Actinomyces radicidentis: AXF14_09020
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Entry
AXF14_09020 CDS
T04288
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
ard
Actinomyces radicidentis
Pathway
ard00300
Lysine biosynthesis
ard00550
Peptidoglycan biosynthesis
ard01100
Metabolic pathways
ard01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
ard00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
AXF14_09020
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
AXF14_09020
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
AXF14_09020
Enzymes [BR:
ard01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
AXF14_09020
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AMD87698
UniProt:
A0A0X8JF55
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Position
2106315..2107832
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AA seq
505 aa
AA seq
DB search
MIERSLTELAAMVGGEILDADGTGDAPVVASVVTDSRKAGPGALFVAIAGERTDGHAHLG
GVLAAGGAAALVSDLPAARAALDAAGVAPDDADGERRTLPLILVEDTVEALGLLARAHLA
DLRERAASRGSELTVVAMTGSVGKTTTKDLTRQLLAAQAPTVAPIASFNNEIGLPLTVLE
TDESTRYLVLEMGASGFGHISYLTGIAPLDAAAVLMIGHAHMGGFGSVDGVAEAKSEIVQ
GLLPGGTAVLNYDDERAWAMRAIAPGPVLAFSASGDPAAEIRAENVEADAQAHAVLDLVA
PGAPTTRVRLGLPGLHNVGNALAAVGLAIAAGVPAADAVAALAGARIESPHRLDVRTVGA
PDGGDILLIDDSYNANIDSMSASLASLPALAGERRRVVVISEMLELGEFSDADHARTGEL
VADAGASLLVTIGEGAAPAAETARRAGVGEVVELPDADAALTRIDALVRAGDAVLVKGSN
GSGAWRVANHLAERPVEGTPGGTDR
NT seq
1518 nt
NT seq
+upstream
nt +downstream
nt
atgatcgagcgcagcctcaccgagctcgccgccatggtcggcggcgagatcctcgacgcg
gacgggaccggggacgccccggtcgtcgcctccgtcgtgaccgactcccgcaaggccggt
cccggcgcgctcttcgtcgccatcgccggcgagcgcacggacggccacgcccacctcggc
ggcgtcctcgccgcagggggcgcggccgccctcgtctccgacctgcccgccgcccgcgcc
gccctcgacgcggccggcgtcgcgccggacgacgcggacggagagcgccgcacgctgccc
ctcatcctcgtcgaggacacggtcgaggccctcggactgctcgccagggcgcacctcgcc
gacctgcgcgagcgcgccgcctcccgcgggagcgagctcaccgtcgtcgccatgaccggc
agcgtcggcaagacgacgacgaaggacctcacccgccagctcctcgccgcccaggcgccg
accgtcgcgccgatcgcctccttcaacaacgagatcgggctgcccctcacggtcctcgag
actgacgagtcgacccggtacctcgtcctcgagatgggcgcctccggcttcgggcacatc
tcctacctcaccggcatcgccccgctcgacgccgcggccgtcctcatgatcggccacgcc
cacatgggcggcttcggctccgtcgacggcgtcgccgaggccaagtccgagatcgtccag
ggcctcctgcccggcggcaccgccgtcctcaactacgacgacgagcgcgcctgggccatg
cgcgcgatcgcccccggcccggtgctggccttctccgcgagcggcgacccggccgccgag
atccgcgccgagaacgtcgaggccgacgcccaggcgcacgccgtcctcgacctcgtcgcc
cccggcgcgccgacgacgcgcgtccggctcgggctgcccggcctgcacaacgtcggcaac
gcgctcgccgcggtcggcctcgcgatcgccgcgggagtccctgccgccgacgccgtggcc
gcactcgcgggagcacggatcgagagcccccaccgtctcgacgtgcgcaccgtgggcgcg
cccgacggcggcgatatcctcctcatcgacgactcctacaacgccaacatcgactccatg
tcggcctccctggcctccctgccggccctggccggggagcggcgccgcgtcgtcgtcatc
tccgagatgctcgagctcggcgagttctcggacgccgaccacgcacgcaccggcgagctc
gtggccgacgccggcgcgagcctcctcgtcaccatcggggagggggccgccccggccgcc
gagaccgcccgacgggccggcgtgggcgaggtcgtcgagcttcccgacgccgacgccgcc
ctgacgcggatcgacgccctcgtgcgcgccggcgacgccgtgctcgtcaagggctccaac
ggctcgggcgcctggcgcgtcgccaaccacctcgctgaacgacccgtcgaagggacaccg
ggaggcaccgaccgatga
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