Actinobacillus pleuropneumoniae L20 (serotype 5b): APL_0632
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Entry
APL_0632 CDS
T00476
Symbol
folC
Name
(GenBank) folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
apl
Actinobacillus pleuropneumoniae L20 (serotype 5b)
Pathway
apl00790
Folate biosynthesis
apl01100
Metabolic pathways
apl01240
Biosynthesis of cofactors
Module
apl_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
apl00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
APL_0632 (folC)
Enzymes [BR:
apl01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
APL_0632 (folC)
6.3.2.17 tetrahydrofolate synthase
APL_0632 (folC)
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
ABN73734
UniProt:
A3MZZ8
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Position
719517..720821
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AA seq
434 aa
AA seq
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MMNTLTVPTINDCLAIWLDYLEKSHFKPIDMGLERIKGIAQELDLLQPAPYVITVAGTNG
KGSTCRLLEVALLKAGYRVGVYSSPHLIRYNERVRIQGDLLNDEAHVQSFVKIQQKKTAS
LTYFEFSTLSALQLFKDANLDIVILEVGLGGRLDATNIVDPNLAVITSIDIDHVEFLGDN
REDIGREKAGIFRENIPVIIGEPDCPRSILQQAKALNCQVVRRNINWKYSVENNHFHWQS
ESIDWQDLPMPQIPIPNAGTALAALAQLPFEINEQVVRAALQEAQMTARFQTLNEQNFAN
FSGKRPLAQVIIDVGHNPHAAKYLAERLTSLKQPNQKIYAVFSALVDKDLSGIVEPLENV
IDEWHCAGLAGYRGQSGEEVYQKLAKVLPNSTACYYRTVPEAAESLFAKTSKTDIILIFG
SFHTVSDFLVWIGK
NT seq
1305 nt
NT seq
+upstream
nt +downstream
nt
atgatgaatactttaactgttccgactattaatgattgcctcgccatatggttggattac
ttagaaaaatcacattttaagccgattgatatgggcttagagcgcattaaaggcatagca
caagaattagacttacttcaaccggcgccttatgttatcaccgttgccggtactaatggt
aagggttcaacttgtcgtttattagaagtagctttgctaaaagccggttatcgagtcggc
gtctattcatcgcctcacctaattcgttataacgaacgggtaagaattcaaggcgactta
ctcaatgacgaagcgcacgtgcaatcatttgtaaaaatccaacaaaaaaagaccgcttct
ttaacttattttgagtttagtacgctttcggcattacaactttttaaagatgcaaattta
gatattgtgattttagaagttggacttggaggacgtttagatgcaaccaatattgttgat
ccgaatttagctgtcatcacatctattgatattgatcacgttgagtttcttggtgataac
cgagaagatatcggtcgagaaaaagcaggcattttccgtgaaaatataccggtgattatc
ggtgaaccggattgtccgaggagcattttacagcaagcgaaagcacttaattgccaagtg
gttagacgcaatataaattggaaatattccgtagaaaataaccacttccactggcaatcg
gaatctattgattggcaagatttaccgatgccgcaaattccgattccgaatgccggtacc
gctttagccgcgttggctcaacttccgtttgaaattaatgaacaagtggttagagccgca
ctgcaagaagcgcaaatgaccgctcgtttccaaacgctaaacgaacaaaattttgcaaac
ttttccggaaaacgaccgcttgctcaagtaatcattgatgtcggacacaatccgcatgcg
gcaaaatatttggcagagcgactaacgtcactgaaacagccgaaccaaaagatttatgcg
gtatttagcgcattagttgataaagacttaagcggcatcgtagagccattagaaaatgtg
attgacgaatggcattgtgccggtttagccggataccgcgggcaatcgggtgaagaggtt
tatcaaaaacttgcaaaagttttaccaaattcgaccgcttgttattaccgaaccgttccc
gaagcggccgaatcattattcgccaaaacgagcaaaaccgacattatcctgattttcggc
tcattccacactgtgagcgattttttggtttggattgggaaataa
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