Actinobacillus pleuropneumoniae L20 (serotype 5b): APL_0393
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Entry
APL_0393 CDS
T00476
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
apl
Actinobacillus pleuropneumoniae L20 (serotype 5b)
Pathway
apl00290
Valine, leucine and isoleucine biosynthesis
apl00620
Pyruvate metabolism
apl01100
Metabolic pathways
apl01110
Biosynthesis of secondary metabolites
apl01210
2-Oxocarboxylic acid metabolism
apl01230
Biosynthesis of amino acids
Module
apl_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
apl00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
APL_0393 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
APL_0393 (leuA)
Enzymes [BR:
apl01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
APL_0393 (leuA)
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GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
NAD_binding_10
Motif
Other DBs
NCBI-ProteinID:
ABN73497
UniProt:
A3MZB1
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All DBs
Position
447202..448743
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AA seq
513 aa
AA seq
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MSNIIIFDTTLRDGEQSLKASLTVKEKLQIALALERLGVDVMEVGFPVSSAGDFESVKTI
AQHIKNSRVCALSRAVDKDIDVAAEALKVAEAFRIHTFIASSAIHVESKLKRSFDDVVEM
AVHAVKRARNYTDDVEFSCEDAGRTGIDNICRIVEAAINAGATTVNIPDTVGYCLPYQYG
EIIANVMNRVPNIDKAVVSVHCHNDLGMATANSLTAVLNGARQIECTINGIGERAGNTAL
EEVVMAIKTRQDMFNGRDTRINTQEIHRVSQMVSQLCNMPIQPNKAIVGSNAFAHSSGIH
QDGMVKNKNTYEIMSPETIGLKKEKLNLTARSGRAAVKNHMSEMGYQENDYDLDKLYDAF
LKLADKKGQVFDYDLEALAFIDMQAGDEGRLHLDVITSQMISHLPASAFVQVELDGEKLS
QVSSGGNGPVDAVFNAILAITGMDIKMLHYNLTAKGEGAEALGQVDIVVEHEGRRFHGVG
LATDIVESSARALIHVINAIYRAHKVADLKAKK
NT seq
1542 nt
NT seq
+upstream
nt +downstream
nt
atgagtaacattattatttttgatacgacattacgtgacggtgaacaatcgcttaaagca
agtttaaccgtaaaagaaaaactacaaattgcgttagcattagagcgtttaggcgttgat
gttatggaagtcggttttccggtttcatcggcaggggatttcgagtcggtaaaaaccatt
gctcaacacattaaaaacagccgtgtttgcgcattatcccgcgcagtggataaagatatt
gatgtggcggcggaagcattgaaagtcgcagaagcatttcgtattcatacatttatcgcc
agttccgctattcatgttgagtctaaattaaaacgttcgtttgatgatgtcgttgaaatg
gcggtgcatgcggttaaacgtgccagaaactataccgatgatgtggagttttcctgtgaa
gatgcgggacgtaccggtattgataacatttgtcgtattgtcgaagcggcaatcaatgcc
ggtgcgactacggtaaatattccggatacggtcggttactgtttaccgtatcagtacggc
gagattatcgccaatgtgatgaaccgtgtgccgaatattgataaagcggttgtttcggtg
cattgtcataacgatttaggtatggcgacggcaaactcgctcacggcagtgttaaatggt
gcgagacaaatcgaatgtacgattaacggtatcggcgagcgtgcggggaataccgcatta
gaagaagtggtcatggcaatcaaaactcgccaagatatgttcaatggtagagatacgcgc
attaacacgcaagaaattcatcgtgtcagccaaatggtcagccaattatgtaatatgccg
attcaaccgaataaagcgattgtcggttcgaatgcctttgcccattcatccggtatccac
caagacggtatggtaaaaaataaaaatacctatgaaattatgtcgcctgaaaccatcggt
ttgaagaaagaaaaattaaatttaaccgcccgttcaggacgtgccgccgtgaaaaatcat
atgagcgaaatgggttatcaagaaaacgactatgatttggataaactttatgacgcattc
ctaaaattggcggataagaaaggtcaagtgtttgattacgatttagaagcgcttgctttt
attgatatgcaggcaggtgatgaaggcagattacatttagacgtgattacttcgcaaatg
attagccatttaccagcttcggcatttgttcaagtcgaattagacggtgaaaaattaagc
caagtttccagtggcggtaacgggccagtcgatgcggtctttaatgcgattctagccatt
acggggatggatattaaaatgttacattataaccttaccgcaaaaggcgaaggtgcggaa
gcattaggtcaagtggatattgtggttgaacacgaaggtcgccgcttccacggtgtcggt
ttggcaaccgatattgtcgagtcttcggcgcgtgcattaatccatgtgatcaatgcgatt
tatcgagcgcataaagtggcggatttaaaagctaaaaaataa
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