Archaeoglobus profundus: Arcpr_0743
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Entry
Arcpr_0743 CDS
T01152
Name
(GenBank) isopropylmalate/citramalate/homocitratesynthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
apo
Archaeoglobus profundus
Pathway
apo00290
Valine, leucine and isoleucine biosynthesis
apo00620
Pyruvate metabolism
apo01100
Metabolic pathways
apo01110
Biosynthesis of secondary metabolites
apo01210
2-Oxocarboxylic acid metabolism
apo01230
Biosynthesis of amino acids
Module
apo_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
apo00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
Arcpr_0743
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Arcpr_0743
Enzymes [BR:
apo01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
Arcpr_0743
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Paralog
Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
Motif
Other DBs
NCBI-ProteinID:
ADB57807
UniProt:
D2RHN2
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All DBs
Position
635460..636956
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AA seq
498 aa
AA seq
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MRTIKVFDTTLRDGEQMPGVSLPVNYKIQIAKQLDKLGVDVIEAGFPSASKGEFEAVKEI
ANLGLNAKICGLARVVKKDIDQAIKADVDIVHVFIPTSKIQVEHTIKKTPDEIVQLSVDA
VEYVKSHGVECMFSAMDATRTEMDFLKRIYKAVEEAGVDIINVPDTVGIATPFRFYDMIK
KLKEHLNVPIDVHCHNDFGLATANTYAAVLAGADEVQVTVNGLGERAGNAPLEEVVALLY
AEGFKTNIRMEYLVETSRLVERLTGVKMPPNKPIVGENAFSHESGIHAHGVLKDARTFEP
GIITPEMVGHKRRIVVGKHAGRHQIKKILEDAGYVVDDEKLSIIVQKVKELGDKGKKVTD
LDLFAIAESVLGEVSEKDRIINVDEVTVLTGNKITPTAVINAEVEGERKVTSAIGVGPVD
ATFKAVTELLGRKIKITEFRLDAITGGSDALANVYVTVEDEDGETFTARSAGADIVMASF
DAVIKAVNYLMLKKKRKK
NT seq
1497 nt
NT seq
+upstream
nt +downstream
nt
atgaggacgatcaaggttttcgatacgacacttagagatggagaacagatgcccggtgta
tcattacctgtcaattacaagattcagattgccaaacagctggataagctaggtgtagat
gttatagaggccggttttccttccgcatcgaagggggagtttgaagctgttaaggagatc
gcaaacttgggtttaaatgcaaagatatgcggtttggccagagttgtcaagaaagatatt
gatcaggctatcaaggctgatgtagatatcgttcacgtcttcattccaacttcaaaaatt
caggttgagcacacaattaaaaagactccagacgaaatcgttcaactgtcggtcgatgct
gtagaatacgtcaaatctcacggcgttgaatgcatgttctccgcgatggatgctacgaga
actgaaatggactttctgaagaggatttacaaggctgtcgaagaagctggcgtagatata
ataaatgtgccagatactgtgggaatagcaactccattcaggttctacgacatgatcaaa
aagcttaaagaacatctcaacgttcctatagatgttcactgtcacaacgactttggattg
gccacagcaaacacgtatgcagcagttctagctggagcggatgaagtccaagttacagtg
aatggattgggtgagagggccggaaacgctcctcttgaggaggttgtggcattattgtat
gccgagggtttcaagacaaacataaggatggaatacctagttgagacatctcgcttagtt
gagaggcttacaggagtcaagatgccaccgaacaagccgattgtcggcgaaaacgccttc
agtcatgagagtggtattcatgctcacggagtgcttaaggatgcaagaactttcgagcca
ggaattataacgcctgagatggtcgggcataaacgtaggatagtcgttggaaaacatgcg
ggtaggcatcagatcaagaagattttagaggatgctggctatgttgtggatgacgaaaaa
cttagcataatcgttcaaaaggttaaggagcttggggacaagggtaagaaggttacagac
ttggacttgtttgcgatagcagaatcggtattgggtgaagtgagtgaaaaggataggatc
ataaatgttgacgaggttacggttctaactggaaacaagattactcctacagctgtaata
aatgctgaagttgaaggtgaaaggaaggttacatctgcgattggtgtcggacctgtggat
gcaacgtttaaagctgtaacagagcttctgggaaggaagattaagattaccgagttcagg
ttggatgctataactggaggtagcgatgctctggcaaatgtctacgtcactgttgaggac
gaggatggcgagacctttactgcgaggagtgctggtgcggacatagtcatggcatctttc
gatgctgttataaaggctgtaaactaccttatgcttaagaagaagaggaagaagtaa
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