Actinosynnema pretiosum: CNX65_16270
Help
Entry
CNX65_16270 CDS
T05092
Name
(GenBank) polyketide synthase
KO
K16029
ansamitocin polyketide synthase A
Organism
apre
Actinosynnema pretiosum
Pathway
apre01051
Biosynthesis of ansamycins
apre01052
Type I polyketide structures
Brite
KEGG Orthology (KO) [BR:
apre00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01052 Type I polyketide structures
CNX65_16270
01051 Biosynthesis of ansamycins
CNX65_16270
09180 Brite Hierarchies
09181 Protein families: metabolism
01008 Polyketide biosynthesis proteins [BR:
apre01008
]
CNX65_16270
Polyketide biosynthesis proteins [BR:
apre01008
]
Polyketide synthase (PKS)
Modular type I PKS
cis-AT PKS
Ansamitocin PKS
CNX65_16270
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ketoacyl-synt
Acyl_transf_1
KR
Ketoacyl-synt_C
AMP-binding
PKS_DH_N
PS-DH
PP-binding
KAsynt_C_assoc
AMP-binding_C
ADH_zinc_N_2
RhiE-like_linker
Thiolase_N
adh_short
CurL-like_PKS_C
ADH_N
ADH_zinc_N
Epimerase
AMP-binding_C_3
DUF7080
Motif
Other DBs
NCBI-ProteinID:
ATE54648
UniProt:
A0A290Z6M4
LinkDB
All DBs
Position
3790894..3804948
Genome browser
AA seq
4684 aa
AA seq
DB search
MLRSDLIRPLPELLREHAAERGDRVAFRDARRAVTWVDLELRTRRLAGHLAARRLLPGDR
AVILLGNRVETVECYLALVRAGAVGVPLNPVSTDAELGALLDDSGARLVLTDAAHADQLA
GLRATRPALEVVHVDRDYEALAGVDAPLPAHDALELDDLAWMLYTSGTTGAPKGVLSTQR
NCLWSVAACYAPVLGLTPDDRVLWPLPLFHSLSHIAGVLATTAVGATTRVVDGRSPQDVL
AALHEERSTVLAGVPTTYHHLVRAAGERGFLAPDLRVGLVGGAITTAELRAAVEQRFGVP
LIDAYGSTETCGSITVNWPTGPRVEGSSGLPVPGLAVRLVDPDTGLDAPTGAEGEVWVRG
PSVMVGYHNRPEATAAALRDGWYRTGDLATRDESGFHAVTGRIDDVVVRGGEKVHPAEVE
AVLRAVPGVADAAVVGRPHDVLGEVPVAFLVPGEGFDPAQVLAVCRERLSYHKVPEELYQ
IESVPRTASGKITRRVLLDTPARLRASGERGALFRTDWVPLAAAPGGATAPGAVAGSGAA
TASSAVTGAGAATGPARATTPAAATAPATTPAEASTPVAAARPGGHPVAVMAEPTAPAPG
GAPVVLDLRGDDAPALSGRPDLVLTRGAVAVDGGPVRLGQLAAWTAACRAGITAVDADDD
GAVDPVGLLAAGEPRLLVRSGVVLVPRLHEVPGSVVGRGALDPRRAVAVTGADSGTAAAL
ARHLRGAHGVRDLLLITAPHGRARAGALRDDLVASGARVVLAVAGPDALDRALSRAPSPL
GALVHTGDGDPEALPRLLGARVELVVCATAFDSAAAEDVVLRRRAAGMPARCLAWGPWEA
ETAQARPGLAVLPLRDGLAAFDAALGADEPVVSVLRPDPDLVAGDVPAPLRDLLHVVAAE
PEPVRVAELRASLAGRGERERRRRLLDLVRAETAALRPAEFLVDGHERGFAELGFTSATS
VALRNRLTAATGLALPATAAFEHPTPTALAALLHDELFGASRTPVAPARAVERPVERSGE
PIAVVAAGCRLPGGVASPEDLWEVVRSGADVVSPFPVDRGWDLDALRGACAGGGFLADAA
LFDAALFGVHPREALAMDPQQRLLLEVAWEVFERAGIDPRSVAGDGTGVFAGLMGHDYGS
RPGLDRQLVEGYLSTGNAGSVASGRIAYAFGLTGPALTVDTACSSSLVAVHLAVQSLRRG
ECSMALAGGATVMATPADFVEFARQGALAPDGRCKPFSASADGTAWSEGAGLVLLERLSD
ARRNGRRVLAVIRGSAVNSDGASNGLTAPSGAAQQRVIRAALADAGLSTSDVDAVEAHGT
GTRLGDPIEARALVATYGRDRDGEPLWLGSLKSNFGHPQGAAGIAGLIKLVQALRHGVLP
RTLHVDAPTPEVDWDGVEVLAEQRAWPEVDRPRRAAVSSFGVSGTNAHVVLEQAPAETAA
PAAPERGPVPLPVSAVDAAALRAQARRLADFLAPSDVTAAELAGALRAGRADLGERAVVV
AADRAGALAALEALAADEPSPALVTGRADVTGRTVLVFPGQGGQWVGMGARLLDESPVFA
ERVGECAAAVDPLVDFRVVDVLRGGDLSRVDVVQPVAFVVMVALARLWRSVGVEPDAVVG
HSQGEIAAACVAGALSLADAARVVVLRSRAIAAGLNGGGMASIPLPQAQVEELVAGTGVC
VAAVNGPGSVVVSGEVDALVARVEGARRLPVDYASHSPAVDVLREGLLADLAPITPRPAA
IPMLSTVTGKWLDGAELDADYWFANLRHPVRFADATALLVADGFRAFVEVGAHPVLTAPV
QDLLAGAGPSVATGTLRRDDGGLDRFLRSAAELHVRGVPVDLSPLAPPPVRALDLPTYPF
QRARYWLDADPTAASALRHPLLTSATDLAGGEDLVCQARLSTARHPWLADHAVRGSAVLP
GTCWAELAIRAGDEVGAPALDELLVEAPLVLPERGAVEVQLRIGAPDAAGRRPLEAHARA
EGGAWTRHASGSLAADRSTPVPLTEWPPTGAREVDLAGFYDSRAAEGYDYGPALRGLRRA
WTRDGEVFAEVELPAPLSPDGWGLHPALFDAALHATGLLPPARVAADEVLLPFSWRGTRL
RATGATALRVRLTGTADDHVLRAYDPEGAPVVEVDALRLRPAPATALVGSGALFRVEWVD
LDLPVSTPDSTPGAPVLDRPVLDLPGGDARTLVGLTLEALREHDELTVVTRGAAEDPAAA
AVWGLLRTAQTERPGRFAVVDLDDDPASRALLPALPATGEPQVRVRAGRASAPRLARTRD
DGLPLPAAPTWRLTCDGGTFTDLAATPSPAANRPLEPGEVRVGVRAAGVNFRDAAVVLNA
VPGQRGLGGEAAGVVLETGPGVTGLAVGDRVLGTFDRDFGAFGPVAVTDARLLAPVPPGW
GFARAASVPVAFLTALYGLRDLAQVGPGDRVLVHAGAGGVGGAAVRLAALLGAEVFATAS
PAKWPVLRALGLDDAHLASSRDTGFAERFPNVDVVLNSLTGELVDASLRLLAPGGRFLEL
GKVDVRDLVRADVTYRAYDLRDAGPDRTAELLAEVLGLFAAGRLEPLPLTVRDVRHAPEA
LRHVASGGHVGKVVLTVPRPLDPEGTVLVHGGGALGALTARHLVSAHGARHLLITSRRGP
DAPGAAELAADLAELGATTRFERCDAADRDRVAALLADLGGRPLTAVVHTAGALDDALLA
DQDAARVDAVLRPKLDGALLLDELTRDADLAAFVLFSSAAGTLGNAGQANYAAANAALDA
LAARRRSAGLPATSIAWGHWEHTSALTAGLTAADLARGARHGAGSLTTTEALALLDAALA
SPEPAVLAAALDPRRAAEVPPLLRDLAGPRRAVAAQAVAGADRPLIDVVRAHTATVLGHR
DASAVDANRAFKELGVDSLTAVELRNRLAAATGLALAATSVFDHPTPALLTAHLLAELGH
APAAGTTAPPATAAVTADAGEPIAIVSMACRFPGDVSSPEDLWDLVAGGGDALTPFPADR
GWDLAALFAPDPDRAGRSHAREGGFLADVAGFDADLFGISPREAIGTDPQQRLLLEVAWE
LFERAGIAPDSLRGTDTGVFAGVIAHGYPVLPAHSDQGLEGHRVTGVSGSVVSGRVAYAF
GLQGPAMTVDTACSSSLVGVHLAVRALRGGECSLALAGGVTVLSTPDLFVDFSRQRGLAA
DGRCKAFGAGADGTGFGEGVGLVLLERLWDARRNGRRVLGLVRGSAVNSDGASNGLTAPS
GPAQERVIGRALADAGLSAADVDLVEAHGTGTRLGDPIEARALVATYGRDRGGEPVWLGS
VKSNIGHTQAAAGVAGLIKAVQALRHGVLPATLHAAEPTPEVEWDGVAVLAEQRDWPEVG
RPRRAAVSSFGVSGTNAHVVLEQAPEELSPEGRIPEVRIPDRRTSEGRVPEGRAPEGRTS
GGRAPEGQTSEGRAFGGRVPEDQTSEDRTSEGQASMGRAPEGQAPLGQVSESRAPDHRVP
AGPDRDVPGHLPLVLSAHDPAALRATAARLLPVAERVPLPDLALSLVTGRAALPCRAVIP
ARDRGQALAALRDLASGATAPAERDGGGVAFLLSGQGSQRAGTGRLLERRFPVFRDALRE
VCALLDRRVVGGPGVRAALDDPGLLADTRYAQAGLFAVQVALVRLLDALGVRPDLLAGHS
VGEIAVAHAAGVLSLEDASTLVAARGALMRELPPGVMVAVRAGEDEARAALVDGVELAAV
NGPRATVLTGDEAAVTEVAARLGRATRLRVAHAFHSAAVDAVLPAFADVLARLDFRPPRV
PVATTAPGALDAPEYWLGQAREPVRFADAVTDLHRRGATAFVEVGPGGGLAAAAQECLDG
HDVLCAPLLHRDRDEDHSLITALGALHARGARVDFAPLLADAGGRTTDLPTYPFQRRRFW
LDPAPPTTDAAPLEHPLLTGELEIPGSDTAAFTGRAATGAHPWLADHRLLDAVVVPGTAL
LDLVRAAGRQLGLPEVAELVNEVPLVLGDGAALLRVTAAAPGPDGRREVAVHSRPESAGP
RSPWTRHVTGQLAPESGPLAFDLAQWPPPGALPLPVADHRAAMAATGHGYGPAFLGLRAA
WKLDDEVLVEAVLPDEVADDGHAVHPALLDAVLQAIALTGVEDGSQVRVPFSWRSARGAG
RAGRAVRASLRPDGDGGVRVRVACPRGRPLLEIASLVSRPVTPDRLRPGVLLRQAWTEVG
PPPGAAEPVPLREVGERVPPVVRVDAGHVRDLLPLLQEVVTEPRWESTRLLVTTSGAVGP
RAGRAEGAAVWGLVRSAAAEHPGRFVLADLDDRPESAALLPALATGALPEAVLRAGRVLV
PGLHRVSAPGAGGAVLDPGGAALITGGSGALAALLAEHLVRAHGVRCLVLLSRSGRGPDV
PGADVRHVRGDVANRADVVAALAAVPPDRPLTLVAHLAGVLDDGALTALTPERLDAVLRP
KAEGARHLDELTRDRDLAAFVLFSSVAGALGHAGQANYAAANAHLDGLAHERHALGLPAT
ALAWGPWTEGMARGRGTLSPQVALGLFDAALRTGLPALVPLDREPERRVPAPRAATPAPA
GPSLADRLRPMPPAERRAHLLELVTAEALGVLGHDDGAALPAGQAFRDAGFDSITAMALR
NRLVRLAGVRLPASVVFDHPTPAATAERLEAELFPADRLPGPRHGDDFDDMAADELVRRA
LGGE
NT seq
14055 nt
NT seq
+upstream
nt +downstream
nt
atgctgcgaagcgacctgatccgtcccctgcccgaactgctgcgcgagcacgcggccgag
cgcggcgaccgcgtcgccttccgcgacgcgcgccgcgccgtcacctgggtcgacctggag
ctgcgcacgcgcaggctggccgggcacctggccgcgcgcaggctgctgcccggcgaccgc
gccgtgatcctgctgggcaaccgggtggagaccgtcgagtgctacctggcgctggtgcgg
gcgggcgcggtgggcgtgccgctgaacccggtgtccaccgacgccgagctgggcgccctc
ctcgacgacagcggcgcccggctcgtcctcaccgacgccgcgcacgccgaccagctcgcc
gggctccgcgccacccggcccgcgctggaggtcgtgcacgtcgaccgggactacgaggcg
ctcgcgggcgtcgacgccccgctgcccgcgcacgacgcgctggagctggacgacctggcg
tggatgctctacacctccggcaccaccggcgcccccaagggcgtgctgtccacccagcgc
aactgcctgtggtcggtggccgcctgctacgcgcccgtgctcggtctgaccccggacgac
cgggtgctgtggccgctgccgctgttccacagcctgtcgcacatcgccggggtgctggcc
accaccgccgtcggcgccaccacccgcgtggtcgacgggcgctccccgcaggacgtgctg
gccgcgctgcacgaggagcgctccacggtgctcgcgggcgtgcccacgacctaccaccac
ctggtgcgcgcggccggtgagcgcgggtttctcgcgcccgacctgcgggtcgggctggtc
ggcggcgcgatcaccacggccgagctgcgggccgccgtcgagcagcggttcggcgtgccg
ctcatcgacgcctacggcagcaccgagacgtgcgggtcgatcaccgtgaactggccgacc
gggcccagggtcgagggctccagcggcctcccggtgccgggtctggcggtgcggctggtc
gacccggacaccggcctggacgcgccgaccggcgcggagggcgaggtgtgggtgcgcggg
ccgagcgtcatggtcggctaccacaaccggcccgaggcgacggccgccgcgctgcgcgac
ggctggtaccgcaccggcgacctggcgaccagggacgagtccgggttccacgcggtcacc
gggcgcatcgacgacgtcgtggtccgcggcggcgagaaggtgcacccggcggaggtggag
gcggtgctgcgggccgtgccgggcgtcgcggacgccgccgtggtgggcaggccgcacgac
gtgctgggcgaggtcccggtggcgttcctggtgccgggggaggggttcgacccggcgcag
gtgctggcggtgtgccgggagcggctgtcgtaccacaaggtgcccgaggagctgtaccag
atcgagtccgtgccgcgcacggcctccgggaagatcacccggagggtgctgctggacacg
ccggcgcggttgcgggcgagcggtgagcggggggcgctgttccgcaccgactgggtgccg
ctggccgcagcgcccggtggcgcgaccgcgcccggtgcggtggccgggtctggtgccgcg
accgcgtccagtgctgtgaccggtgccggtgccgcgaccggtcctgcccgtgcgaccacg
cccgctgctgcgacagcgcccgcgaccacgcccgccgaggcgtcgaccccggtggcggcc
gcacggccgggcgggcatccggtggccgtcatggcggagcccaccgccccggctcccggt
ggcgcgccggtggtgctcgacctgcgcggcgacgacgcgcccgcgctgtccggtcgtccc
gacctggtgctcacccgaggtgcggtggccgtggacggcgggccggtgcggctcgggcag
ctcgccgcgtggaccgccgcctgccgcgccgggatcaccgcggtcgacgccgacgacgac
ggcgcggtcgacccggtcgggctgctcgccgccggtgagccccggctgctcgtgcgctcc
ggggtcgtgctcgtgccgcgcctgcacgaggtccccggctccgtcgtcgggcgcggcgcg
ctcgacccccgccgggccgtcgccgtcaccggggcggacagcgggaccgccgcggcgctg
gcccggcacctgcgcggcgcgcacggcgtgcgcgacctgctgctgatcaccgctccccac
gggcgagcccgcgcgggcgcgctgcgcgacgacctcgtggcctcgggcgcgcgggtcgtg
ctcgccgtcgccggaccggacgcgctcgaccgcgcgctcagccgggcgccgtccccgctg
ggcgcgctcgtgcacaccggcgacggggacccggaggccctgccccgcctgctcggcgcg
cgggtcgagctggtggtgtgcgcgaccgcgttcgactcggccgccgcggaggacgtcgtg
ctgcgccgccgcgccgccgggatgcccgcgcggtgcctggcctggggaccgtgggaggcc
gagaccgcgcaggcccggccggggctggccgtgctgccgctgcgggacgggctggccgcg
ttcgacgccgcgctcggcgccgacgagccggtcgtctcggtgctgcgccccgaccccgac
ctggtcgccggggacgtgcccgcgccgctgcgcgacctgctgcacgtggtcgccgccgaa
cccgagccggtccgggtggccgagctgcgggcgagcctggccggtcgcggggagcgggag
cgcaggcggcggctgctcgacctggtgcgcgccgagaccgcggccctgcggcccgccgag
ttcctggtcgacgggcacgagcgcggcttcgccgaactcggcttcacctccgccacctcg
gtcgccctgcgcaaccggctcaccgccgcgaccgggctcgcgctgcccgcgaccgccgcg
ttcgagcaccccaccccgaccgcgctcgccgccctgctgcacgacgagctgttcggcgcg
tcgcggaccccggtcgcgcccgcgcgcgccgtcgagcgccccgtcgagcgctcgggagag
ccgatcgcggtcgtcgccgccgggtgcaggctgcccggcggcgtcgcctcccccgaggac
ctgtgggaggtcgtgcgctccggcgcggacgtggtgtcgccgttcccggtcgaccggggc
tgggacctggacgcgctgcgcggcgcctgcgcgggcggcgggttcctggccgacgccgcc
ctgttcgacgccgccctgttcggggtgcacccgcgcgaggcactcgcgatggacccgcag
cagcggctgctgctcgaagtcgcgtgggaggtgttcgagcgcgccgggatcgacccgcgc
tcggtggcgggcgacgggaccggcgtgttcgccgggctgatgggccacgactacgggtcg
cggccggggctggaccggcagctcgtggagggctacctgagcaccggcaacgcgggcagc
gtcgcctccgggcggatcgcctacgcgttcgggctcaccgggcccgcgctcaccgtggac
accgcctgctcgtcgtcgctggtggcggtgcacctggccgtgcagtcgctgcggcgcggc
gagtgctcgatggcgctggcgggcggcgcgacggtcatggccacgcccgccgacttcgtc
gagttcgcccggcagggcgcgctggccccggacggccgctgcaagccgttctcggcgtcg
gcggacgggacggcgtggtccgagggcgcggggttggtgctgctggagcggctgtcggac
gcgcggcgcaacgggcgtcgggtgctggcggtgatccggggcagcgcggtgaactcggac
ggggcgtcgaacgggttgacggcgccgagcggtgcggcgcagcagcgggtgatccgggcg
gcgctcgcggacgccggtctgtccacttcggacgtggacgcggtggaggcgcacgggacc
gggacgcggctcggtgatccgatcgaggcccgcgcgctggtcgcgacctacgggcgggac
cgggacggcgagccgctgtggctcggctcgctgaagtcgaacttcgggcatccccagggc
gcggccgggatcgccgggctcatcaagctcgtgcaggcgctgcggcacggggtgctgccg
cgcaccctgcacgtggacgcgcccacccccgaggtcgactgggacggggtggaggtgctg
gccgagcagcgcgcgtggcccgaggtggaccggccgcgtcgcgcggcggtgtcctcgttc
ggggtcagcggcaccaacgcgcacgtggtcctggagcaggcgcccgccgagaccgccgcg
cccgccgcgcccgagcgcgggcccgtgccgctgccggtgtccgccgtcgacgcggcggcg
ctgcgcgcccaggcccggcggctggccgacttcctcgccccctccgacgtcacggccgcc
gagctggcgggcgcgctgagagccggccgggccgacctcggcgagcgcgccgtcgtggtc
gccgccgaccgggcgggcgcgctcgccgcgctggaggcgctggccgccgacgagccctcg
cccgccctggtcaccgggcgcgcggacgtcaccggccgcacggtgctcgtgttccccggc
cagggcggccagtgggtgggcatgggcgcccggctgctcgacgagtccccggtgttcgcc
gagcgggtgggcgagtgcgcggcggccgtcgaccccctggtggacttccgcgtggtcgac
gtgctgcgcggcggcgacctgagccgggtggacgtcgtccagccggtcgcgttcgtcgtc
atggtcgcgctggcccggctgtggcgctcggtcggcgtcgagcccgacgcggtggtcggc
cactcgcagggcgagatcgccgccgcctgcgtcgcgggagcgctctcactggccgacgcg
gcccgcgtggtcgtgctgcgcagccgggccatcgccgccgggctgaatggcggcggcatg
gcctcgatcccgctgccgcaggcccaggtcgaggagctggtcgcgggcaccggggtgtgc
gtcgcggcggtcaacggacccggttcggtggtcgtctccggcgaggtcgacgcgctggtc
gcccgcgtggagggcgcccgcaggctgccggtggactacgcctcgcactcgcccgccgtg
gacgtgctgcgcgagggcctgctcgccgacctcgcgccgatcaccccccgaccggccgcc
atcccgatgctgtccaccgtcacggggaagtggctggacggcgccgagctcgacgccgac
tactggttcgccaacctgcgccaccccgtccgcttcgccgacgccaccgcgctcctggtc
gccgacgggttccgggcgttcgtggaggtcggcgcccacccggtgctcaccgcgcccgtc
caggacctgctcgcgggcgcgggcccctcggtcgccaccggcaccctgcgccgcgacgac
ggcggcctcgaccggttcctgcgctccgccgccgagctgcacgtgcgcggcgtgcccgtc
gacctctccccgctggcgcccccgccggtccgggcgctcgacctgcccacctacccgttc
cagcgcgcccgctactggctggacgccgaccccaccgccgcctccgcgctgcggcacccg
ctgctcacctccgccaccgacctcgcgggtggcgaggacctggtgtgccaggcgcggctg
agcaccgcgcggcacccgtggctcgccgaccacgcggtgcgcgggtccgccgtcctgccc
ggcacgtgctgggcggagctggccatccgcgccggcgacgaggtcggcgcgcccgcgctg
gacgagctgctcgtggaggcaccgctggtgctgcccgagcgcggcgcggtggaggtgcag
ctcaggatcggcgccccggacgccgccgggcgcaggccgctggaggcccacgcccgcgcc
gagggcggcgcgtggacccggcacgccagcggctccctcgccgccgaccgctccaccccg
gtcccgctgaccgagtggccgccgaccggcgcgcgcgaggtcgacctggccgggttctac
gacagccgggccgccgagggctacgactacgggcccgcgctgcgcgggctgcgacgggcc
tggacccgcgacggcgaggtgttcgccgaggtggagctgcccgcaccgctgagcccggac
ggctggggcctgcacccggccctgttcgacgccgcgctgcacgccaccggcctgctgccc
ccggcgcgggtcgccgccgacgaggtgctgctgccgttctcctggcgggggaccaggctg
cgcgccaccggggcgaccgcgctgcgcgtgcgcctgaccgggaccgccgacgaccacgtg
ctgcgcgcctacgaccccgagggcgcgccggtcgtggaggtcgacgccctgcggctgcgc
ccggccccggccaccgcgctcgtcggctcgggcgcgctgttccgcgtcgagtgggtcgac
ctggacttgccggtgtccacaccggactccacgccgggcgcccccgtgctcgaccggccc
gtgctcgacctgcccggcggcgacgcccgcaccctcgtcggcctgaccctggaggccctg
cgcgagcacgacgagctgaccgtcgtcacgcgcggcgcggccgaggacccggccgccgcg
gccgtgtgggggctgctgcgcaccgcccagaccgagcggccgggccgcttcgccgtggtc
gacctggacgacgaccccgcctcgcgcgccctgctgcccgccctgcccgccaccggcgaa
ccgcaggtccgggtgcgcgcgggcagggcgagcgcgccgcgcctggcgcgcacccgcgac
gacggcctgccgctgcccgccgccccgacctggcgcctgacctgcgacggcggcacgttc
accgacctggccgcgaccccgagcccggccgcgaaccgcccgctggaacccggcgaggtc
cgggtgggcgtgcgcgccgcgggcgtcaacttccgggacgccgccgtcgtgctgaacgcc
gtgcccggccagcgcgggctcggcggcgaggccgcgggcgtggtcctggagaccggcccc
ggcgtcaccggcctcgcggtcggcgaccgggtgctcggcacgttcgaccgcgacttcggc
gcgttcggcccggtcgcggtcaccgacgcccggctgctcgcgcccgtcccgcccggctgg
gggttcgcgcgcgccgcctcggtgccggtcgcgttcctcaccgccctctacggcctgcgc
gacctcgcccaggtcgggccgggcgaccgcgtcctggtgcacgcgggcgcgggcggcgtc
ggcggcgcggccgtcaggctggccgcgctgctgggcgcggaggtgttcgccaccgcgtcc
ccggcgaagtggccggtgctgcgcgcgctcggcctggacgacgcgcacctggcctcctcc
cgcgacaccgggttcgccgagcgcttcccgaacgtcgacgtcgtgctgaactcgctcacc
ggcgagctggtggacgcctcgctgcggctgctcgcgccgggcgggcggttcctggagctg
ggcaaggtcgacgtgcgcgacctcgtgcgcgccgacgtgacctaccgggcctacgacctg
cgcgacgcgggcccggaccgcaccgccgaactgctcgccgaggtgctggggctgttcgcg
gcgggccgccttgagccgctgccgctgaccgtccgcgacgtccggcacgcccccgaggcg
ctgcggcacgtcgcgtccggcgggcacgtcggcaaggtcgtgctcaccgtcccccgcccg
ctcgaccccgagggcaccgtcctggtccacggcggcggcgcgctcggcgcgctcaccgcc
cgccacctggtgtccgcgcacggcgcccgccacctgctgatcacctcccggcgcggcccc
gacgcgcccggcgccgccgagctggccgccgacctcgccgaactcggcgccaccacgcgg
ttcgagcgctgcgacgccgccgaccgcgaccgggtcgccgccctgctggccgacctgggc
gggcgcccgctgaccgccgtcgtgcacacggcgggcgcgctcgacgacgccctgctcgcc
gaccaggacgcggcgcgcgtcgacgcggtcctgcgccccaagctcgacggggcgctgctg
ctggacgagctgacccgcgacgccgacctggccgcgttcgtgctgttctcctccgccgcc
gggacgctcggcaacgcgggccaggccaactacgccgccgcgaacgccgcgctcgacgcg
ctggccgcccgccgccgctccgccgggctgcccgccacctccatcgcctggggccactgg
gagcacaccagcgccctcaccgccgggctcaccgccgccgacctcgcgcgcggggccagg
cacggcgcgggctcgctcaccaccaccgaggcgctggccctgctcgacgccgcgctcgcc
tcgccggaacccgccgtcctcgccgccgcgctcgacccccgccgcgccgccgaggtcccg
ccgctgctgcgcgacctcgccggaccgcgccgggcggtcgcggcccaggccgtcgccggc
gcggaccggccgctgatcgacgtggtcagggcgcacaccgcgaccgtgctcgggcaccgc
gacgcctccgccgtggacgcgaaccgcgcgttcaaggagctgggcgtcgactcgctcacg
gccgtggagctgcgcaaccggctcgccgccgcgaccgggctcgcgctcgccgccacctcg
gtgttcgaccacccgaccccggcgctgctcaccgcgcacctgctcgccgagctcgggcac
gcccccgccgccgggaccaccgcgccccccgccaccgccgccgtcaccgccgacgcgggg
gagcccatcgcgatcgtgtcgatggcctgccgcttccccggcgacgtgtcctccccggag
gacctgtgggacctcgtcgcgggcggcggggacgcgctcaccccgttccccgccgaccgg
ggctgggacctggcggccctgttcgcccccgacccggaccgcgccgggcgcagccacgcc
cgcgagggcgggttcctcgccgacgtcgcgggcttcgacgccgacctgttcggcatcagc
ccccgcgaggccatcggcaccgacccgcagcagcggctgctgctggaggtggcgtgggag
ctgttcgagcgcgcgggcatcgcccccgactcgctgcgcggcaccgacaccggcgtgttc
gcgggcgtcatcgcgcacggctacccggtgctgcccgcccactccgaccaggggctggag
gggcaccgggtgaccggggtgtccgggagcgtggtgtccggccgggtcgcctacgccttc
gggctgcagggaccggcgatgaccgtggacaccgcctgctcgtcgtcgctggtgggcgtg
cacctggcggtgcgggccctgcgcggcggcgagtgctcgctggcgctggcgggcggcgtg
acggtgctgagcacgccggacctgttcgtggacttctcccggcagcgcgggctcgccgcc
gacgggcgctgcaaggcgttcggggcgggcgcggacggcaccgggttcggcgagggcgtc
gggctggtgctgctggagcggctgtgggacgcgcgccgcaacgggcgccgggtgctgggg
ctggtgcgcggcagcgcggtgaactccgacggggcctccaacgggctgaccgcgcccagc
ggccccgcgcaggagcgcgtcatcgggcgggcgctcgcggacgccgggctgtcggcggcc
gacgtggacctcgtggaggcgcacgggaccgggacccggttgggcgacccgatcgaggcg
cgggcgctggtggcgacctacgggcgggaccggggcggggagccggtgtggctcgggtcg
gtcaagtccaacatcgggcacacccaggccgccgccggggtcgccgggctgatcaaggcg
gtgcaggcgctgcggcacggggtgctgcccgcgaccctgcacgcggccgagcccaccccc
gaggtcgagtgggacggggtcgcggtgctggccgagcagcgggactggcccgaggtgggc
aggccgcgccgggcggcggtgtcctcgttcggggtcagcggcaccaacgcgcacgtggtg
ctggagcaggcgcccgaggagttgagccccgaggggcggatccccgaggtgcggatcccc
gacaggcggacttcagaggggcgggtgcctgaggggcgggcgcccgagggacggacgtcc
ggaggccgggcacccgagggccagacatccgagggccgggcgttcggcggccgggtgccc
gaagaccagacatccgaagaccggacatccgagggccaggcgtccatggggcgggcgcct
gagggccaggcgcccctgggccaggtgtccgagagccgggcgcccgaccaccgggtgccc
gccgggcccgaccgggacgtccccggtcacctgccgctcgtgctgtccgcgcacgacccg
gccgcgctgcgcgccaccgcggcccgcctgctgccggtcgccgagcgcgtcccgctgccc
gatctggcgctgtccctggtcaccggccgcgccgccctgccctgccgggcggtgatcccc
gcccgcgaccggggtcaggcgctggcggcgctgcgcgacctcgcgtccggcgccaccgcg
cccgccgagcgggacggcgggggcgtggcgttcctgctgtccggccagggcagtcagcgg
gccgggaccgggcggctgctggagcggcggttcccggtgttccgggacgcgctgcgcgag
gtgtgcgccctgctggaccggcgcgtcgtcggcggtcccggcgtgcgcgccgcgctggac
gaccccgggctgctcgccgacacccgctacgcgcaggccggcctgttcgccgtgcaggtc
gcgctggtgcgcctgctcgacgcgctcggcgtccgccccgacctgctcgccgggcactcg
gtcggcgagatcgccgtcgcgcacgccgccggggtgctgtccctggaggacgcctccacc
ctcgtggccgcgcgcggcgccctcatgcgcgagctgccccccggcgtgatggtcgcggtc
cgcgcgggcgaggacgaggcgcgcgccgcgctggtcgacggggtggagctggccgccgtc
aacggcccccgcgccaccgtgctcaccggcgacgaggccgccgtcaccgaggtcgccgcc
cgcctcgggcgcgccacgcgcctgcgggtcgcccacgccttccactcggccgccgtcgac
gcggtgctgcccgcgttcgccgacgtgctggcgcgcctggacttccgcccgccgcgcgtc
ccggtggccaccaccgcgcccggcgcgctcgacgcgcccgagtactggctgggccaggcc
cgcgagccggtgcgcttcgccgacgccgtcaccgacctgcaccggcggggcgcgaccgcg
ttcgtcgaggtcggccccggtggtgggctggccgccgccgcgcaggagtgcctggacggg
cacgacgtgctctgcgcccccctgctgcaccgcgaccgggacgaggaccactccctgatc
accgcgctcggcgcgctgcacgcgaggggcgcgcgcgtcgacttcgccccgctgctggcc
gacgcgggcggccggaccaccgacctgcccacctacccgttccagcgccgccgcttctgg
ctcgaccccgccccgcccaccaccgacgccgccccgctggagcacccgctgctcaccggg
gagctggagatccccggctcggacaccgccgcgttcaccggccgcgccgccaccggcgcc
cacccgtggctggccgaccaccggctgctcgacgcggtcgtcgtgcccggcacggccctg
ctggacctggtgcgggcggccggtcgccagctcgggctgcccgaggtcgccgagctggtc
aacgaggtcccgctggtgctcggcgacggggcggcgctgctgcgcgtcaccgccgccgcg
ccgggaccggacgggcggcgggaggtggccgtgcactcccggccggagtcggcagggccg
cgctcaccgtggacccggcacgtcaccggccagctcgcccccgagtcggggccgctcgcg
ttcgacctggcgcagtggccgccgccgggcgcgctgccgctgccggtggccgaccaccgg
gccgcgatggccgccaccggccacgggtacgggcccgcgttcctggggctgcgcgccgcc
tggaagctcgacgacgaggtgctggtggaggcggtcctgccggacgaggtcgccgacgac
gggcacgccgtgcaccccgcgctgctcgacgcggtgctccaggccatcgcgctcaccggc
gtcgaggacggctcgcaggtgcgggtgccgttcagctggcgctccgcgcgcggcgcgggc
cgggcgggccgcgcggtgcgcgcctccctgcggcccgacggcgacggcggcgtccgggtg
cgcgtggcctgcccgcggggccgcccgctgctggagatcgcctcgctggtgtcccggccg
gtcacccccgaccggctgcggccgggggtgctgctgcgccaggcgtggacggaggtcggc
ccgccgcccggcgccgccgagcccgtgccgctgcgcgaggtcggcgagcgggtgccgccg
gtggtgcgggtcgacgccgggcacgtccgcgacctgctgccgctgctccaggaggtggtg
accgagccccgctgggagtcgacgcggctgctcgtgacgacctcgggcgcggtggggccg
cgcgccggacgcgccgagggcgccgcggtgtggggcctggtgcggtcggccgccgccgag
cacccaggccggttcgtcctggccgacctggacgaccggcccgagtccgccgcgctgctg
cccgccctcgccaccggcgcgctgccggaggcggtgctgcgcgcgggacgcgtgctcgtg
ccggggctgcaccgggtctccgcgcccggcgcaggcggggccgtgctcgaccccggcggc
gccgcgctgatcaccggcggttccggcgcgctggccgcgctgctggccgagcacctggtg
cgcgcgcacggcgtgcgctgcctggtgctgctcagccgcagcgggcgcggaccggacgtg
ccgggcgccgacgtgcggcacgtgcgcggcgacgtcgcgaaccgggccgacgtggtcgcg
gcgctggccgccgtgccgccggaccggccgctgacgctggtggcgcacctggccggggtg
ctcgacgacggcgccctgaccgcgctgacccccgagcggctggacgcggtgctgcgcccc
aaggccgagggcgcccggcacctggacgagctgaccagggaccgggacctggcggcgttc
gtgctgttctcctcggtcgcgggcgcgctcggccacgccgggcaggccaactacgcggcg
gccaacgcccacctggacggcctcgcgcacgagcggcacgccctcggcctgcccgccacg
gcgctggcctgggggccgtggaccgagggcatggcgcgcggtcgcggaacgctctcgccg
caggtcgcgctcggcctgttcgacgcggccctgcgcaccggtctgcccgcgctcgtcccg
ctcgaccgcgaaccggagcgccgggtccccgccccgcgcgccgcgacccccgccccggcc
gggccgtcgctggccgaccggctgcgcccgatgccgcccgccgagcggcgcgcccacctg
ctggagctggtcaccgccgaggcgctgggcgtgctgggccacgacgacggggccgcgctg
cccgccgggcaggcgttccgcgacgccgggttcgactcgatcaccgcgatggcgctgcgc
aaccggctcgtccggctggccggggtgcggctgcccgcgagcgtggtgttcgaccacccc
accccggccgccaccgccgagcgcctggaggccgagctgttcccggccgaccggctgccg
gggccccggcacggcgacgacttcgacgacatggccgccgacgagctggtccgccgcgca
ctcggcggcgagtag
DBGET
integrated database retrieval system