| Entry |
|
|---|
| Symbol |
HERC2
|
|---|
| Name |
(RefSeq) E3 ubiquitin-protein ligase HERC2 isoform X1
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|---|
| KO |
|
|---|
| Organism |
apri Ahaetulla prasina (Asian vine snake)
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|---|
| Pathway |
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|---|
| Brite |
KEGG Orthology (KO) [BR:apri00001]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
131199296 (HERC2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:apri04121]
131199296 (HERC2)
03036 Chromosome and associated proteins [BR:apri03036]
131199296 (HERC2)
03400 DNA repair and recombination proteins [BR:apri03400]
131199296 (HERC2)
Enzymes [BR:apri01000]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
131199296 (HERC2)
Ubiquitin system [BR:apri04121]
Ubiquitin ligases (E3)
HECT type E3
131199296 (HERC2)
Chromosome and associated proteins [BR:apri03036]
Eukaryotic type
Centrosome formation proteins
Other centrosome associated proteins
131199296 (HERC2)
DNA repair and recombination proteins [BR:apri03400]
Eukaryotic type
DSBR (double strand breaks repair)
Other DSBR factors
Ubiquitin ligases
131199296 (HERC2)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
5:93320457..93435753
|
|---|
| AA seq |
4837 aa
MSSESFCLAAQIRFDSKWLKTDLQLAFTRDGLCGLWNEMVKDGEIVYTGIEVTQSGETSP
RKDESTEGQTGSKKEDQNDKERKDEDDTPPPTYRAKSIVESWIWGKQPDVNELKDCLYIL
VKEQQVLAKKTATTTLSALRLKQRLAILERYFIALNRSILLENVKVKRKSSTIPLPMVDK
KSPRSVSKGVEGLARVGSRAALSFAFAFLRRAWRSGEDADLCSELLQESLDALRALSEAS
LFDEGTVSSVWLEVVERATKFLRSVVTGDIHGAPGLKGSGSIPLQDQHLALAILLELAVQ
RGTLSQMLSAVILLLQLWDSGTRETDNERSAQGTSAPLLPLLQRFQNIICNKEMNNTEEE
IQMLAYPLSPNENFLRYLILPQDNELAIDLRQTAVVVMAHLDRLATPCMPPQCSSPTSHK
ASLQEFIAWGLIGWKYYSNVSCPIQCEGLASLGVTQIACAEKRFLILSKNGRVYIQAYSN
DTLAPQLVQSLASRNIVKIAAHSDGHHYLALAATGEVFSWGCGDGGRLGHGDTVPLEEPK
MISALSGKQAGKHVVHIACGGTYSAAITADGELYTWGRGNYGRLGHGSSEDQTIPVLVTG
LKGLKVIDVACGSSDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDV
VKVRCGSQFSLALTKDGQVYSWGKGDNQRLGHGTEEHVRFPKLLEGLQGKKVIDIVAGST
HCLALTEDSEVYSWGSNDQCQHFDTLRITKPEPTALPGLDSKHIVGIACGPAQSFAWSSC
SEWSIGLRVPFVVDVCSMTFEQLDLLLRQVTEGMDGSSDWPPPQEKECMAVATLNLLRLQ
LHAAISHQVDPECLGLGLGSVLLNSLKQTVVTLASNAGVLNTVQSAAQAVLQSGWSVLLP
TAEERARALSALLPSAVSGNETNVSPGRRFMIDLLVGSLMADGGLESALNAAITAEIQDI
EAKKEAQKEKEIDEQEANASTLHRNKTPLDKDLINTGIYESAGKQSLPLVQLIQQLLRNI
ASQTIAKLKDVARPISSSLDHEHYNKERSASLDLLLRFQRLLVSKLYPGDHFGQVSNTYS
PELLGVGSLLKKYTALLCTHIGDILPVATSIASISHRHFAEVSRVVDGDLTGVLLPELVV
SVVLLLSKNPGLIQEAGAIPLLAGLLEHLDRFSHLAPGKERDDNEDLAWPGIMGTFFTGQ
NCRNNEEVTLIRKADLENHNKDGGFWTVIDGKVYDIKDFQTQSLTGSGILAQFAGEDPIV
ALEAALQFEDTKESMHAFCVGQYMEPDQEVITTPDTGSLSSPLIDTERNLGLLLGLHASY
LAMSTPLSPVEIECAKWLKSSIFSGGLQTSQIHYSYNEEKDEDHCSSPGNTTPNKSKMYS
HRLTLTDHSQPFLQAIADNNIQDHTVKDFLCQVERYCKQCHLTTPITFPPEHPVEEVGRL
LLCCLLKHEDLGHVALSLVHPVMLGIDQVKHRILPKSVADVCRVVYQAKCSLIKTHQEQG
RSYKEVCAPVIERLRFLFNELRPAVCNDLSIMSKLKSLSSLPQWRRVVQKIIRDKRKKKA
PKKSETSDVEESKIGNEESDLGESCMIPHSPVTTDKRPLSVKSPKDKWQPLINTVTGVHK
YKWLKQNVQGLYPQSALLNTIVEFALKEEPVDVEKMRKCLLKQLERAEVRLEGIDTILKL
AAKSFLLPSVQYAMFCGWQRLIPEGINIGEPLTDCLRDVDLIPPFNRTLLEVTFGKLYSW
AVQNVRNILLDANSRFKELGIQPVPLQTITNENPAGPSLGTVPQARFLLVMLNMLTLQHG
ANTLNLLLNSGMLALMQTTLRLIGPSSDNVEEDMIAASRGVSATVLEESRKESTPVQLPV
SGPELAAMMKIGTRVMRGVDWKWGDQDGPPPGLGRVIGELGEDGWIRVQWDTGSTNSYRM
GKEGKYDLKLAEPPPASQPATEDSDTEDDSEGEHTEKNLHPTSMMLTSTVNLLQTLCLSA
GLHAEVMQNEATRTLCGLLRMLVESGTTEKSSSLPNTLVNKEQHRSWCTLGFIRSIALMP
QMCSTLSTSQWITLLMKIVEGHDSFTAASLQRQILAVHLLQAVLPSWDKTERSRDMKFLV
EKLFGFLGSLLTTCSSDIPLLRESTLRRRKARPQASLTATHSSTLAEEIVALLRTLHSLS
QWNALINKYINSQLTSITHIFAGKESEGAALEDCFPDSGTPEVGGLMAVLAVIGGIDSRL
RLGGQVVHEEFGEGTVTRITPKGKITVQFYDMRTCRVCPFSQLKPVPVVPFNVNNLPFTE
PMLSVWAQLVNLAGSKVEKQRMKTPNQGLSGQIDLDLLRCQQLKLYILKAGRALLSYQDK
LRQILSQPAVQDSSSVPTDDGAVASPEVGDMSPEGPQPPLILLQQLLTAATQPSPVKAIF
DKQELEAAALAVCQYLAVESGHPSTPVFEECSSSEATTPVTVQHIRPAKVKKCKASPIPP
LPIVVQLMEMGFPRKNIEFALKSLSGTSGSASGLPGVEALVGWLLDHPDVQITDFSDGDT
ISDEYSDDEVSEEVEEAEAAYPVSAVVTESQTYKKRADFLSNDDYAVYVRENIQVGMMVR
CCRTYEEVCEGDVGKVIKLDRDGLHDLNVQCDWQQKGGTYWVRYIHVELIGFPPQSSPSH
IKIGDKVRVKTSVMTPKYKWGSVTHRSVGVVKAFSANGKDVIVDFPQQSHWTGLLSEMEL
VPSIHPGVTCDGCQMFPINGPRFKCRNCDDFDFCETCFKSRKHNTRHTFGRINEPGQSPV
FCGRSGKQLKRHHSSQRGMLLDDWSRIVKNLNVSSSVNQASRLIDGSEQCWQSSGSQGKH
WIRLEIFPDVLVHRLKMIVDPADSSYMPSLVVVSGGSSLNNLIELKTININPTDTTVPLL
GDCTEYHRYIEVAIKQCRSSGIDCKIHGLSILGRIRAEDEDLAAVPFLASDNEEDDDDKA
NTGSLVRKKTTGLESAASIRTKVFVWGLNDKDQLGGLKGSKIKVPSFSETLSALNVVQVA
GGSKSLFAVTVEGKVYACGEATNGRLGLGLSSGTVPIPRQITALSNYVVKKVAVHSGGRH
AMALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKRIRDIACGSSHSAAITSSG
ELYTWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVVQVACGSRDAQTLALTDEGLVFSWG
DGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLG
HGTDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDTGQVYAWGDNDHGQQGNGTTTVNR
KPTLVQGLEGQKITRVACGSSHSVAWTTMDVATPSVHEPVLFQTARDPLGASYLGVPSDA
DSSASSNKINGINSSKSNRPSLAKILLSLDGNLTKQQSLSHILTALQIMYARDAVVGALM
PASMIAPVECLSSSPAPPPDLACIGSAPSLDESMLAIDTEDRQSPTPWQDRRVEVASAED
ALTPSAVTPSASAASSRPFIPVTDDPGAASIIAETMTKTKEDVESQSKVSGPEPQYLDEF
TSLLVPDDTRVMVDLLKLAVSGRAGEKGKDVLSAVLSGMGTAYPQVADMLLELCVTELED
VATDSQSGRLSSQPVVVESSHPYTDDTSTSGTVKIPGAEGLRVEFDRQCSTERRHDPLTV
MDGVNRIVSVRSGREWSDWSSELRIPGDELKWKFISDGSVNGWGWRFTVYPIMPAAGPKD
LLSDRCILSCPSMDLVTCLLDFRLNFASNRSIVPRLAASLAACAQLSALAAGHRMWALQR
LRKLLTTEFGQSININRILGDNDGEARTMSFTGSALAALVKGLPEALQRQFDYEDPIVRG
GKQLLHSPFFKVLVALACDLELDTLPCCAETHKWAWYRRYCMASRVAVALDKRTPLPRLF
LDEVAKKIQELMADHENIDILHESHEVFKREQDEQLVQWMNRRPDDWTLSAGGSGTIYGW
GHNHRGQLGGIEGAKVKVPTPCEALATLRPVQLIGGEQTLFAVTADGKLYATGYGAGGRL
GIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRS
PCDRPRVIESLRGIEVVDIAAGGAHSACITAAGDLYTWGKGRYGRLGHGDSEDQLKPKLV
EALQGYRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGV
GVIKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATG
SLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKINRVACGSAHTLAWS
TSKPANAGKLPSQVPMEYNHLQEIPIIALRNRLLLLHHISELFCPCIPMFDLEGRLDETG
QGPSVGFDALRGILISQGKEAAFRKVVQATMVRDRQHGPVVELNRIQVKRSRSKGGLAGP
DGTKSVFGQMCAKMSSFSPDSLLLPHRVWKVKFVGESVDDCGGGYSESIAEMCEELQNGL
TPLLIVTPNGRDESGANRDCFLLNPAAKTSLHMNMFRFLGVMLGIAIRTGSPLSLNLAEP
VWKQLAGMNLTIADLSEVDKDFIPGLMYIRDNEATSEEFEAMSLPFTVPNASGQDIQLSS
KYTHITLDNRTEYVRLAINYRLHEFDEQVAAVREGMARVVPVPLLSLFTGYELETMVCGS
PDIPLHLLKSVATYKGIEPSASLIQWFWEVMESFSNTERSLFLRFVWGRTRLPRTIADFR
GRDFVIQVLDKYNPPDHFLPESYTCFFLLKLPRYSCKQVLEEKLKYAIHFCKSIDTDDYA
RIALTGEPTADDSSDDSDNEDADSFASDSTQDYLTGH |
|---|
| NT seq |
14514 nt +upstreamnt +downstreamnt
atgtcttctgaatccttttgtttggctgctcagattagatttgattccaaatggctgaag
acagacttacagcttgcatttaccagagatggactctgtggtctttggaatgaaatggtc
aaagatggagaaattgtatatactggaatagaagttacccaaagtggtgaaacatctcca
cgaaaagatgaaagcactgaaggccaaactggatcaaagaaagaagatcagaatgacaaa
gagaggaaagatgaggatgatacaccaccacctacctacagagctaaatcaatcgttgaa
agttggatttggggaaaacaaccagatgtcaacgaactgaaagactgcctttatatatta
gtaaaagagcaacaggttctagctaagaagactgctaccacaactctctctgctctcagg
ctgaaacagaggcttgctatattagaacgctactttatcgcattaaataggagcattctt
cttgagaatgtcaaggtgaagcggaaaagcagcactatcccattgcccatggtggataag
aaaagccctagatctgtaagcaaaggtgttgaaggtcttgcccgagtaggatccagagcg
gctctttcgtttgcctttgcattcctacggcgagcttggagatcaggtgaggatgcagat
ctttgcagtgaattattacaagaatctctagatgcgctgcgagccctatcagaagcatcc
ttgtttgacgaaggaacagtatcctctgtatggttggaagttgtggaaagagcaactaaa
tttctaaggtctgttgtaactggagacattcatggagctccaggtttaaaaggctcagga
agcattccactgcaagaccagcacttagcacttgctatattactggaattagctgttcag
agaggcacgctgagccaaatgttgtctgctgtgatactattgcttcaactctgggatagt
ggaacaagagaaacagataatgaacgctcagcacagggaaccagtgccccactccttcct
ttgttacagagatttcagaatataatttgtaacaaagagatgaataatacagaagaagaa
attcagatgttggcttatccactaagtccaaatgaaaacttcctaagatacctaatactg
ccacaggacaatgagctagcaattgatttaagacaaacagcggttgtggttatggctcac
ctggatcgcctagccactccctgcatgcccccacagtgcagctctccaacatctcataag
gcttctttgcaggagtttatagcatggggattaataggatggaaatactactctaatgtc
agttgtccaattcaatgtgaaggacttgccagtcttggagttacacagattgcttgtgca
gagaagcggtttctgatcttgtccaaaaatggacgtgtttatatacaagcctacagtaat
gacacattggcaccacaacttgtacagagtcttgcttctagaaatattgttaaaattgca
gcacactcagatggacatcactatctggctttggctgcaactggagaagttttttcttgg
ggttgtggagatggtggacgactgggccatggagatactgtgcctttagaagaaccaaaa
atgatttctgctctctctgggaagcaggctggaaaacatgttgtacatattgcatgtgga
ggtacctacagtgctgcaataacagctgatggagaattgtacacgtggggccgaggaaac
tatggcagactaggtcatggctccagtgaagaccagacaatcccagttttggttactggc
ctgaaaggattgaaagtgattgatgtagcctgtgggagtagtgatgctcagactcttgct
gtaacagaaaatggtcaagtatggtcttggggagatggagattatgggaaattgggaaga
ggtggcagtgatggctgcaaaactcccaaactgattgaaaaacttcaagacttggatgtt
gtcaaagtacgctgtgggagtcagttctcacttgcgctaacaaaagatggacaggtgtac
tcatggggaaagggagacaatcagagacttgggcatggaacggaagaacacgttcgtttt
cccaaattgctggaaggcttgcaagggaaaaaagttatagatatagtagctggctctact
cactgtttagcgctcacggaagatagtgaagtctatagctggggaagcaacgatcagtgc
cagcattttgacactttgaggattactaaaccagagccaactgctcttccaggactggac
tcaaaacacattgttggtattgcctgtggaccagcccagagctttgcctggtcgtcttgt
tcagaatggtcaattggtttacgtgtcccctttgtggtagatgtttgctcaatgacattt
gaacagctggatctcctattgagacaagttacagaaggaatggatggcagttctgactgg
ccacctccacaggagaaagaatgtatggctgtggctactttgaatcttctaaggctacag
cttcatgctgcaattagtcaccaagttgatcccgaatgccttggcttggggttaggcagt
gtcttgctcaacagtctgaagcagacagtagtgactttagcaagtaatgctggtgtgctt
aatactgtgcagtcagctgcccaagcagtgttgcaaagtggatggtctgtgttgctacca
actgcagaggaacgagcaagagctctttcggcacttttacccagtgcagtttcagggaat
gaaacaaatgtaagtccaggtcgtagatttatgattgatctactggttggaagtttgatg
gctgatggcggtctagaatctgcactgaatgctgctattactgcagaaattcaggatatt
gaggcaaaaaaagaagctcagaaagaaaaagaaattgatgagcaggaagcaaatgcatcc
acacttcacaggaacaagacaccattagataaagacctcattaatactgggatctatgaa
tctgcaggaaaacaaagcttgccgttggttcaattaatccagcaactattgaggaacatt
gcttcacaaactattgctaaattgaaagatgtggctcgtcccatttcttcttctttagac
catgaacattataataaagaaaggtctgcttctttggacttactgctgcgttttcagcgc
ttgcttgttagtaagttatatccaggagatcattttggacaggtctctaatacatacagt
cctgagcttctaggagttggttctctgctaaagaaatacacagcccttttatgtacacac
attggagatattttgcctgtagcaactagcattgcttctattagccataggcattttgca
gaagtatctcgtgttgtagatggggatttaacaggtgtactccttccagaattagtggta
tctgtagtactccttctcagtaaaaatcctggacttattcaggaagctggagcgattcct
ttattagctggcttattagaacatctggacagatttagccacttagctcctggtaaagag
agagatgacaatgaagacttagcttggcctggaataatgggtacattctttacagggcag
aattgcagaaataatgaggaagtgacacttatacgaaaagctgacttggaaaaccacaat
aaagatggtggcttttggacagtgattgatggcaaagtgtatgatataaaagatttccaa
acccaatcattaacagggagtggtatacttgcccagtttgcaggagaagatccaattgtt
gctttggaggcagctttgcagtttgaggatacaaaagaatcaatgcatgctttctgtgtt
ggccaatatatggagcctgatcaggaagtgatcacaacaccagatactggcagtctctca
tctcctctcatagacactgaaagaaatttaggcctcctgcttggtctacatgcttcctat
ctagcaatgagtacaccactttctccagtggagattgaatgtgccaagtggctgaagtcc
tctattttttctggaggcctgcaaactagtcagatacattatagttacaatgaagaaaag
gatgaagaccactgtagctctcctggcaacaccacaccaaacaagtcaaagatgtattcc
catcgactaactttgactgaccactcacagccttttctacaagctattgcagacaacaat
attcaggatcacactgtgaaggacttcttatgtcaagttgagaggtactgcaagcagtgt
catttgacaacaccaattacattccctcctgagcacccagtagaagaagtaggacgtttg
ttgttatgttgccttctcaagcatgaggatttaggtcatgtagcactttctcttgttcat
cctgttatgcttggaattgaccaagtgaaacaccgaatactcccaaaatctgtagcagat
gtttgtcgtgttgtctatcaagcaaaatgttcactgatcaaaacccatcaagagcaagga
agatcttacaaagaagtctgtgctcctgttattgaacgcttgagatttctcttcaatgaa
ctgcgcccagcagtgtgcaatgatctctccatcatgtccaaacttaaaagtcttagttct
ttgccccaatggagaagggtagtccagaagataattagagataagagaaaaaagaaagct
cctaaaaaatccgaaacttctgatgtggaagaatccaaaattggaaatgaggaaagtgat
ttgggcgagtcatgtatgatacctcatagtccagtgacaactgataaaaggcctttgtct
gtcaaatcacctaaggataaatggcagccgctgataaatacagtcacaggtgttcacaaa
tacaagtggctgaagcaaaacgtccaagggttatatccccagtctgctttactcaacacc
atagttgaatttgctctgaaagaggaacctgttgatgtagaaaaaatgaggaagtgttta
ctaaagcagctagagcgagcggaagttcgattagaggggattgatacaattctaaaattg
gccgccaaaagcttcttgctgccttctgtgcaatatgctatgttctgtggatggcaaagg
cttattccagaagggattaatataggagagcctttaacagattgcttaagagatgttgat
ctgattccaccctttaaccgtacacttctggaagttacctttggaaagttgtattcatgg
gctgttcaaaatgttagaaacattttgcttgatgctaacagcagatttaaggaattagga
atccagcctgttcctctgcagactataaccaatgagaatcctgcaggaccaagtcttgga
accgtcccacaagcacgttttttattggtcatgcttaacatgttaactttgcaacatggt
gcaaataccttgaatcttcttctcaattctggcatgttggcattaatgcaaaccacactg
aggctaataggaccgagctccgataatgtggaagaagatatgattgctgcatcccggggt
gtttctgctacagtcctagaagagtccaggaaggaaagcactccagttcagcttcctgtt
tcaggaccagaattggcagccatgatgaagattggtactagagtgatgagaggagtagat
tggaagtggggtgaccaggatgggcctcctccaggtttgggacgggtaattggagaactg
ggtgaagacggttggattcgagtacagtgggacaccggcagtaccaattcttatcggatg
ggaaaagaggggaagtatgatctgaagctagccgaacctcctcctgcttcacaacctgca
actgaagactctgacactgaggatgattctgaaggagaacacactgaaaaaaatctccat
cctacttccatgatgctgaccagcacagtgaatcttttgcaaacactctgcctttctgct
ggtcttcacgctgaagtaatgcagaatgaagcaacgagaactctgtgtggattgctccgc
atgctggtagaaagtggcacaacagaaaaatcatcttccttgccaaatacattagttaac
aaagagcaacaccggagctggtgtaccctgggattcatccgaagtatagcactgatgcct
caaatgtgcagcactcttagtacatcacaatggataacactgctaatgaaaattgtagaa
ggacatgattcattcactgctgcatctctccaacgacagatccttgctgtgcacttacta
caagcagtgcttccttcctgggataaaacagaaaggtcacgggatatgaaattccttgtg
gaaaaattatttgggtttttgggtagcttgctgactacatgttcttcagatatcccactg
ctcagagaatctactctgaggaggaggaaagctaggcctcaggcctccctgacagcaact
cacagcagtactttagctgaagagattgttgctctattgaggactttgcattcattgagc
cagtggaatgcactcataaacaagtatatcaactctcagctaacctccatcacccacatc
tttgcaggaaaagagtcagaaggggctgctttggaagactgttttcctgattctgggact
ccagaagtgggaggcctgatggctgttttggcagttattggtggaatagacagtcggttg
cggttaggtggtcaagtagttcatgaggaatttggagaaggcacggtgacaaggattact
ccaaaaggaaaaatcacagtgcaattttatgatatgagaacctgcagagtttgtcctttc
agtcaactaaaaccagttcctgtggttccatttaatgtgaataacttacccttcactgaa
cccatgctttctgtctgggctcagttggtaaatctggctggcagtaaagtagaaaaacaa
agaatgaagactcccaaccagggcctttctggacaaatagatttggatctcttgagatgt
cagcaattaaagctatacatattaaaagcaggccgagctctgctttcttaccaggataaa
ttaaggcagatcttatctcaaccagcagtacaagattctagttcagttcccacagacgat
ggtgcagtggcatcacctgaggtgggagacatgtctccagaagggccccagcctcccttg
atcctcttgcagcaactgttgacagcagcaacacaaccatctccagtaaaagcaatattt
gataaacaagagcttgaggctgctgcacttgctgtatgtcaatatctggctgtagaatct
gggcatccttcaactccggtctttgaagaatgtagctccagtgaagctacaacacctgtt
acagtccaacatatccgacctgcaaaagtaaaaaaatgcaaggcatctcccattccacca
ctcccaattgttgtgcaacttatggaaatgggattccctagaaagaatattgagtttgca
ttgaaatcactatcaggaacttctggaagtgcttctggattaccaggggtagaagccttg
gtgggctggcttttggatcatcccgatgttcaaattaccgatttctcagatggtgacact
atatctgatgaatattcagatgatgaagtgtcagaagaagtagaggaagcagaagccgcg
tatccagtgtctgctgttgtaacagaaagccaaacatataagaaaagagctgatttctta
agtaatgatgattatgccgtatatgtccgggagaatattcaggtggggatgatggtccga
tgttgcagaacttatgaggaggtttgtgagggagatgtgggtaaagttataaagttggat
cgtgatggtttgcatgatctcaatgtgcagtgtgactggcaacaaaaaggtggcacttac
tgggtcagatatatccacgtggaactgataggattcccaccacagagttctccatcacac
ataaagattggtgacaaagttcgtgtaaagacttctgtaatgacacccaaatacaaatgg
ggatctgttacccacagaagtgtgggtgtagtaaaagcttttagtgccaatggtaaagat
gttattgttgacttccctcaacaatctcattggactggattattgtcagaaatggagctg
gttcccagtattcacccaggagttacgtgtgatggctgtcagatgttccctattaatgga
cctagatttaaatgcagaaactgcgatgattttgatttctgtgaaacctgcttcaaaagt
aggaaacataatacaagacacacttttggcagaataaatgaaccaggccagtctccagta
ttttgtggtcgctctggaaagcagctaaaaagacatcatagtagccagcgaggcatgcta
cttgatgattggtccagaattgttaaaaatttgaatgtgtcatcttctgtgaatcaagct
tctcgtttgattgatggaagtgaacagtgttggcagtcctctggctcacaaggaaagcac
tggatacggttggaaatttttcctgatgtcctggtacacagattgaagatgatagtggac
cctgcagacagcagttacatgccttctttagttgtggtctcaggtggaagttctttgaat
aacctcatagagttgaagactatcaatattaatcctacagatacaacagttccactcctt
ggtgattgcacagagtatcacagatatattgaggtggctattaagcagtgcaggagttct
ggcattgactgtaagatacatggcctgagtatcctaggacgtatccgtgcagaggatgaa
gacttagctgcagttcccttccttgcttctgataacgaagaagatgatgatgataaagca
aacactgggagtcttgttagaaagaagactacaggcctcgaatctgcagcttcaattagg
acgaaagtctttgtctggggcttaaatgataaagatcaactgggaggattgaaaggttct
aagatcaaagtgccttccttttctgaaaccctgtctgctttgaatgtggtgcaagtagct
ggcggttctaaaagtctttttgcagtgactgtggagggtaaagtgtatgcctgtggagag
gctacaaatggaaggcttggattaggcctctcaagtggaacagttcctattcctcgacag
attactgcactcagtaactatgtagtcaagaaagttgctgttcactcaggtggtcgccat
gctatggctttaactgttgatggcaaggtattctcctggggagaaggagatgatggaaaa
cttggacatttcagtagaatgaactgtgataaaccaaggctgatagaagcactgaaaaca
aaacgtattcgagatattgcctgtggcagttcccatagtgctgctattacttcaagtgga
gaattatatacctgggggcttggtgaatatggccgactaggacatggggacaatactacg
cagcttaaaccaaagatggttaaagtacttcttggccatagggtcgttcaagttgcttgc
ggaagcagagatgctcagactctggctttgacagatgaaggtctagtattttcctgggga
gacggagattttggaaaactgggtcgaggaggaagcgaaggatgcaacattcctcagaac
attgaaagactgaacggacagggagtttgtcagattgaatgtggagctcagttctctttg
gctcttacgaaatctggagtagtgtggacgtggggcaaaggagactactttaggctagga
catggcactgatgttcatgtacgaaaaccccaagtagtagaaggtctgagaggaaagaag
atagtacatgtagctgtgggtgctctccactgcttagccgtcacagacactggtcaggta
tatgcttggggtgataatgatcatggacagcaaggcaatggaactaccacagtcaacaga
aagcccactctggtgcagggtttagaaggccagaaaataacccgtgttgcatgtggatct
tcccatagtgtggcttggacaacaatggatgttgctacaccatctgttcatgaaccagtt
ctctttcaaactgcaagggaccctttaggcgcatcttatttgggtgttccatcagatgcc
gattcttctgcttcaagtaacaaaatcaatggtataaacagctctaaatctaaccgacct
tcacttgctaagatccttttgtcattagatggaaaccttaccaagcagcagtcattatct
catatactgacagcactacagatcatgtatgctagggatgctgtggttggagcactgatg
cctgcaagtatgattgcaccagtagagtgtttgtcctcatctcctgcgccacctccagac
cttgcttgcataggcagtgctcctagcctggatgaaagcatgctagcaattgatacagag
gacaggcagagcccaacaccttggcaagacaggagggtggaggtggcttctgcagaagat
gccttgactccctctgctgtgaccccctctgcttcagcagcttcatctcgcccttttatt
cctgtcacagatgatcctggagcagccagtataatagcagagacaatgaccaaaaccaaa
gaagatgtagaaagccaaagcaaagtctctgggccagaacctcagtacttggatgaattc
accagtctcttggtaccggatgatacccgagtcatggttgacttactgaagttggctgta
tcaggacgtgctggagagaaggggaaagacgtcctttctgctgtgctgtctggcatgggt
acagcttatcctcaggtggctgatatgttgctggaactgtgtgttactgagttggaagat
gtggcaactgattcacaaagtgggcgtctctcttctcagccagtggtggtagaaagtagt
catccatatactgatgatacttctaccagtggcactgttaaaataccaggtgctgaaggt
cttagagtagaatttgaccgccagtgctccacagaacgacgccacgatcctctcactgtc
atggatggagtcaaccggatagtttctgtgagatcaggtcgtgaatggtctgactggtct
agtgaactgcgcattccaggtgatgaattaaaatggaaatttatcagtgatggctctgtg
aatggatggggttggcgcttcacagtttatcccatcatgccagctgcaggtcccaaagat
cttctttcagatcgctgtattctttcttgtccgtcaatggatttggtaacatgtttactg
gatttccgtttgaattttgcttctaacaggagcatagttcctcgcttagcagcttcatta
gctgcatgtgctcagctgagtgctctagctgctggccaccgaatgtgggctttacagaga
ttacgaaagttactgactactgagtttggccaatcaattaatatcaatcgaatcctagga
gataatgatggtgaagcacgaactatgagtttcactggcagtgccttagctgctctagtt
aaaggccttcctgaggcgttacagcggcagtttgattatgaagatcccattgtcagaggt
ggcaaacaactgcttcatagtcctttttttaaggtgcttgtagcccttgcttgtgatctg
gaattggatactcttccctgctgtgcagagacacacaaatgggcttggtatagaagatac
tgcatggcttccagagttgctgtagcccttgataaaagaacaccactgcctcgcctcttt
cttgatgaggttgccaagaaaattcaagaattaatggcagatcatgaaaatattgatatt
ctgcatgagagccacgaagtttttaaaagagaacaagatgaacaacttgtacagtggatg
aacaggagaccagatgactggacactttctgcaggaggcagtggaacaatatatggctgg
ggccataatcatagaggacaacttggaggtatagaaggagcaaaagttaaggttcctaca
ccgtgtgaagctcttgctacgcttagaccagtacagttaataggtggtgagcagacactt
tttgcagtgactgctgatgggaagctctatgccacaggatatggtgcaggtggaagactt
ggaattggggggacagaatctgtttctactcccacattgctagaatccattcagcatgta
tttatcaagaaagttgctgtgaattctggaggaaaacattgtctagcattgtcttcagag
ggagaagtttattcctggggtgaggcagaagatggcaaactgggccacggcaaccggagt
ccttgtgatcgtcctcgagtaattgaatctttgcggggcatagaagttgttgatattgct
gctggtggagcacacagtgcatgtattactgctgcaggagatctttatacatggggcaag
ggaagatatggacgtcttggccatggggacagtgaggatcagttgaaacctaaactggtt
gaagcactccagggttaccgtgtaattgacatagcctgtggcagtggggatgcacagacc
ctctgtttgacagatgatgatactgtctggtcctggggagatggagactatggaaagctt
gggagaggcggaagtgatggctgcaaagtgccaatgaagattgattctctcactggtgtt
ggagtaattaaagtagaatgtggctcacaattttctgtggcccttaccaaatcaggagcc
gtgtatacttggggcaaaggcgattaccatcgattaggtcatggatcagatgaccatgtt
cgaagacctcgacaagtccagggtttacaaggaaagaaagtaattgccatagcaacaggc
tctttacactgtgtgtgttgtactgaagatggtgaagtctatacctggggagataatgat
gaagggcagcttggagatgggacaactaatgccatccaaaggccacgtctggttgcagca
cttcagggtaaaaagatcaacagagtagcttgtggttcagcgcatactttagcttggtct
actagtaaacctgctaatgcaggcaagcttccttcccaggttcccatggaatacaatcat
ctacaggaaattcctatcattgccttaaggaacagattgctgttactacatcacatttcc
gagctcttttgtccttgtattcccatgtttgatcttgaaggacgccttgacgaaactggc
cagggtccctcagtggggtttgatgcattacgaggaattttgatatcacaaggaaaggag
gcagcttttagaaaagttgtacaagcaactatggtgagagatcgtcagcatgggccagtt
gtagaactcaacagaatacaagtaaagcgatctagaagcaaaggaggattggctggtcct
gatggcacaaaatctgtgtttggacagatgtgtgctaagatgagctcattcagtccagat
agtcttcttctacctcatcgtgtttggaaagtcaagtttgttggtgaatctgtggatgac
tgtggtgggggctacagcgaatcaatagcagaaatgtgtgaagaacttcagaatggactg
accccattattaattgtgactcctaatggaagggatgaatctggagcaaacagagattgc
tttctcctaaaccctgcggcaaaaacttcattgcacatgaacatgtttcgcttccttgga
gttatgctggggatagctattcggactggaagtcctctgagccttaatctggcagaacct
gtgtggaaacaattggcaggaatgaatttaacaattgctgatctcagtgaggttgataag
gattttattcctggacttatgtatatccgagacaatgaagctacctcagaagaatttgaa
gccatgagcctgccatttacagtgccaaatgccagcggccaagatattcaactcagttcc
aaatatactcatattacactggataatcgaacagaatatgtgaggcttgcaataaactac
agattacatgaatttgatgaacaagtggctgctgttcgagaagggatggcccgggttgtc
cctgttcctcttctttcactattcacaggatatgaactggaaactatggtgtgtgggagt
ccagatattcctctccatcttttgaaatctgtggctacatacaaagggattgaacccagc
gcttctctaattcagtggttttgggaggtgatggaatccttctccaacacagaacggtct
ctgtttttgcgctttgtatggggtaggacaagacttccaagaaccattgcagatttcaga
ggcagggactttgtcatccaggttctggataaatacaatcctccagaccattttcttcct
gagtcctacacatgcttttttctgctgaagcttcctaggtattcttgcaaacaggttcta
gaagagaaactaaaatatgccatccatttctgtaaatctatagacacggatgactatgct
cggatagcattgacaggggagccaactgctgatgacagcagtgatgattctgacaatgaa
gatgctgattcttttgcttctgactccacacaagactatttaactggccattga |
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