Amycolatopsis orientalis: SD37_31220
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Entry
SD37_31220 CDS
T06703
Name
(GenBank) dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
aori
Amycolatopsis orientalis
Pathway
aori00790
Folate biosynthesis
aori01100
Metabolic pathways
aori01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
aori00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
SD37_31220
Enzymes [BR:
aori01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
SD37_31220
6.3.2.17 tetrahydrofolate synthase
SD37_31220
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GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
ANN19650
UniProt:
A0A193C5N3
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Position
complement(7187060..7188736)
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AA seq
558 aa
AA seq
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MPRGDGRDSEEFAESPDLADLDSFAGVDELGARAHDPSDDTDPDLDAPDAAYQAGGGAGG
GIGGIGQLGDNLALGPVPDLVAPEDVELHELDDQGDDVAPADPNGQQARRELLAVEAELN
LRWPETKIEPSLTRIAALVNLMGEPHRGYPVLHVAGTNGKGSTTRMIDALLTRMGLRVGR
YTSPHLQLVTERIALDGAPISAAAYVDLYRDVAPYVTMVDNAGGADAVPMSKFEVLTGMA
FAAFADAPVEAAVVETGLGGSWDATNVVDGEVAVITPIGVDHVEYFGGDPAKAAVEKAGI
IKPGSVAVIAEQEPEVQKILLERAVEVDASVARAGSEFGVLEREIAVGGQMLKLQGLGGV
YDEIFLPLHGAHQAANAALALAAVEAFFGAGKDRQLVVEAVREAFAEVETPGRLERVRAA
PTVLLDAAHNPHGAKALATTVAEEFAFRRLVAVVGVMADKDARGILDALEPVVSEIVVTK
NSSPRAMPLDELNDIAISIFGEDRVVAEASLDSAIETAIGLVEQSDDPEEPLAGGGVLVT
GSVVTAGEARTLFGKEPA
NT seq
1677 nt
NT seq
+upstream
nt +downstream
nt
gtgccgcgaggtgacggccgggattccgaagaattcgcagaatccccggacctggcagat
ctggacagtttcgccggtgtggacgaattgggggcacgtgcccacgatccgtccgacgac
accgacccggatctggacgcacccgacgccgcgtaccaggcgggcggcggggcgggtggc
ggcatcggcgggatcgggcagctgggggacaacctcgcgctcggcccggtgccggacctc
gtcgcgccggaggacgtggagctgcacgaactggacgaccagggtgacgacgtcgccccg
gccgacccgaacgggcagcaggcacgccgcgagctgctcgcggtcgaggccgagctgaac
ctgcgctggccggagacgaagatcgagccgtccctcacccggatcgcggcgctggtcaac
ctcatgggcgagccgcaccgcggctatccggtgctgcacgtcgccgggaccaacggcaag
ggctcgaccacccggatgatcgacgcgctgctgacccgcatgggcctgcgcgtcggccgg
tacacgagcccccacctgcagctggtcaccgagcggatcgccctcgacggcgccccgatc
tccgccgccgcgtacgtcgatctgtaccgcgacgtcgcgccgtacgtgaccatggtggac
aacgcgggcggcgccgacgcggtgccgatgagcaagttcgaggtgctcaccggcatggcg
ttcgcggccttcgccgacgcgcccgtcgaggccgcggtcgtcgaaaccggcctcggcggc
tcgtgggacgccaccaacgtcgtggacggcgaagtcgccgtcatcacgccgatcggtgtc
gaccacgtcgagtacttcggcggcgatccggccaaggccgcggtggagaaggccgggatc
atcaaacccggcagcgtcgcggtcatcgccgaacaagagcccgaagtgcagaagatcctg
ctggaacgcgccgtcgaggtcgacgcgagcgtcgcccgcgcgggcagcgagttcggggtg
ctggagcgcgaaatcgccgtcggcgggcagatgctgaaactgcagggcctcggcggggtg
tacgacgagatcttcctgccgttgcacggcgcgcaccaggccgccaacgccgcgctcgcg
ctggcggccgtcgaagcgttcttcggcgcgggcaaggacaggcaactggtcgtcgaagcc
gtccgcgaggccttcgccgaggtcgagacccccggcaggctggagcgcgtccgcgccgca
ccgaccgtgctgctcgacgccgcccacaacccgcacggcgccaaggcgctcgccaccacc
gtcgccgaggagttcgcgttccgccgcctcgtcgccgtggtcggcgtgatggccgacaag
gacgcccgcggcatcctggacgccctcgaaccggtcgtttccgagatcgtcgtcaccaag
aactcgtcgccgcgcgcgatgccgctcgacgaactcaacgacatcgccatctcgatcttc
ggcgaagaccgtgtcgtcgccgaagcgagcctcgactccgcgatcgaaacggccatcggc
ctcgtcgagcagagtgacgaccccgaggagccgctggcgggcgggggcgtgctggtcacc
ggttcggtcgtcacggcgggcgaggcgaggaccctgttcggtaaggagccggcgtga
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