Acyrthosiphon pisum (pea aphid): 100167965 Help Entry 100167965         CDS       T01076                                  Name (RefSeq) ryanodine receptor   KO K04962   ryanodine receptor 2 Organism api  Acyrthosiphon pisum (pea aphid) Brite KEGG Orthology (KO) [BR:api00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:api04040]     100167965    04990 Domain-containing proteins not elsewhere classified [BR:api04990]     100167965 Ion channels [BR:api04040]  Voltage-gated cation channels   Ryanodine receptor    100167965 Domain-containing proteins not elsewhere classified [BR:api04990]  EF-hand domain-containing proteins   Other EF-hand domain-containing proteins    100167965 SSDB OrthologParalogGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR SPRY Ins145_P3_rec MIR RR_TM4-6 RIH_assoc Ion_trans EF-hand_7 DUF6096 Motif Other DBs NCBI-GeneID:  100167965 NCBI-ProteinID:  XP_016661950 UniProt:  A0A8R2H7N0 LinkDB All DBs Position X Genome browser AA seq 5101 aa AA seqDB search MADSEGSSEQDDVSFLRTEDMVCLSCTATGERVCLAAEGFGNRHCYLENIADKNIPPDLS QCVFVIEQALSVRALQELVTAASSQEGKGGTGSGHRTLLYGNAILLRHQNSDMYLACLST SSSNDKLSFDVGLQEHSQGEACWWTVHPASKQRSEGEKVRVGDDLILVSVATERYLHTAK ENELSVVNASFHVTHWSVQPYGTGISRMKYVGYVFGGDVLRFFHGGDECLTIPSSWSDVS GQNIVIYEGGSVMSQARSLWRLELARTKWAGGFINWYHPMRIRHLTTGRYLGVNENNELH LVCREEATTASSTFFLRQEKDDQKIILEDKDLEVIGAPIIKYGDSTVLVQHSDTGLWLTY KSYETKKKGVGKVEEKQAVLHEEGKMDDGLDFSRSQEEESRTARVIRKCSSLFTQFISGL ENLQSNRRSSLFCSFVNLNEMVMCLEDLINYFAQPEEDMEHEEKQNRFRALRNRQDLFQE EGILNLILEAIDKVNIITSQGFMVSLAGDESGQSWDVISGYLYQLLAAIIKGNHTNCAQF ANTNRLNWLFSRLGSQASSEGTGMLDVLHCVLIDSPEALNMMKDEHIKVIISLLEKHGRD PKVLDVLCSLCVGNGVAVRSSQNNICDFLLPGKNLLLQTLLVDHVASVRPNIFVGHVSGS AVYRKWYYEVAIDHVEQTTHLNPHIRIGWANTAGYVPYPGGGEKWGGNGVGDDLYSFGFD GSYLWTGGRKSEVMPGTQISNIKKSDVIGCALDLTIPIITFTLNGQLVQGAFRDFNLDGM FFPVISCSSKVSCRFLLGGDHGRLKFTPPDEFSPLFETLLPQQILTIDPCFYFGNLNKCV LTGPWYVEDDTAFVPNPVDTSMVTLPSYIENIKDKLAENIHEMWAMNKIEAGWQYGDKRN DTRKFHPCLIQFDKLPPAEKRYDSQLAVQTLKTVIALGYHISIDNPPSRIKTVRLPNEPF MQSNGYKPAPLDLSAIILSGKMEELIDQLAENTHNLWAKERIQQGWTYGLNEELQMLRSP HLVPYSKVDDAIKKANRDTASETVRTLLVYGYNLDPPTGETNEATLLTDDNTNRYLTFRT YRAEKTYAVSSGKWYFEFEILTSGPMRVGWARFTCSPGYQIGSDENSWAFDGYNEEKIYM GTAESFGRQWQVGDVVGVFLDLMDHTISFSMNGELLMDTLGGETTFSEVQGEGFVPAFTL GLGQKAKLTFGQDVNSLKYFTTCGLQEGYEPFCVNMKRPVTYWYTKDQPIFENTDDFSSV IDVTRIPAGSDTPPCLKISHNTFETMEKANWEFLRLSLPVICLPSFIDEQEKQRRWQEIR IRQHRLLSQSEHATPAHIEQIMKSGFSMSDIKGLHRGYSDDPVENDEMMPNATPLPPRGK NQPPPPRPPRKGSLSRHDDLTIENEGKLNRSSSELNFNIYNHQNGDGQDINKDDKKKRGR SPFRFFSRKKEGPSDNPKRAKTPDPVRNVDRSRNAAHRPNTLNERVTPQIRVSQMDLKLV PPAIPDRPGGPKAMSFTPTSAGIEFVGNEIFDLECLKLINEYYYGVRIFPGQDPTHVYVG WVTTQYHLHTKDFSQNHVRKSTVTIVDEHNRILESIDRQSCYMVRSDELYNEVTNDSSGK GASQGMAIGCFIDIATGMMSFTCEGKETSFKFKMEPDIKLFPAIFVEASSKEILQIELGR TSTTLPLSAAVLQNSERHVLPQFPPRLKVQCLRPHQWARVPNDSLHIHTLKLSDIRGWSI LCEDPVSMIALHIPEEDRCIDILELIEMEKLLSFHAHTLTLYAAVCYQANYRAAHILCTH VNQKQLLYAICSEYMSGPLRQGFYDLLIALHLESHATTMEVCKNEYIIPLGHELTTLYDD PQMGHSLRSLQTESVRPQMKMTEISDVIDNVRNLYSPYFPLQVVREYVMAALEEAVLVNQ VHNRDPIGGSNENLFLPLLKLVDRLLLVGMLRDEDVEKLLIMINPETWDPEFQKDGPDEH RKGLLHMKMAEGAKLQMCYLLHHLCDIQLRHRVESIISFSYQFVNDIQIDQLRRYNEIKQ SDLPSAVAAKKTREFRCPPREQMNAILGFKNLDSDDKENCLIGDDLRERMNEFNEKLMKQ ISLVALQESEDDKSDLNNLNNEGKIKQFYNFINAVKDEGNEDGLNEQEKKIPEEIFRKVL ISTIVSWAEETQIETPKLVREMFSLLVRQYDSVGELIRALEKTYVINFKTKEDVAQMWVG LSQIRSLLPVQMSQEEEELMRERLWKLVNNHTFFQHPDLIRVLRMHENVMAVMMNTLGRR AQAQSQPGGTPVTGQDGEIVPKEKDTSHEMVVACCRFLCYFCRTSRQNQKAMFDHFSFLL ENSNILLSRPSLRGSTPLDVAYSSLMENTELALALREHYLEKIAIYLSRCGLQSNSELIE KGYPDLGWDPVEGERYLDFLRFCVWVNGESVEENANLVIRLLIRRPECLGPALRGEGEGL LRAIIDANKMSERITERRKFLEESGNQENIQLDHPLPESDEDEDYIDTGAAILNFYCTLV DLLGRCAPDSSVISLGKNESLRARAILRSLVPLEDLHGVLSLRFTLQNPAAGQDRPKSDM PSGLIPGHKQSVVLFLERVYGIEMQELFFTLLEEAFLPDLRTATMLDRNDGLESDMALAM NRYIGNSVLPLLIGHSKFYSESDNYANLLDATLHTVYRLSKNRMLTKGQREAVSDFLVAL TSQMQPSMLLKLLRKLTVDVSNLSEYTTVALRLLTLHYDRCAKYYGSTGGQGIYGASSDE EKRLTMMLFSNIFDSLSKMDYDPELFGKALPCLSAIGCALPPDYSLSKNHDDEWYGSKQN IQGPSDGPYNPQPINTNSIVLDNDLNSIVHKFSEHYHDAWANRKLENGWVYGEQFNDVNK SHPRLKPYMMLSEYEKELYKEPVRESLKALLAIGWSIEHSENDAPLNNRGSVRRQSKSNE NVTPFDYHPNPIDMTNLTLTREMQNMAERLAENSHDIWAKKKKEEVMLCGGGIHNQLVPY DLLTDKEKKKDRERSQEFLKYLQYQGYKLHRPNRNGGPSEAEQLAAASTGELRFSYSLLE KLIHYIDRASINMKLLKPSGTFSRRSSFKICTRDIKFFSKVVLPLVEKYFSTHRNYFITV ATASSVLGAASLKEKEMVASLFCKLANLLRSKLMAFGADVRITVRCLQVLVKAIDAKSLV KNCPEFIRTSMLTFFHNIADDLEHTIQNLHDSRYCYLRGTHLKTSTSLFYVNDVILPVLS SLFDHLAAYEYGNELLLNEIQVAAYKMLSSLYTLGTDTSLTHDRKYLKVQLERHRPAFGS CLGAFSSTFPVAFLEPHLNKHNQYSLLNRFADSSLEAQDIMSRMEGTMPTLETVLNEVDQ FIESEKTYADAPHIIDVILPLLCSYLPYWWAQGPDNVALTTGNHVTMVTSEHMNCLLKNV LKLIKKNIGNDNAPWMTQIAAYTQQIIINSSEELLKDPFLPLAERVKKRTETLYHKEESL RGFIKSSTDDTSQIEAQIQEDWQLVVRDIYAFYPLLIKYVDLQRNHWLRNNISNAEDLYN HVSEIFNIWSKSQYFLREEQNFISANEIDNMILIMPTATRRSAVISETSLGGSTGKKKKK HRDKKRDKEKEIQASLMVACLKRLLPVGLNLFAGREQELVQHCKDRFLKRMPDYDVIQFV KIQLTLPDKLDPADEMSWQHYLYSKLGSKKGTTEIKPQQVDEVADRIVAMAKVLYGLHMI DHPQLQSKAIYRSVVSTQRKRAVIACFRQLSLHALTRHRAVNIFVRSFYELWLQDENIGQ EVMIEDLTQSFEEAELKKRDKEEEEGMADPLNQMVTTFCRGAMTERSGALQEDPLYMSYA DILAKSCGEEEEEGNNEEEGSTGNGEEEGGASIHEQEMEKQKLLFHQARLANRGVAEMVL LHISACKGIPSEMVMKTLQLGIAVLRGGNLEIQMGMLNHLKEKKDVGFFTSVAGLMNSCS VLDLDAFERNTKAEGLGVGSEGAAGEKNMHDAEFTCTLFRFIQLTCEGHNLEWQNYLRTQ AGNTTTVNVVICTVDYLLRLQESIMDFYWHYSSKELIDPAGKANFFKAIGVASQVFNTLS EVIQGPCTQNQQALAHSRLWDAVGGFLFLFSHMQDKLSKHSSQVDLLKELLNLQKDMITM MLSMLEGNVVNGTIGKQMVDTLVESASNVELILKYFDMFLKLKDLTSSASFTEIDPNNDG WVHPKDFKEKMEQQKSYTAEEIEFMLQCCESNHDGKIDYIGFTDQFHEPSKEIGFNLAVL LTNLSEHMPNEPRLTRFLETASSVLNYFQPFLGRIEILGGSKRIERVYFEIKESNIEQWL KPQIRESKRAFFYSIVTEGGDKEKLEAFVNFCEDAIFEMQHASGLMAVDDGSGIGGGKSR KTAYTYMADDEENKTAKDPIRRGIQAIKYGFHLLFFVLSPTNIKNKINEIQQMSVIELIT SFFKLWFYLIFYTGYSGVYVLRYISRILMQLMSGTQSEETTVEVVEEKSGSFRMLPALPS SGMDEPPSTLTDGNNMRKNSGSPDSKHLKSNSVGDDKDETSAENHEKEDGVDGSEQQASF VDLLVGESARKDSIAGPEVLAQQQAVMAAVEAEIKQKNSVENPSAFSTIDINAYTHRALS FLARNFYNLKYVALVLAFCINFILLFYKVTTLADDLSDDGDVKEFALGSAGISNDDMDDS NSTEIADDEGVLELVHVNEDFFYMAHVMRLAALLHSLASLAMLIAYYHLKVPLAIFKREK EIARRLEFDGLYIVEQPEDDDIKSHWDKLVISAKSFPVNYWDKFAKKKVRQKYSETYDFD SISNLLGMEKTSFSTQENEERTGLINFVINIDWRYQVWKAGVTITDNAFLYSLWYFTFSI LGNFNNFFFAAHLLDVAVGFKTLRTILQSVTHNGKQLVLTVLLLTIIVYIYTVIAFNFFR KFYVQEEDDEVDKKCHDMLTCFVFHLYKGVRAGGGIGDEIGSPDGDDYEVYRIMFDITFF FFVIIILLAIIQGLIIDAFGELRDQLESVKEDMESNCFICGIGKDYFDKVPHGFDTHVQE EHNLANYMFFLMHLINKPDTEYTGQETYVWNMYQQRCWDFFPVGDCFRKQYEEELGGGGG V NT seq 15306 nt NT seq  +upstreamnt  +downstreamnt atggccgacagcgagggcagttcggaacaggacgatgtctcgtttctccggaccgaagat atggtgtgtttatcatgtactgcgaccggagagagagtttgtcttgcagcagaaggattt ggaaatcggcactgttacttagaaaatattgccgataaaaatattccacctgacttgtca caatgtgtttttgtcattgaacaagcgttatctgtgagggctttacaagaactagtgaca gctgcaagttctcaagagggaaaaggtggaactggatcaggacatcgaacattgctatac ggaaatgctattttattgcgtcatcaaaatagcgatatgtatttagcttgtctatcaaca agttcatcgaatgataaattgtcttttgacgttggtctacaagagcattcacaaggtgaa gcttgttggtggactgtgcacccagcatcgaaacaacgatcagagggtgaaaaagttcga gtcggagatgatttaattttagtgtccgtggcaactgaacggtatttgcacaccgccaaa gaaaatgagttatctgtagtaaatgcatcatttcatgtaactcattggtcagtacaacca tatggtactggtatcagcagaatgaaatacgttggttatgtttttggtggtgacgtacta agattctttcatggcggcgatgagtgcttgacaataccatcgtcgtggagcgatgtttct ggacaaaatatagtaatttatgaaggcggaagcgttatgagtcaagcaaggtcattatgg cgtttggagttggctagaactaaatgggccggtgggtttattaattggtatcatccaatg cgaataagacatctgaccactggacggtatttaggcgtcaatgaaaacaatgaattacat ttagtttgcagagaagaagccactactgcatcgtctacatttttcttacgtcaagaaaaa gacgatcaaaaaataattttagaagacaaagatctagaagtaattggtgcacctattatt aagtatggtgacagtacagtgttagttcagcattctgatacaggtttatggttaacatat aagtcttatgaaacaaaaaaaaaaggtgtcggtaaagtagaagaaaaacaagcagtatta cacgaagaaggtaagatggacgatggattagacttcagtaggagtcaagaagaagagtct agaactgctagagtgatacgcaaatgctcgtcattattcacacaatttatttctggctta gagaatttacaaagtaacagacgttcgtcattattttgttcattcgttaatctaaatgaa atggtcatgtgtctagaagatttaataaattactttgctcaaccggaagaggatatggaa cacgaagaaaaacaaaatcgattcagagcattaagaaacagacaagatttatttcaagaa gaaggcatattaaatttaatcttagaagctattgataaagttaatattatcacatctcaa ggattcatggtcagtttagctggtgatgagtctggacaaagttgggatgtgatttctggt tatttataccaattgctagctgcaattattaaaggcaatcataccaattgtgctcaattt gctaacactaatcgattaaattggttattcagccgattaggatctcaagcatccagtgag ggaactggtatgttagatgtacttcactgtgttctcatcgattctccagaagctttaaat atgatgaaagatgaacatattaaagtaataatatctcttttggaaaaacacggtcgtgat ccaaaagtgttggatgttttatgttctctgtgcgttggtaacggtgtagccgtaagaagt tcgcaaaataatatatgtgatttcttattaccaggaaaaaatttacttcttcagaccttg cttgttgaccatgtagcaagcgtacgtcccaatatttttgttggtcatgtaagtggatct gctgtctatagaaaatggtattatgaagtggcaatagatcatgtagaacaaactactcat ttaaatccacatattcgcattggatgggcaaatactgcaggttatgttccatatcctggt ggtggagaaaaatggggtggaaatggagttggggatgatttatactcttttggatttgat ggatcatatttatggacaggaggacgtaagtcagaagtgatgcctggtacacaaatttct aatattaaaaaaagtgatgtaatcggctgtgcattagatttaactattccaattataact tttacactgaacggtcaattggtccaaggcgccttcagagacttcaatttagatgggatg tttttcccagtaattagttgttcgtcaaaagtcagttgtcgtttcttattgggcggagat cacggtcgattaaagtttactccaccagatgaattttctcccctatttgaaactttactg cctcaacaaatcttaacaatcgatccgtgcttctattttggaaacctaaataaatgcgtg ctcacgggtccatggtatgttgaagacgatacagcatttgttccaaatccggtcgataca tcgatggtcaccttgccaagttacatagaaaatattaaagacaaattagcagagaatatt catgaaatgtgggcaatgaataaaattgaagctggttggcaatatggtgataaaagaaat gataccaggaagtttcatccatgtttaatacagtttgacaagttgcctccagccgagaag cgttatgattctcaattagctgtgcaaacgcttaaaacggttattgcgttaggatatcac atatctattgataatccaccgtcccgcattaaaacggtccggctgcccaacgaaccattt atgcaatccaatggatacaaaccagcaccacttgatttatctgccataattttgtcagga aaaatggaagaattaattgatcagctagctgagaatacacataatctatgggcaaaagaa agaatacagcaaggatggacatatggattaaatgaagaattacaaatgttgcgcagtcct catttagtaccgtacagcaaagtagacgacgctattaaaaaagctaatagggatacagca agcgaaacagtccgcacattattggtatatggttacaatttagatcccccgaccggagaa acaaacgaagcgacactcctaacagatgacaacactaatagatatttgacgttcagaaca tatcgtgctgaaaaaacatacgccgtttcaagcggaaaatggtacttcgaatttgagata ttgaccagtggacctatgcgggtaggatgggccaggtttacatgttctccgggttatcaa atcggcagtgacgaaaattcttgggcatttgatggctataacgaagaaaaaatttacatg gggacagccgaatcatttggtagacagtggcaagttggagacgtcgtaggagtgttttta gatttaatggaccatacaataagcttttcgatgaatggagaattactaatggatacgttg ggaggggaaactacattttctgaagtccaaggagaaggatttgtacctgcatttacgctg ggactaggacaaaaagcaaaattaacttttggtcaagacgttaactctttgaaatacttc acgacttgtgggcttcaagaaggatatgaaccattttgcgtaaacatgaagagacctgta acatactggtatactaaggatcaaccaatttttgaaaatactgatgatttttcatctgtt atcgatgttacaagaataccagctggttcagatacacctccgtgtctaaagattagtcat aatacatttgaaaccatggaaaaagctaattgggaatttttacggctatctttacctgtc atatgtctaccaagttttattgatgagcaagaaaaacaaaggagatggcaagaaataaga atcaggcaacacaggttattatcccagtctgagcatgctactcctgctcacattgaacaa ataatgaaatcaggattttcaatgagtgatataaaaggtcttcatcgaggttattcagat gatcctgtagaaaatgacgaaatgatgccaaatgctacgcctttaccaccaagaggaaaa aatcaaccaccaccgcccaggccaccacgcaaagggtcattatctaggcatgatgactta acaatcgaaaatgaagggaagttgaatcgttcatctagtgaactgaattttaacatatat aatcatcaaaatggcgatggtcaggatataaacaaggacgataagaaaaaaagagggcgt tctccatttcgatttttctcgagaaaaaaagaaggaccgtcagataatccaaaaagagca aaaacgccggatccagttaggaatgtggatagatcacgtaatgctgcccacagacctaat acattaaatgaaagagtaaccccccaaataagagtttcacaaatggatttaaaattggtt ccaccagctattcctgatagaccaggtggtccaaaagcgatgtcattcacacctacatca gcagggattgaatttgtagggaatgaaatatttgatttagaatgtttaaagttaataaat gagtattactatggtgtaagaatattccctggtcaagacccaacacatgtttacgtggga tgggttactactcaataccatcttcatactaaagatttcagccaaaatcatgttcgaaaa agtactgtaacaattgtcgatgaacataatagaattttagaaagtattgatcggcaaagc tgttacatggttcgttccgatgaattgtacaatgaagttacaaatgattcatctggaaag ggagcctcccaaggaatggccattggttgttttattgacatagctactggaatgatgtca tttacatgcgaaggaaaagaaacaagttttaaatttaaaatggaaccagatattaagtta ttccccgcaatatttgtggaagctagcagcaaagagattttacaaattgaattgggtaga acatcaaccacacttccattatctgcagctgttttacaaaattcagaacgtcatgttctt cctcagtttccaccaagattaaaagtccaatgtttaaggccacatcagtgggctagagtt ccaaacgattcattacacattcatactctgaaattatctgacattagaggatggagtata ctctgtgaagatccagtgtcgatgattgcattacacattcccgaagaagatcgatgtata gatattttagagttgattgaaatggaaaaattactatctttccatgctcacacattgact ttgtacgcggctgtgtgctaccaagccaactaccgagctgctcacatattatgtactcat gtaaatcaaaaacaattgttatatgctatatgttcagaatatatgtctggtccattacgt caaggattttatgatctcttaatagctttacatttagagtctcatgccacaacaatggag gtttgtaaaaatgaatacattatacctctgggacatgaattaactacgttgtacgatgat ccacaaatgggtcatagtttacggtcgttacaaaccgaatcagttcgacctcaaatgaaa atgactgaaatttcagacgttatcgataacgttcgtaacttatacagtccttatttccca ttacaagtagtcagagaatatgtaatggctgcgctagaagaagctgtgttagttaatcag gttcataatagagatcctattggtggatctaacgaaaatttgtttttaccgttattaaaa ttagtggatcgtcttttacttgtcggtatgttacgtgacgaggatgtagaaaaattatta ataatgattaatcctgaaacttgggatcctgaatttcaaaaagatggtcctgatgaacat aggaaaggtttattacacatgaaaatggctgagggtgccaaacttcaaatgtgttattta ttacatcatttatgtgatattcaactaaggcatagggttgaatcgataatctcatttagc tatcaatttgtcaatgatatacaaatagatcaattaagaagatataatgaaataaaacaa tcagatttaccatctgcagttgctgcaaaaaaaacaagagagttccgatgtccaccacga gaacaaatgaatgcaattttaggctttaaaaatttggacagcgatgataaagaaaattgt ttgattggtgatgatcttcgtgaaagaatgaacgagtttaatgagaaactcatgaagcaa atatctttagtagctcttcaagaatcagaagatgataaatcagatttgaataacctaaac aatgaaggtaaaataaaacagttctataattttataaacgctgtgaaagatgaaggaaat gaagatggtcttaatgaacaagaaaaaaaaataccagaagaaatatttagaaaagtttta atatccactatagtatcgtgggctgaagaaactcaaattgaaacaccaaaattagttaga gaaatgttcagtttattagttagacagtatgatagtgtaggagaattgattcgtgcgtta gagaaaacatatgtaattaactttaaaacaaaagaagacgttgctcaaatgtgggttgga cttagtcaaatccgttctttgttgcctgtgcaaatgtcacaagaagaagaagaattgatg cgagaaagattatggaaactggtaaataaccacacatttttccaacatcctgatttaata agagttcttcggatgcacgaaaatgttatggccgtcatgatgaacacactaggaaggaga gctcaagcccaatcacagccaggtggaacacctgtaacgggacaagacggagaaatcgtt ccaaaagaaaaggatacatcgcatgaaatggtcgtagcttgttgtcggttcttgtgttac ttttgccgtacatccaggcaaaatcaaaaagccatgtttgatcatttttcatttttacta gaaaatagtaacattttactttctagaccgtcattaagaggaagtacgccactcgatgtt gcttattcatcgctcatggaaaatactgaacttgcattagcgttgagggaacattatttg gaaaaaatcgcgatatatttgtctcggtgtggtttacagtcgaattcagaattgattgaa aagggatatcctgatttaggctgggatccagtagaaggggaaagatatttagattttcta cgattttgcgtttgggtcaatggagaaagcgtagaggaaaatgccaatttagttattcga ttgcttatacgcaggcctgagtgtttgggtcctgcattaagaggagaaggagaaggactt ttacgtgccataattgatgctaataaaatgtctgagagaataacagaacggaggaagttc ttagaagaatcgggaaaccaagagaatattcaactagatcatccacttccggaatccgac gaagatgaagattatattgatacaggagctgctattttaaacttttactgtactcttgtt gacttactaggacgttgtgcgccggacagttcggtaatatcactgggaaaaaatgaatct ttacgagcaagagccattcttcgatcattggtaccgctcgaagacttacatggcgttctt agtcttagatttaccctacagaatccagctgctggtcaagataggccaaagagtgatatg ccttcagggttaataccaggacacaaacaaagcgttgttctatttttagaacgtgtgtat ggtatcgaaatgcaagagttatttttcacattactcgaggaagcatttttgccagatcta cgtacagcgacaatgcttgacagaaatgacggacttgaatcagacatggcattggcaatg aatagatatattggaaattcagtattaccattactcataggtcattcgaaattctatagc gagtccgataattatgctaatttattagatgcaacgttacacactgtatacagattatct aaaaatagaatgttaacaaaaggacaacgagaagctgtttcagacttcttagtggcatta actagtcaaatgcaaccaagtatgttattaaaactactgagaaaacttacagttgatgtt tcaaatttatcggagtatacaactgtagcacttagattgttaactttgcattacgatcgg tgtgcaaaatactatgggtcaacaggcggtcaaggaatatacggagcttctagcgacgaa gaaaaacgattaacgatgatgttattcagtaacatatttgattctttgtcaaaaatggac tacgatcctgagctttttggaaaagcattaccttgtttgtcagcaattggatgtgctttg cccccagattattcattatcgaaaaatcatgatgatgaatggtatggatcaaaacaaaat attcaaggcccttccgatggaccttataacccacaaccaataaacacgaatagcattgtt cttgataatgacttgaactccattgtacataagttctcagaacattatcacgatgcatgg gcaaatcgtaaattggaaaatggatgggtttatggtgaacagtttaatgatgtcaataaa agtcatcctcggcttaaaccatacatgatgttgagtgaatacgaaaaagaattgtacaaa gaacctgtaagagaatctctcaaagcattacttgcaataggatggagtattgaacattca gagaacgatgcaccattgaacaatagaggatctgttcgacgtcaatcaaaatctaatgaa aatgtaacaccatttgactaccatccaaatcccatagacatgactaaccttacactcacc agagaaatgcaaaatatggcagaaaggttagcagagaattcccatgatatttgggctaag aagaagaaagaagaagttatgttgtgtggagggggtattcataatcaattggttccgtat gatttgctaactgataaagaaaagaagaaagaccgagaacgctcccaagagtttcttaaa tacttgcagtaccaaggttataaattacacaggcctaaccgtaatggaggaccctcagaa gctgaacaattggctgctgcgtcaacaggggaacttcgattttcatatagtttgcttgaa aaattgattcattacattgacagagcatcaataaatatgaaacttttaaaaccttcgggt acatttagcaggcgttctagtttcaaaatatgtacaagagatattaaatttttctccaaa gttgtgctaccgttagttgagaaatattttagcactcatagaaattacttcataacggtt gcaacggcttcaagtgtcttgggtgcagcttcgttaaaggaaaaggaaatggtcgctagt ttattttgtaagttagctaatcttttgagatctaaattaatggccttcggagctgatgtc cgtataaccgtacgatgtctacaagtacttgtcaaagctattgatgccaaatcactcgtg aaaaactgtccggaatttattagaacttcaatgctcacatttttccataacattgctgat gatttggaacatacaattcaaaatttgcacgatagtcgttattgctatctacgaggaact catttgaaaacatcgacttcactattttatgttaatgacgtaattttgccagtcttgtca tcactttttgatcatttagctgcatacgaatacggaaacgagctattgttgaacgaaatt caagtagccgcttataaaatgttgagtagtctgtatacccttggtacagatacatctttg acacatgatagaaaatatttaaaagtacagttggaaagacatcgtccggctttcggtagt tgtttgggtgcatttagttcaacatttcccgtggctttccttgaacctcatctgaataaa cacaaccaatattcacttcttaatcgatttgctgatagttcattggaagctcaagatata atgtcgagaatggaaggcactatgcccactctagaaacggtattaaacgaagttgatcag tttatcgaatcagaaaaaacatacgcagacgcaccacatataattgatgttattttacca ttgttgtgttcatacttaccgtactggtgggcacaaggtccagataatgttgctctgacc acaggtaatcatgtcacaatggtgactagtgaacatatgaactgcctattgaaaaatgtt ttaaaattaataaaaaaaaatattgggaacgataacgccccttggatgacgcaaattgca gcttatacacaacaaataattattaattcttcagaagaattattaaaagatccattctta ccacttgcggaacgagttaaaaaacgtacagaaacgttgtaccataaagaagagtcgtta agaggatttataaaatcgtctacagatgatacgtcccaaatcgaagctcaaatacaagaa gattggcaattagttgttagggatatttatgcgttttacccactcctcataaaatacgtg gatcttcaacgcaatcactggttacgtaataacatatcaaatgctgaagatttatacaat cacgtatctgaaatattcaacatttggtccaaatctcaatactttttacgggaagaacaa aactttatttctgcgaatgaaattgacaacatgatacttattatgccaacggctacacgg agatcggctgttatatcagaaacatcgttaggcggatcaactggaaagaaaaagaaaaaa catagggataagaaacgtgacaaggaaaaagaaattcaagcatcattgatggttgcttgt cttaaacgattactgccagttggtttaaatttgttcgcaggaagagaacaagaattagtt caacattgcaaggatagatttttaaaaagaatgccagactacgacgtgatacaatttgtc aaaattcaattgacattacccgataaattggatccggctgacgaaatgtcctggcaacac tatttatactcaaagctaggaagcaaaaaaggaactactgaaattaaaccacaacaagtc gatgaggttgcggatagaattgtcgctatggctaaagttctttatggattacacatgatt gatcatcctcagcttcaaagcaaggcgatttatcgatcagttgtatcgacgcaacgtaag agagccgtaattgcttgtttccgacaactctcactccacgctttgaccagacaccgtgca gtaaatatattcgttcgttcattttacgaactttggcttcaagatgaaaatattggacaa gaagtcatgattgaagatctcacacaatcatttgaagaggcggaacttaagaaacgtgac aaggaagaagaagaaggaatggcagatccgctaaatcaaatggttactactttttgccga ggagccatgaccgagagaagcggtgctttacaagaggaccctctttatatgtcttatgcg gatattttagctaagtcttgtggtgaagaagaagaagaaggcaataacgaagaagaaggt tcaactggtaacggagaagaagaaggcggcgcttctatccatgaacaagaaatggaaaaa caaaaactgttgtttcaccaagctcgattggccaaccgtggtgtcgcagaaatggttttg ttgcacatatcagcctgcaaaggtatacctagcgaaatggttatgaaaacgcttcaattg ggaatcgccgttctccgtggtggtaatttagaaattcaaatgggtatgttaaatcattta aaagaaaaaaaagatgttggattttttacttcagttgctggtttaatgaactcttgcagc gttcttgatttggacgcttttgaaagaaataccaaagctgagggattgggagtaggatcg gaaggcgctgctggtgaaaaaaatatgcacgatgccgagttcacttgtactctattcaga tttattcaattaacttgcgaaggccataatttagaatggcaaaattatttaagaacacaa gcaggaaatactacgactgtaaatgttgtaatttgtacggtggattatttacttagactt caggaatctataatggatttttattggcattattcaagcaaagagctaatcgatccagca ggaaaagcaaatttcttcaaagcaatcggtgtcgccagccaagtttttaatactctatct gaagtaattcaaggaccgtgtactcaaaatcaacaggccctagctcattccaggttatgg gatgccgttggagggtttttgtttttgttttcgcacatgcaggataaattatcgaaacat tctagtcaagtagatttgttgaaagaacttttgaatttacaaaaagatatgattacgatg atgctgtctatgttagaaggtaacgttgttaatggaacaattggtaaacaaatggttgac actttagtagaatcggcgtcaaatgtcgagttgatattgaaatattttgacatgttcctg aaacttaaagatttaacgagctcagcaagctttacggaaattgaccccaacaacgatggt tgggtacatccaaaagattttaaagaaaaaatggaacaacaaaaaagttatactgcagag gaaattgaatttatgttacaatgttgtgaatctaatcacgatggaaaaattgattacatt ggcttcacagatcaattccacgagccatccaaagaaattggtttcaatcttgccgtattg ttgactaacctatcggaacacatgccaaatgaacctagattaacgagattcctagaaaca gctagcagtgttttgaactatttccaaccattccttggaagaattgaaattctcggtgga agtaaacgcatagaacgggtgtactttgaaattaaagaatcaaacatcgaacagtggtta aaaccacaaattagggaatcgaaacgtgcgttcttttattcgatcgtcactgaaggtggt gataaagagaaattagaagcatttgttaatttctgcgaagatgctatatttgaaatgcaa cacgccagtggtcttatggcagttgatgatggatccggtataggtggtggaaaatctaga aaaacagcgtacacatatatggcagacgacgaagagaacaagacggcaaaagatcccatt cgaagaggcatacaggccatcaaatatggattccacctactgttcttcgtgttgtcgccc acaaacattaaaaacaaaatcaatgaaattcaacaaatgagtgtcattgaattgatcact tcatttttcaaactatggttttatttaatattctacactggatatagtggagtttacgta ttaaggtatatatctcgtattctcatgcaattaatgagtggcacgcaatctgaagaaaca actgtcgaagttgtagaagaaaagagcggatcgttcagaatgctgcctgcattaccatct tcgggaatggacgaaccaccgtcaacacttacagatggcaataatatgagaaaaaattct ggttctcctgattcaaaacatttaaaatcaaactctgttggtgacgataaagacgaaaca tcggcggaaaaccacgaaaaagaagatggcgtggatggctcggaacaacaagcgtcgttt gttgatctattagtaggcgagtcggctagaaaagattctattgccggccctgaagttttg gctcaacaacaggccgttatggcagcagtagaagcagaaatcaaacaaaagaactctgtc gaaaatcctagtgcattttctacgatcgatatcaacgcatacacgcaccgtgcattgagt tttttggcaagaaacttttataatttaaaatacgtcgcactagtattagctttctgcatt aatttcatactgttgttttacaaggtgacaactctggccgatgatttatctgacgacggg gacgtcaaagagttcgcactgggttcggctggcatcagcaatgacgacatggacgactca aatagcaccgaaatagctgacgacgaaggagtattggaacttgtgcacgtcaacgaggac ttcttttacatggcacacgttatgcggcttgcggctttgctccactctctagcatcgttg gccatgttgatagcatattaccatctgaaagttccattggccatattcaaacgggaaaag gaaatcgccaggagattagaattcgacggtctgtacattgttgaacagccggaagacgat gacataaaatcgcattgggacaagttggtgatttccgctaaatcgtttccggtgaattat tgggacaagtttgcgaagaaaaaagttcgtcaaaagtatagcgagacgtacgattttgat tccataagcaatttgttgggcatggagaagacatcgtttagcactcaggaaaatgaagaa cggaccggcttaataaatttcgttattaatatcgactggagatatcaagtttggaaagct ggggtcaccataacagacaacgcattcctgtacagtctgtggtatttcacattttcgatt ctgggcaactttaacaatttcttctttgccgctcatctactggacgtggccgttggcttc aaaacgctgagaactatcttacagtccgtaactcataacggaaaacagctggtattgacc gtcttgctcttgacgatcattgtatacatatacacggtcattgcatttaacttcttcagg aagttctacgtccaggaagaagacgacgaagtggataagaaatgtcacgacatgttgacg tgtttcgtgttccacctgtacaaaggtgtgagggccggtggtggtatcggagacgaaatc ggatcacccgacggcgacgactacgaagtttacaggataatgttcgacatcacgttcttt ttcttcgtcatcattatactgttggccatcattcaaggtttgatcattgacgcgttcgga gagctgcgtgaccaactggaaagtgtcaaggaggacatggagtccaattgtttcatttgc ggcatcggcaaagattatttcgacaaagtgcctcacggtttcgacacgcacgtacaagaa gaacacaacctcgccaactacatgtttttcctaatgcatctgatcaacaaaccggacaca gaatataccggtcaagaaacgtatgtgtggaacatgtaccagcaacggtgttgggacttc ttcccagtgggagactgtttccgcaaacagtacgaagaggagctcggcggcggaggaggc gtctga

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