Amycolatopsis orientalis: SD37_12215
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Entry
SD37_12215 CDS
T06703
Symbol
thyX
Name
(GenBank) FAD-dependent thymidylate synthase
KO
K03465
thymidylate synthase (FAD) [EC:
2.1.1.148
]
Organism
aori
Amycolatopsis orientalis
Pathway
aori00240
Pyrimidine metabolism
aori00670
One carbon pool by folate
aori01100
Metabolic pathways
aori01232
Nucleotide metabolism
Module
aori_M00938
Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:
aori00001
]
09100 Metabolism
09104 Nucleotide metabolism
00240 Pyrimidine metabolism
SD37_12215 (thyX)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
SD37_12215 (thyX)
Enzymes [BR:
aori01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.148 thymidylate synthase (FAD)
SD37_12215 (thyX)
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Motif
Pfam:
Thy1
CHASE3
DUF2719
Motif
Other DBs
NCBI-ProteinID:
ANN16336
UniProt:
A0A193BVS6
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All DBs
Position
2760183..2760935
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AA seq
250 aa
AA seq
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MAETVSPKVQLIAKTEFFPPSDVPWSTDADGGEALAEFAGRACYQSWKKPNPKTATNAGY
LEHIIDVGHLSVLEHGSVSFYITGISRSLTHELIRHRHFSYSQLSQRYVPERDAAFVEPD
VIAQDPELHAKFLAASQAAVDAYTELLAGLEEKFADVPSATLRRKQARQAARAVLPNATE
TRIVVTGNYRAWRHFIAMRATEHADVEIRALAIECLRELQKASGNVFADFTISALPDGTE
IASSPKVLEG
NT seq
753 nt
NT seq
+upstream
nt +downstream
nt
gtggccgagaccgtgtcacccaaggttcagctgatcgcgaagacggagttcttcccgccg
tcggacgtaccgtggtcgaccgatgccgacggtggtgaggcgctggccgaattcgcgggc
cgggcctgctaccagtcctggaagaagccgaacccgaagacggccaccaacgccggctac
ctcgagcacatcatcgacgtgggccacctttcggtgctggagcacggctccgtcagcttc
tacatcaccgggatctcccggtcgctgacgcacgagctgatccgtcaccggcacttctcc
tactcgcagctctcgcagcgctacgtccccgagcgggacgccgcgttcgtcgagcccgac
gtcatcgcgcaggacccggagctgcacgcgaagttcctcgccgcctcgcaggccgccgtg
gacgcctacaccgagctgctcgccgggctggaggagaagttcgccgacgtgccgagcgcg
accctgcgccgcaagcaggcccgccaggccgcccgcgccgtgctgccgaacgcgaccgag
acccgcatcgtggtcaccggcaactaccgcgcctggcggcacttcatcgcgatgcgcgcc
accgagcacgccgacgtcgagatccgcgccctggccatcgagtgcctgcgcgagctgcag
aaggcctcgggcaacgtgttcgcggacttcaccatctccgcgctgcctgacggcaccgag
atcgcgtcgagcccgaaggtcctcgaaggctga
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