Actinobacillus pleuropneumoniae JL03 (serotype 3): APJL_1439
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Entry
APJL_1439 CDS
T00644
Symbol
gshA
Name
(GenBank) gamma-glutamylcysteine synthetase
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
apj
Actinobacillus pleuropneumoniae JL03 (serotype 3)
Pathway
apj00270
Cysteine and methionine metabolism
apj00480
Glutathione metabolism
apj01100
Metabolic pathways
apj01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
apj00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
APJL_1439 (gshA)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
APJL_1439 (gshA)
Enzymes [BR:
apj01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
APJL_1439 (gshA)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Glu_cys_ligase
ATP-grasp_6
RimK
ATP-grasp_3
ATPgrasp_ST
GARS_A
Dala_Dala_lig_C
Motif
Other DBs
NCBI-ProteinID:
ABY69993
UniProt:
B0BR08
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All DBs
Position
1581826..1584099
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AA seq
757 aa
AA seq
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MKLQQLIKTHHLGLLFQQGKFGIEKESQRIDNKGNIVTTAHPSVFGNRSYHPYIQTDFAE
SQLELITPPNDKLENTYRWLSAIHEVTLRSLPDDEYIFPFSMPAGLPPESEIKEAQLDNE
WDVKYREHLSAIYGKYKQMVSGIHYNFQISDEFVESAFALQTEYPNKIAFRNALYMKLAN
NFLRYQWILVYLLAATPTVEAQYFGENRPLAEGQLVRSLRSGPYGYVNAPHIVINHDSLQ
QYVESLEHFVATGDLLAEKEFYSNVRLRGAKKARELLEKGVKYAEFRLFDLNPFSPYGIE
LADAKFIHLFLLAMLWMDETSGQREVEIGTQKLYQVALEDPRSHTAFQAEGEAILNLMLA
MLDDLSVPQNEKDLLQQKLAQFADPSQTVNGRLLAAIEQAGSYKALGAQLAQQYKAQAFE
RFYAISAFDNMELSTQALLFDAIQQGLQIELLDENDQFLALKFGDHLEYVKNGNMTSHDQ
YISPLIMENKVVTKKVLAKAGFNVPKSIEFTSVEQAVAHYPLFEGKAMVIKPKSTNYGLG
ITIFQQGVTDKADFAKAIEIAFREDKEVMVEDYLVGTEYRFFVLGDETLAVLLRVPANVK
GDGIHTVRELVEAKNSDPLRGDGSRSPLKKIALGDIELLQLKEQGLTPDSIPADGQIVQL
RANSNISTGGDSIDMTDQMHDSYKQLAVGIAKEMGAKVCGVDLIIPDLTKAAEPSLRSWG
VIEANFNPMMMMHIFPYQGKSRRLTKAVLKMLFPELP
NT seq
2274 nt
NT seq
+upstream
nt +downstream
nt
atgaaattacaacaactgattaaaactcatcaccttggtttactatttcaacaaggtaaa
tttggcatcgaaaaagaaagccaacgcattgataataaagggaatattgttactaccgcc
catcctagcgtttttggtaaccgcagttatcatccgtatattcaaaccgattttgcagaa
agtcagttagaacttatcacaccgccaaacgataaattggaaaacacatatcgttggcta
tccgctattcatgaggtaacgctacgttcattacctgatgatgaatatattttcccattc
agtatgcctgccggtttaccaccggaatccgagatcaaagaagcacaattagataacgaa
tgggacgtgaaatatcgtgaacacctttctgccatttatggcaaatacaaacagatggtg
agcggtattcattacaatttccagatttctgacgagtttgtcgagagtgcttttgcgtta
caaacggaataccccaataaaattgcgttccgcaatgcgctatatatgaaattagccaat
aactttttacgttatcaatggattttagtttatttgcttgccgcaacaccaaccgtagaa
gcgcaatattttggcgaaaatcgaccgcttgcagaagggcaattagtacgtagtttacgt
tccggcccttatggttatgtaaatgcgccacatattgtgatcaaccacgacagcttacaa
caatatgtcgagtcgctagaacattttgtagcaaccggcgatttgttggcagaaaaagaa
ttctattcaaacgttcgtttacgtggtgcgaaaaaagcacgcgaattgcttgagaaagga
gttaaatatgcggaattccgtttatttgatcttaatccgttctcgccttacggtatcgag
cttgcagacgcgaaatttattcatctgttcttacttgcgatgttgtggatggatgaaaca
agcggtcaaagagaagtcgaaatcggcacacaaaaactataccaagttgcccttgaagat
cctcgttcgcacactgcgttccaagcagagggtgaggcgatccttaacctgatgctggca
atgctggacgatctttctgtaccacaaaacgagaaagatttattacaacaaaaactggcg
caatttgctgatccgagccaaacggtaaacggtcgtttattagccgcaatcgaacaagcc
ggcagctataaagcactcggtgcacaacttgctcaacaatataaagcgcaagcattcgag
cgtttttatgcgatttccgctttcgataatatggagctttctacacaggctttgttattt
gatgcaatccaacaaggcttacagatcgagttgcttgatgaaaacgatcagttcctcgca
ctcaaattcggcgatcatctcgaatatgtgaaaaacggcaatatgaccagccacgatcag
tacatttcgccattaatcatggaaaataaagtcgtaaccaaaaaagtattggcgaaagcc
ggttttaacgtaccgaaaagtattgaatttacctcggtagaacaagcggtggcacactat
ccgttatttgaaggtaaagcgatggtaattaagccgaaatcaactaattacggcttaggt
attacaattttccagcaaggcgtgacggataaagccgactttgccaaagcgattgaaatt
gcgttccgtgaagataaagaagtgatggtggaagactatttagtcggcaccgaataccgt
ttctttgtgttaggcgatgaaacactggcggtattgttacgtgtgccggcaaatgtgaaa
ggtgacggcatacatacagtgcgtgaattggtggaagcgaaaaacagtgatccgctacga
ggtgacggctctcgttcaccattgaagaaaatcgccctcggtgacattgaattgcttcag
cttaaagagcaaggtttaacgcctgattcgattccggctgacgggcaaatcgtacaatta
cgtgccaactctaatattagtaccggcggcgattcaatcgatatgaccgatcaaatgcat
gacagttataaacaattagcggtcggtattgccaaagagatgggggcaaaagtctgcggt
gtggatttaatcattccggatttaaccaaagccgccgagccgtctctgcgttcatggggg
gtgattgaagcaaactttaatccgatgatgatgatgcatattttcccttaccaaggaaaa
tctcgccgcttaaccaaagccgtgttaaaaatgctgttcccagaactgccttaa
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