Actinobacillus pleuropneumoniae JL03 (serotype 3): APJL_0140
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Entry
APJL_0140 CDS
T00644
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
apj
Actinobacillus pleuropneumoniae JL03 (serotype 3)
Pathway
apj00290
Valine, leucine and isoleucine biosynthesis
apj00660
C5-Branched dibasic acid metabolism
apj01100
Metabolic pathways
apj01110
Biosynthesis of secondary metabolites
apj01210
2-Oxocarboxylic acid metabolism
apj01230
Biosynthesis of amino acids
Module
apj_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
apj00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
APJL_0140 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
APJL_0140 (leuC)
Enzymes [BR:
apj01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
APJL_0140 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
APJL_0140 (leuC)
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Gene cluster
GFIT
Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
ABY68744
UniProt:
B0BS44
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All DBs
Position
complement(155372..156781)
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AA seq
469 aa
AA seq
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MAKTLYEKLFDAHVVYEAAGETPILYINRHLIHEVTSPQAFDGLRVAGRQVRQIGKTFGT
MDHSISTQVRDVNKLEGQAKIQVLELAKNCEASGISLFDMQTKEQGIVHVMGPEQGLTLP
GMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQARAKSMKVEVRGKVNPGITA
KDIVLAIIGKTTMAGGTGHVVEFYGEAIRDLSMEGRMTVCNMAIEFGAKAGLVAPDETTF
AYLKDRPHAPKGKDWDDAVEYWKTLKSDDDAVFDSVVVLEAKDIAPQVTWGTNPGQVIGI
DQVVPNPQEMADPVTKASAEKALAYIGLDANTDMKNIPVDQVFIGSCTNSRIEDLRAAAA
VMKGRKKADNVKRVLVVPGSGLVKEQAEKEGLDKIFIEAGAEWRNPGCSMCLGMNDDRLG
EWERCASTSNRNFEGRQGRNGRTHLVSPAMAAAAAMFGKFVDIRHVELN
NT seq
1410 nt
NT seq
+upstream
nt +downstream
nt
atggcaaaaacattatacgaaaaactatttgatgcccacgttgtatatgaagccgcaggc
gaaacgccgattctttatatcaaccgtcacttaattcacgaagttaccagcccgcaagcg
tttgacggtttacgtgttgccggtcgccaagtacgccaaatcggtaaaacgttcggtaca
atggatcacagtatttctacccaagtacgtgatgtgaataaattagaaggtcaggcgaaa
atccaagttttagaattagcgaaaaactgtgaagcaagtggtatctcgttattcgatatg
caaaccaaagaacaaggtatcgtacacgtaatgggaccggagcaaggtttaaccctaccg
ggtatgacgattgtctgcggtgactcacacaccgcaacacacggtgctttcggtgcgctt
gcgtttggtatcggtacatcggaagtggaacacgtgcttgcaactcaaaccttaaaacaa
gcgcgtgcaaaaagtatgaaagtggaagttcgcggcaaagtgaacccgggcattaccgca
aaagatatcgtgcttgcaattatcggtaaaacaaccatggcgggcggtaccggtcacgtg
gtggagttctacggtgaagcgattcgtgatttatcaatggaaggtcgtatgacggtatgt
aatatggcgatcgaattcggcgctaaagccggtttagtcgcaccggacgaaaccaccttc
gcttacttaaaagatcgtccgcacgcaccgaaaggcaaagattgggacgatgcggtcgaa
tattggaaaaccttaaaatcagacgatgatgcggtctttgattcagtcgttgtattagaa
gcgaaagatattgcgccgcaagtcacttggggaaccaatccgggacaagtcatcggtatt
gaccaagtggtaccgaatccacaagaaatggcggatccggtcactaaagcttcagcggaa
aaagcgctcgcatatatcggcttagatgcgaataccgatatgaaaaacatccctgtggat
caagtatttatcggctcttgtactaactctcgtattgaagacttacgtgcagcggcggca
gtaatgaaaggtcgtaaaaaagcggataacgtaaaacgtgtgctagttgtaccgggttcg
ggtttggtaaaagaacaggcggaaaaagaaggcttagataagatctttatcgaggctggc
gcagaatggcgtaatccgggctgttcaatgtgtttaggtatgaatgatgaccgtttaggc
gaatgggaacgttgtgcttcaacctctaaccgtaactttgaaggtcgccaaggtcgtaac
ggtcgtacccacttggttagcccggcaatggcggcagcggcggcaatgttcggtaaattt
gtcgatattcgtcacgtggaattaaattaa
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