Amycolatopsis sp. FBCC-B4732: MUY14_04855
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Entry
MUY14_04855 CDS
T08335
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
aprt
Amycolatopsis sp. FBCC-B4732
Pathway
aprt00300
Lysine biosynthesis
aprt00550
Peptidoglycan biosynthesis
aprt01100
Metabolic pathways
aprt01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
aprt00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
MUY14_04855
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
MUY14_04855
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
MUY14_04855
Enzymes [BR:
aprt01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
MUY14_04855
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
wHTH-HSP90_Na-assoc
Motif
Other DBs
NCBI-ProteinID:
UOX89968
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Position
1216060..1217562
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AA seq
500 aa
AA seq
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MIVLSLAEIADVVGGRLHRAEPGVRVTGSVEFDTRQLTPGGLFVALPGEKVDGHDFAAQA
VEAGAVAVLAAREVDAPAIVVPPLGEGEAHERSVALTGDKDGSGAAVLGALAKLARYVVQ
RLAEGELTVVGVTGSSGKTSTKDVIAQLLEPLGPTVAPPGSFNNELGHPWTALRADASTR
HLVLELSARGPGHIAHLAEIAPPKIGVVLNVGTAHVGEFGSREGIAKTKGELVEALPADG
VAILNADDPLVSAMASRTKARVVFVGESPSAQVRAEGITLDDEARASFRLVTPAGEADVK
LPLHGEHHVGNALSAAAVALELGATPAEVATRLSGLERRSARRMEVVTREDGVTILNDSF
NANPESMRAGLKALAAMTRESGRRSWAVLGVMGELGADAITAHDEIGRLVVRLNIAKLVV
IGPEAAAMHQGAHQEGSWGEESTLVPDVRAAIALLHDQLRPGDVVLVKASKAAGLWRVAE
ALLEPRETDNSENRSNGGDA
NT seq
1503 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgtgctcagcctggccgagatcgccgacgtcgtcggcggccggctgcaccgcgcc
gaaccgggcgtgcgggtgaccggcagcgtggagttcgacacccggcagctcacccccggt
ggcctgttcgtcgccctgccgggcgagaaggtcgacggccacgacttcgccgcgcaggcc
gtcgaggccggcgccgtcgccgtgctggccgcccgcgaggtcgacgcgcccgcgatcgtc
gtgcccccattgggggagggggaggcccacgagcggtcggtcgcgctgaccggcgacaag
gacggctccggcgccgcggtgctgggcgcgctggccaagctcgcccggtacgtcgtgcag
cggctggccgagggcgagctgaccgtcgtcggcgtcaccggctcgtccggcaagacgtcg
acgaaggacgtcatcgcgcagctgctcgagccgctcggcccgacggtcgcgccgcccggg
tcgttcaacaacgagctcggtcacccctggacggccctgcgggccgacgcgagcacccgc
cacctcgtgctggagctgtccgcgcgcggccccgggcacatcgcccacctcgccgagatc
gcgccgccgaagatcggcgtcgtgctcaacgtcggcaccgcgcacgtcggcgagttcggc
tcgcgcgaaggcatcgcgaagaccaagggcgagctggtcgaggccctgcccgccgacggc
gtcgcgatcctcaacgccgacgacccgctggtcagcgccatggcgagccgcacgaaggcc
cgggtcgtgttcgtcggcgagagcccgtccgcgcaggtccgcgccgagggcatcaccctc
gacgacgaggcccgcgcgtccttccggctggtcaccccggccggcgaggccgacgtcaag
ctgccattgcacggcgagcaccacgtcggcaacgcgctttcggccgcggcggtcgccctg
gagctgggcgcgaccccggcggaggtcgccacgcggctctcgggcctcgaacggcggtcc
gcgcgccgcatggaggtcgtgacgcgcgaagacggcgtcacgatcctcaacgactccttc
aacgccaaccccgagtcgatgcgggccggcctcaaggcgctcgcggcgatgacgcgggag
agcggccgccggtcctgggccgtgctcggcgtgatgggcgagctcggcgcggacgcgatc
accgcgcacgatgagatcggccgcctggtcgtccggctcaacatcgccaagctcgtcgtg
atcggcccggaagcggccgccatgcaccagggggcgcaccaggagggttcctggggcgag
gaatcgaccctggtacccgacgtacgcgccgccatcgccctgctgcatgatcagctccgc
cccggggacgtggtgctggtgaaggcctccaaggccgccggcctctggcgggtcgccgaa
gcactgctcgaaccccgggaaaccgacaactccgagaatcgctcgaacggtggtgacgcg
tga
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