Agrilus planipennis (emerald ash borer): 108744616 Help Entry 108744616         CDS       T07419                                  Name (RefSeq) ryanodine receptor   KO K04962   ryanodine receptor 2 Organism apln  Agrilus planipennis (emerald ash borer) Brite KEGG Orthology (KO) [BR:apln00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:apln04040]     108744616    04990 Domain-containing proteins not elsewhere classified [BR:apln04990]     108744616 Ion channels [BR:apln04040]  Voltage-gated cation channels   Ryanodine receptor    108744616 Domain-containing proteins not elsewhere classified [BR:apln04990]  EF-hand domain-containing proteins   Other EF-hand domain-containing proteins    108744616 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR SPRY Ins145_P3_rec MIR RR_TM4-6 RIH_assoc Ion_trans EF-hand_7 Motif Other DBs NCBI-GeneID:  108744616 NCBI-ProteinID:  XP_025830516 UniProt:  A0A7F5QZ06 LinkDB All DBs Position Unknown AA seq 5123 aa AA seqDB search MAEAEGGSEQDDVSFLRTEDMVCLSCTATGERVCLAAEGFGNRHCFLENIADKNIPPDLS QCVFVIEQALSVRALQELVTAAGSETGKGTGSGHRTLLYGNAILLRHQNSDMYLACLSTS SSNDKLAFDVGLQEHSQGEACWWTVHPASKQRSEGEKVRVGDDLILVSVATERYLHTTKE NEVSIVNASFHVTHWSVQPYGTGMSRMKYVGYVFGGDVLRFFHGGDECLTIPSTWSTEAA HNIVIYEGGSVMSQARSLWRLELARTKWAGGFINWLHPMRIRHLTTGRYLSVNEQNELCL VTREEATTASSAFCLRQEKDDQKIVLEEKDLEVIGAPIIKYGDSTVIVQHSETGLWLSYK SYETKKKGVGKVEEKQAVLHEEGKMDDGLDFSRSQEEESRTARVIRKCSSLFTQFINGLE TLQMNRRHSLFFASVHLNEMVMCLEDLINYFAQPEDDMEHEEKQNKLRALRNRQDLFQEE GILNLILEAIDKINVITSQGFLATLAGDQSWEMISGYLYQLLAAIIKGNHTNCAQFANSN RLNWLFSRLGSQASSEGTGMLDVLHCVLIDSPEALNMLSDEHIKVIISLLEKHGRDPKVL DVLCSLCVGNGVAVRSSQNNICDFLLPGKNLLLQTQLVDLVASIRPNIFVGRVEGSAIYQ KWYFEVTVDHWEQTTHMMPHLRIGWANTKGYIPYPGGGEKWGGNGVGDDLYSFGFDGAFL WTGGRNTKVVDNIIEPFIRKGDVVGCALDLTVPSISFSFNGAPVSGSFRNFNLDGMFFPV ISCSSKLSCRFLLGGDNGRLKYIPPEEFSPLVESLLPQQVLSLDPCFYFGNLNKCVLAGP WLVEDDVAFVPGPVDTSMVTLPNYIESIRDKLAENIHEMWAMNKIEAGWQWGDYRDDLRH IHPCLVPFEKLPAAEKRYDSQLAVQTLKTIIALGYHVTMDKPPSRIKTVRLPNEPFMQAN GYKPAPLDLSAIILTPKMEELVDQLAENTHNLWAKERILQGWTYGLNEDPDMKRSPHLVP YAKVDEAIKKANRDTASETVRTLLVYGYNLDPPTGEQHEAMLAEAARLRQSDFRTYRAEK NYAVSSGKWYFEFEILTAGPMRVGWAKADCAPGNMLGSDENTWAFDGYSMRKVHGGVSEL FGIKYQVGDIIGIFLDEIDHTISFSLNGELLMDALGGETTFADVHGDNFVPACTLNVGQK AKLNFGQDVSTLKFFTTCGLQEGYEPFCVNMKRPVTYWYTKDQPIFENTDDIPDTKIDVT RILAGSDSPPCLKISHNTFETMEKANWEFLRLSLPVICHSEFITEEEKSRRWQEIKIRQH RLRAEANQTTPAHIEQIMKSGFSISDLKGLHRNYSEDAVEADEVMNKPTNKSTKSMPPRP PRKGSLSRNVYEVEQGLEASSGKINRSTSELDLHRYHGLHRNYSEDAVEADEVMNKPTNK STKSMPPRPPRKGSLSRNVYEVEQGLEASSGKINRSTSELDLHRYHDTSLQTNNQEKTDD KKKRGRSPFRFFSRKREASGDRSKERTKGKAKTPEQEHGRRGGLNPHARTVSGMPSPMLA RSPTVRMGSQTDLKIQPPSVPDRQQKQMSVPQTSDVESIGNEVFDSECLKLINEYFYGVR IFPGQDPTHIYIGWVTTQYHLHSKDFNQSQVRKASVILIDNYDRVVDCVDRQACYMVRAD ELYNQVTQDATGKGASQGMFIGCFIDAATGIISFTCEGKETKHRFKMEPNTKLFPAIFVE ATSKEILQIELGRTATTLPLSAAILQNSAKHVTPQFPPRLKVQCLNPHHWARVPNQNLQV HALKLSDIRGWSMLCEDPVSMLALHIPEEDRCMDILELIELEKLLSFHAHTLTLYAALCY QSNYRAAHVLCKHVDQKQLLYAIKSEYMSGPLRQGFYDLLIAIHLESTATTMEVCKNEYV IPLGQELKDLYEEPEMGHSLRRLKVESVIPIMKMSDIGYVARLFTPLLKLVDRLLLVGNL RDEDVEKLLIMIDPETWDPLFEKDGKDEHRKGLLQMKMAEGAKLQMCYLLQHLNDVQLRH RVESIIAFSHDFVGDLQTDQLRRYIEIKQSDLPSAVAAKKTKEFRCPPKEQMNTILGFKN LEEDDKENCPIGEDLCDRLRGFHDGLMSQVSLNALQVPQDAENPDDQQKPNPFKRLYNLI NAVKELEEEPKEEPEPERKMPEEVFRKVLIATVVRWAEEAQIETPKLVREMFSLLVRQYD SVGALIRALQKTYVINAKTKLDVAEMWVGLSQIRTLLPVQMSQEEEELMRERLWKLVNNH TFFQHPDLIRILRIHENVMAVMINTLGRRSQQQAQPAEGETVTKEKDTSHEMVVACCRFL CYFCRTGRQNQKAMFEHFDFLLENSNILLSRPSLRGSTPLDVAYSSLMENTELALALREH YLEKIAIYLSRCGLQSNSELVEKGYPDLGWDPVEGERYLDFLRFCVWVNGESVEENANLV IRLLIRRPECLGPALRGEGEGLLRAIIDANKMSERISDRRKMMEEAEGTVNMPQFSHPLP ESDEDEDYIDTGAAILNFYCTLVDLLGRCAPDASVIALGKNESLRARAILRSLVPLEDLQ GVLSLRFTLQNPAAGEERPKSDMPSGLIPAHKQSVVLFLERVYGIETQELFYKLLEEAFL PDLRAATMLDRNDGSESDMALSMNRYIGNSILPLLIKHSNFYNEAENYAPLLDASLHTVY RLSKNRMLTKGQRECVSDFLVALTSQMQPSMLLKLLRKLTIDVSNLSEYTTVALRLLTLH YERCTRYYGSTTGQGLYGTSSDEEKRLTMMLFSNIFDSLSKMDYDPELFGKALPCLIAIG CALPPDYSLSKNYDDEWYANKSSTTGPNGPYNPQPINTLSIQLNNDLNQIVQKFSEHYHD AWASRKLENSWQYGENWSETNKTHPRLKPYHMLNDYEKERYKEPVRESLKALLAIGWTVE HSEVDVPMSNRSSVRRQSKSGESSSPFNYNPHPVDMTNLTLSREMQNMAERLAENAHDIW AKKKKEELTTCGGGIHPQLVPYDLLTDKEKKKDRERSQEFLKYLQYQGYKLHKPSRERKT DDEQTTVGPSVEFRFAYSLLEKLIQYSDRATVNMKILKPSAIFSRRTSFRTSSRDIKFFS KVVLPLMEKYFSTHRNYFIAVATATNNIGAASLKEKEMVAALFCKLASLLRSRLSAFGAD VRITVRCLQVLVKCIDAKTLVKNCPEFIRTSMLTFFNNTADDLTHTITNLQEGKYSHLRG THLKTSTSLFYINSVVLPVLTAMFDHLANCEYGSDLLLDEVQVASYKILGALYILGTDPN LTHDRKYLKTEMERYKPALGSCLGAFSSTFPVAYLEPHLNKHNQFSLLNRIADHSLEAQD IMARMENIMPTLETVLSEVDQFIESEKTYTDTPHIIDVIMPMLCSYLPFWWSQGPDNVSP TGGNHVTMVTAEHMNQLLKNVLKLIKKNIGNENSPWMTRIAAYTQQIIINSSEELLKDPF LPLAERVKKRTEMLFHKEESLRGFIKSSTDDTSQIEAQIQEDWQLLVRDIYSFYPLLIKY VDQQRMHWLRHNVVEAEHLYHYVADIFNIWSKSQYFLREEQNFISANEIDNMVLIMPTAT RRTAIPDGSQPSVGKVKKKKKHRDKKRDKDKEIQASLMVACLKRLLPVGLNLFAGREQEL VQHCKDRFLKKMPEYDIIDFAKTQLTLPDKIDPADEMSWQHYLYSQLGTKKSIAISTAVD NNGKSQLEETVERIVAMSKVLYGLHMIDHPQQQQKGIHRSVISMQRKRAVLSCFRQASLH SLPRHRAINIYIRSYCELWLQDENTGQEVMIEDLTQSFEDAELNKKEAQEEEGKPDPLTQ LVTTFCRGAMTERSGALQEDPLYMSYAEIIAKSCGEEEEEGEEEGGEGEEGGASIHEQEM EKQKLLFHQARLANRGVAEMVLLHISACKGVPSDMVMMTLQLGISILRGGNSDIQMGMLT HLKEKKDVGFFTSIAGLMNSCSVLDLDAFERNTKAEGLGVGSEGAAGEKNMHDAEFTCAL FRFIQLTCEGHNLEWQNYLRTQAGNTTTVNVVICTVDYLLRLQESIMDFYWHYSSKELID PAGKANFFKAIGVASQVFNTLTEVIQGPCTQNQQALAHSRLWDAVGGFLFLFSHMQDKLS KHSSQVDLLKELLNLQKDMITMMLSMLEGNVVNGTIGKQMVDTLVESASNVELILKYFDM FLKLKDLTSSASFQEIDINNDGWIYPKDFKEKMEQQKSYTPEEIEFLLMCCETNHDGKID YVGFIDRFHEPAKEIGFNLAVLLTNLAEHMPNEPRLARFLETAGSVLNYFQPFLGRIEIL GSSKRIERVYFEIKESNIEQWEKPQIKESKRAFFYSIVTEGGDKEKLEAFINFCEDAIFE MQHASGLMAIEDSGGPGQQRATSYNYMTEDDFDGKSKDPIRRGIQAVKDGIRHGLSALSP SNLKHKFAEMQKMSFLELFVGFFKLIFYAFYYSGYGVSIILGFFFKILMFLMRGPQTEEQ VIEIKEEEKTGPMRVLPALPAASEEPNNQVQAFGLDIAKDENQIKLAPHESPTSTSPSSG EGEGETSTEEGVEGHVESETPETPVTLQDLLGGEAARRAAQEKAEAQAAQQAAMQAIEME QKQEVITEKSAVSQINFGAYGQRAVSFLARNFYNLKYVALVLAFCINFMLLFYKVSTLGG EENGSGNGKESNIIISGEGSGSGGGESSEEEDAVELVHVDEDFYYMEHVMRLAALLHSLV SLCMLIAYYHLKVPLAIFKREKEIARRLEFEGLYIAEQPEDDDLKSHWDKLVISAKSFPV NYWDKFVKKKVRQKYSETYDFESISNLLGMEKTSFMAQDTEEGNNSIFYYIMNIDWRYQI WKGGVTITDNSFLYSLWYFTFSILGNFNLFFFAAHLLDVAVGFKTLRTILQSVTHNGKQL VLTVMLLTIIVYIYTVIAFNFFRKFYVQEEDEEVDKKCHDMLTCFVFHLYKGVRAGGGIG DEIEPPDGDDYEVWRILFDITFFFFVIVILLAIIQGLIIDAFGELRDQLESVKEDMESNC FICGIGKDYFDKVPHGFDTHVQQEHNLANYMFFLMHLINKPDTEYTGQETYVWNMYQQRC WDFFPVGDCFRKQYEDELGGGGG NT seq 15372 nt NT seq  +upstreamnt  +downstreamnt atggccgaagcagagggaggatcagaacaagatgatgtttcatttttacgaacggaagac atggtatgtctttcgtgtactgctacaggagaaagggtttgcttagctgctgaaggattt ggtaatagacattgctttctggaaaatattgctgataagaatatacctccagacttatcc caatgtgtttttgtaatcgagcaagctctgtcagtaagagccctacaggagttagttaca gctgcaggaagtgaaacgggcaagggaacaggctcaggtcatagaacgttgctttatggt aacgcaattctcttgcggcatcaaaatagtgacatgtacttggcttgtttgtccacgagt tcaagtaacgataagttggcctttgacgttggtttacaagagcatagtcaaggggaggca tgctggtggactgtacaccctgctagcaaacaaaggtctgaaggagaaaaggtcagagtg ggtgacgatttaattttggtatctgtagcaacagagagatatttgcacaccactaaagaa aacgaagtatctatcgtaaatgctagtttccacgtgacccattggtcagtccagccctac ggtaccggtatgtctcgtatgaagtatgtaggatacgttttcggtggagatgtgctgcgt tttttccatggtggcgatgaatgtcttacaataccatccacctggtctacagaggcagct cataatattgtcatctacgaaggaggcagcgttatgtctcaagcccgatcattgtggcgc ttagaactggcgaggacaaagtgggcgggtggttttattaattggcttcacccaatgcgt atccgtcacttgaccacaggccgctatttaagtgttaatgaacaaaacgaattgtgcctg gtaactagggaagaggctacgactgcttcatctgctttctgtttgcgacaagaaaaagat gatcagaagattgtgctggaagaaaaggatttggaagtaatcggtgctccgattatcaaa tatggagattccacagtgattgtacaacattcagagaccggattgtggttatcatataaa tcctacgaaacgaagaaaaagggcgtaggtaaagtagaagaaaaacaagcagtgttgcat gaggaaggaaaaatggatgacggattggacttcagtagaagtcaagaagaagagtcaagg acagctcgtgttattcgtaaatgtagttctctgttcacccaatttattaatggcttggag acgttgcagatgaatagacgacattccttgtttttcgccagtgttcacttgaacgaaatg gtaatgtgtttggaagatcttattaattatttcgcccagccagaagatgatatggaacac gaagagaaacaaaacaaactccgtgctctacgtaaccgtcaggacttgtttcaagaagag ggaattttgaatttaattctagaagcaattgataaaataaatgtgataacttcccaagga ttcttggcgaccttggccggtgatcagagttgggaaatgatttctggttacttgtatcaa ttgttagctgctataataaagggaaaccacaccaattgtgcccaatttgccaattctaac agattgaattggttattttcacgtttggggtctcaagcttccagcgaaggcaccggcatg ttagatgtacttcattgtgttctcattgattcaccagaagctctaaatatgttaagtgat gaacatattaaagtgattatatcactattggaaaagcacggaagagacccaaaagtgttg gatgtgctatgttcgctatgcgttggtaatggagtagctgtacgtagttcacagaacaat atctgcgattttcttttgccgggtaaaaatttgctattgcaaacgcaattagtcgatctt gtggcgagcattcgtccgaatatatttgtgggcagagtagaagggagtgccatttaccaa aaatggtacttcgaggtgactgttgaccattgggaacaaactactcatatgatgccccat ttacgaattggttgggccaatacaaaaggttatataccgtatccaggtggaggtgagaaa tggggtggcaatggcgttggcgatgatctatattcgttcggatttgatggagctttcctt tggactggcggtcgaaatactaaagttgttgataatataatagaacctttcattagaaaa ggtgatgtggttgggtgtgcactggatctgactgtaccgtcgatatcattctcatttaat ggggctcctgtcagtggtagtttcagaaattttaatttggatggaatgttttttccagtc atcagttgttcttctaaattaagttgtcggtttttgttgggaggcgataatggtcgctta aagtatattccaccagaagaattttctccccttgtggaaagtctgttaccacaacaagtt cttagtctcgatccatgtttttattttgggaatctaaacaaatgtgtactggcaggcccg tggcttgtagaggacgatgttgcctttgtaccaggccctgtcgatacaagtatggtgaca ttgcctaattatatagaatcaataagggataaactagccgagaatattcacgaaatgtgg gccatgaataaaatcgaggctggctggcaatggggcgattatcgtgatgacttgagacac attcacccttgtcttgtgccttttgagaaactaccagcagctgaaaaaagatacgattca caattggctgtacaaacgttaaagactataattgctctgggttatcacgttactatggat aagcccccgtcacgtatcaagactgtacgtcttcccaatgaaccttttatgcaggcgaat ggttataaacctgctcctttggatttgagtgctattattttgaccccgaaaatggaagaa cttgttgaccagttagccgaaaatacacataatctatgggcaaaagaacgaatattacaa gggtggacttacggcttgaacgaggatcccgatatgaaacgtagtcctcatttggtacct tatgctaaagtagatgaagcaattaagaaagctaacagggacactgcatcagaaactgtg agaaccctacttgtttatggatataatttggatccgcctactggcgagcaacatgaagct atgctagcggaagctgcaagattgcgtcagtcagattttcgaacctaccgcgctgagaag aattacgcagttagctcaggaaaatggtacttcgaatttgagattttaacagctggtccc atgagagtaggatgggccaaagcggactgcgctcctggtaatatgttaggatctgatgaa aacacttgggcatttgatggatacagtatgcgtaaagttcacggtggagttagtgaatta tttggaattaaatatcaagtaggagatattataggcatttttctagacgaaatcgatcac accattagtttctccctaaatggagagttacttatggatgcattggggggcgaaacgaca ttcgctgacgtccacggagacaactttgttcccgcttgtacccttaacgttggtcaaaaa gctaaacttaatttcggacaagatgtttccaccctcaaattctttacaacgtgcggcctt caagagggctatgaacctttctgtgtcaatatgaaacggccggtcacttattggtacacg aaagatcagccaattttcgaaaacacggacgacatacccgatacaaaaattgacgtgact cgaattctggccggttcagacagtccgccgtgcttgaagattagccacaatacgttcgaa acgatggaaaaggccaactgggaatttttaagacttagtttgccagttatttgccattcg gaatttataacagaagaagagaaaagtaggagatggcaagaaataaaaattcgacagcat agattgagagctgaagctaatcaaacaacaccagcacatatagagcaaataatgaaaagt ggattttccattagcgacttaaaaggtttacatcgtaattattctgaagatgctgtggaa gcagacgaagtaatgaataagccgacaaataaatcgacgaagagtatgccacccaggcca cctaggaaaggttccctatcaagaaatgtttacgaagtagaacaaggtctagaggcatca agtggtaagattaatcgatcaaccagtgaactcgatttgcatagatatcatggtttacat cgtaattattctgaagatgctgtggaagcagacgaagtaatgaataagccgacaaataaa tcgacgaagagtatgccacccaggccacctaggaaaggttccctatcaagaaatgtttac gaagtagaacaaggtctagaggcatcaagtggtaagattaatcgatcaaccagtgaactc gatttgcatagatatcatgacacaagtcttcagaccaataatcaagaaaaaacagacgac aagaaaaaacgaggccgttcacctttcagatttttctctcgtaagagggaagcaagtggc gaccgttcaaaagaaagaacaaaaggcaaggcaaaaacgcctgaacaggaacacggtagg cgtggtggtttgaatccgcatgctcgaaccgttagtggaatgccgtctcccatgttagct cgtagccctaccgttaggatgggatcacagacggatcttaaaattcagcccccatctgtc ccagatcgtcaacagaaacaaatgtctgtgccacaaacatcagatgttgaatcgatcgga aatgaagtgtttgattcagaatgtttaaagcttattaacgaatatttctacggtgtacgc atatttcctggtcaagatcctactcatatttacatcggttgggtaaccactcagtaccat ttgcactccaaagatttcaaccaaagtcaagtaaggaaggcctcggttatattaattgat aattatgatcgagttgtggactgtgtcgaccgccaggcatgttacatggttcgagcggat gaattgtacaatcaggtaactcaagatgctacaggaaaaggtgcttcgcagggcatgttt ataggctgctttatagatgctgcaactggtattatatcgtttacttgcgaaggaaaggag actaaacaccgatttaagatggaaccgaatacaaagctatttcctgctatatttgtggag gcaaccagcaaagaaattttacaaattgaactaggtcgaacggccacaacattgcccctt tcagctgccattctgcaaaacagcgctaaacacgtcacaccccaatttcctcccagactc aaggtgcaatgtcttaatccacatcattgggccagagtgccgaatcagaatttacaagtt cacgctcttaaactgtcagatatcagaggttggtcaatgctttgcgaagatcctgtttcg atgttagccttgcacatacctgaagaagacagatgtatggacatactggaactgatcgaa ttggaaaaattgctcagcttccacgctcacactctcactttatatgcagctttgtgttat caaagcaactaccgagctgcgcacgtcttgtgcaaacacgttgaccaaaaacagttattg tacgctatcaaatccgaatatatgagcggacctttacggcaaggattttatgacttattg attgctatccatttggaatctactgcgacgaccatggaggtttgtaagaacgagtatgtt attccactaggacaggaattaaaagatttatatgaagaacctgaaatgggtcatagcttg agaaggctcaaagttgaatcggtaatacctataatgaaaatgagtgatattgggtatgtt gcaagactttttacgccccttttgaagcttgtcgatcggcttttattggtgggaaattta cgcgatgaagacgtcgaaaagttgctgattatgattgatccggaaacgtgggatccttta ttcgaaaaagacggcaaggatgaacatcgtaaagggcttttacaaatgaagatggccgaa ggtgcgaaactgcagatgtgctacttgttacaacatcttaatgatgtacagctcaggcat agggtcgaatctatcattgctttcagtcatgatttcgtgggtgatttacagacagatcaa ctgagaagatacattgaaattaaacaatctgatttgccgtctgcagttgctgctaagaaa actaaggagtttaggtgtcctcccaaagaacaaatgaacacaattttgggctttaaaaac ttggaagaagatgacaaagaaaactgtccgattggagaagatttatgtgatagactaaga ggatttcatgatggtttaatgtcccaagtgtcccttaatgctcttcaggtccctcaagat gctgaaaatcctgatgatcagcaaaaaccgaatcctttcaaacgtttatataatctgatt aatgctgtaaaagaattggaggaagagccaaaagaggaaccagaacctgaacgtaaaatg cctgaggaagtatttagaaaagttttaatagccacagttgttaggtgggctgaagaagct caaattgaaactcccaaactagtacgagaaatgttcagtttattggttcgtcaatatgat tcggttggagcccttatacgagctctccaaaaaacttacgtaataaatgcaaaaaccaaa ctagacgtggctgaaatgtgggtaggactgagccaaattaggaccctgctacctgtacag atgtctcaagaagaagaggaactaatgagggaacggttatggaaacttgtaaataatcac acattctttcaacatcctgatcttattcgtattcttcgcatacacgagaacgttatggct gtaatgatcaacacattaggaagaagatcccagcaacaggcccaacctgctgaaggagaa actgtcacaaaagaaaaggacacttctcatgagatggtagtggcgtgttgtcgattttta tgttatttttgtcgtactggtagacagaatcaaaaagcgatgttcgaacatttcgacttt ttattggaaaatagcaatattttactgtccagacctagtttaaggggatcaacaccttta gatgtggcctactcttctttaatggaaaatactgagttggcattagctctaagagaacat tatttggagaaaattgctatatatttgtcacgatgtggcttgcagtcaaattctgagtta gtagaaaaaggatatccagatttaggttgggatcctgtggaaggagaaagatatctcgat tttcttcgattctgtgtgtgggtcaatggtgaaagtgtagaggaaaatgcaaacctagtc attcgtttattaattcgtagacctgaatgtttgggtccagccttaagaggtgaaggtgaa ggacttttaagggcgattatagatgcaaacaagatgtcagagcgtatttcggatcgcaga aaaatgatggaagaagcagaaggtaccgtaaatatgccacaattttcgcatcctttacca gagagtgatgaagatgaagactacatcgatacaggggcagctattttaaatttctattgc actcttgtcgatcttttgggtcgatgtgctcctgacgcttctgtaattgcgttgggcaaa aatgaatctttaagagctcgtgcaattctgcgatccctcgtaccgctggaagacttacaa ggtgtcttaagtttgaggtttactcttcagaatcctgcagctggggaagagagaccgaaa tccgatatgccctcaggtttaattcctgctcataaacagagcgttgttttatttcttgaa cgcgtatatggcatagaaacccaagagctgttttacaaactattggaagaagcattcttg ccagatctaagggctgcaaccatgttagacagaaatgacggtagcgaatctgatatggct ctcagtatgaatcgctacattggcaattctatattacctcttctaattaaacacagtaac ttttacaacgaagcagaaaattatgcgccgcttttagatgcaagtcttcacactgtttac cgtctatcaaagaaccgcatgcttaccaagggtcaaagagaatgcgtgtctgactttttg gtcgcgcttaccagccaaatgcagccttcaatgttgctaaagttgctccgaaagcttacg atcgacgtttcgaacctatccgaatacacgaccgtagctttaagactattgacattgcat tacgaacgttgcacacgttattatggttcaactaccggtcaagggctttacgggacatcg tcggatgaggagaagcggctgacgatgatgcttttttcgaatattttcgattctttaagt aaaatggattacgatcccgagttgttcggaaaagcactaccgtgtcttattgcaattgga tgtgctctgccaccagattattcgttgtctaaaaactatgacgacgaatggtatgccaat aagagttcaacaacaggacccaatgggccttataatccccagccaatcaatacgttatct attcaactaaataacgacttgaatcaaatcgtacaaaagttttctgaacattaccacgac gcttgggcttcacgtaaacttgaaaatagttggcaatatggtgagaactggtccgaaact aataaaacacatccaagacttaaaccttatcacatgctgaacgattatgaaaaagaaagg tataaggaacctgttcgagaatccttaaaagcccttttagcaatcgggtggacagtggaa cattcagaagtggacgtgcccatgagcaataggagctcggtcagaagacagtcaaaatcg ggagaatcaagttcaccatttaattataacccacatccggttgacatgactaaccttaca ttgtctcgagaaatgcaaaacatggcagaacgtttagctgaaaatgctcatgatatttgg gcaaagaagaaaaaggaagaattgactacatgtggaggaggtattcatcctcaactagtg ccctatgatctgttgactgataaagaaaagaaaaaggacagagaacgatcccaagaattt ttaaaatatttgcaataccaaggatataaattgcataagccttctcgggaacgtaaaact gacgatgagcaaacaactgttggtccttcggttgagttcagatttgcatattcgctattg gaaaagttaattcaatattccgatcgtgcgactgtaaacatgaaaatcttgaaaccctcc gctatctttagccggcggacatctttcaggacatcaagcagagatatcaaattcttctca aaggttgttctgccactgatggaaaaatatttttcgactcatcgaaattattttatagct gttgccacagcgactaataatataggcgccgctagtttgaaagaaaaagaaatggtagcg gcgttattctgtaaactcgccagtcttcttagaagtcggctgtctgccttcggggcagat gtgcgcataactgtgcgttgtctccaagtgttagtcaagtgcatcgatgcgaaaacactg gtcaaaaactgtcccgaatttatcaggacatcgatgttgaccttcttcaataatacggct gacgacttgactcacacaataacaaatttacaagaaggaaaatatagtcacttacgtggt acacatctcaagacttccacttcattattttacataaattcagtggtgttacctgttcta actgctatgttcgatcatttggccaattgcgaatatggaagtgatctcttactcgacgag gttcaggtggcttcatataaaatactgggagcattgtatatattgggtactgatccgaat ttgactcacgatcgaaaatatttgaagactgaaatggagcggtacaagccagcattagga tcttgtttaggagcattcagttccacttttccagttgcttatcttgagcctcacttaaat aaacacaaccaattctctttactcaatagaattgcagatcattcattagaagcacaagac ataatggcgagaatggaaaacataatgccaacattagaaacagttttaagcgaagtagat 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cattatctctacagccagcttggtaccaagaaaagcatcgcgatcagcacggctgtagat aacaatggtaaaagtcaactagaggagacggtggaaaggatagtcgctatgagtaaagtc ttgtatggtttacatatgattgatcatcctcagcaacagcaaaagggcatacaccgcagt gttatatcaatgcaaagaaaacgtgctgtactttcatgcttcagacaggcgtcgttgcat agtttgccgagacatcgagctataaatatctatattcgttcttactgtgaattgtggttg caagatgaaaatacaggtcaagaagtgatgattgaagatctcactcagagctttgaagac gctgaacttaataagaaagaggcacaagaagaggaaggaaaacctgaccctttgactcag ttagttacaacgttctgtaggggtgccatgactgaaagatctggggcattacaggaagat cctttgtacatgagttacgcagagataattgcaaaatcatgtggcgaagaggaggaagaa ggtgaagaagaaggaggtgaaggagaagaaggcggggcatctatacatgaacaagaaatg gaaaagcagaaactattattccaccaagcccgattagccaacagaggcgtcgctgaaatg gttctgctacatatatcagcatgcaagggggtaccatcggacatggtaatgatgaccttg cagttgggtatttcgatattgcgcggtggcaactcagacatccagatgggtatgcttact catctaaaagaaaagaaagatgtcggcttctttacaagcatagcaggtttgatgaatagt tgcagcgtactagaccttgacgcctttgaaagaaatactaaagctgaaggcctaggtgtc ggatctgaaggtgccgccggtgaaaagaacatgcatgacgccgaatttacatgtgctcta 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tgggagaagcctcaaattaaagaatcaaaacgtgcattcttttattctatagttacagaa ggcggagacaaggagaaattagaagcatttattaacttctgcgaagatgcaatttttgaa atgcaacacgccagtggactcatggcaattgaagattctggagggccaggacaacagcga gctaccagttataattatatgaccgaagacgacttcgacggaaaatcgaaagatccaatt cgaagaggcattcaagcagtaaaagacggtataaggcatggattatcagccttgagccca tcaaacctaaaacacaagtttgcggagatgcaaaaaatgtccttccttgaacttttcgtc ggttttttcaaattgatcttctacgcgttttattactccggttatggcgtttctatcatt ttagggttcttcttcaagattctaatgtttttgatgcggggtccgcaaacggaagaacaa gtaattgaaattaaggaagaagagaaaacgggaccgatgcgggtgttacctgctttaccg gcagcttctgaagaacctaacaaccaggtgcaagcatttggattagatatagcaaaagat gaaaaccaaataaaattggctccacacgagtctccgactagtacatcaccatcttcaggt gaaggtgagggtgaaacaagtactgaagaaggcgtagaaggtcacgtagaatctgaaaca cctgaaactccggttactttacaagatttgttaggtggtgaagcagctagaagagcagct caggaaaaagccgaagcccaagccgcccaacaagccgccatgcaagctatcgagatggag caaaagcaagaagtaataacagaaaaatccgctgtctctcaaattaattttggcgcctat ggtcagagagcagtttcattccttgccagaaacttttacaacttgaaatacgttgctctc 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gatgaaattgaaccaccggacggtgacgactatgaagtttggcgtatcctatttgatatc actttctttttctttgttatcgtcattttactggctattattcaaggtttgatcattgat gcctttggtgagcttcgtgatcaactggaaagcgtaaaggaagatatggaatcgaactgt tttatttgtggcataggaaaagattattttgataaagttccccatggatttgatacacat gtacaacaagagcacaatttggcgaattatatgttcttccttatgcacttaattaataaa ccggatacggaatataccggtcaagaaacttacgtttggaatatgtaccaacaacgttgt tgggacttcttccctgtaggagattgcttccgtaaacaatacgaagatgaactaggcgga ggaggtggttaa

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