Anas platyrhynchos (mallard): 101789513 Help Entry 101789513         CDS       T02816                                  Symbol RYR3 Name (RefSeq) ryanodine receptor 3 isoform X2   KO K04963   ryanodine receptor 3 Organism apla  Anas platyrhynchos (mallard) Pathway apla04020   Calcium signaling pathway apla04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:apla00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     101789513 (RYR3)    04020 Calcium signaling pathway     101789513 (RYR3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:apla04040]     101789513 (RYR3) Ion channels [BR:apla04040]  Voltage-gated cation channels   Ryanodine receptor    101789513 (RYR3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR RR_TM4-6 MIR Ins145_P3_rec SPRY RIH_assoc Ion_trans EF-hand_7 EF-hand_1 EF-hand_6 EF-hand_8 TBK1_ULD RNA_pol_Rpc82 Motif Other DBs NCBI-GeneID:  101789513 NCBI-ProteinID:  XP_027314641 Ensembl:  ENSAPLG00000005134 LinkDB All DBs Position 5:complement(40004908..40224356) Genome browser AA seq 4888 aa AA seqDB search MAEGGEGGEDEIQFLRTDDEVVLQCVASVHKEQRKFCLAAEGLGNRLCFLEPTSEAKYVP PDLCICNFVLEQSLSVRALQEMLANTGDNAGEGFIKKAAQGGHRTLLYGHAILLRHSFSE MYLTCLTSSRSQTDKLAFDVGLRENAAGEACWWTIHPASKQRSEGEKVRIGDDLILVSVS SERYLHLSMSNGSIQVDASFMQTLWNVHPTCSGSSITEGYLLGGHVVRFFHGHDECLTIP STDQNDSQQKKVLYETGGAGVRARSLWRVEPLRISWSGSNIKWGQPFRLRHITTGMYLAL NDDEGLVMLDREKSDTTSSAFCFRASKELKEKQDSTLKRDIDGMGVPEIKYGDSVCFVQH VASALWLTYKAQDAKSARLGPLKRKVILHQEGHMDDGLTLQRCQHEESQAARIIRNTTSL FSQFIRYGNNRTLSPIALPVEEMAQTLQDLITYFQPPEEDLEHEDKQSKLRSLKNRQNLF KEEGMLALVLNCIDRLNDYNSAAHFAEIAREENGTTWKEILNLLYKLLAALIRGNRNNCT QFSSNLDWLISKLDRLESSSGILEVLHCILIESPEALNIIAEEHIKSIISLLDKHGRNYK VLDVLCSLCVCNGVAVRANQNLICDNLLPRRDLLLQTRLINDVTSIRPNIFLGVAEGSAQ YKKWYFELIIDQVDPFLTAEPTHLRVGWASTSGYAPYPGGGEGWGGNGVGDDLYSYGFDG LHLWSGRVPRAVASVNQHLLSSDDVVSCCLDLGVPSISFRINGQPVQGMFENFCTEGFFF PVVSLSAGVKARFLLGGRHGEFKFLPPAGYAPCYEALLPKEKMKLEPVKEYKRDSDGVRD LLGTTQFLSQASFIPCPIDTSQIALPFHLEKIRDKLAENIHELWGMNKIELGWTYGKIRD DNKRHHPCLVEFSKLPETEKNYNLQMSTETLKTLLALGCHIVHANPAAEEDLKKVKLPKN YMMSNGYKPAPLDLSEVKLLPSQEFLVDKLAENAHNVWAKDRIKQGWTYGIQQDLKNKRN PRLVPYALLDERTKKSNRDSLREAVRTFAGYGYSVEPPDQEIADQTTEKVSIDKIRFFRV EQSYAVKSGKWYFEFEAVTGGDMRVGWARPGCRPDIELGADDQAFVFEGSKGQRWHQGSG FFGRSWQPGDVVGCMINLDDKSIIFTLNGELLITSKGSELAFADFGIESGFVPICALGLS QIGRMNLGMDASTFKYYTMCGLQEGFEPFAVNMNRDVAMWFSKRLPTFVNVPKNHPHIEI WRIDGTIESPPRLKVTHKTFGTQNSNSDMIYCRLSMPIEFRSSFNFGMGVENASSDIFQK RKHSQEISVPSTTYFYSLRIFAGQDPSCVWVGWVTPDYHFYSENFDLNKNCTVTVTLGDE RGRVHESVKRSNCYMVWGGDITSNSQRSGRSNVDLEIGCFVDLATGMLSFTANGKELGTC YQVEPNTKLFPATFVQPTSTNLVQFELGKLKNTMPLSAAIFKSEERNPIPQCPPRLDVQT ITPVLWSRMPNSFLKVETERVSERHGWVVQCLEPLQMMALHIPEENRCVDILELCEQEDL MKFHYHTLKLYSSVCALGNTRVAYALCSHVDVSQLFYTIDNQYLPGLLRSGFYDLLISIH LEHAKQAKLMMNNEFIIPVTEETRTIRLYPDETKKHGLPGVGLSTCLKPSFHFSTPCFIV TSEEHQTSSPEIPLDTLKSKAISMLTEAVQCSGTHIRDPVGGHITFQFVPVLKLIATLLI MGVFDDDDVKQVLILIDPNVFGDHKEETEEGTEKEEVTQVEEKAVEAGEKAIKETKAPTT GLLQTRLPESVKLQMCHLLNYFCDCELQHRVEAIVSFADRYVSKLQYNQKYRYNELMQAL NMSAALTAKKTKEFRSPPQEQINMLLNFQLGEDCPCPEEIRDELYDFHDDLLIHCGIPLE EEEEEEEDSTLTGKLRSLIYKIKGPPKAEKVEPREEEEKSPTTLKELISQTMVRWSQEDQ IQDPELVRIMYTLLRRQYDSIGELLQALRKAYTISAVSVKDTINLLAALGQIRSLLSVRM GKEEELLMINGLGDIMNNKVFYQHPNLMRVLGMHETVMDVMVNVLGGDKSQQIAFPKMVA SCCRFLCYFCRISRQNQKAMFEHLSYLLENSSVGLAFPSMRGSTPLDVAAASVMDNNELA LALEEPDLDKVVTYLAGCGLQSCPVLLAKGYPDIGWNPIEGERYLSFLRFAVFVNSESVE ENASVVVKLLIRRPECFGPDLRGEGGNGLLAAMQEAIRISENPSRDLPSQGYKREGDEEE EEEEIVHMGNAIMSFYSALIDLLGRCAPEMHLIQSGKGEAIRIRSILRSLVPTEDLVGII SIPLKLSTVNKDGTVNEPDMSANFCPDHKAPMVLFLDRVYGIKDQTFLLHLLEVGFLPDL RASASLDTVSLSTTEAALALNRYICSAVFPLLKRCAPLFSGTEHHASLVDSMLHTIYRLS KGRSLTKAQRDTIEECLLAICHHLRPSMLQQLLRRLVFDVPLLNEYCKMPLKLLTNHYEQ CWKYYCLPSGMGSYGIAAEEELHLTEKLFWGIFDSLSHKFLSLLQKYDPELFRMALPCLS AIAGALPPDYLDTRIRSTLEKQTSVDPEGNFDPKPVSTANLVLPEKLEYIVSKYAEHSHD KWAFDKTNNGWKYGVSLDENTKTHPLIRPFKTLTEKEKEIYRWPARESLKTMLAMGWSLE RTKEGGETILHQRENEKLRSISQSSQGNGYSPAPLDLSNVVLSRELQGMVEVMAENYHNI WAKKKKMELESKGGGSHPLLVPYDTLTAKEKSRDREKAQELFKFLQVNGIIISRGLNDMD LDASSMEKRFAFKFLKKILKYVDSAQEFIAHLEAIVTSGKTEKSPHDQEIKFFAKVLLPL VDQYFTNHCLYFLSSPTKTLSSSGYASNKEKEMVASLFCKLAALVRHRISIFGSDSTTMV NCLHILAQSLDTRTVMKSGSELVKAGLRAFFENAAEDLEKTSENLKLGKFTHSRTQIKGV SQNINYTTVALLPVLTSIFEHISQYQFGVDLLLGDVQVSCYRILCSLYSLGTGKNIYVER QRPALGECLASLAAAIPVAFLEPSLNHYNPLSVFNTKSARERAILGMPDTVEEMCPEIPQ LDGLIKEINDLAESGARYTEMPHVIEVILPMLCNYLSYWWERGSESVPESAGPFCTMITS EHLSIILGNILKIINNNLGIDEASWMKRIAVYAQPIISKARPDLLKTHFIPTLEKLKKKA IKIVMEEEQLKADSKTDTQEAELLILDEFAVLCRDLYAFYPMLIRYVDNNRANWLKKPDA DSDELFRMVAEVFILWCKSHNFKREEQNFVIQNEINNLAFLTGDTKSKMSKQSARRGMAM QVKSGGQDQERKKSKRRGDLYSIQTSLIVAALKKMLPIGLNMCTPGDQELISLAKTRYSH RDTDEEVKEHLRNNLHLQEKSDDPAVKWQLNLYKDILKNDEPSDPEKNVERVQRISAALY HLEQVEQPLRSKKAVWHKLLSKQRKRAVVACFRMAPLYNLPRHRSINLFLHGYQNYWIET EEYSFEEKLVQDLATPPKKDEEEEEDTEKKQPDPLHQIILYFSRNALTERSKLEDDPLYI AYSAMMAKSCQEEEEEEEEEKEKTFEEKEMEKQRTLYQQARLHDRGAAEMVLQMISASKG HTGPMVVETLKLGIAILNGGNTIVQQKMLDYLKEKKDAGFFQSLSGLMQSCSVLDLNAFE RQNKAEGLGMVTEEGTLIVRERGEKVLQHDEFTRDLFRFLQLLCEGHNNDFQNYLRTQMG NTTTVNIIISTVDYLLRLQESISDFYWYYSGKDVIDESGQRNFSKALAVTKQIFNSLTEY IQGPCIGNQQSLAHSRLWDAVVGFLHVFANMQMKLSQDSAQIELLKELLDLLKDMVVMLL SLLEGNVVNGTIGKQMVDTLVESSSNVELILKFFDMFLKLKDLTNSDAFKEHDPDGKGII SKKEFQKSMEAQKQYIQSEIEFLLSCAEADENDMFNYLDFVERFHEPAKDIGFNVAVLLT NLSEHMPNDSRLQSLLEPAESVLNYFEPYLGRIEIMGGAKKIERVYFEISESSRMQWEKP QVKESKRQFIFDVVNEGGEQEKMELFVNFCEDTIFEMQLASQISETDSAERPEEEEEEES CYVVDIGDDEEEEKSLESPSAFAMACAAVKKNVTNFFKMVTVKNLRKQYRKVRKMTVKEM VKVFFSFFWILFVGMFQLFFTIVWGIFQILWSTVFGGGLVEGAKNIKVTKILGDMPDPTQ FGIHDDVTEAEKAEGAEHGIRAELVQFVKGEKAETDIISDIFGIPTKKEGGSKHGHDAGL GDIAEMLGSDIQSSLENTVRKKKGLQLSEIAKEAEAERKVEAEKADMEDGEKEDKAKEVQ SEQLEEGKVKKKKRRHGQKIEKPEAVMANFFKALEIYQTKMLHYLARNFYNLRFLALFVA FAINFILLFYKVTEEPLDEVEEDSNLWNTFDEEEEEEGMVFFVLEESTGYMAPALRALAV IHTIISFVCVIGYYCLKVPLVVFKREKEVARKLEFDGLYITEQPSEDDIKGQWDRLVINT PSFPNNYWDKFVKRKVINKYGDLYGAERIAELLGLDKNALDFSPVEESEPEEASLLSWLS SIDTKYHIWKLGVVFTDNSFLYLAWYTTMSILGHYNNFFFAAHLLDIAMGFKTLRTILSS VTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYV GVRAGGGIGDEIEDPAGDPYEMYRIVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQ VREDMETKCFICGIGNDYFDTTPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQESF VWKMYQERCWDFFPAGDCFRKQYEDQLG NT seq 14667 nt NT seq  +upstreamnt  +downstreamnt atggctgaagggggtgaaggaggggaagatgaaatacagttcctacgaactgatgacgaa gtagtacttcagtgtgttgccagcgttcacaaagaacaaaggaagttttgcttggcagct gagggacttgggaatcgcctgtgctttttggaaccaacatcagaagctaaatatgttcct ccggacctttgcatctgtaattttgtacttgaacagtccctgtctgtcagagcccttcaa gaaatgctggccaacacaggggataatgccggtgaagggtttataaaaaaggcagctcaa ggtggtcacagaaccctgctatatggtcatgctatactacttcgacattcgttcagtgaa atgtatttgacttgtttaacatcatcaagatcccagacagataaacttgcatttgatgtg ggactgagagaaaatgcagcaggtgaagcatgctggtggacaatacaccctgcatctaaa caaaggtcagaaggagaaaaagttcgaataggtgatgatcttatcctggtcagtgtgtcc tctgaaagatacctgcatctttccatgtcaaatggaagtattcaggtggatgcctccttt atgcagacgctttggaatgtacatcctacatgctcaggaagcagtattacagaagggtat cttcttggtgggcatgtagtacgttttttccatggccatgatgagtgtttgacaattcca tctacagatcagaatgattcacagcaaaagaaagtactttatgaaactggaggagctgga gttcgagcaaggtctttgtggagagtagaaccacttcgaataagttggagtggaagtaac atcaaatggggacaacctttccgtcttcgacatattacaacaggaatgtacttggctctg aatgatgatgaaggacttgtaatgttagacagagaaaagtcagacacaacatcttctgct ttctgttttagagcatcaaaggagctaaaagaaaaacaggattccactcttaaacgtgat attgatggaatgggagtcccagaaataaagtatggtgattcagtctgttttgttcaacat gtggccagtgctttatggttgacttataaagcacaggatgctaaatcagcacgtttaggt cccttgaaaagaaaggttatattgcaccaagaaggccatatggatgatggtctaacctta caaagatgtcaacatgaagaatcccaggctgctcgaatcattcgcaatactacaagctta ttcagccagtttataaggtatggaaacaacagaacactatcacccatcgccctgcctgtt gaggagatggctcagactctgcaagacctgattacttacttccagcctcccgaagaagac ctggaacatgaggataaacaaagcaagcttcgatcactgaaaaacagacagaatctattc aaagaagagggcatgctggcactagttttgaattgcattgatcgtttaaatgactacaac agtgcagctcattttgcagaaattgcaagagaagaaaatggtaccacatggaaagaaatt ttaaatcttctttacaaattgttagctgccctcattcgtggcaacagaaacaattgtact caattttccagtaaccttgattggctaataagtaaattggacagattagaatcttcctca ggtattttggaagtgttgcactgcatcttgattgaaagcccagaagctttaaatataata gctgaggagcatataaaatctattatttcattgttggataaacatgggcgcaattacaag gttctcgatgtgctttgctctctctgtgtctgtaatggagttgcggttcgtgccaatcaa aatttgatctgtgacaatctattgcctagaagagacttactcttgcaaacacgtttgatt aatgatgtgacaagcataaggccgaacatatttctgggtgttgctgagggctctgcacaa tacaagaagtggtactttgaattaataattgatcaggttgatccattcttgacggcagaa cccacccatttacgagttggatgggcctctacttcaggttatgctccctaccctggagga ggagaaggatgggggggcaatggtgttggggatgacctatactcttacggttttgatggc ctccatctgtggtctggtcgagtacccagggctgtagcatctgtcaatcaacatttgttg tcatctgatgatgtggttagctgctgcttggatttaggtgtacccagcatttcattccgc attaatgggcagcctgtacaaggaatgtttgagaacttctgtactgaagggtttttcttc cctgttgtaagcttatcagcaggtgtaaaagctcgtttcttattgggtggacgtcacgga gagtttaaatttctacctcctgctggctatgctccctgctatgaagccttgcttccaaaa gagaagatgaaactggaaccagtgaaagaatacaagagagattctgatggagtgagggat ttgctgggtacaacacaattcctctcccaagcttcctttatcccttgtcctatagacacc agtcagattgctcttccttttcatcttgaaaagatcagggacaaactagctgaaaatatc catgaactgtggggaatgaataaaatagaactgggctggacatatggcaagatacgggat gataataaaaggcatcacccttgtcttgtagaattctcaaaattacccgagacagagaag aattataatctgcaaatgtcaactgaaactctcaaaacccttttggcccttgggtgtcac attgttcatgctaatccagcagcagaggaagatcttaaaaaagtcaagcttcctaaaaat tacatgatgtcaaatggatataaacctgcccctcttgatctttctgaagtgaaattgtta ccttctcaagaattcctagttgacaaactagcagaaaatgcacataatgtctgggcaaaa gacagaataaagcaaggatggacctatggcattcagcaggatctaaagaacaaacgtaat cctcggctagtgccatatgcattattagatgaacgtactaaaaaatcgaacagagatagc ctccgtgaagctgttagaacatttgcaggctatggttatagtgttgagccacctgaccaa gaaatagctgatcaaacaacggaaaaagtcagcattgacaagatacgttttttcagagtc gaacagtcttatgcagtgaagtctggaaagtggtacttcgaatttgaagctgtgacaggt ggagacatgcgtgttggctgggccaggccaggctgtagacctgacatagaactgggagct gatgaccaagcatttgtttttgaaggaagcaaaggccagcgttggcatcaaggcagtgga ttctttggacgaagttggcaaccaggagatgtggttggttgcatgataaacttggatgac aaatccattatctttactttgaatggagaattgcttataaccagtaaaggttcagaactt gcatttgctgactttggaatagaaagtggttttgttccaatttgcgcactgggtctgtct cagattggacgtatgaaccttggaatggatgccagtacattcaagtattatacaatgtgt ggccttcaagaaggttttgaaccttttgcagtaaatatgaaccgagatgttgctatgtgg ttcagtaaacgcttaccaacatttgtcaatgtgccaaaaaatcatcctcacatagagata tggagaattgatggaaccattgagagtccacctcggttaaaagttactcacaaaacgttt ggcacacagaacagcaattcagacatgatatattgtcgtttgagtatgcctattgagttc cgttcatcattcaactttggcatgggtgtggaaaatgcctcatctgatattttccaaaaa cgaaaacacagccaagaaatttctgttccttctactacgtatttttattcgttgcggata tttgctgggcaagacccatcctgtgtctgggttggctgggtaacaccagactatcatttt tacagtgagaattttgacctaaataaaaattgtacagtgacggttactttaggtgatgag agaggcagggttcatgaaagtgtgaagcgcagtaattgctatatggtttggggaggagat ataacttctaattcccagagatcaggtcgtagcaatgttgatttagaaattggatgcttt gttgacctagctactggaatgttgtcattcacagccaatggaaaagagcttggcacttgt tatcaggttgaacccaacacaaaactttttccagcaacttttgtacagcctacaagcact aacttggttcagtttgaacttggtaaattaaagaataccatgcctttatcagcagcaatt tttaaaagtgaggaaagaaatcctattcctcagtgcccccctcgccttgatgtgcaaaca attacacctgttttatggagcaggatgcctaacagctttctcaaagtggaaactgagcgt gtcagtgaacgtcatggatgggttgtgcagtgtttggaacctctgcagatgatggcactt catatcccagaggaaaacagatgtgtcgatattttggaactatgtgaacaagaagatttg atgaagtttcactatcacactttaaaactctatagctcagtttgtgctctaggtaacact agagttgcttatgcactttgtagccatgtggatgtatctcagttattttacacaatagat aatcaatatttacctggactcctacgttctggattctatgacttgttgattagtatacat ttggagcatgccaagcaagccaagctcatgatgaacaatgaatttatcattccagttaca gaggaaactcgaactattagattatatcctgatgaaacaaagaagcatggtttacctgga gtagggcttagcacttgtctgaaaccaagctttcatttttctactccttgctttattgtg accagtgaagaacatcagacatccagcccagagataccccttgatacacttaaatccaaa gccataagtatgctaacagaggcagtacagtgtagtggtactcatatacgagaccctgtt ggaggacacattacattccagtttgttcctgttcttaaactaatagcaacactgctcata atgggggtttttgatgatgatgatgtgaagcaggtgttaatcctcattgatccaaatgta tttggagatcacaaggaagaaacagaagagggtacagaaaaggaagaagttacacaagtt gaagaaaaagctgtagaagctggagaaaaagcaataaaagaaaccaaagctcctacaaca ggcttgttgcagacaagattaccagaatctgttaagcttcagatgtgccatttactcaat tatttctgtgactgtgagctgcaacatagagtggaagcaattgtatcatttgcagaccgt tatgtatcaaaattgcagtataatcagaaatacaggtataatgaactcatgcaagccttg aacatgtctgcagctttgactgccaagaagactaaagaatttcggtctcctccacaagaa cagattaatatgctgctgaattttcaactgggagaggattgtccctgtccagaggagatt cgggatgagctgtacgacttccatgatgatcttctaattcactgtggtattccactagaa gaggaagaagaggaagaggaagattccaccttgactggcaaactccgttcgttaatatac aaaatcaaaggtccaccaaaagcagaaaaagtagagcctagagaagaagaagagaaatca cctactacactgaaggaactcatatcccagactatggtacgctggtctcaggaagatcag attcaagatccagaattagttcggattatgtataccctccttcgtaggcaatatgacagc attggtgagctacttcaagctctgaggaaagcatacaccattagtgctgtctctgtgaag gatacaattaatctgcttgctgcactgggccagattcgctcacttctcagtgtcagaatg ggaaaagaggaggaattgctaatgattaatggattaggggatataatgaacaacaaggtg ttttatcagcatcctaacttaatgagagtcttgggcatgcatgagacagttatggatgtg atggtgaatgtgcttggaggagataagtctcagcagatcgcttttcctaagatggtggca agctgttgtcgattcctgtgctacttctgtcgaattagtcgccaaaaccaaaaagccatg tttgagcatcttagttacttactggaaaacagcagcgttgggctggcatttccttcaatg agaggttcaacaccactagatgttgcagcagcctccgtaatggacaacaatgagcttgca ctagcactggaagagccagatctggataaagttgttacttatttggctggttgtggcctg cagagttgtccagtattgctagctaaaggatatccagacattggatggaatccaatagag ggtgaacgttacctgtcattcttaagatttgcagtttttgttaacagtgaaagtgttgaa gaaaatgcaagtgttgttgtcaagctccttattcgacgaccagagtgctttggaccagac cttagaggagaaggaggaaatggtttactggcagctatgcaagaagctatcagaatctca gagaatccttctcgtgaccttccctcacaaggatataagagagaaggtgatgaggaggag gaagaggaagagattgtgcacatgggcaatgcaatcatgtcattttactcagctctcata gatttacttggacgctgtgcaccagaaatgcatcttattcaaagtggaaaaggtgaagct attcgaatcaggtcaatcctccgatctctagtgccaactgaagatttggttgggattata agtataccgctaaagctgtcaacagttaacaaagatggcacagtaaatgagccagatatg tctgcaaatttctgtcctgatcataaagcaccaatggtactcttcttggaccgtgtatat ggtattaaggaccaaaccttcctccttcacctattggaagttggatttttaccagattta agagcttctgcctctctggatacagtttctctgagtaccacagaggcagctctcgcacta aatagatatatttgttcagctgtgtttccattactcaaaagatgtgctcccctcttttct ggaacagagcatcatgcctctttggttgactccatgcttcacacaatatataggttatcc aagggacgttcccttacaaaagcacaacgagacactattgaagaatgcctgcttgctatt tgccaccacttacgtccctctatgctacaacagctgttgagaaggctagtttttgatgta ccactactcaatgagtactgtaaaatgcctctcaagcttctgacaaatcactatgaacag tgctggaagtattattgtctaccttcaggaatgggaagctatggaattgcagcagaagaa gaattacatttaactgagaaacttttctggggaatatttgattccttgtctcataagttc ctatctctcctgcagaagtacgatccagagctctttcgaatggccttgccttgtctaagt gctatagctggtgccttgcctcctgattatttagatacacgaattagatcaactttggaa aagcagacttcagtggatccagaaggaaattttgatcccaaacctgtcagtacagcaaac cttgtacttcctgaaaagttggagtatattgtcagcaagtatgctgaacattcccatgat aagtgggcctttgataagactaataatggatggaaatacggtgtttcactggatgaaaat acgaagactcacccattaataagacctttcaaaactttaacagaaaaggaaaaagaaatt tatcgttggcctgctagagaatcactgaaaaccatgttggccatgggatggagcctagaa aggaccaaagaaggaggagaaacaatattacatcagcgtgaaaatgaaaagctccgcagc atatctcagtctagccagggaaatggatatagcccagcaccacttgatctctctaatgtg gtgctttctagggagcttcagggaatggttgaggtaatggcagaaaactaccataatata tgggccaaaaagaagaaaatggagttggaaagcaaaggtggaggtagtcatcctttattg gtaccttatgacacattgacagccaaggagaaatcacgggaccgtgaaaaggcacaggag ctgtttaaattccttcaagtgaatggtataatcatatctcggggtctgaatgacatggat ttggatgcttcatccatggaaaagaggtttgcctttaagtttctgaagaaaattttaaaa tatgttgactctgctcaagagttcattgcacatttggaagccattgtaaccagtggaaaa actgaaaaatctccacatgaccaagaaataaaattctttgcgaaagttcttttaccatta gttgatcagtactttacaaatcactgcctgtacttcctgtcttctccaacaaaaacactc agtagcagtggatatgcatcgaataaggaaaaggaaatggtagcaagcctgttctgcaaa ctagctgctcttgttagacataggatctcaatttttggtagtgattctacaacaatggtt aactgcctgcacatcttagctcagtctcttgacactcgaactgttatgaaatcgggatct gagttagttaaagctggattacgtgccttttttgaaaatgcagctgaagatctggaaaaa acttcagaaaatcttaaacttggaaaatttacccattcacgaacacaaatcaagggtgtt tcacagaatatcaattatactacagtagcattgttacctgtcttgacatcaatttttgag catatttcacagtatcagtttggagttgatttacttttgggtgatgtacaggtttcatgt tatagaattctttgtagcctctattcccttgggactgggaagaacatctatgttgaaagg cagcgccctgcacttggtgagtgcttagcatctcttgcagcagccattccagtagcattt cttgaaccttctctcaaccattacaacccattgtctgtcttcaacacaaaaagtgcaaga gaaagagcaattttaggtatgcctgatacagtagaggagatgtgtccagagatcccccag ttggatggactaataaaggaaattaatgatttagcagagtctggagcaaggtatactgaa atgcctcatgtaattgaggttatcttacccatgctatgcaactatttgtcctactggtgg gaacgagggtctgagagtgttcctgaaagtgccgggcctttctgtacgatgataacatct gaacatctaagcatcattctgggaaacattctgaaaatcattaacaacaatctgggaata gatgaagcatcttggatgaagagaattgcagtttatgctcagcctatcatcagcaaagcc agaccagatctgctgaaaactcactttattccaacactggagaagttgaagaagaaagct ataaagattgtgatggaagaggagcaactgaaagcagacagtaaaactgacacccaggaa gctgagctactcattctcgatgaatttgctgttctttgtagagacctctatgccttctat ccaatgttgatacgttatgtagacaacaacagagccaattggctaaagaaaccagatgca gactctgatgaactcttccgaatggtagctgaagtttttatcctgtggtgtaaatcacat aatttcaaaagagaagaacaaaattttgtgattcaaaatgaaatcaacaacttggcattt ttaacaggagataccaaaagcaagatgtctaaacagagtgctcggaggggaatggccatg caagtaaagtctggaggacaagatcaagaaagaaagaaatcaaagcgtagaggggatttg tactccatacaaacatccttgattgtagctgcacttaaaaagatgcttcctattggcttg aatatgtgtactcctggagatcaagagctcatctctttggctaagactagatacagccat agggacactgatgaagaagtcaaagagcatttacgtaacaacttacatttgcaggaaaag tctgatgatccagctgtgaaatggcagttaaatctgtataaagacattttgaaaaatgat gagcctagtgaccctgagaaaaacgtggaacgtgtgcagaggatatcagctgctctctat catctggagcaggttgaacaaccactgagatccaagaaagctgtttggcataaactcctg tcaaaacaacgcaaaagggctgttgttgcttgttttagaatggcaccattgtacaacctg cccaggcaccgttctattaacctcttcctccatggctatcagaactattggatagaaaca gaggaatattcatttgaggagaaactagttcaggatttggctacacctccaaaaaaagat gaagaagaagaggaagatactgagaaaaaacagcctgatccacttcatcagattatcctt tattttagtcgcaatgctctcacagagaggagcaaactagaagatgatcctttatatatc gcctattctgccatgatggcaaagagctgtcaggaagaagaggaggaagaagaggaagaa aaagagaagacatttgaggagaaagaaatggaaaagcagagaacactttaccagcaagct cgcttgcatgatcgtggagctgctgagatggtccttcagatgattagcgcaagcaaaggt catacaggacccatggttgttgaaacattaaaacttggtattgctattctaaatggtggg aataccatagttcaacagaaaatgttagactacctgaaggagaaaaaggatgctggattt tttcaaagtctctctggcttgatgcagtcctgcagtgttcttgacttgaatgcgtttgag agacaaaataaagcagaaggcctgggaatggttactgaagaaggaactctcatcgttcgt gagcgtggtgaaaaagtgttgcagcatgatgaatttactcgagatctatttagattttta caactgctctgtgaagggcataacaatgattttcaaaattacctacgtactcagatgggc aacaccacaacagtgaatattatcattagtactgttgactatctcttgcgtcttcaggaa tcaatcagtgacttttattggtactattcaggaaaagatgtcattgatgaatcaggacaa cgtaacttctctaaagctttggctgtcaccaaacaaatattcaattcccttacagaatat attcagggcccttgcataggtaaccaacaaagtctggctcatagtaggctgtgggatgca gttgttggctttcttcatgtctttgccaatatgcagatgaaactttcacaggactctgct cagattgaattgcttaaagaactgctagatctactaaaggatatggtagtcatgctgttg tcactgcttgaaggtaacgttgtaaacggaacgattggaaaacaaatggtcgatacgctt gtagaatcatctagcaatgtagaattgattttgaaattttttgacatgttcctgaaatta aaagacctaactaactcagatgctttcaaagaacatgacccagatggtaaaggcataatt tcaaagaaggaattccagaagtcaatggaggctcaaaaacaatatatacagtcagagatt gaattcctgctatcctgtgcagaagctgatgaaaatgacatgtttaactatctcgatttt gtggaaagattccacgaaccagccaaagacattggatttaatgtagcagtattgctaaca aacctttcagaacacatgcctaatgattcacgccttcagagcttacttgaacctgcagaa agtgttcttaattattttgaaccataccttggccgtattgaaataatgggtggagccaag aaaatagaaagagtttactttgaaattagtgagtccagtagaatgcagtgggagaagcca caggtgaaggaatccaaaaggcagttcatatttgatgttgtaaatgaaggtggagaacaa gaaaagatggagctctttgtgaatttctgtgaagacacaatctttgaaatgcagttagca tcccagatctctgaaactgattcagctgaaaggcctgaggaagaggaagaagaagagtct tgctatgttgtagatattggagatgatgaggaagaagaaaaatccctggaatctccttca gcttttgcaatggcctgtgctgcagtgaagaagaatgttaccaacttttttaaaatggtt actgtgaagaacctaagaaaacagtacaggaaagttagaaagatgacagtaaaagagatg gtgaaagtgtttttctcctttttctggatcctatttgtagggatgttccaactgttcttt actatagtgtggggaattttccagattctttggagcactgtatttgggggtggcctggtt gaaggagccaaaaacattaaagtcactaaaatattaggggacatgcctgacccaacacag tttggaatccatgatgatgttacagaagcagaaaaagctgaaggtgctgagcatggcatt agagctgaacttgtccagtttgtaaagggcgaaaaggcagaaactgacattatctctgat atttttggcattcctaccaaaaaagaaggtggctcaaaacatggtcatgatgctggactt ggggatattgcagaaatgcttggttctgatatccagtcttctttggaaaacacagttcgt aagaaaaaaggattacagctatctgaaattgcaaaagaagctgaagcagaaagaaaagtg gaagctgagaaggctgacatggaagatggtgagaaagaagataaagcaaaggaagtacag tctgagcagctggaagagggtaaggtgaagaaaaagaagagaaggcatggacaaaaaatt gagaaacctgaggctgttatggctaacttcttcaaagctttggaaatttatcaaacaaaa atgctgcactacctagcaagaaatttttataacttacggtttcttgctctatttgttgca tttgctatcaacttcattctactattttacaaggtgacagaagagccacttgatgaggta gaggaagactctaatctctggaacacttttgatgaagaggaagaggaggaaggcatggtg ttttttgttttagaagaaagtacgggttacatggcacctgctctcagagcattggcagtt atccataccatcatctcctttgtctgtgtgattggatactattgcttaaaggtccctctg gttgtattcaaaagagaaaaggaagtagctaggaagctggaatttgatggattatacata actgaacagccatctgaagatgatattaaaggacaatgggatcgcctggttataaacaca ccgtcctttcctaacaattactgggacaaatttgtaaaacggaaggttattaacaagtat ggagacttatatggagcagagcgcatagcagaacttttgggtttggacaaaaatgccctt gattttagtccagtggaagagagtgaaccagaagaggcgtctcttctatcatggttaagc tccattgatacaaagtaccacatttggaagctcggtgttgttttcactgataattcattt ttatacttagcttggtacacaactatgtctatccttgggcactacaacaacttcttcttt gctgctcatctgctggatattgctatgggtttcaagactttgcgaaccattctgtcttca gtcactcacaatggcaaacagcttgtgctcactgtaggactcctggctgtagtagtgtat ctttacaccgttgtggcgttcaactttttccgcaaattctacaacaaaagtgaagatgaa gatgaaccagacatgaaatgtgatgacatgatgacgtgttacctgttccacatgtatgtg ggtgtaagagctggtggtggcattggggatgaaattgaggatcctgcaggagacccttat gaaatgtatcgaattgtctttgacatcacatttttcttctttgtcattgttatcctactg gccattattcaaggtctgattattgatgcttttggtgaattaagagaccagcaagaacaa gtgagagaagatatggagaccaaatgttttatttgtggaattggcaatgactattttgac acaaccccacatggctttgaaacacatactttgcaagagcacaacttggcaaactacctg ttctttttaatgtatctcataaacaaggatgaaactgagcatactggccaggaatcattt gtgtggaagatgtaccaagaaagatgttgggactttttcccagcaggagactgcttccgg aaacagtatgaggatcaacttggctaa

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