Lancefieldella parvula: Apar_0481
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Entry
Apar_0481 CDS
T00983
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate/D-alanyl-D-alanylligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
apv
Lancefieldella parvula
Pathway
apv00300
Lysine biosynthesis
apv00550
Peptidoglycan biosynthesis
apv01100
Metabolic pathways
apv01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
apv00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Apar_0481
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Apar_0481
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Apar_0481
Enzymes [BR:
apv01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Apar_0481
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ACV50912
UniProt:
C8W9X4
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Position
549380..550816
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AA seq
478 aa
AA seq
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MVKLSVEQIVAATHAQLLHRGTREVAGCAVIDSREVQQGSLFVAFAGEKVNGNSYLLSAA
QAGAAVVVASEPVTDNLLDSLAATGASVLEAADDDCEAFLLALAAAWREAHPNWLVVGVT
GSVGKTTTKEMLRRGIGATRRVHATAGNHNNLIGLPLTVLSTPEDTEVLVLELGMNHAGE
ITRLTSVARPTVAVITNVGTSHIGLLGSRKNIARAKAEIVSGMRAFGSIEPTLIQASAGD
YTKFIADKFARPARVVCKTVGATEDDVMSAQKVILDEKGLPTATISASSGWSRTVTLEVP
GRVVVDDLLLALEAVETLGLDLDAAAEAIEQMPATRMRLSVLDATCGAKIIDDSYNASPN
STAAALDVLMQMPAEGRRIALIGEIGELGPEEKRLHGYVGAYIAAKNPDFVAFVGTGAAR
EMVEAARVMGFSEDKIEQFNDVNEALAVLGPVLKQGDVLLAKASRSAQLDIFVKGVTE
NT seq
1437 nt
NT seq
+upstream
nt +downstream
nt
atggttaagctttcggttgaacaaatagtcgcagctactcatgctcagctgctccatcgc
ggaactcgcgaggttgcgggctgcgctgtgattgactctcgcgaggttcagcaaggctcg
ctcttcgtggccttcgctggcgagaaggtcaatggaaactcgtatcttttatctgctgct
caggcgggcgctgctgttgttgtggcatcagaacctgtaacagacaatctgcttgacagc
ctagccgccacaggagctagtgttcttgaagccgctgatgatgactgtgaggcgtttttg
cttgctcttgccgctgcttggcgagaagcacatccaaactggctggttgtgggtgtaact
ggatcagttggtaaaactaccaccaaagaaatgcttcgtcgcggcattggcgctactcgt
cgtgtgcatgctaccgccggcaaccataacaaccttattggtctgccacttacggtactt
tcaactcctgaagacaccgaggttctagtgcttgagttgggcatgaatcatgctggcgag
attaccaggctcacttctgttgctcgtccaactgtggcggtcattacaaatgttggtacc
agccacattggtcttctcggcagccgtaaaaacattgcgcgtgccaaggcagagattgtc
tctggcatgcgagcatttggttcaattgaacctacgcttattcaggcctcggcaggggat
tacaccaagttcatcgcagacaagtttgctcgtcctgctcgcgttgtttgcaagaccgtg
ggtgctacagaagatgatgtcatgagtgctcagaaggtcattcttgacgagaaaggcctt
ccaacagccactattagtgcatcttctggctggtcacgcacagtaacccttgaggtacct
ggtcgcgttgttgtcgacgaccttctcttggcgcttgaggctgtagagacgcttggcctt
gatcttgatgctgcagcagaggcaattgagcagatgccagctactcgcatgcgtctttcg
gtacttgatgctacctgtggtgccaagattattgatgactcttataacgcaagtccaaac
tcaacagctgctgctcttgatgttttaatgcagatgcccgcagagggtcgtcgcattgcg
ctcattggagagattggtgagcttggaccagaagagaagcgccttcatggatatgtgggt
gcctatattgctgctaagaacccagattttgttgcttttgtaggcacaggagcagcacgt
gaaatggttgaagcagcgcgcgttatgggcttctcggaagataaaattgaacagtttaat
gatgttaatgaagcgcttgccgtactcgggccagtactgaaacaaggagatgttcttctc
gccaaggcatctaggtctgcccagcttgatatttttgtcaaaggagttaccgagtaa
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