Apibacter sp. B2966: G8C43_05500
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Entry
G8C43_05500 CDS
T06471
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
apib
Apibacter sp. B2966
Pathway
apib00260
Glycine, serine and threonine metabolism
apib00261
Monobactam biosynthesis
apib00270
Cysteine and methionine metabolism
apib00300
Lysine biosynthesis
apib01100
Metabolic pathways
apib01110
Biosynthesis of secondary metabolites
apib01120
Microbial metabolism in diverse environments
apib01230
Biosynthesis of amino acids
Module
apib_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
apib00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
G8C43_05500 (thrA)
00270 Cysteine and methionine metabolism
G8C43_05500 (thrA)
00300 Lysine biosynthesis
G8C43_05500 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
G8C43_05500 (thrA)
Enzymes [BR:
apib01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
G8C43_05500 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
G8C43_05500 (thrA)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
ACT_9
AA_kinase
ACT_7
ACT
NAD_binding_3
DUF5333
TaqI_C
Motif
Other DBs
NCBI-ProteinID:
QII72249
LinkDB
All DBs
Position
1278137..1280584
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AA seq
815 aa
AA seq
DB search
MKIVKFGGSSVGSGQSIQNVLSILQNKYASGEKFIVVSSAMSGVTNILTELAQIASEGKD
FKKGLIEIEQRHFTVIKEMITVKNQNPAFTQIKIFINEIEDLLQGVYSLRELSLQSKDLI
LSYGEKCSTFLLSQIAKQYFSESIYVDASLLIKTDSNFGNARVHTPVTEHLLQEFYKEHS
HQILFFTGFIASNENNRITTLGRGGSDYTAAIIAAALDAEEIELWSDVDGMLTADPRVVK
KAFSLSELSYTEAMELSYFGAKVIYPPAMIPAFRKKIPIVLKNTFNPSFKGTRIEEHTHK
NAYPIRGISSIDEISLINITGSGMIGKIGFSGKLFSLLAREHINVILITQSSSEHSITFA
IEPKDVHKAKQLFNSEFELELETNKLNPPTIEENLCVLAIVGENMKQTPGISGKLFQALG
RNGINIHAIAQGSSEYNISVIIKRKNISKALNAVHDAFFTQLTKTLHVFSVGTGNIGATL
LRQIDAQSDFLRENNGIEVKINGIANSRKMIIDEEGIDLTQWQERINKGEPSNLDEFIQK
IKLLNLSNCIFVDNTASPITGTYYKELFESNVSVVTCNKIANSSSYKDYKDLKDTARRRG
VDFFYETNVGAGLPIIRTLKDLMTSGDRIIKIEAILSGTISYIFNNFRGNTSFYEVVKKA
HELGYTEPDPREDLSGKDFMRKMMILARDAGYQIEEKDVELGAILPESCFKAPSIDDFYE
ELKKSDSYFNELKEKAENENKVLRYIGKLEDGKASVNLEFVDASHPFYNLTGSDNIISFT
TERYKFNPLVIKGPGAGAEVTAAGVFADLINVGAN
NT seq
2448 nt
NT seq
+upstream
nt +downstream
nt
atgaaaatagtaaaatttggaggatcatctgtcggttccggtcaaagtatacaaaatgta
cttagtattctgcagaacaaatatgcttcaggcgaaaaatttatagtagtatcatctgcc
atgagcggagttaccaatattttaacagaactagcccaaattgcctctgaaggaaaggat
tttaaaaaaggtcttattgaaattgaacaaagacattttacggttattaaagaaatgatt
acggttaaaaatcaaaatcctgcatttactcagattaagatttttataaacgagatcgaa
gatcttttgcaaggagtctatagcttgagggaactcagtcttcaaagcaaagatcttatt
ttaagttatggagaaaaatgctccacttttttattgagtcaaatagccaaacaatatttt
tcagaaagtatttatgtagatgcttcactccttataaaaacagacagcaattttggaaat
gcccgagtacatactcccgttacagaacatttattgcaagagttttacaaagagcattca
catcaaatcctgttttttacaggttttatagcctccaatgaaaacaatcgaattacgaca
ttaggaagaggaggcagtgattatacggcggccataatagctgccgccttagatgcagaa
gaaattgagctttggtctgatgtagacggtatgttaaccgcagatcctcgtgtcgtaaaa
aaggctttttcattatctgaactttcctatacggaagctatggaattatcttattttgga
gcgaaagttatctatcctccagccatgattccggcttttcgaaaaaaaatacctattgta
ttgaaaaacacctttaatccttcttttaaaggaacaaggattgaagaacatactcataaa
aatgcatacccgattcggggtatttcttccatagatgaaatcagcctgatcaatattaca
ggaagcggaatgattggcaaaattggcttcagcggaaaacttttttctttattagcacgc
gaacatattaatgtaatccttattactcaatcgtcttccgaacatagtattacatttgcc
attgagcccaaggatgttcataaagcaaaacagcttttcaacagtgaatttgagttggaa
ctggaaaccaataaattaaatccgcctaccattgaagaaaatttatgtgtattagccata
gttggcgaaaatatgaaacaaaccccggggatatcgggcaagcttttccaagctttagga
cgtaatggaatcaacatacatgctattgcacaaggttcatccgaatacaatatttcggta
ataataaaacgtaaaaatatatctaaagctctgaatgctgttcatgatgcgtttttcact
caactaaccaaaacacttcatgtattcagtgtaggaacaggaaatatcggggcaaccttg
ttgcgacaaatcgatgctcaaagtgattttttacgtgaaaacaatggtattgaagtaaag
ataaacggaatagctaattccagaaaaatgattattgacgaagaaggcattgatcttaca
caatggcaagaaagaataaataagggagaaccctctaatttggatgaatttatccaaaaa
attaagttgttaaatctttccaactgtatttttgtcgataatactgcaagtccaataacc
ggaacgtattacaaagaacttttcgaatctaatgtttcggtagttacctgtaataaaata
gctaattcttcttcatataaagattataaagatttaaaagatactgccagaagaagaggc
gtcgatttcttttatgaaacgaatgtaggagccggattgcctatcatacgaactttaaag
gatttaatgaccagcggggacaggatcatcaaaattgaggctattttaagcggtactatt
tcttatatatttaacaattttagaggcaatacttctttttatgaggttgttaaaaaagct
catgaattaggctatacggaaccggatcctcgagaggatttgagcggaaaagattttatg
cgtaaaatgatgattctcgcacgtgatgccggatatcaaattgaagaaaaagatgttgag
ttaggagctatccttcctgaaagctgtttcaaagctccctcgattgatgacttttatgaa
gaattaaaaaaatctgattcttatttcaacgagctgaaagaaaaggctgaaaatgaaaat
aaagtgttacgatatatcggaaagttggaagatggaaaggcttccgtaaatttggaattc
gtagatgcttctcatcctttttacaatttaacgggtagtgataatattatctcatttaca
acggaacgatataaatttaatccattggtaataaaaggtccgggagcaggtgctgaagtt
accgcagcgggggtttttgctgatcttattaatgttggagccaattaa
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