KEGG   Actinobacillus pleuropneumoniae AP76 (serotype 7): APP7_1661
Entry
APP7_1661         CDS       T00717                                 
Symbol
mrdA
Name
(GenBank) penicillin-binding protein 2
  KO
K05515  penicillin-binding protein 2 [EC:3.4.16.4]
Organism
apa  Actinobacillus pleuropneumoniae AP76 (serotype 7)
Pathway
apa00550  Peptidoglycan biosynthesis
apa01100  Metabolic pathways
apa01501  beta-Lactam resistance
Brite
KEGG Orthology (KO) [BR:apa00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    APP7_1661 (mrdA)
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01501 beta-Lactam resistance
    APP7_1661 (mrdA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01011 Peptidoglycan biosynthesis and degradation proteins [BR:apa01011]
    APP7_1661 (mrdA)
Enzymes [BR:apa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.16  Serine-type carboxypeptidases
    3.4.16.4  serine-type D-Ala-D-Ala carboxypeptidase
     APP7_1661 (mrdA)
Peptidoglycan biosynthesis and degradation proteins [BR:apa01011]
 Peptidoglycan biosynthesis and degradation
  DD-Transpeptidase (Class B PBP)
   APP7_1661 (mrdA)
SSDB
Motif
Pfam: Transpeptidase PBP_dimer PBP_dimer_2 SURF1
Other DBs
NCBI-ProteinID: ACE62313
UniProt: B3H2J6
LinkDB
Position
complement(1852676..1854637)
AA seq 653 aa
MFGKLGKLTNPKPREKVRDGQAESNLFARRALVAFLGVLVLTGVLLTNLYHLQVVNYDDY
QTRSNGNRIKLLPVPPTRGLIYDRNGKVLAENITYFGLYIIPEKTENLEETLVELRDVVG
LTDEDVEAFRKEKKRTSRYTPILLKGNLNEEQMARFAVNQYRFPSLDVQAYYKRNYPYGE
TLTHILGYVAKINERDKKKLEEEGKFGNYAGSHDMGKLGIEKYYEDQLHGQTGFEEVEIN
NRGKVIRKLRDQPGVAGSSIRLTIDVELQQYIQNLLGDQKGSVVVLDPRDSSVLAMVTNP
SYDNNLFVGGVSGADYKRLLENPARPLYSRATQGTYPPASTVKPFYAVMGLAEGKITPQN
AIYDPGFWILPGTTQRYRDWKKGGHGSTNVNKAITESSDTFFYQLAYDTGIDKMSEWMRK
FGFGQKTGIDIFEESAGVYPNREWKQRRHKKPWVQGDTIPVGIGQGYWIATPLQVAKAQA
ILINNGRVNTPHLMMEVIGSDKTEPYKDPLLYEDIQDVPERFWQVAKFGMYNVINAANGT
GRKAGGSFYRAAGKSGTAQVFNLNGGKYNKNALKKELHDHAWFISYAPYEEPKVSVAIIL
ENAGGGGSNAAPVARQVMDFALRKTLKEPMGTSEPLQNIEQIQPLEEGQANNE
NT seq 1962 nt   +upstreamnt  +downstreamnt
atgtttggtaaactcggaaaattaaccaatccaaaacctcgtgaaaaagtgcgggacgga
caagcggagagcaatctgtttgcccgtcgtgcactggtcgcatttcttggagtattggtg
cttacgggcgtgttattaaccaacctgtatcatttacaagtggtaaattatgacgactac
caaacgcgttccaacgggaaccgtatcaaactattacctgttccgccgactcgcggcttg
atctacgaccgcaacggtaaagtattagccgaaaacattacctatttcgggctttatatc
attcctgaaaaaaccgaaaacctagaagaaacgttagttgaattgcgtgatgtggtcggg
ctgaccgacgaagatgtggaagcgttccgcaaagagaagaaacgtacttctcgctatacg
ccgattttgttaaaaggcaatttaaacgaggaacaaatggcgcgttttgcggtaaatcaa
tatcgtttcccgagtttagacgtacaggcgtattacaaacgtaattatccttacggcgaa
accttgacccatattctcggttatgtggcgaaaatcaacgaaagagataagaaaaagctc
gaagaagagggtaagttcggtaattatgccggctcgcacgatatgggtaaattgggcatt
gagaaatattatgaagaccaattacacggacagaccggctttgaagaagtggaaatcaat
aaccgaggcaaagtgattcgcaaattgcgtgatcaaccgggtgtagcgggcagtagtatt
cgtttaaccattgatgtggaattgcagcaatatattcagaatttactcggtgatcaaaaa
ggttcggtggtggtgcttgacccgcgtgacagcagcgtattggcgatggttaccaacccg
agctacgacaataatttatttgtcggcggcgtatcgggagcggattataaacgcttattg
gaaaatccggctcgtccgttatatagtcgagcgacacagggaacttatccgccggcttcg
acagtgaaaccgttttatgcggtaatgggattggcggaaggcaaaattacgccgcaaaat
gcgatttatgacccgggtttttggattttaccggggacgacacaacgttaccgagattgg
aaaaaaggcggtcacggttcgactaatgtgaataaagcgattaccgagtcttccgatacg
ttcttctatcagctcgcttatgataccggtatcgataaaatgtcggagtggatgcgtaaa
ttcggcttcggacagaaaacggggattgatatttttgaagaatccgccggtgtatatccg
aatcgtgagtggaaacaacgccgtcataaaaaaccgtgggtacaaggtgatacgattccg
gtagggatcggtcaaggttactggattgcaacaccgttacaagtggcaaaagcacaagcg
atcttaattaataacggtcgtgtaaacactccgcatttgatgatggaagtcatcggcagt
gataaaaccgagccttacaaagatccgctgttatatgaagatattcaagacgtgcccgag
cgtttttggcaagtggcgaaattcggaatgtacaacgtaattaatgcggcaaacggtacg
gggcgcaaagccggcggttcgttttatcgagcggcgggtaaaagcggtacggcgcaggtg
tttaacttaaacggcggtaagtacaataaaaatgcgctgaaaaaagagctgcacgaccat
gcgtggtttatcagttatgcgccgtatgaagagccgaaagtttcggtagcgattatttta
gaaaatgcgggcggcggcggctctaatgcagcgccggtggctcgccaagtgatggatttt
gcgttaagaaaaaccttaaaagaaccgatgggaacatcagaaccgttgcaaaatatcgag
caaattcaaccgcttgaagagggacaggcaaataatgagtag

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