Actinomyces oris: AXE84_09135
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Entry
AXE84_09135 CDS
T04280
Name
(GenBank) tetrahydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
aos
Actinomyces oris
Pathway
aos00790
Folate biosynthesis
aos01100
Metabolic pathways
aos01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
aos00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
AXE84_09135
Enzymes [BR:
aos01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
AXE84_09135
6.3.2.17 tetrahydrofolate synthase
AXE84_09135
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
DUF6158
Motif
Other DBs
NCBI-ProteinID:
AMD99559
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Position
2280642..2282450
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AA seq
602 aa
AA seq
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MPVDDDSKQVRPGAAFGIPEGATGEEVVDAVFGQAGIDPELLPYLEAAGAPDLAEGEGLT
VSVSELQEAGAQRQADAEVQDREDLEALRELVAANMIPGGDTDRLEELLAEVEADDSDDW
DSWEPQLADDSEGEHLRDLQAAARGVEVAARMREVEAEILARAPEHQVQPSLERVEAVLD
LLGNPERTYRTVHITGTNGKTSTARMTERLLAAGGMRTGRFTSPHLATIRERISLDGEPI
SEEGFIAAWEDVAPYVAMVDERSQTAGGPRLSFFEVLAVMALAAFADYPVDVAVIEVGLG
GRWDATNVIGSDVAVITPIGRDHERWLGSSITEIAHEKAGIIKDGSTVIVAHQVSEAAAE
IEQAVASHRVVVRRERDPHEDPASPEAGVLQVLDRQLAVGGQLVTFATAAAVYEDAFVPL
HGEYQAHNALLALAAAEAVHGGRRLPARIVEDGFASVTSPGRLEVLRSSPTVLVDAGHNP
HGIEALAGAVEEAFGFQHLVAVLGVMADKDAEGILAGLEPVTDAVVCVPIDSPRAMDVED
LGEIAREVYGADRVVVSQQLGEGVERAVALSEGYDAPLTASGILIVGSVVLAAEARALFG
RP
NT seq
1809 nt
NT seq
+upstream
nt +downstream
nt
gtgcccgtagacgacgactccaagcaggtcaggcccggcgccgccttcggcatccccgaa
ggggccacgggggaggaggtcgtcgacgccgtcttcggccaggccggcatcgaccccgag
ctcctgccctacctggaggccgcaggcgcccccgacctggccgagggtgaggggctgacc
gtctccgtttccgagcttcaggaggccggtgctcagcggcaggccgacgccgaggtccag
gaccgtgaggacctcgaggctctgcgcgagctcgttgccgccaatatgatcccgggtggt
gacaccgatcgcctcgaggagctcctggctgaggtggaggccgacgactccgacgactgg
gactcctgggagccccagctcgccgacgactccgagggtgagcacctgcgcgacctgcag
gctgccgcccgcggcgtcgaggtcgccgcccgcatgcgcgaggtcgaggccgagattctc
gcacgcgctcccgagcaccaggtccagccctccctggaacgagtcgaggccgtcctcgac
ctcctgggcaaccccgagcgcacctaccgcaccgtccacatcaccggcaccaacggcaag
acctccaccgcccgtatgaccgagcgactgctggccgccggcggcatgcgcaccggccgc
ttcacctccccgcacctggccaccatccgcgagcgcatcagcctcgacggtgaaccgatc
agtgaggagggcttcattgccgcctgggaggacgtggccccatatgtcgccatggtcgac
gagcgctcccagaccgcaggcgggccccgcctgtccttcttcgaggtcctggccgtcatg
gctctggccgccttcgccgactaccccgtcgacgtcgccgtcatcgaggtgggcctgggc
gggcggtgggacgccacgaacgtcatcggctccgacgtcgccgtcatcaccccgatcggg
cgcgaccacgagcgttggctgggctcgtcgatcaccgagatcgcccatgagaaggccggc
attatcaaggacggttccaccgtcatcgtcgcccatcaggtctccgaggccgctgccgag
atcgagcaggccgtggcctctcaccgggtcgtcgtgcgtcgggagcgggaccctcatgag
gaccccgcctcgccggaggccggcgtcctgcaggtcctcgaccgccagctcgccgtcggc
ggtcagctggtcaccttcgccacggcggcggccgtctacgaggacgccttcgtcccgctg
cacggggagtaccaggcccacaatgccctgctggccctggccgccgccgaggcggtccac
ggtgggcgccggctgccggcgcgcatcgtcgaggacggtttcgcctccgtcaccagcccg
ggccgtctggaggtgctgcgctcctcgccgacggtcctcgtcgacgccgggcacaacccg
cacggcatcgaggccctcgccggagccgtcgaggaggccttcggcttccagcacctcgtc
gcggtcctgggtgtcatggccgataaggacgccgagggcatcctggcgggcctggaaccg
gtgaccgacgccgtcgtgtgcgtccccatcgactcaccccgggccatggacgtcgaggac
ctcggcgagatcgcccgggaggtctacggcgccgaccgcgtcgtggtgagccagcagctc
ggcgagggagtggagcgggcggtcgccctgtcggaggggtatgacgccccgctgaccgcc
tcaggaatcctcatcgtcggctccgtcgttttggccgccgaggcccgcgccctgttcggc
agaccctga
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