttcaccagcctgttcccggtcgcgctg
gacgtcccggacgaatggggcgccgcgctcaaggtcgtgaaggagcggctgcgcgcggtc
ccgcgacgcggcatcggttacggcgcgctgcgctatctctccggcaccgcgcccgccatc
gacccccagatcagcttcaactacctcggccagttcgaactgaccggtgagctctacacc
ggctcgcccggcgaactgtccttggccgccgaccccggcggcgtccgtccccatctgctc
gacgtggtcggccaggtcaccggcgacacgctggagttcacctggcactacgcggaaggc
gtgcacgaagaggtcaccgtgacccggttggccgaaggcatgctggagaacctgcgtgga
ctcctcgggcactgcgccgaacccggcgcgggcgggcggacgccgtcggacttcccgctg
gcggggctcgatcagtccactgtggacgagctggtcggcgacggccgggacgtggaggac
gtgtacccgctgacgccgatgcaggcgggcatgctgttccacagcctggcccggcccggc
gatcgcaactacttcgaacagatcaccttcatcgtcgacgacgttcccgatccccgtgcg
ctcgtcgcggcctggcaacgggtggtcgagcggaccccgatcctgcggagccggctcgtc
tgggcaggggtaccgcgtccgctgcagatcgtgcggcgttcggcggagatcccggtgagc
tgcccggattggtccacagtggacgcggaggaggcgttgcggcggcggttggccgaagac
ctcgccgaagggctcgacctgacccgtgccccgctgacgcggctggtcgtcgccaaggag
tcggcgacctcggtccgggtcatctggacgttccatcacgtactactggacggctggagc
gtcttcggtgtcctgtccgacgtcctcgccgtgctgcgcggtgaagaaccgccggtgcga
cgcccgttccgcgactacgccggatggctcgccgcgcaggacgacgaagccgccgaagct
cactggcgggccgaactcgccggggtgacgccgacgccgctgcccggcgatcgcggcgcc
cgcgcgcacgccgccagttcgtccgcccgggtgccggtggacttcgacgacaccacgacc
gcccggatcaacgcgttcgcgcgacggcaccacctgacgctcaacacgatcgtccagggc
gcctgggcggcgctgctgtcccgctacagcggcgaatccgaggtgtgtttcggcgcgacg
gtgtcgggaaggccggtcgagctgccgggagcggacgacattgcgggcttgttcatcaac
actctgccggtgcgggtccggctcgacgccggacgcggcctcgtcgactggcttcgggaa
ctgcaagcggcacaggcggaatcgcgccggttcggccatgtcggcctgccgcggttgcag
tcctggagcgacgacggcggcagcctgttcgacagcatcatcgtcttcgagaactacccg
gtgggggacgtcgccggggtgcgggacgtccgcgcggccgaacgcaccaactacccgctc
ggcgtcgtcgcgtatccgggccgccggctgtcgctgatgctgacccacgaccccgagttg
atcggaccggatctggcccggcggctcgccgggcacctcgaaacgctgatccgtggcttc
gtggacacaccgtacgaccccgtgacacgggtaccgatgctgtcggagcgggagatccgg
cacctgctccgcgagcgcagcgccacagtccggcgcataccggaaggatcggtgccggaa
cagttcgaggctcgcgcacgccggaatcccgacggggtcgcactggtgaccgatgaggaa
accgtcacctacggcgaactcgacgtccgggcgaaccgtttggcgaaccggctgcgcgcg
ctcggcgtgcgcgccgaagaccgggtcgcgctcctgatggaccggtcacccgccctcgtc
gtggccgaactcgcgatcctgaaggcaggcggcgcctacctgcccttggacctgcgcgca
cccaccgagcggttgcggttgctgctgagcgaagccgaggcggacgtcctcgtcaccgat
gaggcctggctgtccatcgccgaggagatccacgacggcgcgatcgtcatggacgcgggt
gacgcccccgaagcctcgcccgtggtgccggtcgaccccgagcagctcgcctacgtcatc
tacacctccggctcgaccggcaagccgaagggcgtcgccgcccggcatcgcgacgtcctc
gctctcgcggccgatcagcgtttcgcggcccacgaccgggtgctgctgcattcaccgcag
gccttcgacgcgtccacgtacgagctgtgggtgcccttgctgaacggtggcacggtcgtc
ctggccccgccgggggaactcgacgtccacacgctcggccgggtgatcgccgcgcacgcc
gtgacgggtgtcttcatgacgaccgggctgttccggctcgtcgcgcaggaggccccggag
acgttcgccggcgtgcgggaagtctggacgggcggcgacgccgtccccgccgtcgcgctg
cgccgggtccgggccgcgtgcccgcggaccctggtcgccgacgtctacggccccaccgag
accacgacgttcgccaccgtgcacccgctgccggacgaggtacccgacgtcgtgccgatc
ggggcaccgctggacaacacccgtgcttacgtcctcgacgacggcttgcgcctggtgccg
ccgggtgcgcccggcgagctgcatctcgccggggcagggctcgcgcggggctacctcgga
cggcccgggctgaccgcggaccggttcgtcgcggatccgttcggcccgccgggggagcgg
atgtaccgcaccggcgacgtggtgcgctggaacgacgaggaggcactcgaattcgtcggc
agggtggacgaacaggtcaagatccgcggtttccgcgtcgaaccgagcgagatcgaggcc
gcgttgggtgagcaccccggcgtcgagcaggcagccgtgctggcccgcgcggacggcggg
gtgaaacggctggtcgcctacgtcgtcggcgagaccgaagggctcggggaattcttgggg
cggaccctgccggactacatggtcccggcggcgttcgtccggttggcgaagttcccggtc
aacgtcaacgggaagctcgaccgcaccgccttgcccgccccggacttcggggcccgtgac
cacgtcgcgccgcgtaccgatcgcgaactcgtgctcgccgggatctgggccgaggtgctg
ggtgtcgaacgggtcggcgcgaccgacgacttcttcgaactcggtggcgattcgatcctc
agcatccaggtggtgtcgaaggcccggcgtgccgggctggaactgctgcccggtgacctg
ttcgcccatcggaccccggcggcactcgctgccgcggcacgcagcgccaccgaagccgtc
cgtcgcggcccggtcagcggcgaggtgccgctcaccccgatccagcggtggttcttcgcg
acccagacggccgatccggagcacttccaccagttcgtccggttaggacctgcgcggatc
gaccgagccgcggcgcgcaaggccgtggacgcgttgctggagcaccacgacgcgctgcgg
atgcggttcacccacgaggacggctggaagcaggagaacggtcctgtcggcgccgagaca
ccgctgatccgcctcgacctctccgagcatggcgtcaccctcgctgtgcaccacctcgtc
gtcgacggtgtgtcgtggcgggtgctcgccgaggatttcgaccgcggttacgcccaggct
ctgcggggcgaggcgatcgacctcgggccgcgcaccacctccttccgggagtgggcgatc
aggctcgccgagcacaccgccggcggcggattcgacgacgaactcgaccactggcacggc
ctgccggcggacacctcgatcccggtcgacggcgagggtgaggccacggtcgcctcgatg
cgcgaggtcaccgtgcggcttcccgaagcggagaccgaggcgctgctgcgggaagtgccc
gccgcctatcgcacgcaggtcaacgacgtgctgctcaccgcgctgggccgggtgctgcgg
gactggacgagcaaggtcccggtcatcgacctggaaggacacgggcgcgaagacctgttc
gacgacgtcgacctgtcccgcacggtgggctggttcaccagcgtcttcccggtcgcactc
gacgtccccgaagactggggtacggcactgaagtcggtgaaggagcagctccgggccgtg
ccacgacgcgggatcggctacggcgccctgcgtcacctggcggggaccgcgccgtcgatc
gacccggcggtgagtttcaactacctcggccgcttcacctcgggcaggctggaatcggac
gagagcgagctttcggcgcgagcgcatctgctcgacgtcgtcggccgcgtcgagtccggc
gaactcgaactgacctggtactacaccgagggtgtccaccacgagtccacagtggacagg
ctcgccgaggcgatgctgacggccctgcgggagatcatcgcgcattgcactgaaccggag
gcaggtgggcgcaccccgtccgatttcccgctgctcgcgctcgatcaatccacagtggac
accctcgtcggcgacggcagggcggtcgaagacctctacccgctcacgccgatgcaggtg
gggatggtgttccactcgttgtcacagccggacgagcggctctacttccagcaggtcggt
ttcgtcgtcgaaggtgtcgacgacgtcgacgcgctggccgaggcctggcagcacgtcgtc
gaccgcactcctgtgctgcgcacccggatcgcctgggagggtgtgccggaaccggtgcag
gtggtgcggcgacgggtgaccgtcccggtcaaccggctcgactggcgcgcccactccgcc
gcggggcaggagcggttctggcaggaggtcctggccgcggaccgcgccgaggggctggac
ctggacggtgaaaccctgctgcggctgaccctggcacggctttcggatacggaagtccgg
gtgctgtggacgttccaccacgtcctgctcgacggctggagcgtcttcggggtgctgtcc
gacgtcttcgccgcctactccgggggcgaactaccggagcggccgccgttccgcgattac
gtcgcgtggctggaccgccaggacgacaccgaagcggaacgccactggcgtcgcgaactc
ggcgacttcaccgcacgcggccggctcacggcgcaggaccacacgagcaggtcggccgag
tggctgcgggtcccggtcgaaagctccgcccggctcgcggaagccgcgcggaaggcgggg
ctcacgatgaacaccgtgctgcagggcgcgtgggcgctggtgctgtcccggctgaccggc
gagcgtgacgtctgtttcggcaccaccgtttccggccgcccggtcgatctgaccggcgcc
gacgacatcaccgggatcttcatcaacacgctcccggtccgcgtcaccaccgatcggtcg
ccggtcgcgcgatggctggcggccttgcaggaccgccaagtggagtcccgcaggtacggg
catctgccgttgacgaagttgcaggcgtggagcggttccgacggcagcctcttcgacagc
atcgtcgtcttcgagaactatccgatcgattcggcgacgcgggacgggctgcggttgcgc
gacgtcgatgccgccgagacgacgaactacccgatcagcgtcgtcgcgtcgccgggggaa
cggctgagcctcgacgtcggctacgaccccgatctgttcgacgccgcgacggcagagcgg
atcacggaccagctcgtgggtgtgctcgacgccttcgccgaggacctgaaccgtccgctc
gacagcatcgacctgctcaccgacgccgaacggctccagatcctcggcgactggaacgac
accgcgcatccgctgccggaaggaagtctcgccgagctctttggacggcaggtcgcgcgc
gctcccggcgcggtcgccctcgtcggcgacggcgtgcgcctgacgtacgcggacctggac
gagcgcgcggaccggctcgcccggcggctggtgtcgctcggcgccggtcccgaaaccgtc
gtcggcgtgctcatggaccgttccccggacctggtcgtcgccgaactcgccgtggtcaag
gcgggcgcggcgtatctcccgctcgacacgagggctcccgcgccgcggctgaagacactg
ctggacggtgtgccgatcctcgtcaccgaccggacccgcgccgagtcggtggtccacagt
ggacagatcgtcgtccccgacggccggaccgcggacgtggcgctgcccggcgcggcgccg
gacaacctggcttacgtgatgtacacgtccggttcgacgggcaggccgaagggcgtggcc
gtacgccagcgtgacgtcgtcgccctcgccgccgaccggcgcttcgccgcgcacgagcgg
gtactgttgcacgcttcgcccgccttcgacgcctccacctacgagctgtgggtccccctg
ctcaacggcggcactgtcgtcgtggcccctccgggagacctggacgtggacaccctccgg
cgggtcatcgccgagtacgaggtccacggggcgttcttcaccgccgggttgttccggctg
ctcgcccaggaagccccggagaccttccgcgggatgcgcgaggtctgggcgggcggcgac
gtcgtcccggccgccgcggtccggcgggtgcgggaggcgtgcccgggcacggtcgtcgtc
gacggctacggtccgaccgagacgacgaccttcgccacctcgcatccgattccggacgac
gtcaccggtcccgtcccgatcgggaaaccgctcgacaacatgcggacctacgtcctcgac
gccgagctgcggctcgtgccgcagggcgtgcccggtgagctgtacatcgccggtgccgga
ctcgcccgcgggtacttcggtgatccggcgctgaccgccgaccggttcgtgcccgacccg
ttcggcccgccgggggagcggatgtaccgcaccggcgacctcgtccgctggaacccgctc
ggcgaactggagtacaccgggcgcgccgacgagcaggtcaaggtccgcggtttccggatc
gaaccggcggagatcgaggccgcgctgaccgcgcatccgggcgtcggccaggcctcggtc
ctgaccagggaagaccacggcgtcaaacgcctcgtcgcgtaccacaccggcgacgcggac
ggcctcgccgagttcctcgggcggaccctgcccgactacatggtgccctcggtgttcgtc
cggctcgaccgtttcccgttgaccgccaacgggaaggtcgaccgccgcgccctgcccgcg
cctgacttcggcgagaagtcggccgggaccgcgcccacgaccgaggccgaacgcgcgctc
gccgggatctggtcggacgtgctcggcgtcgcggacgtcggcgccgaggccaacttcttc
gaactgggcggcgactcgatcctcagcatccaggtcgtgtcgcgtgcccgccgcgccggg
ctgaacctgctgccccacgacgtcttccggcatccgaccctcgccgcgctggccgcccac
gccggcggcgacgccgggccgcgcgccgaacaggggccggtcaccgggacggcgccgctc
accccgatccagcactggtacttcgacggcctgccggaccggttcgaccagcgagtggtg
ctggaattcaccgaggacgtcgacgaagcagcgctgcgccgtgcgctggaagccgtgtgg
gcgcaccacgacgggctgcggctgcgcttcggacgcgacggcgtccagcacggcgaaccg
gtgtggccggccgagctgctcaccgacgagatcgccttcgacctcggacgcgggccgttg
ctggccgcggtgctcgacgggcggcggctgaccctggccgcgcaccatctcgtcgtcgac
ggcgtctcctggcggatcctgctggaggacctggaaaccgcctaccgcggcggcgaactc
gggccgaagacgacgtcgtacctggagtgggccaggcggctggccgagcacgcggagtcc
ggcggcttcgacgacgaactggcttactggcgcgagatcccggcgctgcccgacgacggc
gaaccggccacgatcgccgacaccggcgaggtgacggtccggctcaccgccgaggagacc
agggcgctgctccaggaggttcccgaggtctatcgcacgcaggtcaacgacgcgctgctc
gccgcgctgggccgggtgctgcgggactggaccggacagaccccggtgatcgacctggag
ggccacggacgcgaagacctgttcgacgacgtcgacctgtcccgcacggtcggctggttc
accagcatgttccccgtggcgctcgacgtcccggaggactggggcgccgcgctcaaagcg
gtgaaggaacagctccgggcggtgccgcggcggggcatcgggtacggcgccctgcggtat
ctcaccggtaccgcgccggccatcgatccccggatcggcttcaactacctcggccggttc
gaggacgccgaggcgggcgcgttccggaccggcgcgctcgacgccgacgtcgatccggcc
gctcccgcgcgtcacacgctcgatatcgtcggccgtgtcgtggccgggacactggagctg
acctgggcgcacgtggagacccggcacgatcgtggcaccgtcgaagaactcgcggagcgg
atgctggccgcgctgcgtgagatcatcgcgcactgcgcggcaccggaagccggtggccgc
acgccgtcggacttcccgctcgccaccctcgaccagtccacagtggacaaattggtcggc
gacggccgagcggtcgaggatgtcttcccggtgacgcccatgcagggcgggatgctgttc
cacggcctttcccagacggcgcaaggcatgtacgtcgagcaggcgacattcgtcctcgaa
ggcgtcaccgacctcgaccggctcgccacggcgtggcagcgggtcgtggaccgcacgccg
gttctgcggacggcgttcgtgtgggccggcgtcgaggagccgctgcaggtggttcaccgc
gaggtacggctgccgatccgtgtgctggacggaaccggtcacgatctccagcggctcttg
gctgaggaccgcgaacaagggctcgacctcgcggaggcgccgctgatgcgcgtggcgctc
gtgcggttgtcggagaccgaggtccaggtgctgtggacgttccaccacgcactgctcgac
ggctggagcgtcttccacgtcctgtccgacgtctgtggcgcctacgccgggcagacgctg
cccacgaggccgccgttccgggactacctcgcgtggctgggccgcctcgaccggaccgac
gccgaacggttctggcgtcgcacgctttccgggatcgacgggccgacacccgttcccggc
gatcgggcgcccgcggccgggcacatcgcctgttcgtccgagtggttgcccgtgcgcttg
gacgaggcggcgacgagcgggctcgacgagttcgtcaaacgccacggcctcacgcacaac
gtggtcctgcaaggggcctgggccttgctgctgtcggcttacagcggccacgacgacgtc
gtgttcgggtccaccgtttccgggcgcccacccgaggtgaccggggtggacgcgatcacc
ggcatcttcatcaacacgctgccggtcagggtcgggatcgaccgtggtgcccgtgtcgcc
gagtggctcgcggatcttcaggcgagtcaggccgaggcacgccgtcacggacatcttccg
ctcgcgctggtccaaggctgggcggagctgcccgggggagtgaacctctgcgagagcctg
gtggtgttcgagaactatccgatcaccggtgccgaggccgggcacggcctgaccgtgcgc
gatctgtcggcacgagagacgacgaacttcccgctgacggtcgtcgcgtcgcccggtcgt
gagctgaacgtcgacctgggctacgacccggccttgttcgacgccgaaacggtgagccgg
ctggccggtcacctgctcacgctgctccgggaactgacggtggacggcgctcgggcgatc
accgacgtgtcgatgctgaccacggaggacgaactactcctggcgcgatggacggaaacc
ggcacggcggcccccgcccggtcgctgccggacctcttcgccgagcaggtccgcgcccgg
cccgacgcggtggctgccgtcctcgacggcgaatcggtcacgtacgccgagctgaaccgg
cgggcgaaccggctggccaaccgcctgatcgggctcggcctgcgacccgaggaaccggtc
ggcctcgccacgagcagggcgggcaccgtcgtggcggaactggccgtggtcaaggcgggt
ggcgcgtatctgccgatcgacacccgcgccccggcggaacgacggcaggtactgctcgaa
ggtgtgcggttcgtcgtgtccgacacggagtatccggacgccatccggctgtcctcagtg
gacgacgagccggacggtgatcccgccgtcgtcgtcgatcccgaccagctggcgtacgtc
atgtacacctcggggtccaccggcacgccgaagggcgtcgccgtgcggcaccgtgacgtc
gcggccttggccgtggacagccggttccgcggcggggcacacgaacgcgtgctgctgcat
tccccggcggccttcgacgcgaccacctacgaactgtgggtaccgctgctcaccggcggc
cgcgtcgtcacggccccggacggcggcctcgacgcgcaccggctgcggaccttgatccgc
gagcacgggctgaccgggatgtgggtcacggcgggcctgttccgcgtgctggcgcaggaa
agcccggactgcttcgccgggctgcgggaggtgtggaccggcggcgacgtcgtgcccgcc
gaggcggtgcggcgagtgctgggtgcctgtcaggggctgcgcgtcgtggacggctacggc
cctaccgagacgacgacgttcgccaccgcccatccgatggacgagacggttccggaccgg
gtcccgatcggcaccccgctggacgggatggtcgcccgcgtgctggatccggagctgcgc
ccggtgccgccgggaatgccgggcgagctgtacctcgccggcgcgggtctcgctcgcggc
taccgcgagcggccggggctgaccgccgaccggttcctcgcggccccgggcgggcaacgg
atgtaccgcaccggcgacgtcgtccgccggacccgagcgggcaccctcgaattcctcggg
cgggcggacgatcaggtgaagctgcgcgggttccgggtcgagccgggtgaggtcgaggca
gtgctggcccggcatcccgccgtggcgcaggcggccgtcgtcgttcgcgaggaccagccc
ggtgccaagcaactcgtcgcctacgtcgtgtcggaagccgggcaggacacactccgggac
ttcctggccgatcggctgccggactatctggtgccgtcggcgttcgtcgcgctggaccgg
atcccggtcagcgccaacggaaagctcgaccgcaaggcattgcccgcgcccgccgcgccg
gagacggggtacgtcgagccggaaaccgaaaccgaacaggcgctggccgcgatctgggcc
gaagtactcggcgtggagcgggtcggcgccgaggacaacttcttcgccctcggcggggat
tcgctgcggagcctgcacatcgcggccaaggcgggcgccttgttcgccgtccggctgacc
ccggccgacatcctgaccgcgcgcaccgtcgcgggactggccgggacggtcgaagaactc
attttgggcgagctcgagagcctcgcctccgaaacggaagcgtga
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