Actinobacillus pleuropneumoniae JL03 (serotype 3): APJL_0015
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Entry
APJL_0015 CDS
T00644
Symbol
murF
Name
(GenBank) UDP-MurNAc-pentapeptide synthetase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
apj
Actinobacillus pleuropneumoniae JL03 (serotype 3)
Pathway
apj00300
Lysine biosynthesis
apj00550
Peptidoglycan biosynthesis
apj01100
Metabolic pathways
apj01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
apj00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
APJL_0015 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
APJL_0015 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
APJL_0015 (murF)
Enzymes [BR:
apj01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
APJL_0015 (murF)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ABY68621
UniProt:
B0BRH3
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All DBs
Position
15135..16529
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AA seq
464 aa
AA seq
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MIKLTTNEIAGILNAQLIGDGNVLVETTSTDTRQAVENGLFFALKGENFDAHHYLANAVE
QGSVAVVVERECEISVPQIVVKDTRLALGELAKWLKAKLNPKTVAMTGSSGKTTVKEMTA
KILQKMTACEDEVLYTFGNLNNDLGVPMTLLRLTPQHKFAVVELGANHIGEIAYTTEITQ
PDACLVNNVAAAHLEGFGSLEGVAQAKGEIYRGLKAGGKAIVNQAFYYPQWQKEIGEHEL
QSFSYIGSDQDSYADFWAENVELGLAGSRFTLHSPQGEIEINLPYLGAHNISNALAATSL
AMAVGAGLNAVKAGLEQRSQVKGRLYPVEVNQHCLLIDDTYNANVDSMKSAVAVLKNYPA
FRIFAVGDMAELGDESAACHQQVADFVREANLDLVVSFGKQSAVISHDTAHHFTDKQAMH
DFLLPIISQKIAEKQPLVLLAKGSRSQKMETLISALCLSLGVSF
NT seq
1395 nt
NT seq
+upstream
nt +downstream
nt
atgataaaactaacaacaaatgaaattgccggcattcttaatgcacagctaattggtgat
ggcaatgtgctggtggaaactactagcaccgatactcgacaagcggtcgaaaacgggctg
ttttttgcgttaaaaggcgagaactttgatgcgcaccattacttagctaatgcggtggaa
caaggcagtgtggcagtagtggttgagcgtgaatgtgagatttccgtaccgcaaattgtg
gtgaaagatacacgccttgcgttaggcgagttagccaaatggttaaaagcgaaacttaat
ccgaaaaccgtggcgatgaccggttcttcaggcaaaaccaccgtaaaagaaatgacggca
aaaattttgcaaaaaatgaccgcttgtgaagatgaagtgctttatacctttggcaaccta
aataacgacctcggtgtgccgatgaccttgttacgtttaacgccgcaacataaatttgcg
gtggtggaactcggggcaaaccatatcggcgaaatcgcttataccacagaaattactcag
ccggacgcttgtttagtgaataacgttgccgcggcgcatttagaaggtttcggctcactc
gaaggtgtagcgcaagcaaaaggcgaaatttatcgaggcttaaaagccggcggtaaagcg
attgtgaatcaagccttttattatccgcaatggcaaaaagaaatcggcgagcatgagcta
caatcatttagctatatcggttcggatcaagattcgtatgcggatttttgggcggaaaat
gtggaattgggtttagccggatctcgctttaccttacattctccgcaaggtgaaatcgaa
attaatttgccttacttaggcgcacataatatcagcaacgctttagcagcaacttcgctc
gctatggcggtcggtgcgggtttaaatgcggtcaaagccggattggagcaacgctcgcaa
gttaaaggtcgcttgtatccggttgaagttaatcagcattgtttattgattgatgatacc
tataacgccaatgtcgattcgatgaaatcggcggtggcggtgttaaaaaattatccggcg
ttccgtatttttgcggtcggcgatatggcggaactcggcgatgaaagtgcggcttgtcac
caacaagtggcggatttcgtacgcgaggcaaatttagatttagtggtgagtttcggtaag
caaagtgcggtaattagtcatgatacggcacatcattttaccgataaacaagcgatgcac
gatttcttattgccgattatttcgcaaaaaattgcggaaaaacaaccgcttgtgttattg
gcaaaaggctctcgcagccaaaaaatggaaacgttgatttccgctttatgcctttctttg
ggcgtttctttttaa
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