Arthrobacter sp. ERGS1 01: AL755_08240
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Entry
AL755_08240 CDS
T04085
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
are
Arthrobacter sp. ERGS1:01
Pathway
are00300
Lysine biosynthesis
are00550
Peptidoglycan biosynthesis
are01100
Metabolic pathways
are01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
are00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
AL755_08240
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
AL755_08240
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
AL755_08240
Enzymes [BR:
are01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
AL755_08240
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ALE05469
UniProt:
A0A0M4LK80
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Position
970994..972493
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AA seq
499 aa
AA seq
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MIELTAAEVAALSNGRLSAGTDPATPINVAHIVTDSRDAVPGSMYVAKAGENADGHDFMA
AAFAAGAILALAEREVAADDAGTLHPAVIVADAVLAMGALAAEVVRRIRAHSPLTVIGIT
GSAGKTTTKDLLAGILAPLAPTVAPVGSYNGEVGVPLTVFRAVEATRYLIIEMGATKMGQ
ITYLSSLVNPDIGVVLCVGSAHAGEFGSIDNIAVAKGELVEALPAHGTAILNYDDARVRA
MAARANAPVTFFSSADANEASTVPTVQARAVRTTDGHPEFDLGFPGAPDSFPVSSKLLGL
HHVTNLLAAATAAHAAGATPADIAASLSTQSAASRYRMERTDRPDGVTVINDAYNANPES
MRAALRTLAELGAGGTRRTWAVLGEMLELGEDSVLEHDAVGRVAVRLNISRLIVVGTPAR
AMHVGAVMEGSWGEESMFVPDAEAAYELLERELAPGDIVLVKSSNGAGLRFLGDRIALPG
RPAPAETNEQNSGERTQQP
NT seq
1500 nt
NT seq
+upstream
nt +downstream
nt
atgattgaacttaccgcggccgaggttgccgcacttagcaatggccgtttgtccgccggc
accgacccggcaacccccatcaacgtcgcccacatcgtgaccgattcccgggacgccgtg
cccgggagcatgtacgttgccaaagcgggggaaaacgccgacggccatgacttcatggcc
gccgcgtttgccgccggcgccatcctggccctggccgagcgcgaggttgccgcggacgac
gccggcaccctgcaccccgccgtgatcgtcgccgacgccgtgctcgccatgggcgccctg
gccgccgaggtggtgcgccgcatccgcgcgcattcacccctgacggtcatcggcatcacc
ggttccgccggtaagaccaccacgaaggacctgctggccggcatcctggccccgctggca
cccaccgtggcccccgttggctcctacaacggcgaggtgggtgtcccgctgacggtcttc
cgtgccgtggaagccacccgctatctcatcatcgagatgggcgccaccaagatgggccag
atcacctacctctcgtcactggtcaaccccgacatcggcgtggtcctgtgcgtgggcagc
gcccacgccggcgaattcggctccatcgacaacatcgccgtcgccaagggtgagctcgtc
gaggcgctgcccgcccacggcaccgcaatcctgaactacgacgacgcccgcgtccgtgcc
atggccgcccgcgccaatgcgcccgtcacgttcttctccagcgccgacgccaatgaagcc
tcgacggtacccaccgtccaggcccgggctgtgcgcaccaccgacggacacccggaattt
gacctcggcttccccggcgcccccgacagtttcccggtcagcagcaagctcctgggcctg
caccacgtgaccaacctgctggcggccgcaaccgccgcccacgcggccggggcgacaccg
gcggatattgccgcgtccctgtccacgcaaagtgccgcgagccggtaccggatggaacgc
accgaccggcccgacggcgtcaccgtcatcaacgacgcctacaacgccaaccccgaatcc
atgcgcgccgcgctgcggaccctggccgaacttggtgccggcggcacccggcgcacctgg
gccgtgctgggggagatgctcgaactcggcgaggactccgtcctggagcatgacgccgtg
ggccgcgtggccgtccggcttaacatttcccggctgatcgtggtgggcacacccgcccgc
gccatgcatgtcggggccgtcatggaaggctcctggggcgaggaatcaatgttcgtcccc
gacgccgaggccgcctacgagctgctggaacgcgaacttgcccccggcgacatcgtgctc
gtcaagtcatcaaacggcgccgggctgcggttcctgggcgatcggatagcattacccgga
agacccgcccccgctgaaaccaacgaacaaaactccggtgaaaggacccagcagccatga
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