Amycolatopsis orientalis: SD37_00815
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Entry
SD37_00815 CDS
T06703
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
aori
Amycolatopsis orientalis
Pathway
aori00280
Valine, leucine and isoleucine degradation
aori00640
Propanoate metabolism
aori00785
Lipoic acid metabolism
aori01100
Metabolic pathways
aori01110
Biosynthesis of secondary metabolites
aori01210
2-Oxocarboxylic acid metabolism
Module
aori_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
aori00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
SD37_00815
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
SD37_00815
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
SD37_00815
Enzymes [BR:
aori01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
SD37_00815
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Motif
Pfam:
E1_dh
TPP_enzyme_C
Motif
Other DBs
NCBI-ProteinID:
ANN14337
UniProt:
A0A193BQ71
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Position
complement(178989..180194)
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AA seq
401 aa
AA seq
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MPSEHWTHPEPGDGPAAVAAQPSPEQVIAGLRATSEGGAELTQLLTPEGERVSSPRFDRY
VDDIDAEALKSLYRDMVLVRRADREANAMQRQGQLGIWVPLLGQEAAQIGSGRALQKRDM
AFPSYREHGVAYARGVDLKEVLGIFRCTDHSGWDYKAHGFHPYTIVIGNQVLNAAGYAMG
QKFEGKVGDDNGEATICYFGDGATSQGDVHEGFVWAAVYDAPLVFFCQNNQWAISEPTER
QSRLPLYQRARGYGFPGIRVDGNDVLACLAVSRWALEECRHGNGPVLIEAFTYRMDAHTT
TDDPTRYRLSDELEEWKLKDPIERVRAYLARGGGADQAFFDQVQADSDAFAAELREYCFN
MPEPPPERIFKNVYAESTPMLDAQREQYLSYLDGFVGAGEH
NT seq
1206 nt
NT seq
+upstream
nt +downstream
nt
atgccgtccgaacactggacgcacccggagcctggagacggccccgccgcggtagcggcc
caaccgtcccccgaacaggtgatcgccggtttgcgagcaacgagcgaaggtggcgctgag
ctgactcagctgctcacccccgaaggcgaacgggtctcctcgccgcgattcgaccggtac
gtcgacgacatcgacgcggaagccctcaagagcctctaccgcgacatggtcctggtccgc
cgcgcggaccgcgaggccaacgcgatgcagcgccagggccagctcggcatctgggtcccg
ctgctcggccaggaggccgcgcagatcggctccggccgtgcgctgcagaaacgggacatg
gcgttccccagctaccgcgagcacggtgtcgcgtacgcccgcggcgtcgacctcaaagag
gtgctcggcatcttccgctgcaccgaccacagcggctgggactacaaggcccacggcttc
cacccctacaccatcgtgatcggcaaccaggtgctcaacgccgccggttacgcgatgggc
cagaagttcgaaggcaaggtcggcgacgacaacggcgaagccaccatctgctacttcggt
gacggggcgacttcgcagggcgacgtgcacgaaggcttcgtctgggccgccgtctacgac
gcgccgctcgtgttcttctgccagaacaaccagtgggcgatctcggagcccaccgaacgc
cagtcgcggctgccgctctaccagcgcgcccgcggttacggcttccccggcatccgcgtg
gacggcaacgacgtcctcgcctgcctcgcggtctcccgctgggcgctggaggaatgccgt
cacggcaacggcccggtgctgatcgaggcgttcacctaccggatggacgcgcacaccacc
accgacgaccccacccgctaccggctctccgacgagctggaggagtggaagctgaaggac
ccgatcgagcgcgtccgggcgtacctcgcccgcggtggcggcgccgaccaggcgttcttc
gaccaggtgcaggccgattcggacgcgttcgcggccgagctgcgcgagtactgcttcaac
atgcccgaaccgccacccgagcggatcttcaagaacgtctacgccgagtccacgccgatg
ctggacgcgcagcgcgaacagtatctgtcctatttggacggtttcgtcggggcgggtgag
cactga
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